53 Matching Annotations
  1. Nov 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TWEAK modulates the characteristics of periodontal ligament stem cells via the Fn14/NF-κB pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC12594511/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The key role of acss1 in mammary gland development and lactation: a study based on gene co-expression network analysis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12523080/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SIRT5-mediated desuccinylation of MTHFD2 enhances chemoresistance in breast cancer cells by reducing therapy-induced senescence
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    pmc.ncbi.nlm.nih.gov/articles/PMC12537947/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting SQLE-mediated cholesterol metabolism to enhance CD8+ T cell activation and immunotherapy efficacy in hepatocellular carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12481379/
  6. Oct 2025
  7. www.biorxiv.org www.biorxiv.org
    AGO1 in neural progenitor cells orchestrates brain development and sociability via LIN28A-REELIN axis
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    biorxiv.org/content/10.1101/2025.10.01.679670v1
  8. Sep 2025
  9. www.sciencedirect.com www.sciencedirect.com
    Mutant RIT1 cooperates with YAP to drive an EMT-like lung cancer state
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    sciencedirect.com/science/article/pii/S2211124725009568
  10. www.sciencedirect.com www.sciencedirect.com
    Nucleolar stress facilitates islet β cell senescence via hijacking the DNA damage response pathways
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    sciencedirect.com/science/article/pii/S2589004225017699
  11. Aug 2025
  12. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225017006-main-html.html
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    52.53.155.43/4445811476685d53e8e368f4c93f2019d1647905/1-s2.0-S2589004225017006-main-html.html
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NAMPT and NNMT released via extracellular vesicles and as soluble mediators are distinguished traits of BRAF inhibitor resistance of melanoma cells impacting on the tumor microenvironment
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    pmc.ncbi.nlm.nih.gov/articles/PMC12278642/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of nonsense-mediated decay in TDP-43 deficient neurons reveals novel cryptic exons
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    pmc.ncbi.nlm.nih.gov/articles/PMC12262666/
  15. Jul 2025
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TP53 missense–specific transcriptional plasticity drives resistance against cell cycle inhibitors in pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12227071/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DSG2 promotes pancreatic cancer stem cell maintenance via support of tumour and macrophage cellular cross-talk
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    pmc.ncbi.nlm.nih.gov/articles/PMC12227620/
  18. www.science.org www.science.org
    TP53 missense–specific transcriptional plasticity drives resistance against cell cycle inhibitors in pancreatic cancer
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    science.org/doi/10.1126/sciadv.adu2339
  19. www.nature.com www.nature.com
    Molecular docking and biological evaluation of a novel IWS1 inhibitor for the treatment of human retroperitoneal liposarcoma
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    nature.com/articles/s41598-025-07215-y
  20. Jun 2025
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Genome-Wide Synthetic Lethal Screen Identifies Spermidine Synthase as a Target to Enhance Erdafitinib Efficacy in FGFR-Mutant Bladder Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12167931/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PRPS activity tunes redox homeostasis in Myc-driven lymphoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12166406/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNA shielding of P65 is required to potentiate oncogenic inflammation in TET2 mutated clonal hematopoiesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11611684/
  24. Apr 2025
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Elevated VRK1 levels after androgen deprivation therapy promote prostate cancer progression by upregulating YAP1 expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11926012/
  26. Mar 2025
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    REDD1-dependent GSK3β signaling in podocytes promotes canonical NF-κB activation in diabetic nephropathy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11904504/
  28. www.sciencedirect.com www.sciencedirect.com
    PTPσ-mediated PI3P regulation modulates neurodegeneration in C9ORF72-ALS/FTD
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    sciencedirect.com/science/article/pii/S0896627325001187
  29. Sep 2024
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cysteine-rich with EGF-like domains 2 (CRELD2) is an endoplasmic reticulum stress-inducible angiogenic growth factor promoting ischemic heart repair
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    ncbi.nlm.nih.gov/pmc/articles/PMC11358006/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLC13A3 is a major effector downstream of activated β-catenin in liver cancer pathogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11364541/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic Profiling of Cochlear Organoids Identifies α‐Ketoglutarate and NAD+ as Limiting Factors for Hair Cell Reprogramming
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    ncbi.nlm.nih.gov/pmc/articles/PMC11425867/
  33. www.sciencedirect.com www.sciencedirect.com
    Hydrogen sulfide-mediated persulfidation regulates homocysteine metabolism and enhances ferroptosis in non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S1097276524007317
  34. Aug 2024
  35. www.sciencedirect.com www.sciencedirect.com
    Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence
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    sciencedirect.com/science/article/pii/S1097276524006609
  36. www.nature.com www.nature.com
    Compression-dependent microtubule reinforcement enables cells to navigate confined environments
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    nature.com/articles/s41556-024-01476-x
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRPS2‐mediated modulation of the antitumor immune response in lung cancer through CCL2‐mediated tumor‐associated macrophages and myeloid‐derived suppressor cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11320087/
  38. Jun 2024
