86 Matching Annotations
  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The disruptive effects of COPD exacerbation-associated factors on epithelial repair responses
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    1. scibot 03 Jul 2024
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      DOI: 10.3389/fimmu.2024.1346491

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    ncbi.nlm.nih.gov/pmc/articles/PMC11193328/
  3. Apr 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Tracing the origin of alveolar stem cells in lung repair and regeneration
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    sciencedirect.com/science/article/pii/S0092867424003027
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    Vangl-dependent mesenchymal thinning shapes the distal lung during murine sacculation
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    sciencedirect.com/science/article/pii/S1534580724001783
  6. Mar 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology progression
    1
    1. scibot 06 Mar 2024
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      DOI: 10.1186/s40035-024-00403-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC10910783/
  8. Feb 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Adeno-to-squamous transition drives resistance to KRAS inhibition in LKB1 mutant lung cancer
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    1. scibot 23 Feb 2024
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    sciencedirect.com/science/article/pii/S1535610824000369
  10. www.sciencedirect.com www.sciencedirect.com
    Stem cell migration drives lung repair in living mice
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    sciencedirect.com/science/article/pii/S1534580724000741
  11. Jan 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRDM3/16 Regulate Chromatin Accessibility Required for NKX2-1 Mediated Alveolar Epithelial Differentiation and Function
    1
    1. scibot 20 Jan 2024
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      DOI: 10.1101/2023.12.20.570481

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    ncbi.nlm.nih.gov/pmc/articles/PMC10769259/
  13. link.springer.com link.springer.com
    Med23 deficiency reprograms the tumor microenvironment to promote lung tumorigenesis
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    1. scibot 11 Jan 2024
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    link.springer.com/article/10.1038/s41416-023-02556-9
  14. Dec 2023
  15. www.sciencedirect.com www.sciencedirect.com
    Human inherited CCR2 deficiency underlies progressive polycystic lung disease
    1
    1. scibot 29 Dec 2023
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    sciencedirect.com/science/article/pii/S0092867423013235
  16. Nov 2023
  17. www.sciencedirect.com www.sciencedirect.com
    Human pluripotent stem cell fate trajectories toward lung and hepatocyte progenitors
    1
    1. scibot 29 Nov 2023
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      DOI: 10.1016/j.isci.2023.108205

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    sciencedirect.com/science/article/pii/S2589004223022824
  18. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Neuropeptide stimulation of physiological and immunological responses in precision-cut lung slices
    1
    1. scibot 25 Nov 2023
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    physoc.onlinelibrary.wiley.com/doi/10.14814/phy2.15873
  19. Oct 2023
  20. www.biorxiv.org www.biorxiv.org
    LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology spread
    1
    1. scibot 13 Oct 2023
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      DOI: 10.1101/2023.10.06.561190

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    biorxiv.org/content/10.1101/2023.10.06.561190v1
  21. Aug 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Inhalation of ACE2 as a therapeutic target on sex-bias differences in SARS-CoV-2 infection and variant of concern
    1
    1. scibot 10 Aug 2023
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      DOI: 10.1016/j.isci.2023.107470

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    sciencedirect.com/science/article/pii/S258900422301547X
  23. www.sciencedirect.com www.sciencedirect.com
    Enhanced glycolysis-mediated energy production in alveolar stem cells is required for alveolar regeneration
    1
    1. scibot 04 Aug 2023
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      DOI: 10.1016/j.stem.2023.07.007

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    sciencedirect.com/science/article/pii/S1934590923002539
  24. Jul 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Tissue specificity of oncogenic BRAF targeted to lung and thyroid through a shared lineage factor
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    1. scibot 01 Jul 2023
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      DOI: 10.1016/j.isci.2023.107071

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    sciencedirect.com/science/article/pii/S2589004223011483
  26. Jun 2023
  27. www.sciencedirect.com www.sciencedirect.com
    Distinct immune microenvironment of lung adenocarcinoma in never-smokers from smokers
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      DOI: 10.1016/j.xcrm.2023.101078

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    sciencedirect.com/science/article/pii/S2666379123001970
  28. 52.53.155.43 52.53.155.43
    Generation and expansion of transitional lung organoids from human pluripotent stem cells
    1
    1. scibot 07 Jun 2023
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      DOI: 10.1101/2023.01.30.526265

