Hypothesis

43 Matching Annotations

Mar 2026
54.241.53.176 54.241.53.176

1-s2.0-S3117387X26000546-main-html.html

1
1. scibot 13 Mar 2026
  
  in Public
  
  RRID:Addgene_12252
  
  DOI: 10.1016/j.omta.2026.201719
  
  Resource: RRID:Addgene_12252
  
  Curator: @scibot
  
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54.241.53.176/fdb5d543653fe35ff3028eeff6ea9617ef4dafd3/1-s2.0-S3117387X26000546-main-html.html
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Developing and optimizing a biocompatible tauopathy model using extracellular vesicle-mediated gene delivery

1
1. scibot 24 Nov 2025
  
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  12252
  
  DOI: 10.3389/fmed.2025.1672046
  
  Resource: RRID:Addgene_12252
  
  Curator: @olekpark
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12587183/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Structure and function of Full-length Tau

1
1. scibot 24 Nov 2025
  
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  12252
  
  DOI: 10.1371/journal.pone.0335251
  
  Resource: RRID:Addgene_12252
  
  Curator: @olekpark
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12578172/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

SLC20A1 knockout to stably express a fusogenic gibbon ape leukemia virus envelope glycoprotein for lentiviral vector production

1
1. scibot 24 Nov 2025
  
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  12252
  
  DOI: 10.1016/j.omtm.2025.101619
  
  Resource: RRID:Addgene_12252
  
  Curator: @olekpark
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12639841/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Generation of Human 3D Airway Assembloids for Advanced Modeling

1
1. scibot 24 Nov 2025
  
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  plasmid_12252
  
  DOI: 10.7150/ijbs.113920
  
  Resource: RRID:Addgene_12252
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12594573/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Delivering Progranulin to Astrocytic Lysosomes Promotes Growth of Co‐Cultured Neurons

1
1. scibot 07 Nov 2025
  
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  RRID:Addgene_12252
  
  DOI: 10.1111/jnc.70284
  
  Resource: RRID:Addgene_12252
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12580966/
Oct 2025
www.pnas.org www.pnas.org

Inflammation awakens dormant cancer cells by modulating the epithelial–mesenchymal phenotypic state

1
1. scibot 29 Oct 2025
  
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  RRID:Addgene_12252
  
  DOI: 10.1073/pnas.2515009122
  
  Resource: RRID:Addgene_12252
  
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pnas.org/doi/abs/10.1073/pnas.2515009122
Aug 2025
www.cell.com www.cell.com

All-in-one vectors for epigenetic CRISPR inhibition of DUX4-fl in facioscapulohumeral muscular dystrophy

1
1. scibot 15 Aug 2025
  
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  RRID:Addgene_12252
  
  DOI: 10.1016/j.omtm.2025.101546
  
  Resource: RRID:Addgene_12252
  
  Curator: @scibot
  
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cell.com/molecular-therapy-family/methods/abstract/S2329-0501(25)00141-X
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Knockdown of the type 1 cannabinoid receptor in the central amygdala increases both spontaneous and water deprivation-induced sodium intake in rats

1
1. scibot 20 Jul 2025
  
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  pRRL.SIN.CPPT.CMV.GFP.WPRE
  
  DOI: 10.1152/ajpregu.00241.2024
  
  Resource: RRID:Addgene_12252
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_12252
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7617795/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Activated T Cells Break Tumor Immunosuppression by Macrophage Reeducation

1
1. scibot 08 Jul 2025
  
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  plasmid_12252
  
  DOI: 10.1158/2159-8290.CD-24-0415
  
  Resource: RRID:Addgene_12252
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_12252
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12223510/
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Anti-CD45 PBD-based antibody-drug conjugates are effective targeted conditioning agents for gene therapy and stem cell transplant

1
1. scibot 11 Jun 2025
  
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  RRID:Addgene_12252
  
  DOI: 10.1016/j.ymthe.2024.03.032
  
  Resource: RRID:Addgene_12252
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_12252
  
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  RRID:Addgene_12252
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pmc.ncbi.nlm.nih.gov/articles/PMC11184310/
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Large-scale discovery of potent, compact and erythroid specific enhancers for gene therapy vectors

