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Oct 2025
www.sciencedirect.com www.sciencedirect.com

A cancer-specific antigen drives histone acetylation by stabilizing the acetyltransferases

1
1. scibot 08 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116408
  
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sciencedirect.com/science/article/pii/S2211124725011799
Sep 2025
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Dynamic regulation of the oxidative stress response by the E3 ligase TRIP12

1
1. scibot 11 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116262
  
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sciencedirect.com/science/article/pii/S2211124725010332
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Coxsackievirus B infection invokes unique cell-type-specific responses in primary human pancreatic islets

1
1. scibot 03 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116211
  
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sciencedirect.com/science/article/pii/S2211124725009829
Aug 2025
www.authorea.com www.authorea.com

Artesunate mitigates acute pancreatitis by enhancing acinar zymophagy via modulating the NRF2-p62-Keap1 loop

1
1. scibot 15 Aug 2025
  
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  DOI: 10.22541/au.175404080.04917407/v1
  
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authorea.com/users/951840/articles/1321154-artesunate-mitigates-acute-pancreatitis-by-enhancing-acinar-zymophagy-via-modulating-the-nrf2-p62-keap1-loop
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autophagy

1
1. scibot 12 Aug 2025
  
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  DOI: 10.1038/s41467-025-62379-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12335601/
Jul 2025
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Increased burden of rare risk variants across gene expression networks predisposes to sporadic Parkinson’s disease

1
1. scibot 16 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.115636
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12258067/
Jun 2025
www.tandfonline.com www.tandfonline.com

Heat-shock chaperone HSPB1 mitigates poly-glycine-induced neurodegeneration via restoration of autophagic flux

1
1. scibot 28 Jun 2025
  
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  DOI: 10.1080/15548627.2025.2466144
  
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tandfonline.com/doi/abs/10.1080/15548627.2025.2466144
52.53.155.43 52.53.155.43

1-s2.0-S2589004225012350-main-html.html

1
1. scibot 21 Jun 2025
  
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  AB_945626
  
  DOI: 10.1016/j.isci.2025.112974
  
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52.53.155.43/228d953e40f5f86c117ef6fb37cbe8e1321da898/1-s2.0-S2589004225012350-main-html.html
May 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225008983-main-html.html

1
1. scibot 18 May 2025
  
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  DOI: 10.1016/j.isci.2025.112637
  
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52.53.155.43/6b559eaf1ba237e9261e221105645573c7e60c53/1-s2.0-S2589004225008983-main-html.html
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SLC7A11 is an unconventional H+ transporter in lysosomes

1
1. scibot 16 May 2025
  
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  DOI: 10.1016/j.cell.2025.04.004
  
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sciencedirect.com/science/article/pii/S0092867425004064
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Sub-Immunosuppressive Tacrolimus Ameliorates Amyloid-Beta and Tau Pathology in 3xTg-AD Mice

1
1. scibot 14 Mar 2025
  
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  DOI: 10.3390/ijms26051797
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11898583/
Feb 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225002731-main-html.html

1
1. scibot 14 Feb 2025
  
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  DOI: 10.1016/j.isci.2025.112013
  
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52.53.155.43/a8a5e839886663f65ab6711a2552cfdbd2c7de90/1-s2.0-S2589004225002731-main-html.html
52.53.155.43 52.53.155.43

Dynamic regulation of the oxidative stress response by the E3 ligase TRIP12

1
1. scibot 07 Feb 2025
  
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  DOI: 10.1101/2024.11.25.625235
  
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52.53.155.43/a7ca056b00d74853454bbdd4617f42c52e9cd355/2024.11.25.625235.full-html.html
52.53.155.43 52.53.155.43

Lysosomal LRRC8 complex regulates lysosomal pH, morphology and systemic glucose metabolism

1
1. scibot 06 Feb 2025
  
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  DOI: 10.1101/2024.09.22.614256
  
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52.53.155.43/17ba4619add80e0a0ad5b6123d474628a07b56f8/2024.09.22.614256.full-html.html
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

