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    Perturb-seq uncovers pathological obstacles to direct cardiac reprogramming in vivo
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  3. Mar 2026
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    DCPS modulates TDP-43-linked neurodegeneration through P-body-mediated RNA decay
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  5. Nov 2025
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    TWEAK modulates the characteristics of periodontal ligament stem cells via the Fn14/NF-κB pathway
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    The key role of acss1 in mammary gland development and lactation: a study based on gene co-expression network analysis
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    SIRT5-mediated desuccinylation of MTHFD2 enhances chemoresistance in breast cancer cells by reducing therapy-induced senescence
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    Targeting SQLE-mediated cholesterol metabolism to enhance CD8+ T cell activation and immunotherapy efficacy in hepatocellular carcinoma
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  10. Oct 2025
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    AGO1 in neural progenitor cells orchestrates brain development and sociability via LIN28A-REELIN axis
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  12. Sep 2025
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    Mutant RIT1 cooperates with YAP to drive an EMT-like lung cancer state
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    Nucleolar stress facilitates islet β cell senescence via hijacking the DNA damage response pathways
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    NAMPT and NNMT released via extracellular vesicles and as soluble mediators are distinguished traits of BRAF inhibitor resistance of melanoma cells impacting on the tumor microenvironment
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    Inhibition of nonsense-mediated decay in TDP-43 deficient neurons reveals novel cryptic exons
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  19. Jul 2025
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    TP53 missense–specific transcriptional plasticity drives resistance against cell cycle inhibitors in pancreatic cancer
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    DSG2 promotes pancreatic cancer stem cell maintenance via support of tumour and macrophage cellular cross-talk
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    TP53 missense–specific transcriptional plasticity drives resistance against cell cycle inhibitors in pancreatic cancer
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    Molecular docking and biological evaluation of a novel IWS1 inhibitor for the treatment of human retroperitoneal liposarcoma
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  24. Jun 2025
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    A Genome-Wide Synthetic Lethal Screen Identifies Spermidine Synthase as a Target to Enhance Erdafitinib Efficacy in FGFR-Mutant Bladder Cancer
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    PRPS activity tunes redox homeostasis in Myc-driven lymphoma
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    RNA shielding of P65 is required to potentiate oncogenic inflammation in TET2 mutated clonal hematopoiesis
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  28. Apr 2025
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    Elevated VRK1 levels after androgen deprivation therapy promote prostate cancer progression by upregulating YAP1 expression
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  30. Mar 2025
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    REDD1-dependent GSK3β signaling in podocytes promotes canonical NF-κB activation in diabetic nephropathy
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    PTPσ-mediated PI3P regulation modulates neurodegeneration in C9ORF72-ALS/FTD
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  33. Sep 2024
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    Metabolic Profiling of Cochlear Organoids Identifies α‐Ketoglutarate and NAD+ as Limiting Factors for Hair Cell Reprogramming
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    Hydrogen sulfide-mediated persulfidation regulates homocysteine metabolism and enhances ferroptosis in non-small cell lung cancer
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  38. Aug 2024
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    Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence
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  44. May 2024
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    Tumour‐derived exosome SNHG17 induced by oestrogen contributes to ovarian cancer progression via the CCL13–CCR2–M2 macrophage axis
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  46. Apr 2024
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    Intrinsic and extrinsic actions of human neural progenitors with SUFU inhibition promote tissue repair and functional recovery from severe spinal cord injury
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  50. Mar 2024
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    A gut-derived hormone regulates cholesterol metabolism
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  52. Feb 2024
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    Cystine deprivation triggers CD36-mediated ferroptosis and dysfunction of tumor infiltrating CD8+ T cells
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  55. Jan 2024
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    EGFR core fucosylation, induced by hepatitis C virus, promotes TRIM40-mediated-RIG-I ubiquitination and suppresses interferon-I antiviral defenses
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  57. Oct 2023
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  59. Sep 2023
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    HERC1 deficiency causes osteopenia through transcriptional program dysregulation during bone remodeling
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  61. Aug 2023
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    The endosomal sorting complex Retromer has a central role in systemic cholesterol homeostasis by controlling endo-lysosomal cholesterol transport in hepatocytes
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  63. Jul 2023
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    mRNA stability and m6A are major determinants of subcellular mRNA localization in neurons
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    REDD1-dependent GSK3β dephosphorylation promotes NF-κB activation and macrophage infiltration in the retina of diabetic mice
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  66. Feb 2023
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    Injury primes mutation-bearing astrocytes for dedifferentiation in later life
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  68. Jan 2023
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    Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy
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  70. Oct 2022
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    Stress response protein REDD1 promotes diabetes-induced retinal inflammation by sustaining canonical NF-κB signaling
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    HERC2 deficiency activates C-RAF/MKK3/p38 signalling pathway altering the cellular response to oxidative stress
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    link.springer.com/article/10.1007/s00018-022-04586-7
  73. Jun 2022
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    SAMM50 Regulates Thermogenesis of Beige Adipocytes Differentiated from Human Adipose-Derived Stem Cells by Balancing Mitochondrial Dynamics
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    Single-cell RNA-seq of a soft-tissue sarcoma model reveals the critical role of tumor-expressed MIF in shaping macrophage heterogeneity
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  76. Jun 2021
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    SIRT1 regulates sphingolipid metabolism and neural differentiation of mouse embryonic stem cells through c-Myc-SMPDL3B
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  78. May 2021
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    Repression of endogenous retroviruses prevents antiviral immune response and is required for mammary gland development
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    The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
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  81. Sep 2020
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    Enhancer RNAs predict enhancer–gene regulatory links and are critical for enhancer function in neuronal systems
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  83. Jan 2020
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    Mitigating Antagonism between Transcription and Proliferation Allows Near-Deterministic Cellular Reprogramming
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