1
1. scibot 19 May 2025
  
  in Public
  
  plasmid_12252
  
  DOI: 10.1038/s41467-025-59235-x
  
  Resource: RRID:Addgene_12252
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_12252
  
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  RRID:Addgene_12252
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pmc.ncbi.nlm.nih.gov/articles/PMC12064758/
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Overexpression of NKG2D and IL24 in NK Cell-Derived Exosomes for Cancer Therapy

1
1. scibot 23 Mar 2025
  
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  12252
  
  DOI: 10.3390/ijms26052098
  
  Resource: RRID:Addgene_12252
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_12252
  
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  RRID:Addgene_12252
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pmc.ncbi.nlm.nih.gov/articles/PMC11901126/
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Nuclear N-WASP Induces Actin Polymerization in the Nucleus with Cortactin as an Essential Factor

1
1. scibot 27 Jan 2025
  
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  plasmid_12252
  
  DOI: 10.3390/cells14010059
  
  Resource: RRID:Addgene_12252
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_12252
  
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  RRID:Addgene_12252
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pmc.ncbi.nlm.nih.gov/articles/PMC11720165/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Co-isolation of human donor eye cells and development of oncogene-mutated melanocytes to study uveal melanoma

1
1. scibot 27 Jan 2025
  
  in Public
  
  plasmid_12
  
  DOI: 10.1186/s12915-025-02118-w
  
  Resource: None
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_12252
  
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  RRIDCUR:Unresolved RRIDCUR:Incorrect RRID:Addgene_12252
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RRIDCUR:Unresolved

RRID:Addgene_12252

RRIDCUR:Incorrect

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11752652/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

EphA3-targeted chimeric antigen receptor T cells are effective in glioma and generate curative memory T cell responses

1
1. scibot 22 Aug 2024
  
  in Public
  
  Addgene_12252
  
  DOI: 10.1136/jitc-2024-009486
  
  Resource: RRID:Addgene_12252
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_12252
  
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  RRID:Addgene_12252
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ncbi.nlm.nih.gov/pmc/articles/PMC11308882/
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Influence of RNA circularity on Target RNA-Directed MicroRNA Degradation

1
1. scibot 23 Apr 2024
  
  in Public
  
  12252
  
  DOI: 10.1093/nar/gkae094
  
  Resource: RRID:Addgene_12252
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_12252
  
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  RRID:Addgene_12252
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ncbi.nlm.nih.gov/pmc/articles/PMC11014252/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

HIV-1 Reverse Transcriptase Expression in HPV16-Infected Epidermoid Carcinoma Cells Alters E6 Expression and Cellular Metabolism, and Induces a Hybrid Epithelial/Mesenchymal Cell Phenotype

1
1. scibot 28 Feb 2024
  
  in Public
  
  pRRLSIN.cPPT.PGK
  
  DOI: 10.3390/v16020193
  
  Resource: RRID:Addgene_12252
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_12252
  
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  RRID:Addgene_12252
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ncbi.nlm.nih.gov/pmc/articles/PMC10892743/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Combined therapy of CAR-IL-15/IL-15Rα-T cells and GLIPR1 knockdown in cancer cells enhanced anti-tumor effect against gastric cancer

1
1. scibot 21 Feb 2024
  
  in Public
  
  pRRLSIN.cPPT-GFP.WPRE
  
  DOI: 10.1186/s12967-024-04982-6
  
  Resource: RRID:Addgene_12252
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_12252
  
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  RRID:Addgene_12252
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scibot

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ncbi.nlm.nih.gov/pmc/articles/PMC10874561/
cancerci.biomedcentral.com cancerci.biomedcentral.com

NY-ESO-1-specific T cell receptor-engineered T cells and Tranilast, a TRPV2 antagonist bivalent treatment enhances the killing of esophageal cancer: a dual-targeted cancer therapeutic route

1
1. scibot 14 Feb 2024
  
  in Public
  
  Addgene #12252
  
  DOI: 10.1186/s12935-024-03249-w
  
  Resource: RRID:Addgene_12252
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_12252
  