An Autophagy-Targeting Chimera Induces Degradation of Androgen Receptor Mutants and AR-v7 in Castration-Resistant Prostate Cancer

1
1. scibot 25 Jan 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-0591
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11733533/
onlinelibrary.wiley.com onlinelibrary.wiley.com

Calcium level and autophagy defect in GNE mutants of rare neuromuscular disorder

1
1. scibot 04 Jan 2025
  
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  DOI: 10.1002/cbin.12268
  
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onlinelibrary.wiley.com/doi/10.1002/cbin.12268
link.springer.com link.springer.com

Alterations of synaptic plasticity and brain oscillation are associated with autophagy induced synaptic pruning during adolescence

1
1. scibot 03 Jan 2025
  
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  DOI: 10.1007/s11571-024-10185-y
  
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link.springer.com/article/10.1007/s11571-024-10185-y
Aug 2024
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Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence

1
1. scibot 23 Aug 2024
  
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  DOI: 10.1016/j.molcel.2024.08.006
  
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sciencedirect.com/science/article/pii/S1097276524006609
www.mdpi.com www.mdpi.com

Ellagic Acid Prevents α-Synuclein Aggregation and Protects SH-SY5Y Cells from Aggregated α-Synuclein-Induced Toxicity via Suppression of Apoptosis and Activation of Autophagy

1
1. scibot 02 Aug 2024
  
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  DOI: 10.3390/ijms222413398
  
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mdpi.com/1422-0067/22/24/13398/htm
onlinelibrary.wiley.com onlinelibrary.wiley.com

Lithium improves cell viability in psychosine‐treated MO3.13 human oligodendrocyte cell line via autophagy activation

2
1. scibot 02 Aug 2024
  
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  DOI: 10.1002/jnr.23910
  
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2. scibot 02 Aug 2024
  
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  AB_945626
  
  DOI: 10.1002/jnr.23910
  
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onlinelibrary.wiley.com/doi/10.1002/jnr.23910/full
Jul 2024
www.cell.com www.cell.com

Adaptation to an acid microenvironment promotes pancreatic cancer organoid growth and drug resistance

1
1. scibot 18 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114409
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00738-1
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The identification of high-performing antibodies for Sequestosome-1 for use in Western blot, immunoprecipitation and immunofluorescence

1
1. scibot 17 Jul 2024
  
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  DOI: 10.12688/f1000research.132628.2
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11240082/
elifesciences.org elifesciences.org

Novel autophagy inducers by accelerating lysosomal clustering against Parkinson’s disease

1
1. scibot 04 Jul 2024
  
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  RRID:AB_945626
  
  DOI: 10.7554/eLife.98649
  
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elifesciences.org/articles/98649
Jun 2024
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Identifying FUS amyotrophic lateral sclerosis disease signatures in patient dermal fibroblasts

1
1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.devcel.2024.05.011
  
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sciencedirect.com/science/article/pii/S1534580724003289
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Multiomic ALS signatures highlight subclusters and sex differences suggesting the MAPK pathway as therapeutic target

1
1. scibot 13 Jun 2024
  
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  DOI: 10.1038/s41467-024-49196-y
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11161513/
May 2024
www.sciencedirect.com www.sciencedirect.com

Pain hypersensitivity is dependent on autophagy protein Beclin 1 in males but not females

1
1. scibot 30 May 2024
  
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  RRID: AB_945626
  
  DOI: 10.1016/j.celrep.2024.114293
  
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sciencedirect.com/science/article/pii/S2211124724006211
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

KAT8 compound inhibition inhibits the initial steps of PINK1-dependant mitophagy

1
1. scibot 25 May 2024
  
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  DOI: 10.1038/s41598-024-60602-9
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11111795/
Apr 2024
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Truncating NFKB1 variants cause combined NLRP3 inflammasome activation and type I interferon signaling and predispose to necrotizing fasciitis

