Hypothesis

15 Matching Annotations

Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Mechanism of expression regulation of head-to-head overlapping protein-coding genes INO80E and HIRIP3

2
1. scibot 23 Mar 2025
  
  in Public
  
  pEGFP-RNASEH1
  
  DOI: 10.1038/s42003-025-07815-4
  
  Resource: RRID:Addgene_108699
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_108699
  
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  RRID:Addgene_108699
2. scibot 11 Mar 2025
  
  in Public
  
  RRID:Addgene_108699
  
  DOI: 10.1038/s42003-025-07815-4
  
  Resource: RRID:Addgene_108699
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_108699
  
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  RRID:Addgene_108699
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RRID:Addgene_108699

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pmc.ncbi.nlm.nih.gov/articles/PMC11890862/
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Senataxin deficiency disrupts proteostasis through nucleolar ncRNA-driven protein aggregation

1
1. scibot 10 Nov 2024
  
  in Public
  
  plasmid_108699
  
  DOI: 10.1083/jcb.202309036
  
  Resource: RRID:Addgene_108699
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_108699
  
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  RRID:Addgene_108699
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RRID:Addgene_108699

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC11080644/
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

AKT1 interacts with DHX9 to mitigate R-loop-induced replication stress in ovarian cancer

1
1. scibot 25 Sep 2024
  
  in Public
  
  108699
  
  DOI: 10.1158/0008-5472.CAN-23-1908
  
  Resource: RRID:Addgene_108699
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_108699
  
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  RRID:Addgene_108699
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RRID:Addgene_108699

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scibot

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ncbi.nlm.nih.gov/pmc/articles/PMC10947874/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

R-loops and impaired autophagy trigger cGAS-dependent inflammation via micronuclei formation in Senataxin-deficient cells

1
1. scibot 23 Aug 2024
  
  in Public
  
  RRID:Addgene_108699
  
  DOI: 10.1007/s00018-024-05380-3
  
  Resource: RRID:Addgene_108699
  
  Curator: @scibot
  
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  RRID:Addgene_108699
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ncbi.nlm.nih.gov/pmc/articles/PMC11335261/
Feb 2024
www.biorxiv.org www.biorxiv.org

5’ extended protein-coding INO80E transcript regulates expression of two head-to-head overlapping genes: INO80E and HIRIP3

1
1. scibot 09 Feb 2024
  
  in Public
  
  RRID:Addgene_108699
  
  DOI: 10.1101/2023.12.04.569901
  
  Resource: RRID:Addgene_108699
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_108699
  
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  RRID:Addgene_108699
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biorxiv.org/content/10.1101/2023.12.04.569901v1
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PSIP1/LEDGF reduces R-loops at transcription sites to maintain genome integrity

1
1. scibot 08 Feb 2024
  
  in Public
  
  108699
  
  DOI: 10.1038/s41467-023-44544-w
  
  Resource: RRID:Addgene_108699
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_108699
  
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  RRID:Addgene_108699
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ncbi.nlm.nih.gov/pmc/articles/PMC10774266/
Nov 2023
dx.doi.org dx.doi.org

Reactivation of the G1 enhancer landscape underlies core circuitry addiction to SWI/SNF

1
1. scibot 26 Nov 2023
  
  in Public
  
  RRID:Addgene_108699
  
  DOI: 10.1093/nar/gkad1081
  
  Resource: RRID:Addgene_108699
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_108699
  
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  RRID:Addgene_108699
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dx.doi.org/10.1093/nar/gkad1081
Jul 2023
www.sciencedirect.com www.sciencedirect.com

MEF2A suppresses stress responses that trigger DDX41-dependent IFN production

1
1. scibot 21 Jul 2023
  
  in Public
  
  plasmid_108699
  
  DOI: 10.1016/j.celrep.2023.112805
  
  Resource: RRID:Addgene_108699
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_108699
  
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  RRID:Addgene_108699
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RRID:Addgene_108699

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sciencedirect.com/science/article/pii/S2211124723008161
Sep 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CANCER-ASSOCIATED SF3B1 MUTATIONS CONFER A BRCA-LIKE CELLULAR PHENOTYPE AND SYNTHETIC LETHALITY TO PARP INHIBITORS

1
1. scibot 02 Sep 2022
  
  in Public
  
  RRID:Addgene_108699
  
  DOI: 10.1158/0008-5472.CAN-21-1843
  
  Resource: RRID:Addgene_108699
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_108699
  
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  RRID:Addgene_108699
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ncbi.nlm.nih.gov/pmc/articles/PMC7612475/
Jun 2022
www.sciencedirect.com www.sciencedirect.com

Counteracting chromatin effects of a splicing-correcting antisense oligonucleotide improves its therapeutic efficacy in spinal muscular atrophy

1
1. scibot 10 Jun 2022
  
  in Public
  
  Addgene, cat.# 108699
  
  DOI: 10.1016/j.cell.2022.04.031
  
  Resource: RRID:Addgene_108699
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:Addgene_108699
  
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  RRID:Addgene_108699
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sciencedirect.com/science/article/pii/S0092867422005293
Dec 2021
genomebiology.biomedcentral.com genomebiology.biomedcentral.com

Programmed genomic instability regulates neural transdifferentiation of human brain microvascular pericytes

1
1. scibot 11 Dec 2021
  
  in Public
  
  RRID:s:Addgene_108699
  
  DOI: 10.1186/s13059-021-02555-0
  
  Resource: RRID:Addgene_108699
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_108699
  
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  RRID:Addgene_108699 RRIDCUR:Unresolved RRIDCUR:SyntaxError
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RRIDCUR:SyntaxError

RRIDCUR:Unresolved

RRID:Addgene_108699

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scibot

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genomebiology.biomedcentral.com/articles/10.1186/s13059-021-02555-0
Mar 2021
www.sciencedirect.com www.sciencedirect.com

A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome Instability

1
1. scibot 03 Mar 2021
  
  in Public
  
  Addgene_108699
  
  DOI: 10.1016/j.celrep.2020.01.020
  
  Resource: RRID:Addgene_108699
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_108699
  
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  RRID:Addgene_108699 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:Addgene_108699

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scibot

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sciencedirect.com/science/article/pii/S2211124720300292
Feb 2021
www.sciencedirect.com www.sciencedirect.com

A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome Instability

1
1. scibot 24 Feb 2021
  
  in Public
  
  Addgene_108699
  
  DOI: 10.1016/j.celrep.2020.01.020
  
  Resource: RRID:Addgene_108699
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_108699
  
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  RRID:Addgene_108699
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sciencedirect.com/science/article/pii/S2211124720300292
Sep 2020
www.nature.com www.nature.com

N 6 -methyladenosine regulates the stability of RNA:DNA hybrids in human cells

1
1. scibot 08 Sep 2020
  
  in Public
  
  RRID:Addgene_108699
  
  DOI: 10.1038/s41588-019-0549-x
  
  Resource: RRID:Addgene_108699
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_108699
  
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  RRID:Addgene_108699 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:Addgene_108699

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scibot

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nature.com/articles/s41588-019-0549-x