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Oct 2025
www.biorxiv.org www.biorxiv.org

AGO1 in neural progenitor cells orchestrates brain development and sociability via LIN28A-REELIN axis

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1. scibot 08 Oct 2025
  
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  Addgene 10879
  
  DOI: 10.1101/2025.10.01.679670
  
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biorxiv.org/content/10.1101/2025.10.01.679670v1
Sep 2025
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Mutant RIT1 cooperates with YAP to drive an EMT-like lung cancer state

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1. scibot 25 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116185
  
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sciencedirect.com/science/article/pii/S2211124725009568
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Nucleolar stress facilitates islet β cell senescence via hijacking the DNA damage response pathways

1
1. scibot 23 Sep 2025
  
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  Addgene_10879
  
  DOI: 10.1016/j.isci.2025.113508
  
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sciencedirect.com/science/article/pii/S2589004225017699
Aug 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225017006-main-html.html

1
1. scibot 27 Aug 2025
  
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  RRID:Addgene_108
  
  DOI: 10.1016/j.isci.2025.113439
  
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52.53.155.43/4445811476685d53e8e368f4c93f2019d1647905/1-s2.0-S2589004225017006-main-html.html
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

NAMPT and NNMT released via extracellular vesicles and as soluble mediators are distinguished traits of BRAF inhibitor resistance of melanoma cells impacting on the tumor microenvironment

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1. scibot 11 Aug 2025
  
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  Plasmid_10879
  
  DOI: 10.1186/s12964-025-02361-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12278642/
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Inhibition of nonsense-mediated decay in TDP-43 deficient neurons reveals novel cryptic exons

1
1. scibot 11 Aug 2025
  
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  Addgene_10879
  
  DOI: 10.1101/2025.06.28.661837
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12262666/
Jul 2025
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TP53 missense–specific transcriptional plasticity drives resistance against cell cycle inhibitors in pancreatic cancer

1
1. scibot 20 Jul 2025
  
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  10879
  
  DOI: 10.1126/sciadv.adu2339
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12227071/
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DSG2 promotes pancreatic cancer stem cell maintenance via support of tumour and macrophage cellular cross-talk

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1. scibot 20 Jul 2025
  
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  DOI: 10.1038/s41419-025-07833-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12227620/
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TP53 missense–specific transcriptional plasticity drives resistance against cell cycle inhibitors in pancreatic cancer

1
1. scibot 08 Jul 2025
  
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  no. 10879
  
  DOI: 10.1126/sciadv.adu2339
  
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science.org/doi/10.1126/sciadv.adu2339
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Molecular docking and biological evaluation of a novel IWS1 inhibitor for the treatment of human retroperitoneal liposarcoma

1
1. scibot 03 Jul 2025
  
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  RRID:Addgene_10879
  
  DOI: 10.1038/s41598-025-07215-y
  
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nature.com/articles/s41598-025-07215-y
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A Genome-Wide Synthetic Lethal Screen Identifies Spermidine Synthase as a Target to Enhance Erdafitinib Efficacy in FGFR-Mutant Bladder Cancer

1
1. scibot 18 Jun 2025
  
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  RRID:Addgene_10879
  
  DOI: 10.1158/0008-5472.CAN-24-3217
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12167931/
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PRPS activity tunes redox homeostasis in Myc-driven lymphoma

1
1. scibot 18 Jun 2025
  
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  RRID:Addgene_10879
  
  DOI: 10.1016/j.redox.2025.103649
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12166406/
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RNA shielding of P65 is required to potentiate oncogenic inflammation in TET2 mutated clonal hematopoiesis

1
1. scibot 11 Jun 2025
  
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  RRID:Addgene_10879
  
  DOI: 10.1158/2159-8290.CD-24-0093
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11611684/
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Elevated VRK1 levels after androgen deprivation therapy promote prostate cancer progression by upregulating YAP1 expression

1
1. scibot 07 Apr 2025
  
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  10,879
  
  DOI: 10.1007/s00432-025-06168-z
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11926012/
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

REDD1-dependent GSK3β signaling in podocytes promotes canonical NF-κB activation in diabetic nephropathy

1
1. scibot 23 Mar 2025
  
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  plasmid_10879
  
  DOI: 10.1016/j.jbc.2025.108244
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11904504/
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PTPσ-mediated PI3P regulation modulates neurodegeneration in C9ORF72-ALS/FTD

1
1. scibot 13 Mar 2025
  
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  RRID:Addgene_10879
  
  DOI: 10.1016/j.neuron.2025.02.005
  
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sciencedirect.com/science/article/pii/S0896627325001187
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cysteine-rich with EGF-like domains 2 (CRELD2) is an endoplasmic reticulum stress-inducible angiogenic growth factor promoting ischemic heart repair

1
1. scibot 29 Sep 2024
  
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  10879
  
  DOI: 10.1038/s44161-023-00411-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11358006/
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SLC13A3 is a major effector downstream of activated β-catenin in liver cancer pathogenesis

