116 Matching Annotations
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    Integrative analysis of drug-gene signatures in human pluripotent stem cells reveals prazosin as a novel SQSTM1 regulator for ALS therapeutics
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  3. Jun 2026
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    TRIM21 induces selective autophagy of viruses and bacteria
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  5. May 2026
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    Electroacupuncture (EA) promotes angiogenesis and ameliorates dysregulated autophagy in ischemic stroke mice by modulating the ELAVL1/SIRT1/FOXO1 pathway
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    Wasteosomes (corpora amylacea) of the human brain accumulate in CD44-positive astrocytes
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    A novel recombinant peptide, RGD-Latcripin-7A, targeting neovascularization in skin transplantation: Tissue regeneration and autophagy mechanism
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  9. Jan 2026
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    Myomaker and ether lipids cooperate to promote fusion-competent membrane states
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    Calcium overload induced mitochondrial and lysosomal dysfunction is regulated by Tousled-like kinase in a-synucleinopathy
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    LncRNA DANCR Activates p38/mTOR‐Mediated Autophagy via ANXA2 to Exacerbate Oxygen‐Induced Retinal Neovascularization in Mice
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  13. Dec 2025
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    Pathogenic podocin variants exhibit distinct defects in trafficking, membrane organization, and degradation pathways
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    Sex does not Influence Neuronal Autophagosome Biogenesis throughout Aging in Mice
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    A cancer-specific antigen drives histone acetylation by stabilizing the acetyltransferases
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    Dynamic regulation of the oxidative stress response by the E3 ligase TRIP12
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    Coxsackievirus B infection invokes unique cell-type-specific responses in primary human pancreatic islets
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  22. Aug 2025
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    Artesunate mitigates acute pancreatitis by enhancing acinar zymophagy via modulating the NRF2-p62-Keap1 loop
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  25. Jul 2025
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    Increased burden of rare risk variants across gene expression networks predisposes to sporadic Parkinson’s disease
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  27. Jun 2025
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    Heat-shock chaperone HSPB1 mitigates poly-glycine-induced neurodegeneration via restoration of autophagic flux
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    SLC7A11 is an unconventional H+ transporter in lysosomes
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  33. Mar 2025
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    Sub-Immunosuppressive Tacrolimus Ameliorates Amyloid-Beta and Tau Pathology in 3xTg-AD Mice
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    Lysosomal LRRC8 complex regulates lysosomal pH, morphology and systemic glucose metabolism
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  39. Jan 2025
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    An Autophagy-Targeting Chimera Induces Degradation of Androgen Receptor Mutants and AR-v7 in Castration-Resistant Prostate Cancer
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    Calcium level and autophagy defect in GNE mutants of rare neuromuscular disorder
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    Alterations of synaptic plasticity and brain oscillation are associated with autophagy induced synaptic pruning during adolescence
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  43. Aug 2024
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    Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence
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    Ellagic Acid Prevents α-Synuclein Aggregation and Protects SH-SY5Y Cells from Aggregated α-Synuclein-Induced Toxicity via Suppression of Apoptosis and Activation of Autophagy
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    Lithium improves cell viability in psychosine‐treated MO3.13 human oligodendrocyte cell line via autophagy activation
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    The identification of high-performing antibodies for Sequestosome-1 for use in Western blot, immunoprecipitation and immunofluorescence
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    Novel autophagy inducers by accelerating lysosomal clustering against Parkinson’s disease
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  51. Jun 2024
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    Identifying FUS amyotrophic lateral sclerosis disease signatures in patient dermal fibroblasts
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    Multiomic ALS signatures highlight subclusters and sex differences suggesting the MAPK pathway as therapeutic target
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  54. May 2024
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    Pain hypersensitivity is dependent on autophagy protein Beclin 1 in males but not females
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  57. Apr 2024
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    Truncating NFKB1 variants cause combined NLRP3 inflammasome activation and type I interferon signaling and predispose to necrotizing fasciitis
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    Deficient tRNA posttranscription modification dysregulated the mitochondrial quality controls and apoptosis
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  61. Dec 2023
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    D-Mannose reduces cellular senescence and NLRP3/GasderminD/IL-1β-driven pyroptotic uroepithelial cell shedding in the murine bladder
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    Molecular determinants of the crosstalk between endosomal microautophagy and chaperone-mediated autophagy
