46 Matching Annotations
  1. Aug 2025
  2. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225017006-main-html.html
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    52.53.155.43/4445811476685d53e8e368f4c93f2019d1647905/1-s2.0-S2589004225017006-main-html.html
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NAMPT and NNMT released via extracellular vesicles and as soluble mediators are distinguished traits of BRAF inhibitor resistance of melanoma cells impacting on the tumor microenvironment
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    pmc.ncbi.nlm.nih.gov/articles/PMC12278642/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of nonsense-mediated decay in TDP-43 deficient neurons reveals novel cryptic exons
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    pmc.ncbi.nlm.nih.gov/articles/PMC12262666/
  5. Jul 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TP53 missense–specific transcriptional plasticity drives resistance against cell cycle inhibitors in pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12227071/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DSG2 promotes pancreatic cancer stem cell maintenance via support of tumour and macrophage cellular cross-talk
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    pmc.ncbi.nlm.nih.gov/articles/PMC12227620/
  8. www.science.org www.science.org
    TP53 missense–specific transcriptional plasticity drives resistance against cell cycle inhibitors in pancreatic cancer
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    science.org/doi/10.1126/sciadv.adu2339
  9. www.nature.com www.nature.com
    Molecular docking and biological evaluation of a novel IWS1 inhibitor for the treatment of human retroperitoneal liposarcoma
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    nature.com/articles/s41598-025-07215-y
  10. Jun 2025
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Genome-Wide Synthetic Lethal Screen Identifies Spermidine Synthase as a Target to Enhance Erdafitinib Efficacy in FGFR-Mutant Bladder Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12167931/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PRPS activity tunes redox homeostasis in Myc-driven lymphoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12166406/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNA shielding of P65 is required to potentiate oncogenic inflammation in TET2 mutated clonal hematopoiesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11611684/
  14. Apr 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Elevated VRK1 levels after androgen deprivation therapy promote prostate cancer progression by upregulating YAP1 expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11926012/
  16. Mar 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    REDD1-dependent GSK3β signaling in podocytes promotes canonical NF-κB activation in diabetic nephropathy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11904504/
  18. www.sciencedirect.com www.sciencedirect.com
    PTPσ-mediated PI3P regulation modulates neurodegeneration in C9ORF72-ALS/FTD
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    sciencedirect.com/science/article/pii/S0896627325001187
  19. Sep 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cysteine-rich with EGF-like domains 2 (CRELD2) is an endoplasmic reticulum stress-inducible angiogenic growth factor promoting ischemic heart repair
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    ncbi.nlm.nih.gov/pmc/articles/PMC11358006/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLC13A3 is a major effector downstream of activated β-catenin in liver cancer pathogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11364541/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic Profiling of Cochlear Organoids Identifies α‐Ketoglutarate and NAD+ as Limiting Factors for Hair Cell Reprogramming
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    ncbi.nlm.nih.gov/pmc/articles/PMC11425867/
  23. www.sciencedirect.com www.sciencedirect.com
    Hydrogen sulfide-mediated persulfidation regulates homocysteine metabolism and enhances ferroptosis in non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S1097276524007317
  24. Aug 2024
  25. www.sciencedirect.com www.sciencedirect.com
    Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence
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    sciencedirect.com/science/article/pii/S1097276524006609
  26. www.nature.com www.nature.com
    Compression-dependent microtubule reinforcement enables cells to navigate confined environments
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    nature.com/articles/s41556-024-01476-x
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRPS2‐mediated modulation of the antitumor immune response in lung cancer through CCL2‐mediated tumor‐associated macrophages and myeloid‐derived suppressor cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11320087/
  28. Jun 2024
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FOXA3 regulates cholesterol metabolism to compensate for low uptake during the progression of lung adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11161053/
  30. May 2024
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumour‐derived exosome SNHG17 induced by oestrogen contributes to ovarian cancer progression via the CCL13–CCR2–M2 macrophage axis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11056704/
  32. Apr 2024
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic targeting of cancer associated fibroblasts overcomes T-cell exclusion and chemoresistance in soft-tissue sarcomas
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    ncbi.nlm.nih.gov/pmc/articles/PMC10954767/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intrinsic and extrinsic actions of human neural progenitors with SUFU inhibition promote tissue repair and functional recovery from severe spinal cord injury
