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The atypical adhesion GPCR ADGRA1 controls hippocampal inhibitory circuit function

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1. scibot 19 May 2026
  
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  DOI: 10.1016/j.celrep.2026.117255
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13178472/
Apr 2026
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2026.03.23.713591.full-html.html

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  DOI: 10.64898/2026.03.23.713591
  
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54.241.53.176/e583a14afdc4fabf54fb98e28959712dad965ac3/2026.03.23.713591.full-html.html
Feb 2026
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Juvenile-to-adult refinement of thalamic reticular circuits via LRRTM3 enables high-resolution sensory encoding

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1. scibot 19 Feb 2026
  
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  DOI: 10.1016/j.neuron.2025.12.020
  
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sciencedirect.com/science/article/pii/S0896627325009766
Jan 2026
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Plasticity of synapses innervating spinal motor neurons after spinal cord injury in rhesus monkeys

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1. scibot 13 Jan 2026
  
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  DOI: 10.1093/jnen/nlaf128
  
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dx.doi.org/10.1093/jnen/nlaf128
Dec 2025
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Aberrant hypothalamic neuronal activity blunts glucocorticoid diurnal rhythms in murine breast cancer

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1. scibot 16 Dec 2025
  
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  DOI: 10.1016/j.neuron.2025.11.019
  
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sciencedirect.com:5037/science/article/pii/S089662732500892X
Oct 2025
www.pnas.org www.pnas.org

Hide-and-Seek genome editing reveals that Gephyrin is required for axo-axonic synapse assembly

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1. scibot 29 Oct 2025
  
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  DOI: 10.1073/pnas.2500726122
  
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pnas.org/doi/abs/10.1073/pnas.2500726122
Sep 2025
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Dysregulation of astrocyte-secreted pleiotrophin contributes to neuronal structural and functional deficits in Down syndrome

1
1. scibot 19 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116300
  
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sciencedirect.com/science/article/pii/S221112472501071X
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Arcuate dopaminergic/GABAergic neurons project within the hypothalamus and to the median eminence

1
1. scibot 07 Sep 2025
  
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  DOI: 10.1152/jn.00086.2024
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11427037/
Jul 2025
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Chronic benzodiazepine treatment triggers gephyrin scaffold destabilization and GABAAR subsynaptic reorganization

1
1. scibot 20 Jul 2025
  
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  DOI: 10.3389/fncel.2025.1624813
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12271172/
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PD-linked LRRK2 G2019S mutation impairs astrocyte morphology and synapse maintenance via ERM hyperphosphorylation

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1. scibot 16 Jul 2025
  
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  DOI: 10.7554/eLife.107556.1
  
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elifesciences.org/reviewed-preprints/107556
May 2025
www.jneurosci.org www.jneurosci.org

A critical role of Neuroligin 2 C-terminus in OCD and social behavior

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1. scibot 30 May 2025
  
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  DOI: 10.1523/JNEUROSCI.1417-24.2025
  
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jneurosci.org/content/45/19/e1417242025
Apr 2025
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Meningeal lymphatics-microglia axis regulates synaptic physiology

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1. scibot 01 Apr 2025
  
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  DOI: 10.1016/j.cell.2025.02.022
  
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sciencedirect.com/science/article/pii/S0092867425002107
Mar 2025
onlinelibrary.wiley.com onlinelibrary.wiley.com

GABA and Glycine Synaptic Release on Axotomized Motoneuron Cell Bodies Promotes Motor Axon Regeneration

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1. scibot 13 Mar 2025
  
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  DOI: 10.1111/ejn.70045
  
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onlinelibrary.wiley.com/doi/10.1111/ejn.70045
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The effects of amyloidosis and aging on glutamatergic and GABAergic synapses, and interneurons in the barrel cortex and non-neocortical brain regions

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1. scibot 08 Mar 2025
  
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  RRID:AB_887873
  
  DOI: 10.3389/fnana.2025.1526962
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11863279/
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Modelling a pathological GSX2 variant that selectively alters DNA binding reveals hypomorphic mouse brain defects