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  RRID:Addgene_12252
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scibot

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cancerci.biomedcentral.com/articles/10.1186/s12935-024-03249-w
Oct 2023
www.biorxiv.org www.biorxiv.org

Large-scale discovery of potent, compact and lineage specific enhancers for gene therapy vectors

1
1. scibot 13 Oct 2023
  
  in Public
  
  plasmid_12252
  
  DOI: 10.1101/2023.10.04.559165
  
  Resource: RRID:Addgene_12252
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_12252
  
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  RRID:Addgene_12252
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biorxiv.org/content/10.1101/2023.10.04.559165v1
Sep 2023
www.sciencedirect.com www.sciencedirect.com

Antibodies targeting a quaternary site on SARS-CoV-2 spike glycoprotein prevent viral receptor engagement by conformational locking

1
1. scibot 30 Sep 2023
  
  in Public
  
  RRID:Addgene_12252
  
  DOI: 10.1016/j.immuni.2023.09.003
  
  Resource: RRID:Addgene_12252
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_12252
  
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  RRID:Addgene_12252
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scibot

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sciencedirect.com/science/article/pii/S1074761323004089
onlinelibrary.wiley.com onlinelibrary.wiley.com

Insights into product and process related challenges of lentiviral vector bioprocessing

1
1. scibot 29 Sep 2023
  
  in Public
  
  RRID:Addgene_12252
  
  DOI: 10.1002/bit.28498
  
  Resource: RRID:Addgene_12252
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_12252
  
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  RRID:Addgene_12252
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onlinelibrary.wiley.com/doi/10.1002/bit.28498
May 2023
elifesciences.org elifesciences.org

Human DUX4 and mouse Dux interact with STAT1 and broadly inhibit interferon-stimulated gene induction

1
1. scibot 21 May 2023
  
  in Public
  
  plasmid_12252
  
  DOI: 10.7554/eLife.82057
  
  Resource: RRID:Addgene_12252
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_12252
  
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  RRID:Addgene_12252
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elifesciences.org/articles/82057
Apr 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PTPN22 R620W gene editing in T cells enhances low-avidity TCR responses

1
1. scibot 04 Apr 2023
  
  in Public
  
  plasmid_12252
  
  DOI: 10.7554/eLife.81577
  
  Resource: RRID:Addgene_12252
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_12252
  
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  RRID:Addgene_12252
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ncbi.nlm.nih.gov/pmc/articles/PMC10065793/
Jan 2023
aacrjournals.org aacrjournals.org

Enhancing PD-L1 Degradation by ITCH during MAPK Inhibitor Therapy Suppresses Acquired Resistance

1
1. scibot 11 Jan 2023
  
  in Public
  
  RRID:Addgene_12252
  
  DOI: 10.1158/2159-8290.CD-21-1463
  
  Resource: RRID:Addgene_12252
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_12252
  
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  RRID:Addgene_12252
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scibot

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aacrjournals.org/cancerdiscovery/article/12/8/1942/707227/Enhancing-PD-L1-Degradation-by-ITCH-during-MAPK
Nov 2022
elifesciences.org elifesciences.org

Contrasting effects of Ksr2, an obesity gene, on trabecular bone volume and bone marrow adiposity

1
1. scibot 10 Nov 2022
  
  in Public
  
  RRID:Addgene_12252
  
  DOI: 10.7554/eLife.82810
  
  Resource: RRID:Addgene_12252
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_12252
  
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  RRID:Addgene_12252
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scibot

URL

elifesciences.org/articles/82810
Sep 2022
www.sciencedirect.com www.sciencedirect.com

SMN controls neuromuscular junction integrity through U7 snRNP

1
1. scibot 21 Sep 2022
  
  in Public
  
  RRID:Addgene_12252
  
  DOI: 10.1016/j.celrep.2022.111393
  
  Resource: RRID:Addgene_12252
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_12252
  
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  RRID:Addgene_12252
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scibot

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sciencedirect.com/science/article/pii/S221112472201230X
Jun 2022
www.sciencedirect.com www.sciencedirect.com

The focal adhesion protein β-parvin controls cardiomyocyte shape and sarcomere assembly in response to mechanical load

2
1. scibot 10 Jun 2022
  
  in Public
  
  Addgene, RRID: 12252
  
  DOI: 10.1016/j.cub.2022.05.047
  
  Resource: RRID:Addgene_12252
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:Addgene_12252
  
  What is this?
  
