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Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Systematic comparison and base-editing-mediated directed protein evolution and functional screening yield superior auxin-inducible degron technology

1
1. scibot 11 Aug 2025
  
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  112095
  
  DOI: 10.1038/s41467-025-61848-1
  
  Resource: RRID:Addgene_112095
  
  Curator: @olekpark
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12274581/
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Y12C mutation disrupts IMPDH cytoophidia and alters cancer metabolism

1
1. scibot 20 Jul 2025
  
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  112095
  
  DOI: 10.1111/febs.70086
  
  Resource: RRID:Addgene_112095
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12265856/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Establishment and rescue of fibroblast cell lines carrying a nonsense mutation of RB1 by CRISPR-based base editing

1
1. scibot 20 Jul 2025
  
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  112095
  
  DOI: 10.1038/s41598-025-10600-2
  
  Resource: RRID:Addgene_112095
  
  Curator: @olekpark
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12254293/
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Light-induced expression of gRNA allows for optogenetic gene editing of T lymphocytes in vivo

1
1. scibot 07 Apr 2025
  
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  112095
  
  DOI: 10.1093/nar/gkaf213
  
  Resource: RRID:Addgene_112095
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11925727/
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Keratin intermediate filaments mechanically position melanin pigments for genome photoprotection

1
1. scibot 11 Mar 2025
  
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  112095
  
  DOI: 10.1101/2025.01.15.632531
  
  Resource: RRID:Addgene_112095
  
  Curator: @olekpark
  
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  DOI:10.1101/2025.01.15.632531 RRID:Addgene_112095
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pmc.ncbi.nlm.nih.gov/articles/PMC11761041/
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Evolved cytidine and adenine base editors with high precision and minimized off-target activity by a continuous directed evolution system in mammalian cells

1
1. scibot 25 Sep 2024
  
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  112095
  
  DOI: 10.1038/s41467-024-52483-3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11408606/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Deep learning models incorporating endogenous factors beyond DNA sequences improve the prediction accuracy of base editing outcomes

1
1. scibot 29 Feb 2024
  
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  plasmid_112095
  
  DOI: 10.1038/s41421-023-00624-1
  
  Resource: RRID:Addgene_112095
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10879117/
May 2023
www.sciencedirect.com www.sciencedirect.com

Generation of a human embryonic stem cell line WAe009-A-79 carrying a long QT syndrome mutation in KCNQ1

1
1. scibot 11 May 2023
  
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  Addgene_112095
  
  DOI: 10.1016/j.scr.2023.103119
  
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sciencedirect.com/science/article/pii/S1873506123001058
Oct 2022
www.sciencedirect.com www.sciencedirect.com

Mechanisms and significance of tissue-specific MICU regulation of the mitochondrial calcium uniporter complex

1
1. scibot 07 Oct 2022
  
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  Addgene Cat#112095
  
  DOI: 10.1016/j.molcel.2022.09.006
  
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  Curator: @a5munoz
  
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sciencedirect.com/science/article/pii/S1097276522008954
Sep 2022
link.springer.com link.springer.com

Generation of corrected hiPSC clones from a Cornelia de Lange Syndrome (CdLS) patient through CRISPR-Cas-based technology

1
1. scibot 07 Sep 2022
  
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  RRID:Addgene_112095
  
  DOI: 10.1186/s13287-022-03135-0
  
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link.springer.com/article/10.1186/s13287-022-03135-0
May 2022
rupress.org rupress.org

Trapping of CDC42 C-terminal variants in the Golgi drives pyrin inflammasome hyperactivation

1
1. scibot 27 May 2022
  
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  plasmid_112095
  
  DOI: 10.1084/jem.20211889
  
  Resource: RRID:Addgene_112095
  
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rupress.org/jem/article/219/6/e20211889/213184/Trapping-of-CDC42-C-terminal-variants-in-the-Golgi
www.researchsquare.com www.researchsquare.com

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1
1. scibot 20 May 2022
  
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  RRID:Addgene_112095
  
  DOI: 10.21203/rs.3.rs-658360/v1
  
  Resource: RRID:Addgene_112095
  
  Curator: @scibot
  
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researchsquare.com/article/rs-6955925/'https://www.researchsquare.com/article/rs-6955925/v1
Nov 2021
www.sciencedirect.com www.sciencedirect.com

Simultaneous high-efficiency base editing and reprogramming of patient fibroblasts

1
1. scibot 25 Nov 2021
  
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  RRID:Addgene_112095
  
  DOI: 10.1016/j.stemcr.2021.10.017
  
  Resource: RRID:Addgene_112095
  
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sciencedirect.com/science/article/pii/S221367112100552X
May 2021
www.sciencedirect.com www.sciencedirect.com

Adenine base editing and prime editing of chemically derived hepatic progenitors rescue genetic liver disease

1
1. scibot 05 May 2021
  
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  Addgene_112095
  
  DOI: 10.1016/j.stem.2021.04.010
  
  Resource: RRID:Addgene_112095
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_112095
  
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  RRID:Addgene_112095
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sciencedirect.com/science/article/pii/S1934590921001673