1
1. scibot 29 Sep 2024
  
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  10879
  
  DOI: 10.1038/s41467-024-51860-2
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11364541/
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Metabolic Profiling of Cochlear Organoids Identifies α‐Ketoglutarate and NAD+ as Limiting Factors for Hair Cell Reprogramming

1
1. scibot 28 Sep 2024
  
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  10879
  
  DOI: 10.1002/advs.202308032
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11425867/
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Hydrogen sulfide-mediated persulfidation regulates homocysteine metabolism and enhances ferroptosis in non-small cell lung cancer

1
1. scibot 25 Sep 2024
  
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  AddgeneCat#10879
  
  DOI: 10.1016/j.molcel.2024.08.035
  
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sciencedirect.com/science/article/pii/S1097276524007317
Aug 2024
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Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence

1
1. scibot 23 Aug 2024
  
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  Addgene_10879
  
  DOI: 10.1016/j.molcel.2024.08.006
  
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sciencedirect.com/science/article/pii/S1097276524006609
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Compression-dependent microtubule reinforcement enables cells to navigate confined environments

1
1. scibot 23 Aug 2024
  
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  RRID:Addgene_10879
  
  DOI: 10.1038/s41556-024-01476-x
  
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nature.com/articles/s41556-024-01476-x
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PRPS2‐mediated modulation of the antitumor immune response in lung cancer through CCL2‐mediated tumor‐associated macrophages and myeloid‐derived suppressor cells

1
1. scibot 17 Aug 2024
  
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  PLKO.1‐TRC
  
  DOI: 10.1111/1759-7714.15398
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11320087/
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

FOXA3 regulates cholesterol metabolism to compensate for low uptake during the progression of lung adenocarcinoma

1
1. scibot 09 Jun 2024
  
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  10879
  
  DOI: 10.1371/journal.pbio.3002621
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11161053/
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Tumour‐derived exosome SNHG17 induced by oestrogen contributes to ovarian cancer progression via the CCL13–CCR2–M2 macrophage axis

1
1. scibot 05 May 2024
  
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  pLKO.1‐TRC
  
  DOI: 10.1111/jcmm.18315
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11056704/
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Metabolic targeting of cancer associated fibroblasts overcomes T-cell exclusion and chemoresistance in soft-tissue sarcomas

1
1. scibot 15 Apr 2024
  
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  Addgene_10879
  
  DOI: 10.1038/s41467-024-46504-4
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10954767/
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Intrinsic and extrinsic actions of human neural progenitors with SUFU inhibition promote tissue repair and functional recovery from severe spinal cord injury

1
1. scibot 15 Apr 2024
  
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  plasmid_10879
  
  DOI: 10.1038/s41536-024-00352-4
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10959923/
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NLRP3 Inflammasome Priming in the Retina of Diabetic Mice Requires REDD1-Dependent Activation of GSK3β

1
1. scibot 01 Apr 2024
  
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  Plasmid_10879
  
  DOI: 10.1167/iovs.65.3.34
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10981446/
Mar 2024
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A gut-derived hormone regulates cholesterol metabolism

2
1. scibot 19 Mar 2024
  
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  RRID:Addgene_10879
  
  DOI: 10.1016/j.cell.2024.02.024
  
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2. scibot 19 Mar 2024
  
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  RRID:Addgene_10879
  
  DOI: 10.1016/j.cell.2024.02.024
  
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sciencedirect.com/science/article/pii/S0092867424002265
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cystine deprivation triggers CD36-mediated ferroptosis and dysfunction of tumor infiltrating CD8+ T cells

1
1. scibot 21 Feb 2024
  
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  10879
  
  DOI: 10.1038/s41419-024-06503-1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10869360/
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Mcam inhibits macrophage-mediated development of mammary gland through non-canonical Wnt signaling

1
1. scibot 13 Feb 2024
  
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  Addgene_10879
  
  DOI: 10.1038/s41467-023-44338-0
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10761817/
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

EGFR core fucosylation, induced by hepatitis C virus, promotes TRIM40-mediated-RIG-I ubiquitination and suppresses interferon-I antiviral defenses

1
1. scibot 30 Jan 2024
  
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  Addgene plasmid Cat# 10879
  
  DOI: 10.1038/s41467-024-44960-6
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10803816/
Oct 2023
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Fibroblast activation protein drives tumor metastasis via a protease-independent role in invadopodia stabilization

1
1. scibot 27 Oct 2023
  
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  plasmid_10879
  
  DOI: 10.1016/j.celrep.2023.113302
  
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sciencedirect.com/science/article/pii/S2211124723013141
Sep 2023
www.nature.com www.nature.com

HERC1 deficiency causes osteopenia through transcriptional program dysregulation during bone remodeling

1
1. scibot 20 Sep 2023
  
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  plasmid_10879
  
  DOI: 10.1038/s41419-023-05549-x
  
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nature.com/articles/s41419-023-05549-x
Aug 2023
www.biorxiv.org www.biorxiv.org