  RRID:Addgene_12252
2. scibot 10 Jun 2022
  
  in Public
  
  RRID:Addgene_12252
  
  DOI: 10.1016/j.cub.2022.05.047
  
  Resource: RRID:Addgene_12252
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_12252
  
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  RRID:Addgene_12252
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scibot

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sciencedirect.com/science/article/pii/S0960982222008508
Mar 2022
www.sciencedirect.com www.sciencedirect.com

12 months is a pivotal age for olfactory perceptual learning and its underlying neuronal plasticity in aging mice

1
1. scibot 18 Mar 2022
  
  in Public
  
  Addgene_12252
  
  DOI: 10.1016/j.neurobiolaging.2022.03.003
  
  Resource: RRID:Addgene_12252
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_12252
  
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  RRID:Addgene_12252
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URL

sciencedirect.com/science/article/pii/S0197458022000458
Oct 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A guide in lentiviral vector production for hard-to-transfect cells, using cardiac-derived c-kit expressing cells as a model system

1
1. scibot 02 Oct 2021
  
  in Public
  
  RRID:Addgene_12252
  
  DOI: 10.1038/s41598-021-98657-7
  
  Resource: RRID:Addgene_12252
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_12252
  
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  RRID:Addgene_12252
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URL

ncbi.nlm.nih.gov/pmc/articles/PMC8478948/
Sep 2021
www.sciencedirect.com www.sciencedirect.com

Discovery of synthetic lethal and tumor suppressor paralog pairs in the human genome

1
1. scibot 02 Sep 2021
  
  in Public
  
  Addgene: 12252
  
  DOI: 10.1016/j.celrep.2021.109597
  
  Resource: RRID:Addgene_12252
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_12252
  
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  RRID:Addgene_12252
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scibot

URL

sciencedirect.com/science/article/pii/S2211124721010354
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Stasimon Contributes to the Loss of Sensory Synapses and Motor Neuron Death in a Mouse Model of Spinal Muscular Atrophy

1
1. scibot 30 Jul 2021
  
  in Public
  
  AddgenePlasmid 12252
  
  DOI: 10.1016/j.celrep.2019.11.058
  
  Resource: RRID:Addgene_12252
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_12252
  
  What is this?
  
  RRID:Addgene_12252 RRIDCUR:Unrecognized
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RRIDCUR:Unrecognized

RRID:Addgene_12252

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719315499
academic.oup.com academic.oup.com

Negative Regulator of Ubiquitin-Like Protein 1 modulates the autophagy-lysosomal pathway via p62 to facilitate the extracellular release of tau following proteasome impairment

1
1. scibot 27 Jul 2021
  
  in Public
  
  RRID:Addgene_12
  
  DOI: 10.1093/hmg/ddz255
  
  Resource: RRID:Addgene_12252
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_12252
  
  Curator comments: pRRLSIN.cPPT.PGK-GFP.WPRE
  
  What is this?
  
  RRID:Addgene_12252 RRIDCUR:Unresolved RRIDCUR:SyntaxError
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RRIDCUR:SyntaxError

RRIDCUR:Unresolved

RRID:Addgene_12252

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scibot

URL

academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddz255/5613690
link.springer.com link.springer.com

Induced pluripotent stem cell macrophages present antigen to proinsulin-specific T cell receptors from donor-matched islet-infiltrating T cells in type 1 diabetes

1
1. scibot 27 Jul 2021
  
  in Public
  
  RRID:Addgene_12
  
  DOI: 10.1007/s00125-019-04988-6
  
  Resource: RRID:Addgene_12252
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_12252
  
  Curator comments: PRRLSIN.CPPT.PGK-GFP.WPRE
  
  What is this?
  