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FOXA3 regulates cholesterol metabolism to compensate for low uptake during the progression of lung adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11161053/
  40. May 2024
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumour‐derived exosome SNHG17 induced by oestrogen contributes to ovarian cancer progression via the CCL13–CCR2–M2 macrophage axis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11056704/
  42. Apr 2024
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic targeting of cancer associated fibroblasts overcomes T-cell exclusion and chemoresistance in soft-tissue sarcomas
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    ncbi.nlm.nih.gov/pmc/articles/PMC10954767/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intrinsic and extrinsic actions of human neural progenitors with SUFU inhibition promote tissue repair and functional recovery from severe spinal cord injury
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    ncbi.nlm.nih.gov/pmc/articles/PMC10959923/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NLRP3 Inflammasome Priming in the Retina of Diabetic Mice Requires REDD1-Dependent Activation of GSK3β
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    ncbi.nlm.nih.gov/pmc/articles/PMC10981446/
  46. Mar 2024
  47. www.sciencedirect.com www.sciencedirect.com
    A gut-derived hormone regulates cholesterol metabolism
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    sciencedirect.com/science/article/pii/S0092867424002265
  48. Feb 2024
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cystine deprivation triggers CD36-mediated ferroptosis and dysfunction of tumor infiltrating CD8+ T cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10869360/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mcam inhibits macrophage-mediated development of mammary gland through non-canonical Wnt signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC10761817/
  51. Jan 2024
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EGFR core fucosylation, induced by hepatitis C virus, promotes TRIM40-mediated-RIG-I ubiquitination and suppresses interferon-I antiviral defenses
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    ncbi.nlm.nih.gov/pmc/articles/PMC10803816/
  53. Oct 2023
  54. www.sciencedirect.com www.sciencedirect.com
    Fibroblast activation protein drives tumor metastasis via a protease-independent role in invadopodia stabilization
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    sciencedirect.com/science/article/pii/S2211124723013141
  55. Sep 2023
  56. www.nature.com www.nature.com
    HERC1 deficiency causes osteopenia through transcriptional program dysregulation during bone remodeling
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    nature.com/articles/s41419-023-05549-x
  57. Aug 2023
  58. www.biorxiv.org www.biorxiv.org
    The endosomal sorting complex Retromer has a central role in systemic cholesterol homeostasis by controlling endo-lysosomal cholesterol transport in hepatocytes
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    biorxiv.org/content/10.1101/2023.08.09.552611v2
  59. Jul 2023
  60. www.sciencedirect.com www.sciencedirect.com
    mRNA stability and m6A are major determinants of subcellular mRNA localization in neurons
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    sciencedirect.com/science/article/pii/S1097276523004689
  61. www.sciencedirect.com www.sciencedirect.com
    REDD1-dependent GSK3β dephosphorylation promotes NF-κB activation and macrophage infiltration in the retina of diabetic mice
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    sciencedirect.com/science/article/pii/S0021925823020197
  62. Feb 2023
  63. www.sciencedirect.com www.sciencedirect.com
    Injury primes mutation-bearing astrocytes for dedifferentiation in later life
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    sciencedirect.com/science/article/pii/S0960982223001525
  64. Jan 2023
  65. www.sciencedirect.com www.sciencedirect.com
    Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy
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    sciencedirect.com/science/article/pii/S1535610822005943
  66. Oct 2022
  67. www.sciencedirect.com www.sciencedirect.com
    Stress response protein REDD1 promotes diabetes-induced retinal inflammation by sustaining canonical NF-κB signaling
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    sciencedirect.com/science/article/pii/S002192582201081X
  68. link.springer.com link.springer.com
    HERC2 deficiency activates C-RAF/MKK3/p38 signalling pathway altering the cellular response to oxidative stress
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    link.springer.com/article/10.1007/s00018-022-04586-7
  69. Jun 2022
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SAMM50 Regulates Thermogenesis of Beige Adipocytes Differentiated from Human Adipose-Derived Stem Cells by Balancing Mitochondrial Dynamics
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    ncbi.nlm.nih.gov/pmc/articles/PMC9224253/
  71. www.sciencedirect.com www.sciencedirect.com
    Single-cell RNA-seq of a soft-tissue sarcoma model reveals the critical role of tumor-expressed MIF in shaping macrophage heterogeneity
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    sciencedirect.com/science/article/pii/S221112472200763X
  72. Jun 2021
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SIRT1 regulates sphingolipid metabolism and neural differentiation of mouse embryonic stem cells through c-Myc-SMPDL3B
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    ncbi.nlm.nih.gov/pmc/articles/PMC8216717/
  74. May 2021
  75. www.sciencedirect.com www.sciencedirect.com
    Repression of endogenous retroviruses prevents antiviral immune response and is required for mammary gland development
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    sciencedirect.com/science/article/pii/S193459092100206X
  76. www.sciencedirect.com www.sciencedirect.com
    The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
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    sciencedirect.com/science/article/pii/S009286742100502X
  77. Sep 2020
  78. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Enhancer RNAs predict enhancer–gene regulatory links and are critical for enhancer function in neuronal systems
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    pubmed.ncbi.nlm.nih.gov/32810208/
  79. Jan 2020
  80. www.sciencedirect.com www.sciencedirect.com
    Mitigating Antagonism between Transcription and Proliferation Allows Near-Deterministic Cellular Reprogramming
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    sciencedirect.com/science/article/pii/S1934590919303406