The endosomal sorting complex Retromer has a central role in systemic cholesterol homeostasis by controlling endo-lysosomal cholesterol transport in hepatocytes

1
1. scibot 17 Aug 2023
  
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  RRID:Addgene_10879
  
  DOI: 10.1101/2023.08.09.552611
  
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biorxiv.org/content/10.1101/2023.08.09.552611v2
Jul 2023
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mRNA stability and m6A are major determinants of subcellular mRNA localization in neurons

1
1. scibot 14 Jul 2023
  
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  Addgene_10879
  
  DOI: 10.1016/j.molcel.2023.06.021
  
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sciencedirect.com/science/article/pii/S1097276523004689
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REDD1-dependent GSK3β dephosphorylation promotes NF-κB activation and macrophage infiltration in the retina of diabetic mice

1
1. scibot 05 Jul 2023
  
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  Plasmid_10879
  
  DOI: 10.1016/j.jbc.2023.104991
  
  Resource: RRID:Addgene_10879
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S0021925823020197
Feb 2023
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Injury primes mutation-bearing astrocytes for dedifferentiation in later life

1
1. scibot 25 Feb 2023
  
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  RRID:Addgene_10879
  
  DOI: 10.1016/j.cub.2023.02.013
  
  Resource: RRID:Addgene_10879
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S0960982223001525
Jan 2023
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Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy

1
1. scibot 19 Jan 2023
  
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  Addgene_10879
  
  DOI: 10.1016/j.ccell.2022.12.008
  
  Resource: RRID:Addgene_10879
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1535610822005943
Oct 2022
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Stress response protein REDD1 promotes diabetes-induced retinal inflammation by sustaining canonical NF-κB signaling

1
1. scibot 28 Oct 2022
  
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  Plasmid_10879
  
  DOI: 10.1016/j.jbc.2022.102638
  
  Resource: RRID:Addgene_10879
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S002192582201081X
link.springer.com link.springer.com

HERC2 deficiency activates C-RAF/MKK3/p38 signalling pathway altering the cellular response to oxidative stress

1
1. scibot 15 Oct 2022
  
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  RRID:Addgene_10879
  
  DOI: 10.1007/s00018-022-04586-7
  
  Resource: RRID:Addgene_10879
  
  Curator: @scibot
  
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link.springer.com/article/10.1007/s00018-022-04586-7
Jun 2022
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SAMM50 Regulates Thermogenesis of Beige Adipocytes Differentiated from Human Adipose-Derived Stem Cells by Balancing Mitochondrial Dynamics

1
1. scibot 25 Jun 2022
  
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  RRID:Addgene_10879
  
  DOI: 10.3390/ijms23126764
  
  Resource: RRID:Addgene_10879
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9224253/
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Single-cell RNA-seq of a soft-tissue sarcoma model reveals the critical role of tumor-expressed MIF in shaping macrophage heterogeneity

1
1. scibot 22 Jun 2022
  
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  Addgene_10879
  
  DOI: 10.1016/j.celrep.2022.110977
  
  Resource: RRID:Addgene_10879
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S221112472200763X
Jun 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SIRT1 regulates sphingolipid metabolism and neural differentiation of mouse embryonic stem cells through c-Myc-SMPDL3B

1
1. scibot 26 Jun 2021
  
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  RRID:Addgene_10879
  
  DOI: 10.7554/eLife.67452
  
  Resource: RRID:Addgene_10879
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8216717/
May 2021
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Repression of endogenous retroviruses prevents antiviral immune response and is required for mammary gland development

1
1. scibot 19 May 2021
  
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  RRID:Addgene_10879
  
  DOI: 10.1016/j.stem.2021.04.030
  
  Resource: RRID:Addgene_10879
  
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sciencedirect.com/science/article/pii/S193459092100206X
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The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer

1
1. scibot 18 May 2021
  
  in Public
  
  Addgene_10879
  
  DOI: 10.1016/j.cell.2021.04.022
  
  Resource: RRID:Addgene_10879
  
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sciencedirect.com/science/article/pii/S009286742100502X
Sep 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Enhancer RNAs predict enhancer–gene regulatory links and are critical for enhancer function in neuronal systems

1
1. scibot 23 Sep 2020
  
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  RRID:Addgene_10879
  
  DOI: 10.1093/nar/gkaa671
  
  Resource: RRID:Addgene_10879
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_10879
  
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  RRID:Addgene_10879 RRIDCUR:Validated
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pubmed.ncbi.nlm.nih.gov/32810208/
Jan 2020
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Mitigating Antagonism between Transcription and Proliferation Allows Near-Deterministic Cellular Reprogramming

1
1. scibot 13 Jan 2020
  
  in Public
  
  Addgene_10879
  
  DOI: 10.1016/j.stem.2019.08.005
  
  Resource: RRID:Addgene_10879
  
  Curator: @ethanbadger
  
  SciCrunch record: Addgene_10879
  
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  RRID:Addgene_10879 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1934590919303406