  RRID:Addgene_12252 RRIDCUR:Unresolved RRIDCUR:SyntaxError
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RRIDCUR:SyntaxError

RRIDCUR:Unresolved

RRID:Addgene_12252

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scibot

URL

link.springer.com/article/10.1007/s00125-019-04988-6
www.sciencedirect.com www.sciencedirect.com

Delivering progranulin to neuronal lysosomes protects against excitotoxicity

1
1. scibot 24 Jul 2021
  
  in Public
  
  RRID:Addgene_12252
  
  DOI: 10.1016/j.jbc.2021.100993
  
  Resource: RRID:Addgene_12252
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_12252
  
  What is this?
  
  RRID:Addgene_12252
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RRID:Addgene_12252

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scibot

URL

sciencedirect.com/science/article/pii/S002192582100795X
May 2021
www.sciencedirect.com www.sciencedirect.com

Ligand Binding to the Collagen VI Receptor Triggers a Talin-to-RhoA Switch that Regulates Receptor Endocytosis

1
1. scibot 04 May 2021
  
  in Public
  
  12252
  
  DOI: 10.1016/j.devcel.2020.04.015
  
  Resource: RRID:Addgene_12252
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_12252
  
  What is this?
  
  RRID:Addgene_12252 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:Addgene_12252

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scibot

URL

sciencedirect.com/science/article/pii/S1534580720303178
Feb 2021
elifesciences.org elifesciences.org

Sequentially induced motor neurons from human fibroblasts facilitate locomotor recovery in a rodent spinal cord injury model

1
1. scibot 25 Feb 2021
  
  in Public
  
  RRID:Addgene_12252
  
  DOI: 10.7554/eLife.52069
  
  Resource: RRID:Addgene_12252
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_12252
  
  What is this?
  
  RRID:Addgene_12252
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RRID:Addgene_12252

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scibot

URL

elifesciences.org/articles/52069
Jan 2021
www.cell.com www.cell.com

Targeted epigenetic repression by CRISPR/dSaCas9 suppresses pathogenic DUX4-fl expression in FSHD

1
1. scibot 30 Jan 2021
  
  in Public
  
  RRID:Addgene_12252
  
  DOI: 10.1016/j.omtm.2020.12.001
  
  Resource: RRID:Addgene_12252
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_12252
  
  What is this?
  
  RRID:Addgene_12252 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:Addgene_12252

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scibot

URL

cell.com/molecular-therapy-family/methods/abstract/S2329-0501(20)30249-7
Sep 2020
elifesciences.org elifesciences.org

A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation

1
1. scibot 17 Sep 2020
  
  in Public
  
  RRID:Addgene_12252
  
  DOI: 10.7554/eLife.58659
  
  Resource: RRID:Addgene_12252
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_12252
  
  What is this?
  
  RRID:Addgene_12252 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:Addgene_12252

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scibot

URL

elifesciences.org/articles/58659
www.embopress.org www.embopress.org

Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development

1
1. scibot 05 Sep 2020
  
  in Public
  
  RRID:Addgene_12252
  
  DOI: 10.15252/embr.201949006
  
  Resource: RRID:Addgene_12252
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_12252
  
  What is this?
  
  RRIDCUR:Validated RRID:Addgene_12252
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RRIDCUR:Validated

RRID:Addgene_12252

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scibot

URL

embopress.org/doi/abs/10.15252/embr.201949006
link.springer.com link.springer.com

Intramembrane proteolysis of an extracellular serine protease, epithin/PRSS14, enables its intracellular nuclear function

1
1. scibot 04 Sep 2020
  
  in Public
  
  pRRLSIN.cPPT.PGK-GFP.WPRE
  
  DOI: 10.1186/s12915-020-00787-3
  
  Resource: RRID:Addgene_12252
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_12252
  
  Curator comments: pRRLSIN.cPPT.PGK-GFP.WPRE
  
  What is this?
  
  RRIDCUR:Missing RRID:Addgene_12252
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RRIDCUR:Missing

RRID:Addgene_12252

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scibot

URL

link.springer.com/article/10.1186/s12915-020-00787-3