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1. scibot 08 Mar 2025
  
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  RRID:AB_887873
  
  DOI: 10.1242/dmm.052110
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11876842/
journals.lww.com journals.lww.com

The compound... : Neural Regeneration Research

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1. scibot 06 Mar 2025
  
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  RRID:AB_887873
  
  DOI: 10.4103/NRR.NRR-D-23-01890
  
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journals.lww.com/nrronline/fulltext/2025/11000/the_compound.34.aspx
Feb 2025
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Haploinsufficiency of GABAA receptor-associated Clptm1 enhances phasic and tonic inhibitory neurotransmission, suppresses excitatory synaptic plasticity, and impairs memory

1
1. scibot 11 Feb 2025
  
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  RRID:AB_887873
  
  DOI: 10.1523/JNEUROSCI.0521-24.2024
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11308325/
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The endocytic adaptor AP-2 maintains Purkinje cell function by balancing cerebellar parallel and climbing fiber synapses

1
1. scibot 07 Feb 2025
  
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  RRID:AB_887873
  
  DOI: 10.1016/j.celrep.2025.115256
  
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sciencedirect.com/science/article/pii/S2211124725000270
Jan 2025
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Differential Neuronal Activation of Nociceptive Pathways in Neuropathic Pain After Spinal Cord Injury

1
1. scibot 31 Jan 2025
  
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  RRID:AB_887873
  
  DOI: 10.1007/s10571-025-01532-6
  
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link.springer.com/article/10.1007/s10571-025-01532-6
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Cd99l2 regulates excitatory synapse development and restrains immediate-early gene activation

1
1. scibot 14 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115155
  
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sciencedirect.com/science/article/pii/S2211124724015067
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Sex-specific astrocyte regulation of spinal motor circuits by Nkx6.1

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1. scibot 03 Jan 2025
  
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  RRID:AB_887873
  
  DOI: 10.1016/j.celrep.2024.115121
  
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sciencedirect.com/science/article/pii/S2211124724014724
Dec 2024
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Neuroanatomical Substrates of Circuit-Specific Cholinergic Modulation across the Primate Anterior Cingulate Cortex

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1. scibot 13 Dec 2024
  
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  DOI: 10.1523/JNEUROSCI.0953-23.2024
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11170673/
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Characterizing and targeting glioblastoma neuron-tumor networks with retrograde tracing

1
1. scibot 10 Dec 2024
  
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  DOI: 10.1016/j.cell.2024.11.002
  
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sciencedirect.com/science/article/pii/S0092867424012765
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Spinal V1 inhibitory interneuron clades differ in birthdate, projections to motoneurons, and heterogeneity

1
1. scibot 05 Dec 2024
  
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  RRID:AB_887873
  
  DOI: 10.7554/eLife.95172
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11604222/
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Loss of mitochondrial enzyme GPT2 leads to reprogramming of synaptic glutamate metabolism

1
1. scibot 05 Dec 2024
  
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  RRID:AB_887873
  
  DOI: 10.1186/s13041-024-01154-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11600823/
Nov 2024
www.biorxiv.org www.biorxiv.org

Loss of mitochondrial enzyme GPT2 leads to reprogramming of synaptic glutamate metabolism

1
1. scibot 14 Nov 2024
  
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  RRID:AB_887873
  
  DOI: 10.1101/2024.11.06.622291
  
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biorxiv.org/content/10.1101/2024.11.06.622291v1
Oct 2024
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The TMEM132B-GABAA receptor complex controls alcohol actions in the brain

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1. scibot 02 Oct 2024
  
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  DOI: 10.1016/j.cell.2024.09.006
  
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  DOI: 10.1016/j.cell.2024.09.006
  
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sciencedirect.com/science/article/pii/S0092867424010249
Sep 2024
onlinelibrary.wiley.com onlinelibrary.wiley.com

Dopamine Depletion induces Neuron‐specific Alterations of GABAergic Transmission in the Mouse Striatum

1
1. scibot 25 Sep 2024
  
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  RRID:AB_887873
  
  DOI: 10.1111/ejn.14886
  
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  Curator comments: Anti-VAChT antibody Synaptic Systems Cat# 139 103
  