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    52.53.155.43/ba62128acd6e3f7c070d6d9a373799060570fdfd/2023.01.30.526265v1.full-html.html
  29. May 2023
  30. www.nature.com www.nature.com
    A prime editor mouse to model a broad spectrum of somatic mutations in vivo
    1
    1. scibot 13 May 2023
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      DOI: 10.1038/s41587-023-01783-y

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    nature.com/articles/s41587-023-01783-y
  31. Apr 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Dysregulated lung stroma drives emphysema exacerbation by potentiating resident lymphocytes to suppress an epithelial stem cell reservoir
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    1. scibot 20 Apr 2023
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      DOI: 10.1016/j.immuni.2023.01.032

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    sciencedirect.com/science/article/pii/S1074761323000444
  33. Mar 2023
  34. 52.53.155.43 52.53.155.43
    Generation and expansion of transitional lung organoids from human pluripotent stem cells
    3
    1. scibot 08 Mar 2023
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      DOI: 10.1101/2023.01.30.526265

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      RRID:AB_91

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      DOI: 10.1101/2023.01.30.526265

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    52.53.155.43/ba62128acd6e3f7c070d6d9a373799060570fdfd/2023.01.30.526265v1.full-html.html
  35. www.sciencedirect.com www.sciencedirect.com
    Biophysical forces mediated by respiration maintain lung alveolar epithelial cell fate
    1
    1. scibot 04 Mar 2023
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      DOI: 10.1016/j.cell.2023.02.010

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    sciencedirect.com/science/article/pii/S0092867423001277
  36. Dec 2022
  37. www.sciencedirect.com www.sciencedirect.com
    Organoid modeling of human fetal lung alveolar development reveals mechanisms of cell fate patterning and neonatal respiratory disease
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    1. scibot 11 Dec 2022
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      DOI: 10.1016/j.stem.2022.11.013

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    sciencedirect.com/science/article/pii/S193459092200460X
  38. Nov 2022
  39. www.nature.com www.nature.com
    mTORC1 signaling facilitates differential stem cell differentiation to shape the developing murine lung and is associated with mitochondrial capacity
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    1. scibot 29 Nov 2022
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      DOI: 10.1038/s41467-022-34763-y

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    nature.com/articles/s41467-022-34763-y
  40. Oct 2022
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multi-apical polarity of alveolar stem cells and their dynamics during lung development and regeneration
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    1. scibot 02 Oct 2022
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      DOI: 10.1016/j.isci.2022.105114

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    ncbi.nlm.nih.gov/pmc/articles/PMC9519774/
  42. Jul 2022
  43. www.sciencedirect.com www.sciencedirect.com
    Klf5 defines alveolar epithelial type 1 cell lineage commitment during lung development and regeneration
    1
    1. scibot 08 Jul 2022
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      DOI: 10.1016/j.devcel.2022.06.007

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    sciencedirect.com/science/article/pii/S1534580722004476
  44. Jun 2022
  45. www.sciencedirect.com www.sciencedirect.com
    A functional circuit formed by the autonomic nerves and myofibroblasts controls mammalian alveolar formation for gas exchange
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      DOI: 10.1016/j.devcel.2022.05.021

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    sciencedirect.com/science/article/pii/S1534580722004051
  46. www.sciencedirect.com www.sciencedirect.com
    Defined conditions for long-term expansion of murine and human alveolar epithelial stem cells in three-dimensional cultures
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    1. scibot 15 Jun 2022
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      DOI: 10.1016/j.xpro.2022.101447

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    sciencedirect.com/science/article/pii/S2666166722003276
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acquisition of cellular properties during alveolar formation requires differential activity and distribution of mitochondria
    1
    1. scibot 15 Jun 2022
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      DOI: 10.7554/eLife.68598

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    ncbi.nlm.nih.gov/pmc/articles/PMC9183236/
  48. Apr 2022
  49. www.sciencedirect.com www.sciencedirect.com
    Neonatal lung-derived SSEA-1+ cells exhibited distinct stem/progenitor characteristics and organoid developmental potential
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      DOI: 10.1016/j.isci.2022.104262

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    sciencedirect.com/science/article/pii/S2589004222005326
  50. www.sciencedirect.com www.sciencedirect.com
    Hedgehog-responsive PDGFRa(+) fibroblasts maintain a unique pool of alveolar epithelial progenitor cells during alveologenesis
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      DOI: 10.1016/j.celrep.2022.110608

