Hypothesis

21 Matching Annotations

Last 7 days
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CRISPR-Cas9 screening reveals G2E3 as a novel ubiquitin-linked factor controlling autophagosome-lysosome fusion and cancer cell progression

1
1. scibot 14 Oct 2025
  
  in Public
  
  RRID:Addgene_110060
  
  DOI: 10.1038/s41420-025-02717-0
  
  Resource: RRID:Addgene_110060
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_110060
  
  What is this?
  
  RRID:Addgene_110060
Visit annotations in context

Tags

RRID:Addgene_110060

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12511632/
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

NAT10 Increases Lysosomal Acidification to Promote Esophageal Cancer Metastasis via ac4C Acetylation of ATP6V0E1 mRNA

1
1. scibot 06 Sep 2025
  
  in Public
  
  110060
  
  DOI: 10.1002/advs.202502931
  
  Resource: RRID:Addgene_110060
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_110060
  
  What is this?
  
  RRID:Addgene_110060
Visit annotations in context

Tags

RRID:Addgene_110060

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12376557/
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

AIMP3 maintains cardiac homeostasis by regulating the editing activity of methionyl-tRNA synthetase

1
1. scibot 20 Jul 2025
  
  in Public
  
  110060
  
  DOI: 10.1038/s44161-025-00670-w
  
  Resource: RRID:Addgene_110060
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_110060
  
  What is this?
  
  RRID:Addgene_110060
Visit annotations in context

Tags

RRID:Addgene_110060

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12259467/
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau

1
1. scibot 16 May 2025
  
  in Public
  
  FUW mCherry-GFP-LC3
  
  DOI: 10.1038/s41467-025-58585-w
  
  Resource: RRID:Addgene_110060
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_110060
  
  What is this?
  
  RRID:Addgene_110060
Visit annotations in context

Tags

RRID:Addgene_110060

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11982250/
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

DNA damage response regulator ATR licenses PINK1-mediated mitophagy

1
1. scibot 23 Mar 2025
  
  in Public
  
  110060
  
  DOI: 10.1093/nar/gkaf178
  
  Resource: RRID:Addgene_110060
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_110060
  
  What is this?
  
  RRID:Addgene_110060
Visit annotations in context

Tags

RRID:Addgene_110060

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11920799/
www.sciencedirect.com www.sciencedirect.com

PTPσ-mediated PI3P regulation modulates neurodegeneration in C9ORF72-ALS/FTD

1
1. scibot 13 Mar 2025
  
  in Public
  
  RRID:Addgene_110060
  
  DOI: 10.1016/j.neuron.2025.02.005
  
  Resource: RRID:Addgene_110060
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_110060
  
  What is this?
  
  RRID:Addgene_110060
Visit annotations in context

Tags

RRID:Addgene_110060

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0896627325001187
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

USP1 promotes pancreatic cancer progression and autophagy by deubiquitinating ATG14

1
1. scibot 11 Mar 2025
  
  in Public
  
  mCherry-LC3
  
  DOI: 10.1016/j.jbc.2025.108190
  
  Resource: RRID:Addgene_110060
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_110060
  
  What is this?
  
  RRID:Addgene_110060
Visit annotations in context

Tags

RRID:Addgene_110060

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11871461/
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

NEAT1-mediated regulation of proteostasis and mRNA localization impacts autophagy dysregulation in Rett syndrome

1
1. scibot 11 Feb 2025
  
  in Public
  
  RRID:Addgene_110060
  
  DOI: 10.1093/nar/gkaf074
  
  Resource: RRID:Addgene_110060
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_110060
  
  What is this?
  
  RRID:Addgene_110060
Visit annotations in context

Tags

RRID:Addgene_110060

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11806351/
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Spermidine Recovers the Autophagy Defects Underlying the Pathophysiology of Cell Trafficking Disorders

1
1. scibot 27 Jan 2025
  
  in Public
  
  110060
  
  DOI: 10.1002/jimd.12841
  
  Resource: RRID:Addgene_110060
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_110060
  
  What is this?
  
  RRID:Addgene_110060
Visit annotations in context

Tags

RRID:Addgene_110060

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11751594/
Oct 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Longitudinal modeling of human neuronal aging reveals the contribution of the RCAN1–TFEB pathway to Huntington’s disease neurodegeneration

1
1. scibot 08 Oct 2024
  
  in Public
  
  RRID:Addgene_110060
  
  DOI: 10.1038/s43587-023-00538-3
  
  Resource: RRID:Addgene_110060
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_110060
  
  What is this?
  
  RRID:Addgene_110060
Visit annotations in context

Tags

RRID:Addgene_110060

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11456361/
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Polyvinylpyrrolidone capped silver nanoparticles enhance the autophagic clearance of Acinetobacter baumannii from human pulmonary cells

1
1. scibot 27 Sep 2024
  
  in Public
  
  110060
  
  DOI: 10.1186/s11671-024-04107-4
  
  Resource: RRID:Addgene_110060
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_110060
  
  What is this?
  