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onlinelibrary.wiley.com/doi/10.1111/ejn.14886
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Biphasic Impact of Prenatal Inflammation and Macrophage Depletion on the Wiring of Neocortical Inhibitory Circuits

1
1. scibot 25 Sep 2024
  
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  RRID:AB_1106810
  
  DOI: 10.1016/j.celrep.2019.06.086
  
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sciencedirect.com/science/article/pii/S2211124719308666
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SynBot is an open-source image analysis software for automated quantification of synapses

1
1. scibot 10 Sep 2024
  
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  AB_887873
  
  DOI: 10.1016/j.crmeth.2024.100861
  
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sciencedirect.com/science/article/pii/S266723752400239X
Aug 2024
onlinelibrary.wiley.com onlinelibrary.wiley.com

In vivo clonal overexpression of neuroligin 3 and neuroligin 2 in neurons of the rat cerebral cortex: Differential effects on GABAergic synapses and neuronal migration

1
1. scibot 02 Aug 2024
  
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  DOI: 10.1002/cne.23740
  
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onlinelibrary.wiley.com/doi/10.1002/cne.23740/full
Apr 2024
www.cell.com www.cell.com

Astrocyte-secreted neurocan controls inhibitory synapse formation and function

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1. scibot 04 Apr 2024
  
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  DOI: 10.1016/j.neuron.2024.03.007
  
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cell.com/neuron/fulltext/S0896-6273(24)00161-2
Mar 2024
elifesciences.org elifesciences.org

Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer's disease, restores synapse integrity and memory in a disease mouse model

2
1. scibot 01 Mar 2024
  
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  RRID: AB_887873
  
  DOI: 10.7554/eLife.89453
  
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  DOI: 10.7554/eLife.89453
  
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elifesciences.org/articles/89453
Feb 2024
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Different Purkinje cell pathologies cause specific patterns of progressive gait ataxia in mice

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1. scibot 02 Feb 2024
  
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  AB_887873
  
  DOI: 10.1016/j.nbd.2024.106422
  
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sciencedirect.com/science/article/pii/S0969996124000214
Jan 2024
www.sciencedirect.com www.sciencedirect.com

Developmental transformation of Ca2+ channel-vesicle nanotopography at a central GABAergic synapse

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1. scibot 19 Jan 2024
  
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Synaptotagmin 9 Modulates Spontaneous Neurotransmitter Release in Striatal Neurons by Regulating Substance P Secretion

1
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LRRC37B is a human modifier of voltage-gated sodium channels and axon excitability in cortical neurons

1
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Nov 2023
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Preclinical Long-Term Safety of Intraspinal Transplantation of Human Dorsal Spinal GABA Neural Progenitor Cells

1
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The proteomic landscape of synaptic diversity across brain regions and cell types

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Oct 2023
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Increased hippocampal cannabinoid 1 receptor expression is associated with protection from severe seizures in pregnant mice with reduced uterine perfusion pressure

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Mesenchymal-derived extracellular vesicles enhance microglia-mediated synapse remodeling after cortical injury in aging Rhesus monkeys

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Aug 2023
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Machine learning identifies experimental brain metastasis subtypes based on their influence on neural circuits

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Adamtsl3 mediates DCC signaling to selectively promote GABAergic synapse function

2
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Jul 2023
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Selective deletion of zinc transporter 3 in amacrine cells promotes retinal ganglion cell survival and optic nerve regeneration after injury

1
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Generation of mouse hippocampal brain organoids from primary embryonic neural stem cells

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Alternative splicing and heparan sulfation converge on neurexin-1 to control glutamatergic transmission and autism-related behaviors

1
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Jun 2023
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Mesenchymal-Derived Extracellular Vesicles Enhance Microglia-mediated Synapse Remodeling after Cortical Injury in Rhesus Monkeys

1
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Protecting RNA quality for spatial transcriptomics while improving immunofluorescent staining quality

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May 2023
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Post-weaning social isolation in male mice leads to abnormal aggression and disrupted network organization in the prefrontal cortex: Contribution of parvalbumin interneurons with or without perineuronal nets