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    ncbi.nlm.nih.gov/pmc/articles/PMC10959923/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NLRP3 Inflammasome Priming in the Retina of Diabetic Mice Requires REDD1-Dependent Activation of GSK3β
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    ncbi.nlm.nih.gov/pmc/articles/PMC10981446/
  36. Mar 2024
  37. www.sciencedirect.com www.sciencedirect.com
    A gut-derived hormone regulates cholesterol metabolism
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    sciencedirect.com/science/article/pii/S0092867424002265
  38. Feb 2024
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cystine deprivation triggers CD36-mediated ferroptosis and dysfunction of tumor infiltrating CD8+ T cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10869360/
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mcam inhibits macrophage-mediated development of mammary gland through non-canonical Wnt signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC10761817/
  41. Jan 2024
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EGFR core fucosylation, induced by hepatitis C virus, promotes TRIM40-mediated-RIG-I ubiquitination and suppresses interferon-I antiviral defenses
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    ncbi.nlm.nih.gov/pmc/articles/PMC10803816/
  43. Oct 2023
  44. www.sciencedirect.com www.sciencedirect.com
    Fibroblast activation protein drives tumor metastasis via a protease-independent role in invadopodia stabilization
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    sciencedirect.com/science/article/pii/S2211124723013141
  45. Sep 2023
  46. www.nature.com www.nature.com
    HERC1 deficiency causes osteopenia through transcriptional program dysregulation during bone remodeling
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    nature.com/articles/s41419-023-05549-x
  47. Aug 2023
  48. www.biorxiv.org www.biorxiv.org
    The endosomal sorting complex Retromer has a central role in systemic cholesterol homeostasis by controlling endo-lysosomal cholesterol transport in hepatocytes
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    biorxiv.org/content/10.1101/2023.08.09.552611v2
  49. Jul 2023
  50. www.sciencedirect.com www.sciencedirect.com
    mRNA stability and m6A are major determinants of subcellular mRNA localization in neurons
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    sciencedirect.com/science/article/pii/S1097276523004689
  51. www.sciencedirect.com www.sciencedirect.com
    REDD1-dependent GSK3β dephosphorylation promotes NF-κB activation and macrophage infiltration in the retina of diabetic mice
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    sciencedirect.com/science/article/pii/S0021925823020197
  52. Feb 2023
  53. www.sciencedirect.com www.sciencedirect.com
    Injury primes mutation-bearing astrocytes for dedifferentiation in later life
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    sciencedirect.com/science/article/pii/S0960982223001525
  54. Jan 2023
  55. www.sciencedirect.com www.sciencedirect.com
    Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy
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    sciencedirect.com/science/article/pii/S1535610822005943
  56. Oct 2022
  57. www.sciencedirect.com www.sciencedirect.com
    Stress response protein REDD1 promotes diabetes-induced retinal inflammation by sustaining canonical NF-κB signaling
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    sciencedirect.com/science/article/pii/S002192582201081X
  58. link.springer.com link.springer.com
    HERC2 deficiency activates C-RAF/MKK3/p38 signalling pathway altering the cellular response to oxidative stress
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    link.springer.com/article/10.1007/s00018-022-04586-7
  59. Jun 2022
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SAMM50 Regulates Thermogenesis of Beige Adipocytes Differentiated from Human Adipose-Derived Stem Cells by Balancing Mitochondrial Dynamics
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    ncbi.nlm.nih.gov/pmc/articles/PMC9224253/
  61. www.sciencedirect.com www.sciencedirect.com
    Single-cell RNA-seq of a soft-tissue sarcoma model reveals the critical role of tumor-expressed MIF in shaping macrophage heterogeneity
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    sciencedirect.com/science/article/pii/S221112472200763X
  62. Jun 2021
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SIRT1 regulates sphingolipid metabolism and neural differentiation of mouse embryonic stem cells through c-Myc-SMPDL3B
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    ncbi.nlm.nih.gov/pmc/articles/PMC8216717/
  64. May 2021
  65. www.sciencedirect.com www.sciencedirect.com
    Repression of endogenous retroviruses prevents antiviral immune response and is required for mammary gland development
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    sciencedirect.com/science/article/pii/S193459092100206X
  66. www.sciencedirect.com www.sciencedirect.com
    The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
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    sciencedirect.com/science/article/pii/S009286742100502X
  67. Sep 2020
  68. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Enhancer RNAs predict enhancer–gene regulatory links and are critical for enhancer function in neuronal systems
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    pubmed.ncbi.nlm.nih.gov/32810208/
  69. Jan 2020
  70. www.sciencedirect.com www.sciencedirect.com
    Mitigating Antagonism between Transcription and Proliferation Allows Near-Deterministic Cellular Reprogramming
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    sciencedirect.com/science/article/pii/S1934590919303406