2
1. scibot 09 Apr 2024
  
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  DOI: 10.1016/j.xcrm.2024.101503
  
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2. scibot 09 Apr 2024
  
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  AB_945626
  
  DOI: 10.1016/j.xcrm.2024.101503
  
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sciencedirect.com/science/article/pii/S2666379124001721
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Deficient tRNA posttranscription modification dysregulated the mitochondrial quality controls and apoptosis

1
1. scibot 08 Feb 2024
  
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  RRID:AB_945626
  
  DOI: 10.1016/j.isci.2024.108883
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10838789/
Dec 2023
www.sciencedirect.com www.sciencedirect.com

D-Mannose reduces cellular senescence and NLRP3/GasderminD/IL-1β-driven pyroptotic uroepithelial cell shedding in the murine bladder

1
1. scibot 16 Dec 2023
  
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  RRID:AB_945626
  
  DOI: 10.1016/j.devcel.2023.11.017
  
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sciencedirect.com/science/article/pii/S1534580723006159
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Molecular determinants of the crosstalk between endosomal microautophagy and chaperone-mediated autophagy

1
1. scibot 07 Dec 2023
  
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  RRID:AB_945626
  
  DOI: 10.1016/j.celrep.2023.113529
  
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sciencedirect.com/science/article/pii/S2211124723015413
Nov 2023
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The yeast protein Ure2p triggers Tau pathology in a mouse model of tauopathy

1
1. scibot 02 Nov 2023
  
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  RRID:AB_945626
  
  DOI: 10.1016/j.celrep.2023.113342
  
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sciencedirect.com/science/article/pii/S2211124723013542
Oct 2023
www.sciencedirect.com www.sciencedirect.com

ApoE4-dependent lysosomal cholesterol accumulation impairs mitochondrial homeostasis and oxidative phosphorylation in human astrocytes

1
1. scibot 06 Oct 2023
  
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  RRID:AB_945626
  
  DOI: 10.1016/j.celrep.2023.113183
  
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The Designer Drug αPHP Affected Cell Proliferation and Triggered Deathly Mechanisms in Murine Neural Stem/Progenitor Cells

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Damaged mitochondria recruit the effector NEMO to activate NF-κB signaling

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RhoB Promotes Salmonella survival by Regulating Autophagy

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MARCH7-mediated ubiquitination decreases the solubility of ATG14 to inhibit autophagy

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Bexarotene improves motor function after spinal cord injury in mice

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A mitochondrial iron-responsive pathway regulated by DELE1

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The identification of high-performing antibodies for Sequestosome-1 for use in Western blot, immunoprecipitation and immunofluorescence

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Apr 2023
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RhoB promotes Salmonella survival by regulating autophagy

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Nutrient-sensing AgRP neurons relay control of liver autophagy during energy deprivation

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Determination of the autophagic flux in murine and human peripheral blood mononuclear cells

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The selective autophagy adaptor p62/SQSTM1 forms phase condensates regulated by HSP27 that facilitate the clearance of damaged lysosomes via lysophagy

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FUS ALS neurons activate major stress pathways and reduce translation as an early protective mechanism against neurodegeneration

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Huntingtin exon 1 deletion does not alter the subcellular distribution of huntingtin and gene transcription in mice

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C9orf72 functions in the nucleus to regulate DNA damage repair

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Lack of COL6/collagen VI causes megakaryocyte dysfunction by impairing autophagy and inducing apoptosis

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Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer

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CCT2 is an aggrephagy receptor for clearance of solid protein aggregates

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Pegylated arginine deiminase drives arginine turnover and systemic autophagy to dictate energy metabolism

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Mosaic dysfunction of mitophagy in mitochondrial muscle disease

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BPS Publications

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Chronic lithium administration in a mouse model for Krabbe disease

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CD4+ T cell-mimicking nanoparticles encapsulating DIABLO/SMAC mimetics broadly neutralize HIV-1 and selectively kill HIV-1-infected cells