1
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SLITRK2 variants associated with neurodevelopmental disorders impair excitatory synaptic function and cognition in mice

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  DOI: 10.1038/s41467-022-31566-z
  
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Apr 2023
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Glioma epileptiform activity and progression are driven by IGSF3-mediated potassium dysregulation

1
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Microglia enable cross-modal plasticity by removing inhibitory synapses

1
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Feb 2023
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GEARBOCS: An Adeno Associated Virus Tool for In Vivo Gene Editing in Astrocytes

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Jan 2023
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SSRN-id4232469-html.html

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Nov 2022
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Thoracic VGlut2+ spinal interneurons regulate structural and functional plasticity of sympathetic networks after high-level spinal cord injury

1
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Dually innervated dendritic spines develop in the absence of excitatory activity and resist plasticity through tonic inhibitory crosstalk

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Sep 2022
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Spinal cord synaptic plasticity by GlyRβ release from receptor fields and syndapin I-dependent uptake

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Aug 2022
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JNEUROSCI.2060-21.2022.full-html.html

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Jul 2022
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Dendritic Inhibition by Shh Signaling-Dependent Stellate Cell Pool Is Critical for Motor Learning

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Jun 2022
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Brevican, Neurocan, Tenascin-C, and Tenascin-R Act as Important Regulators of the Interplay Between Perineuronal Nets, Synaptic Integrity, Inhibitory Interneurons, and Otx2

1
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May 2022
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Targeted proteoform mapping uncovers specific Neurexin-3 variants required for dendritic inhibition

1
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MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior

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Apr 2022
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The metabolite p-cresol impairs dendritic development, synaptogenesis and synapse function in hippocampal neurons: Implications for autism spectrum disorder.

1
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Feb 2022
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Prepubescent female rodents have enhanced hippocampal LTP and learning relative to males, reversing in adulthood as inhibition increases

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Jan 2022
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Muscarinic Acetylcholine Receptor Localization on Distinct Excitatory and Inhibitory Neurons Within the ACC and LPFC of the Rhesus Monkey

1
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Clathrin-independent endocytic retrieval of SV proteins mediated by the clathrin adaptor AP-2 at mammalian central synapses

1
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  DOI: 10.7554/eLife.71198
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8752090/
Dec 2021
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Stepwise disassembly of GABAergic synapses during pathogenic excitotoxicity

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Murine cerebral organoids develop network of functional neurons and hippocampal brain region identity

1
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  DOI: 10.1016/j.isci.2021.103438
  
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Central synaptopathy is the most conserved feature of motor circuit pathology across spinal muscular atrophy mouse models

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ncbi.nlm.nih.gov/pmc/articles/PMC8605199/
Oct 2021
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Tau reduction affects excitatory and inhibitory neurons differently, reduces excitation/inhibition ratios, and counteracts network hypersynchrony

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Layer-specific pyramidal neuron properties underlie diverse anterior cingulate cortical motor and limbic networks

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Sparsification of AP firing in adult-born hippocampal granule cells via voltage-dependent α5-GABAA receptors

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Systemic inflammation induced the delayed reduction of excitatory synapses in the CA3 during ageing

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Cannabinoid receptor 2 deletion influences social memory and synaptic architecture in the hippocampus

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Untitled document

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Jul 2021
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Cell type‐specific distribution of GABAA receptor subtypes in the mouse dorsal striatum

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Untitled document

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In vivo transgenic expression of collybistin in neurons of the rat cerebral cortex

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Action potential-coupled Rho GTPase signaling drives presynaptic plasticity

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Selective overexpression of Collybistin in mouse hippocampal pyramidal cells enhances GABAergic neurotransmission and protects against PTZ-induced seizures

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Nutritional regulation of oligodendrocyte differentiation regulates perineuronal net remodeling in the median eminence

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Dysregulation of GABAA Receptor-Mediated Neurotransmission during the Auditory Cortex Critical Period in the Fragile X Syndrome Mouse Model

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HepaCAM controls astrocyte self-organization and coupling

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Transient developmental imbalance of cortical interneuron subtypes presages long-term changes in behavior