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    sciencedirect.com/science/article/pii/S2211124722003564
  51. Dec 2021
  52. www.embopress.org www.embopress.org
    DNA damage response at telomeres boosts the transcription of SARS-CoV-2 receptor ACE2 during aging
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      DOI: 10.15252/embr.202153658

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    embopress.org/doi/abs/10.15252/embr.202153658
  53. Nov 2021
  54. 52.53.155.43 52.53.155.43
    ajplung.00323.2020-html.html
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    52.53.155.43/17b3b487475d64b64677f736ed2d025556a24b0c/ajplung.00323.2020-html.html
  55. elifesciences.org elifesciences.org
    A functional genetic toolbox for human tissue-derived organoids
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      DOI: 10.7554/eLife.67886

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    elifesciences.org/articles/67886
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma
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      DOI: 10.7554/eLife.71596

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    ncbi.nlm.nih.gov/pmc/articles/PMC8553340/
  57. Oct 2021
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures
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      DOI: 10.7554/eLife.65811

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    ncbi.nlm.nih.gov/pmc/articles/PMC8480975/
  59. Sep 2021
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mesenchymal stromal cell aging impairs the self-organizing capacity of lung alveolar epithelial stem cells
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    1. scibot 22 Sep 2021
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      DOI: 10.7554/eLife.68049

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    ncbi.nlm.nih.gov/pmc/articles/PMC8445616/
  61. Aug 2021
  62. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A drug screen with approved compounds identifies amlexanox as a novel Wnt/β-catenin activator inducing lung epithelial organoid formation
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    1. scibot 16 Aug 2021
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      DOI: 10.1111/bph.15581

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15581
  63. link.springer.com link.springer.com
    Untitled document
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      DOI: 10.1186/s40478-019-0679-5

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    link.springer.com/article/10.1186/s40478-019-0679-5
  64. Jul 2021
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      DOI: 10.1186/s40478-019-0679-5

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      AB_3786

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  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FoxA1 and FoxA2 drive gastric differentiation and suppress squamous identity in NKX2-1-negative lung cancer
    2
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  67. f1000research.com f1000research.com
    A bilayer tissue culture model of the bovine alveolus
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  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Club cells form lung adenocarcinomas and maintain the alveoli of adult mice
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  69. actaneurocomms.biomedcentral.com actaneurocomms.biomedcentral.com
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  70. www.sciencedirect.com www.sciencedirect.com
    Interferon-λ Mediates Non-redundant Front-Line Antiviral Protection against Influenza Virus Infection without Compromising Host Fitness
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  71. link.springer.com link.springer.com
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  72. www.sciencedirect.com www.sciencedirect.com
    Recruited Monocytes and Type 2 Immunity Promote Lung Regeneration following Pneumonectomy
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  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Developmental vascular remodeling defects and postnatal kidney failure in mice lacking Gpr116 (Adgrf5) and Eltd1 (Adgrl4)
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  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Notch1 Deficiency Induces Tumor Cell Accumulation Inside the Bronchiolar Lumen and Increases TAZ Expression in an Autochthonous Kras LSL-G12V Driven Lung Cancer Mouse Model
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  75. Jun 2021
  76. www.sciencedirect.com www.sciencedirect.com
    Direct derivation of human alveolospheres for SARS-CoV-2 infection modeling and drug screening
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  77. May 2021
  78. www.sciencedirect.com www.sciencedirect.com
    Direct derivation of human alveolospheres for SARS-CoV-2 infection modeling and drug screening
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  79. www.sciencedirect.com www.sciencedirect.com
    Alveolar epithelial cell fate is maintained in a spatially restricted manner to promote lung regeneration after acute injury
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  80. Apr 2021
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    Emergence of a High-Plasticity Cell State during Lung Cancer Evolution
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  82. www.sciencedirect.com www.sciencedirect.com
    Epigenomic State Transitions Characterize Tumor Progression in Mouse Lung Adenocarcinoma
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  83. Mar 2021
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  85. Feb 2021
  86. www.cell.com www.cell.com
    Interferon-λ Mediates Non-redundant Front-Line Antiviral Protection against Influenza Virus Infection without Compromising Host Fitness
    2
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  87. www.cell.com www.cell.com
    Targeted Phage Display-Based Pulmonary Vaccination in Mice and Non-human Primates
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  88. www.sciencedirect.com www.sciencedirect.com
    Platform Effects on Regeneration by Pulmonary Basal Cells as Evaluated by Single-Cell RNA Sequencing
    1
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      AB_3786

