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Thwarting of Lphn3 Functions in Cell Motility and Signaling by Cancer-Related GAIN Domain Somatic Mutations

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1. scibot 19 Sep 2026
  
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  DOI: 10.3390/cells11121913
  
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pmc.ncbi.nlm.nih.gov/articles/PMC9221416/
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Regulation of MRGPRX2-mediated mast cell function by competence-stimulating peptide 1 and pro-adrenomedullin peptide

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1. scibot 19 Sep 2026
  
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  DOI: 10.3389/fimmu.2026.1781889
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13035742/
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Regulation of CXCR4 function by S1P1 through heteromerization

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1. scibot 19 Sep 2026
  
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  DOI: 10.1186/s12964-025-02099-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11863771/
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Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1

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1. scibot 19 Sep 2026
  
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  DOI: 10.1038/s41586-022-04580-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC9046087/
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Gαq activation of free fatty acid receptor 4 suppresses metabolic dysfunction by disrupting Nr1h3-PPARγ axis

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1. scibot 19 Sep 2026
  
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  DOI: 10.1038/s41467-026-75589-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13490442/
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Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design

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1. scibot 19 Sep 2026
  
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  DOI: 10.1038/s41467-021-25020-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC8342441/
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Structural insights into dimerization and activation of the mGlu2–mGlu3 and mGlu2–mGlu4 heterodimers

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1. scibot 19 Sep 2026
  
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  DOI: 10.1038/s41422-023-00830-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10543438/
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Next-generation chemogenetic inhibition using a brain-permeant non-prescription agent

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1. scibot 19 Sep 2026
  
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  DOI: 10.1038/s41392-026-02865-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13328383/
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Synthesis and Pharmacology of a Morphinan-Derived Dual Mu–Kappa Opioid Receptor Agonist Analgesic

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1. scibot 19 Sep 2026
  
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  DOI: 10.1021/acschemneuro.5c00312
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12288146/
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GRK phosphorylation drives β-arrestin–independent internalization of chemokine receptor CXCR5

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1. scibot 19 Sep 2026
  
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  DOI: 10.1016/j.jbc.2025.111114
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12859505/
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Receptor activity–modifying protein 3 enhances GLP-1-mediated insulin secretion

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1. scibot 19 Sep 2026
  
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  DOI: 10.1016/j.jbc.2025.110604
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12624773/
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GLP-1 metabolite GLP-1(9–36) is a systemic inhibitor of mouse and human pancreatic islet glucagon secretion

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1. scibot 19 Sep 2026
  
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  1000000163
  
  DOI: 10.1007/s00125-023-06060-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10844371/
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An ionic lock and a hydrophobic zipper mediate the coupling between an insect pheromone receptor BmOR3 and downstream effectors

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1. scibot 18 Sep 2026
  
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  DOI: 10.1016/j.jbc.2021.101160
  
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pmc.ncbi.nlm.nih.gov/articles/PMC8477192/
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Molecular insights into the regulation of constitutive activity by RNA editing of 5HT2C serotonin receptors

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1. scibot 18 Sep 2026
  
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  1000000163
  
  DOI: 10.1016/j.celrep.2022.111211
  
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pmc.ncbi.nlm.nih.gov/articles/PMC9422347/
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Discovery and dynamic pharmacology of μ-opioid receptor positive allosteric modulators

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1. scibot 17 Sep 2026
  
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  1000000163
  
  DOI: 10.64898/2026.02.20.707058
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12934670/
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Novel Pharmacology Following Heteromerization of the Angiotensin II Type 2 Receptor and the Bradykinin Type 2 Receptor

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1. scibot 17 Sep 2026
  
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  1000000163
  
  DOI: 10.3389/fendo.2022.848816
  
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pmc.ncbi.nlm.nih.gov/articles/PMC9204302/
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Receptor Activity-Modifying Protein 3 enhances GLP-1-mediated Insulin Secretion

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1. scibot 17 Sep 2026
  
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  1000000163
  
  DOI: 10.1101/2025.01.24.634724
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12363685/
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Crystal structure of adenosine A2A receptor in complex with clinical candidate Etrumadenant reveals unprecedented antagonist interaction

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1. scibot 17 Sep 2026
  
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  1000000163
  
  DOI: 10.1038/s42004-023-00894-6
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10235125/
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Structural Insights into Partial Activation of the Prototypic G Protein-Coupled Adenosine A2A Receptor

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1. scibot 17 Sep 2026
  
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  DOI: 10.1021/acsptsci.4c00051
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11091970/
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Agonist-Dependent Coupling of the Promiscuous Adenosine A2B Receptor to Gα Protein Subunits

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1. scibot 17 Sep 2026
  
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  DOI: 10.1021/acsptsci.2c00020
  
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pmc.ncbi.nlm.nih.gov/articles/PMC9112290/
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Molecular insights into ligand recognition and receptor activation of GPR15

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1. scibot 17 Sep 2026
  
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  1000000163
  
  DOI: 10.1016/j.isci.2025.113935
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12663730/
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Ligand-directed bias of G protein signaling at the dopamine D2 receptor

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1. scibot 17 Sep 2026
  
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  DOI: 10.1016/j.chembiol.2021.07.004
  
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pmc.ncbi.nlm.nih.gov/articles/PMC8770702/
Sep 2026
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Advancements in GPCR biosensors to study GPCR-G Protein coupling

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1. scibot 16 Sep 2026
  
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  DOI: 10.1111/bph.15962
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10511148/
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Designing allosteric modulators to change GPCR G protein subtype selectivity

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1. scibot 15 Sep 2026
  
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  DOI: 10.1038/s41586-025-09643-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12675282/
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Structural basis for ligand promiscuity and high signaling activity of Kaposi’s Sarcoma-associated Herpesvirus-encoded GPCR

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1. scibot 15 Sep 2026
  
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  DOI: 10.1038/s41467-025-63457-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12462484/
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Semi‐synthetic nanobody‐ligand conjugates exhibit tunable signaling properties and enhanced transcriptional outputs at neurokinin receptor‐1

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1. scibot 15 Sep 2026
  
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  DOI: 10.1002/pro.4866
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10806929/
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Design of allosteric modulators that change GPCR G protein subtype selectivity

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1. scibot 12 Sep 2026
  
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  DOI: 10.21203/rs.3.rs-5538058/v1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11661308/
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Design of allosteric modulators that change GPCR G protein subtype selectivity

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1. scibot 12 Sep 2026
  
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  DOI: 10.1101/2024.11.20.624209
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11601581/
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Semi-synthetic nanobody-ligand conjugates exhibit tunable signaling properties and enhanced transcriptional outputs at neurokinin receptor-1

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1. scibot 12 Sep 2026
  
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  1000000163
  
  DOI: 10.1101/2023.10.08.561411
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10659424/