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Prolyl oligopeptidase inhibition reduces alpha-synuclein aggregation in a cellular model of multiple system atrophy

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Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease

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ER – lysosome contacts at a pre-axonal region regulate axonal lysosome availability

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Human Immunodeficiency Virus Type-1 single-stranded RNA activates the NLRP3 inflammasome and impairs autophagic clearance of damaged mitochondria in human microglia

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Untitled document

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Untitled document

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Untitled document

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Plasma Rich in Growth Factors Promotes Autophagy in ARPE19 Cells in Response to Oxidative Stress Induced by Blue Light

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Lithium improves cell viability in psychosine‐treated MO3.13 human oligodendrocyte cell line via autophagy activation

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Jul 2021
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Negative Regulator of Ubiquitin-Like Protein 1 modulates the autophagy-lysosomal pathway via p62 to facilitate the extracellular release of tau following proteasome impairment

1
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Tanshinone IIA Restores Dynamic Balance of Autophagosome/Autolysosome in Doxorubicin-Induced Cardiotoxicity via Targeting Beclin1/LAMP1

1
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Hypoexcitability precedes denervation in the large fast-contracting motor units in two unrelated mouse models of ALS

1
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Degradation of lipid droplets by chimeric autophagy-tethering compounds

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Jun 2021
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Impact of differential and time-dependent autophagy activation on therapeutic efficacy in a model of Huntington disease

2
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  DOI: 10.1080/15548627.2020.1760014
  
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In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration

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In situ architecture of neuronal α-Synuclein inclusions

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SETD2 mutation in renal clear cell carcinoma suppress autophagy via regulation of ATG12

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Inhibition of p38 Mitogen–Activated Protein Kinase Ameliorates HAP40 Depletion–Induced Toxicity and Proteasomal Defect in Huntington’s Disease Model

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The Deubiquitinating Enzyme Ataxin-3 Regulates Ciliogenesis and Phagocytosis in the Retina

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Gene therapy with secreted acid alpha-glucosidase rescues Pompe disease in a novel mouse model with early-onset spinal cord and respiratory defects

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CD4+ T Cell-Mimicking Nanoparticles Broadly Neutralize HIV-1 and Suppress Viral Replication through Autophagy

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Alpha-lipoic acid protects against pressure overload-induced heart failure via ALDH2-dependent Nrf1-FUNDC1 signaling

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The GTPase Rab27b regulates the release, autophagic clearance, and toxicity of alpha-synuclein

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The UPR preserves mature oligodendrocyte viability and function in adults by regulating autophagy of PLP

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The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice

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Impairment of Macroautophagy in Dopamine Neurons Has Opposing Effects on Parkinsonian Pathology and Behavior

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Stem cell-derived cranial and spinal motor neurons reveal proteostatic differences between ALS resistant and sensitive motor neurons

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The N-Degron Pathway Mediates ER-phagy

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Expression of WIPI2B counteracts age-related decline in autophagosome biogenesis in neurons

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Huntington’s Disease Pathogenesis Is Modified In Vivo by Alfy/Wdfy3 and Selective Macroautophagy

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Chronic optogenetic induction of stress granules is cytotoxic and reveals the evolution of ALS-FTD pathology

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Cardiolipin-Dependent Mitophagy Guides Outcome after Traumatic Brain Injury

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  DOI: 10.1523/JNEUROSCI.3415-17.2018
  
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Complement Component C3 Is Highly Expressed in Human Pancreatic Islets and Prevents β Cell Death via ATG16L1 Interaction and Autophagy Regulation

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Lasting pathologic complete response to chemotherapy for ovarian cancer after receiving antimalarials for dermatomyositis

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Lack of Parkin Anticipates the Phenotype and Affects Mitochondrial Morphology and mtDNA Levels in a Mouse Model of Parkinson's Disease

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Suppression of MAPK11 or HIPK3 reduces mutant Huntingtin levels in Huntington's disease models.

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YOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-κB

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Protandim Protects Oligodendrocytes against an Oxidative Insult

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