      DOI: 10.1016/j.celrep.2020.03.004

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  89. Jan 2021
  90. www.sciencedirect.com www.sciencedirect.com
    Isolation and culture of mouse alveolar type II cells to study type II to type I cell differentiation
    1
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      DOI: 10.1016/j.xpro.2020.100241

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  91. Nov 2020
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction
    1
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      RRID:AB_91588

      DOI: 10.1016/j.stem.2020.10.005

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  93. Sep 2020
  94. www.sciencedirect.com www.sciencedirect.com
    Platform Effects on Regeneration by Pulmonary Basal Cells as Evaluated by Single-Cell RNA Sequencing
    1
    1. scibot 17 Sep 2020
      RRID:AB_91588

      DOI: 10.1016/j.celrep.2020.03.004

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  95. www.sciencedirect.com www.sciencedirect.com
    Distinct Airway Epithelial Stem Cells Hide among Club Cells but Mobilize to Promote Alveolar Regeneration
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      DOI: 10.1016/j.stem.2019.12.014

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  96. www.sciencedirect.com www.sciencedirect.com
    Angiocrine Sphingosine-1-Phosphate Activation of S1PR2-YAP Signaling Axis in Alveolar Type II Cells Is Essential for Lung Repair
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  97. www.sciencedirect.com www.sciencedirect.com
    Inflammatory Signals Induce AT2 Cell-Derived Damage-Associated Transient Progenitors that Mediate Alveolar Regeneration
    1
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      RRID:AB_91588

      DOI: 10.1016/j.stem.2020.06.020

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  98. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.14977

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  99. Jan 2020
  100. www.sciencedirect.com www.sciencedirect.com
    Rare Pulmonary Neuroendocrine Cells Are Stem Cells Regulated by Rb, p53, and Notch
    1
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      DOI: 10.1016/j.cell.2019.09.010

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  101. www.sciencedirect.com www.sciencedirect.com
    Progressive Pulmonary Fibrosis Is Caused by Elevated Mechanical Tension on Alveolar Stem Cells
    1
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      DOI: 10.1016/j.cell.2019.11.027

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  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  103. www.sciencedirect.com www.sciencedirect.com
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  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FoxA1 and FoxA2 drive gastric differentiation and suppress squamous identity in NKX2-1-negative lung cancer
    1
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  105. www.sciencedirect.com www.sciencedirect.com
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  106. Nov 2018
  107. www.sciencedirect.com www.sciencedirect.com
    The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment
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  108. stemcellsjournals.onlinelibrary.wiley.com stemcellsjournals.onlinelibrary.wiley.com
    Notch Signaling Controls Transdifferentiation of Pulmonary Neuroendocrine Cells in Response to Lung Injury
    1
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    The Strength of Mechanical Forces Determines the Differentiation of Alveolar Epithelial Cells
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  110. Nov 2017
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    Distinct Mesenchymal Lineages and Niches Promote Epithelial Self-Renewal and Myofibrogenesis in the Lung
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  112. elifesciences.org elifesciences.org
    Human embryonic lung epithelial tips are multipotent progenitors that can be expanded in vitro as long-term self-renewing organoids
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    Interferon-λ Mediates Non-redundant Front-Line Antiviral Protection against Influenza Virus Infection without Compromising Host Fitness
    1
    1. scibot 08 Nov 2017
      AB_91588

      Resource used:

      (Millipore Cat# AB3786, RRID:AB_91588)

      SciCrunch record: RRID:AB_91588

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_91588
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    URL

    sciencedirect.com/science/article/pii/S1074761317301905
  114. www.sciencedirect.com www.sciencedirect.com
    Recruited Monocytes and Type 2 Immunity Promote Lung Regeneration following Pneumonectomy
    1
    1. scibot 08 Nov 2017
      AB_91588

      Curator: @chewbeccax

      Resource used:

      (Millipore Cat# AB3786, RRID:AB_91588)

      SciCrunch record: RRID:AB_91588

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_91588 RRIDCUR:Validated
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    URL

    sciencedirect.com/science/article/pii/S1934590917300954
  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis
    1
    1. scibot 08 Nov 2017
      AB_91588

      Curator: @gabimpine

      Resource used:

      (Millipore Cat# AB3786, RRID:AB_91588)

      SciCrunch record: RRID:AB_91588

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_91588 RRIDCUR:Validated
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    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC5360446/