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May 2021
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Midbrain dopaminergic inputs gate amygdala intercalated cell clusters by distinct and cooperative mechanisms in male mice

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Presynaptic store-operated Ca2+ entry drives excitatory spontaneous neurotransmission and augments endoplasmic reticulum stress

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Pathogenic GRM7 mutations associated with neurodevelopmental disorders impair axon outgrowth and presynaptic terminal development

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Neddylation is required for presynaptic clustering of mGlu7 and maturation of presynaptic terminals

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Poly I:C Activated Microglia Disrupt Perineuronal Nets and Modulate Synaptic Balance in Primary Hippocampal Neurons in vitro

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Pulse-Chase Proteomics of the App Knockin Mouse Models of Alzheimer’s Disease Reveals that Synaptic Dysfunction Originates in Presynaptic Terminals

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Synaptic organisation and behaviour-dependent activity of mGluR8a-innervated GABAergic trilaminar cells projecting from the hippocampus to the subiculum

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Peculiar protrusions along tanycyte processes face diverse neural and non‐neural cell types in the hypothalamic parenchyma

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A High-Resolution Method for Quantitative Molecular Analysis of Functionally Characterized Individual Synapses

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Poly I:C induced maternal immune challenge reduces perineuronal net area and raises spontaneous network activity of hippocampal neurons in vitro

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Striatal Projection Neurons Require Huntingtin for Synaptic Connectivity and Survival

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Treatment with mesenchymal-derived extracellular vesicles reduces injury-related pathology in pyramidal neurons of monkey perilesional ventral premotor cortex EVs reduce injury-related pathology in vPMC

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NPAS4 recruits CCK basket cell synapses and enhances cannabinoid-sensitive inhibition in the mouse hippocampus

1
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Expression of Protocadherin‐γC4 protein in the rat brain

1
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Distinct Nanoscale Calcium Channel and Synaptic Vesicle Topographies Contribute to the Diversity of Synaptic Function

1
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Distinct Pathogenic Genes Causing Intellectual Disability and Autism Exhibit a Common Neuronal Network Hyperactivity Phenotype

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Elimination of the four extracellular matrix molecules tenascin-C, tenascin-R, brevican and neurocan alters the ratio of excitatory and inhibitory synapses

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A proline-rich motif on VGLUT1 reduces synaptic vesicle super-pool and spontaneous release frequency

1
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The X-Linked Intellectual Disability Gene Zdhhc9 Is Essential for Dendrite Outgrowth and Inhibitory Synapse Formation

1
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Specific synaptic input strengths determine the computational properties of excitation–inhibition integration in a sound localization circuit

1
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Spinal Neuropeptide Y1 Receptor-Expressing Neurons Form an Essential Excitatory Pathway for Mechanical Itch

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Identification of a Core Amino Acid Motif within the α Subunit of GABAARs that Promotes Inhibitory Synaptogenesis and Resilience to Seizures

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The Classical Complement Pathway Mediates Microglia-Dependent Remodeling of Spinal Motor Circuits during Development and in SMA

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  DOI: 10.1113/JP276012
  
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Cell type‐specific distribution of GABAA receptor subtypes in the mouse dorsal striatum

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  DOI: 10.1002/cne.24665
  
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Hapln4/Bral2 is a selective regulator for formation and transmission of GABAergic synapses between Purkinje and deep cerebellar nuclei neurons

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  DOI: 10.1111/jnc.14571
  
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Axo-axonic Innervation of Neocortical Pyramidal Neurons by GABAergic Chandelier Cells Requires AnkyrinG-Associated L1CAM

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  DOI: 10.1016/j.neuron.2019.02.009
  
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Expression of Neurofilament Subunits at Neocortical Glutamatergic and GABAergic Synapses

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VIP-immunoreactive interneurons within circuits of the mouse basolateral amygdala

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Shared rhythmic subcortical GABAergic input to the entorhinal cortex and presubiculum

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RIM C2B Domains Target Presynaptic Active Zone Functions to PIP2-Containing Membranes

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Molecular Dissection of Neuroligin 2 and Slitrk3 Reveals an Essential Framework for GABAergic Synapse Development

