60 Matching Annotations
  1. Aug 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acetylated mitochondrial MDH2 regulates CTR2 transcription to induce cuproptosis during Escherichia coli infection
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    pmc.ncbi.nlm.nih.gov/articles/PMC13402674/
  3. Jul 2026
  4. www.sciencedirect.com www.sciencedirect.com
    FGF21 synergizes with leptin to counteract obesity-related metabolic comorbidities by reversing hepatic leptin resistance
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    sciencedirect.com/science/article/pii/S1550413126002470
  5. Jun 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Redirection of SARS-CoV-2 to phagocytes by intranasal sACE2-Fc as a universal decoy confers complete prophylactic protection
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    pmc.ncbi.nlm.nih.gov/articles/PMC13183376/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acsl4-mediated Lipid Homeostasis Orchestrates Synaptic and Cognitive Plasticity
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC13142639/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tissue-selective COPII modulator SEC16B aggravates cardiovascular disease by promoting lipid export
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    pmc.ncbi.nlm.nih.gov/articles/PMC13226660/
  9. May 2026
  10. www.biorxiv.org www.biorxiv.org
    YY1 Binding Motif at Upstream of Rep/Cap Increases AAV Yield and Full Capsids
    1
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    biorxiv.org/content/10.64898/2026.05.21.726733v1
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modelling kidney cystogenesis using human kidney tubuloid cultures
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    pmc.ncbi.nlm.nih.gov/articles/PMC13162504/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Drug-induced changes in connectivity to midbrain dopamine cells revealed by rabies monosynaptic tracing
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    pmc.ncbi.nlm.nih.gov/articles/PMC13179063/
  13. www.sciencedirect.com www.sciencedirect.com
    Recombinant dimeric PICK1 peptide inhibitors for long-term relief of chronic pain by AAV therapeutics
    1
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    sciencedirect.com/science/article/pii/S266637912600217X
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hepatocyte-targeted Bap1 reduction in the liver primes an inflammatory transcriptional response
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC13148380/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Defining a Midgestational Window for In Utero Genome Editing of the Fetal Murine Cortex
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC13142468/
  16. Apr 2026
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single-cell omics reveals arg-1 as a key regulator of age-dependent macrophage-mediated cartilage repair
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    pmc.ncbi.nlm.nih.gov/articles/PMC12974833/
  18. Feb 2026
  19. www.sciencedirect.com www.sciencedirect.com
    Liver exerkine reverses aging- and Alzheimer’s-related memory loss via vasculature
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    sciencedirect.com/science/article/pii/S009286742600111X
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Engineering of High‐Yield Recombinant Adeno‐Associated Virus Producer Plasmids
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12802539/
  21. Nov 2025
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chronologically distributed transfection improves AAV2 and AAV2/8 capsid filling and reveals assembly schedule divergence
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12554105/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting prostaglandin E2 receptor 2 in Schwann cells inhibits inflammatory pain but not inflammation
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12462433/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IL-22 Exacerbates Coxsackievirus Type B3-Induced Pancreatitis by Elevating Viral Replication Through STAT3 Activation
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12599472/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Revealing acute consequences of rapid degradation of synaptic fusion proteins at individual synapses using Auxin-Inducible Degron 2 technology
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12623870/
  26. Sep 2025
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Development of LC-MS methods for AAV capsid protein quantification and host cell protein profiling
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12410343/
  28. Aug 2025
  29. www.sciencedirect.com www.sciencedirect.com
    Hepatocyte metabolic adaptations during pregnancy and lactation
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    sciencedirect.com/science/article/pii/S0092867425009213
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of FMRP in microglia promotes degeneration of parvalbumin neurons and audiogenic seizures via progranulin insufficiency
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12265543/
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sustained high expression of human FVII following AAV8-mediated gene delivery in mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12282199/
  32. Jul 2025
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The microprotein C16orf74/MICT1 promotes thermogenesis in brown adipose tissue
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12170882/
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A synthetic platform for developing recombinant adeno‐associated virus type 8 producer cell lines
    2
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    pmc.ncbi.nlm.nih.gov/articles/PMC12171320/
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Deep-tissue high-sensitivity multimodal imaging and optogenetic manipulation enabled by biliverdin reductase knockout
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12260061/
  36. 52.53.155.43 52.53.155.43
    matienzo-et-al-2025-adipocyte-specific-modulation-of-11β-hsd-enzymes-for-the-treatment-of-obesity-in-male-mice-html.html
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    52.53.155.43/0eec343059498565fba813ed54e166140d5ee93f/matienzo-et-al-2025-adipocyte-specific-modulation-of-11β-hsd-enzymes-for-the-treatment-of-obesity-in-male-mice-html.html
  37. www.journal-of-hepatology.eu www.journal-of-hepatology.eu
    Somatic loss-of-function mutations in CIDEB reduce hepatic steatosis by increasing lipolysis and fatty acid oxidation
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    journal-of-hepatology.eu/article/S0168-8278(25)02320-7/fulltext
  38. Jun 2025
  39. www.sciencedirect.com www.sciencedirect.com
    Protocol for adeno-associated virus-mediated gene delivery to accelerate pancreatic carcinogenesis in mice
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    sciencedirect.com/science/article/pii/S2666166725003132
  40. May 2025
  41. www.sciencedirect.com www.sciencedirect.com
    Specific targeting of brain endothelial cells using enhancer AAV vectors
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    sciencedirect.com/science/article/pii/S089662732500251X
  42. www.sciencedirect.com www.sciencedirect.com