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  64. Nov 2023
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    The yeast protein Ure2p triggers Tau pathology in a mouse model of tauopathy
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  66. Oct 2023
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    ApoE4-dependent lysosomal cholesterol accumulation impairs mitochondrial homeostasis and oxidative phosphorylation in human astrocytes
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    The Designer Drug αPHP Affected Cell Proliferation and Triggered Deathly Mechanisms in Murine Neural Stem/Progenitor Cells
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    Damaged mitochondria recruit the effector NEMO to activate NF-κB signaling
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  71. Aug 2023
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    RhoB Promotes Salmonella survival by Regulating Autophagy
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    MARCH7-mediated ubiquitination decreases the solubility of ATG14 to inhibit autophagy
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  74. Jul 2023
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  76. Jun 2023
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    A mitochondrial iron-responsive pathway regulated by DELE1
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  79. Apr 2023
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    RhoB promotes Salmonella survival by regulating autophagy
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    Determination of the autophagic flux in murine and human peripheral blood mononuclear cells
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  83. Jan 2023
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    The selective autophagy adaptor p62/SQSTM1 forms phase condensates regulated by HSP27 that facilitate the clearance of damaged lysosomes via lysophagy
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    FUS ALS neurons activate major stress pathways and reduce translation as an early protective mechanism against neurodegeneration
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  86. Dec 2022
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    Huntingtin exon 1 deletion does not alter the subcellular distribution of huntingtin and gene transcription in mice
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  88. Oct 2022
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    C9orf72 functions in the nucleus to regulate DNA damage repair
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  90. Sep 2022
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    Lack of COL6/collagen VI causes megakaryocyte dysfunction by impairing autophagy and inducing apoptosis
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  92. May 2022
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    Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer
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    CCT2 is an aggrephagy receptor for clearance of solid protein aggregates
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  96. Jan 2022
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    Pegylated arginine deiminase drives arginine turnover and systemic autophagy to dictate energy metabolism
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    Mosaic dysfunction of mitophagy in mitochondrial muscle disease
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  99. Dec 2021
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  101. Nov 2021
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    Chronic lithium administration in a mouse model for Krabbe disease
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  103. Sep 2021
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    CD4+ T cell-mimicking nanoparticles encapsulating DIABLO/SMAC mimetics broadly neutralize HIV-1 and selectively kill HIV-1-infected cells
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    Prolyl oligopeptidase inhibition reduces alpha-synuclein aggregation in a cellular model of multiple system atrophy
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    Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease
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  107. Aug 2021
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ER – lysosome contacts at a pre-axonal region regulate axonal lysosome availability
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    Human Immunodeficiency Virus Type-1 single-stranded RNA activates the NLRP3 inflammasome and impairs autophagic clearance of damaged mitochondria in human microglia
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  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Plasma Rich in Growth Factors Promotes Autophagy in ARPE19 Cells in Response to Oxidative Stress Induced by Blue Light
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    Lithium improves cell viability in psychosine‐treated MO3.13 human oligodendrocyte cell line via autophagy activation
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  115. Jul 2021
  116. academic.oup.com academic.oup.com
    Negative Regulator of Ubiquitin-Like Protein 1 modulates the autophagy-lysosomal pathway via p62 to facilitate the extracellular release of tau following proteasome impairment
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    academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddz255/5613690
  117. www.mdpi.com www.mdpi.com
    Tanshinone IIA Restores Dynamic Balance of Autophagosome/Autolysosome in Doxorubicin-Induced Cardiotoxicity via Targeting Beclin1/LAMP1
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    Hypoexcitability precedes denervation in the large fast-contracting motor units in two unrelated mouse models of ALS
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    Degradation of lipid droplets by chimeric autophagy-tethering compounds
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  120. Jun 2021
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    Impact of differential and time-dependent autophagy activation on therapeutic efficacy in a model of Huntington disease
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  122. May 2021
  123. link.springer.com link.springer.com
    In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration
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