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Glutamate-induced and NMDA receptor-mediated neurodegeneration entails P2Y1 receptor activation

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nature.com/articles/s41419-018-0351-1
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Behavior-Dependent Activity and Synaptic Organization of Septo-hippocampal GABAergic Neurons Selectively Targeting the Hippocampal CA3 Area

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RORβ Spinal Interneurons Gate Sensory Transmission during Locomotion to Secure a Fluid Walking Gait

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Clptm1 Limits Forward Trafficking of GABAA Receptors to Scale Inhibitory Synaptic Strength

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Mitochondrial Ultrastructure Is Coupled to Synaptic Performance at Axonal Release Sites

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Untitled document

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Inhibitory and excitatory amino acid neurotransmitters are utilized by the projection from the dorsal deep mesencephalic nucleus to the sublaterodorsal nucleus REM sleep induction zone

1
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  SYSY131004
  
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sciencedirect.com/science/article/pii/S0006899314005149
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PTEN Loss Increases the Connectivity of Fast Synaptic Motifs and Functional Connectivity in a Developing Hippocampal Network

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  RRID:AB_887873
  
  Curator: @patriciaelyse_
  
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jneurosci.org/content/37/36/8595
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Assembly rules for GABAA receptor complexes in the brain

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  AB_887873
  
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Strength and diversity of inhibitory signaling differentiates primate anterior cingulate from lateral prefrontal cortex

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jneurosci.org/content/37/18/4717
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Synaptotagmin2 (Syt2) Drives Fast Release Redundantly with Syt1 at the Output Synapses of Parvalbumin-Expressing Inhibitory Neurons

1
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  AB_887873
  
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Untitled document

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eneuro.org/content/4/1/ENEURO.0194-16.2017
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Activation-Dependent Rapid Postsynaptic Clustering of Glycine Receptors in Mature Spinal Cord Neurons

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  AB_887873
  
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Combined Treatment With Environmental Enrichment and (-)-Epigallocatechin-3-Gallate Ameliorates Learning Deficits and Hippocampal Alterations in a Mouse Model of Down Syndrome

1
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ncbi.nlm.nih.gov/pmc/articles/PMC5099603/
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Somatodendritic Expression of JAM2 Inhibits Oligodendrocyte Myelination

1
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  AB_887873
  
  Curator: @gabimpine
  
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ELKS controls the pool of readily releasable vesicles at excitatory synapses through its N-terminal coiled-coil domains

1
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  AB_887873
  
  Curator: @gabimpine
  
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ncbi.nlm.nih.gov/pmc/articles/PMC4935463/
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Cell adhesion molecule contactin‐associated protein 3 is expressed in the mouse basal ganglia during early postnatal stages

1
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  AB_887873
  
  Curator: @jcabotaj
  
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onlinelibrary.wiley.com/doi/10.1002/jnr.23670/full
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In vivo clonal overexpression of neuroligin 3 and neuroligin 2 in neurons of the rat cerebral cortex: Differential effects on GABAergic synapses and neuronal migration

1
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  AB_887873
  
  Curator: @gabimpine
  
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onlinelibrary.wiley.com/doi/10.1002/cne.23740/full
Nov 2016
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Somatodendritic Expression of JAM2 Inhibits Oligodendrocyte Myelination

1
1. scibot 04 Nov 2016
  
  in Public
  
  AB_887873
  
  Proper Citation: (Synaptic Systems Cat# 131 004, RRID:AB_887873)
  Antibody ID: AB_887873
  Cat Num: 131 004
  Clonality: polyclonal antibody
  Comments: manufacturer recommendations: Immunocytochemistry; Immunohistochemistry; Western Blot; Western Blot, Immunocytochemistry, Immunohistochemistry mouse, rat, rat, mouse
  Host Organism: guinea pig
  Proper Citation: (Synaptic Systems Cat# 131 004, RRID:AB_887873)
  Reference: PMID:18634004
  Reference: PMID:18634004
  Target Antigen: VGAT. cytoplasmic domain
  Vendor: Synaptic Systems
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Annotators

URL

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Annotators

URL

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Annotators

URL

Tags

Annotators

URL

Tags

Annotators