    Small molecule inhibition of SUMOylation increases expression from AAV vectors both during and after initial transduction in mice
    1
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    sciencedirect.com/science/article/pii/S1525001625002965
  43. Mar 2025
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Use of an oversized AAV8 vector for CPS1 deficiency results in long-term survival and ammonia control
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11905892/
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SLC13A2 promotes hepatocyte metabolic remodeling and liver regeneration by enhancing de novo cholesterol biosynthesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11876347/
  46. Jan 2025
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Rational engineering of minimally immunogenic nucleases for gene therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11696374/
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting pleuro-alveolar junctions reverses lung fibrosis in mice
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11696612/
  49. Dec 2024
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TXNIP regulates pulmonary inflammation induced by Asian sand dust
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    pmc.ncbi.nlm.nih.gov/articles/PMC11671764/
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Quantitative proteomic analysis of residual host cell protein retention across adeno-associated virus affinity chromatography
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    pmc.ncbi.nlm.nih.gov/articles/PMC11650319/
  52. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Free Cholesterol-Induced Liver Injury in Non-Alcoholic Fatty Liver Disease: Mechanisms and a Therapeutic Intervention Using Dihydrotanshinone I
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    onlinelibrary.wiley.com/doi/full/10.1002/advs.202406191
  53. Nov 2024
  54. www.sciencedirect.com www.sciencedirect.com
    Modulation of AAV transduction and integration targeting by topoisomerase poisons
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    sciencedirect.com/science/article/pii/S2329050124001803
  55. Sep 2024
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KHSRP ameliorates acute liver failure by regulating pre-mRNA splicing through its interaction with SF3B1
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11347664/
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biolayer interferometry for adeno-associated virus capsid titer measurement and applications to upstream and downstream process development
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11365433/
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of genes supporting cold resistance of mammalian cells: lessons from a hibernator
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    ncbi.nlm.nih.gov/pmc/articles/PMC11413375/
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Simple and highly specific targeting of resident microglia with adeno-associated virus
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11407971/
  60. Aug 2024
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Liver matrin-3 protects mice against hepatic steatosis and stress response via constitutive androstane receptor
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11267048/
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vivo interaction screening reveals liver-derived constraints to metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11306111/
  63. Jun 2024
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AAV Capsid Screening for Translational Pig Research Using a Mouse Xenograft Liver Model
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    ncbi.nlm.nih.gov/pmc/articles/PMC11160762/
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    P2Y13 receptor deficiency favors adipose tissue lipolysis and worsens insulin resistance and fatty liver disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC11141875/
  66. May 2024
  67. www.biorxiv.org www.biorxiv.org
    Optimal AAV capsid/promoter combinations to target specific cell types in the common marmoset cerebral cortex
    1
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    biorxiv.org/content/10.1101/2024.05.09.593444v1
  68. www.nature.com www.nature.com
    Hepatocytes coordinate immune evasion in cancer via release of serum amyloid A proteins
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    nature.com/articles/s41590-024-01820-1
  69. Apr 2024
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rapid in vivo evaluation system for cholestasis-related genes in mice with humanized bile acid profiles
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    ncbi.nlm.nih.gov/pmc/articles/PMC10962888/
  71. Mar 2024
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DGAT2 inhibition blocks SREBP-1 cleavage and improves hepatic steatosis by increasing phosphatidylethanolamine in the ER
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    ncbi.nlm.nih.gov/pmc/articles/PMC10939742/
  73. Feb 2024
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engineered poly(A)-surrogates for translational regulation and therapeutic biocomputation in mammalian cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10770082/
  75. Apr 2023
  76. www.sciencedirect.com www.sciencedirect.com
    Berberine activates PPARδ and promotes gut microbiota-derived butyric acid to suppress hepatocellular carcinoma
    2
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    sciencedirect.com/science/article/pii/S0944711323002039
  77. Nov 2022
  78. www.sciencedirect.com www.sciencedirect.com
    Neural circuit-specific gene manipulation in mouse brain in vivo using split-intein-mediated split-Cre system
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    sciencedirect.com/science/article/pii/S2666166722006876
  79. Jun 2022
  80. www.sciencedirect.com www.sciencedirect.com
    Neural circuit pathology driven by Shank3 mutation disrupts social behaviors
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    sciencedirect.com/science/article/pii/S2211124722006817
  81. Nov 2021
  82. www.sciencedirect.com www.sciencedirect.com
    Impaired glucocorticoid receptor expression in liver disrupts feeding-induced gene expression, glucose uptake, and glycogen storage
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    sciencedirect.com/science/article/pii/S221112472101411X
  83. Sep 2021
  84. www.sciencedirect.com www.sciencedirect.com
    Revisiting astrocyte to neuron conversion with lineage tracing in vivo
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    sciencedirect.com/science/article/pii/S0092867421010527
  85. www.sciencedirect.com www.sciencedirect.com
    Homeostatic control of nuclear-encoded mitochondrial gene expression by the histone variant H2A.Z is essential for neuronal survival
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    sciencedirect.com/science/article/pii/S2211124721011517
  86. Jan 2021
  87. www.frontiersin.org www.frontiersin.org
    Overloaded Adeno-Associated Virus as a Novel Gene Therapeutic Tool for Otoferlin-Related Deafness
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    frontiersin.org/article/10.3389/fnmol.2020.600051/full