  RRID:Addgene_110060
Visit annotations in context

Tags

RRID:Addgene_110060

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11420407/
Jul 2024
link.springer.com link.springer.com

Truncated tau interferes with the autophagy and endolysosomal pathway and results in lipid accumulation

1
1. scibot 19 Jul 2024
  
  in Public
  
  RRID:Addgene_110060
  
  DOI: 10.1007/s00018-024-05337-6
  
  Resource: RRID:Addgene_110060
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_110060
  
  What is this?
  
  RRID:Addgene_110060
Visit annotations in context

Tags

RRID:Addgene_110060

Annotators

scibot

URL

link.springer.com/article/10.1007/s00018-024-05337-6
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

FABP5-binding lipids regulate autophagy in differentiated SH-SY5Y cells

1
1. scibot 01 Jul 2024
  
  in Public
  
  plasmid_110060
  
  DOI: 10.1371/journal.pone.0300168
  
  Resource: RRID:Addgene_110060
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_110060
  
  What is this?
  
  RRID:Addgene_110060
Visit annotations in context

Tags

RRID:Addgene_110060

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11189175/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Multiplexed screening reveals how cancer-specific alternative polyadenylation shapes tumor growth in vivo

1
1. scibot 04 Feb 2024
  
  in Public
  
  Plasmid_110060
  
  DOI: 10.1038/s41467-024-44931-x
  
  Resource: RRID:Addgene_110060
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_110060
  
  What is this?
  
  RRID:Addgene_110060
Visit annotations in context

Tags

RRID:Addgene_110060

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10834521/
Dec 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Metixene is an incomplete autophagy inducer in preclinical models of metastatic cancer and brain metastases

1
1. scibot 16 Dec 2023
  
  in Public
  
  RRID:Addgene_110060
  
  DOI: 10.1172/JCI161142
  
  Resource: RRID:Addgene_110060
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_110060
  
  What is this?
  
  RRID:Addgene_110060
Visit annotations in context

Tags

RRID:Addgene_110060

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10721147/
Sep 2023
www.sciencedirect.com www.sciencedirect.com

Usp25-Erlin1/2 activity limits cholesterol flux to restrict virus infection

1
1. scibot 08 Sep 2023
  
  in Public
  
  plasmid_110060
  
  DOI: 10.1016/j.devcel.2023.08.013
  
  Resource: RRID:Addgene_110060
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_110060
  
  What is this?
  
  RRID:Addgene_110060
Visit annotations in context

Tags

RRID:Addgene_110060

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1534580723004094
Oct 2022
www.nature.com www.nature.com

Age-related Huntington’s disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy

1
1. scibot 28 Oct 2022
  
  in Public
  
  RRID:Addgene_110060
  
  DOI: 10.1038/s41593-022-01185-4
  
  Resource: RRID:Addgene_110060
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_110060
  
  What is this?
  
  RRID:Addgene_110060
Visit annotations in context

Tags

RRID:Addgene_110060

Annotators

scibot

URL

nature.com/articles/s41593-022-01185-4
Jun 2022
aacrjournals.org aacrjournals.org

Porcupine inhibition disrupts mitochondrial function and homeostasis in WNT ligand-addicted pancreatic cancer

1
1. scibot 14 Jun 2022
  
  in Public
  
  RRID:Addgene_110060
  
  DOI: 10.1158/1535-7163.MCT-21-0623
  
  Resource: RRID:Addgene_110060
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_110060
  
  What is this?
  
  RRID:Addgene_110060
Visit annotations in context

Tags

RRID:Addgene_110060

Annotators

scibot

URL

aacrjournals.org/mct/article/21/6/936/699192/Porcupine-Inhibition-Disrupts-Mitochondrial
Apr 2022
link.springer.com link.springer.com

Cannabidiol induces autophagy and improves neuronal health associated with SIRT1 mediated longevity

1
1. scibot 23 Apr 2022
  
  in Public
  
  RRID:Addgene_110060
  
  DOI: 10.1007/s11357-022-00559-7
  
  Resource: RRID:Addgene_110060
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_110060
  
  What is this?
  
  RRID:Addgene_110060
Visit annotations in context

Tags

RRID:Addgene_110060

Annotators

scibot

URL

link.springer.com/article/10.1007/s11357-022-00559-7
Jun 2021
www.tandfonline.com www.tandfonline.com

Garcinia cambogia attenuates adipogenesis by affecting CEBPB and SQSTM1/p62-mediated selective autophagic degradation of KLF3 through RPS6KA1 and STAT3 suppression

1
1. scibot 17 Jun 2021
  
  in Public
  
  RRID:Addgene_110060
  
  DOI: 10.1080/15548627.2021.1936356
  
  Resource: RRID:Addgene_110060
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_110060
  
  What is this?
  
  RRID:Addgene_110060
Visit annotations in context

Tags

RRID:Addgene_110060

Annotators

scibot

URL

tandfonline.com/doi/full/10.1080/15548627.2021.1936356
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The Antihistamine Deptropine Induces Hepatoma Cell Death through Blocking Autophagosome-Lysosome Fusion

1
1. scibot 17 Sep 2020
  
  in Public
  
  RRID:Addgene_110060
  
  DOI: 10.3390/cancers12061610
  
  Resource: RRID:Addgene_110060
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_110060
  
  What is this?
  
  RRID:Addgene_110060 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:Addgene_110060

RRIDCUR:Validated

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7352610/