91 Matching Annotations
  1. Oct 2025
  2. www.sciencedirect.com www.sciencedirect.com
    Arsenic regulates ALKBH1 abundance and substrate specificity to promote translation and tumorigenicity
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    sciencedirect.com/science/article/pii/S2211124725010824
  3. Aug 2025
  4. link.springer.com link.springer.com
    Transcription factor TFAP2A drives the growth and metastasis and blocks ferroptosis of triple-negative breast cancer by activating PRAME transcription
    1
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    link.springer.com/article/10.1007/s00210-025-04359-6
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The role of Nef in the long-term persistence of the replication-competent HIV reservoir in South African women
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    pmc.ncbi.nlm.nih.gov/articles/PMC12282088/
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IL-6 predicts CDK4/6 inhibitor resistance, identifying STAT3 as a target in HR + /HER2-negative metastatic breast cancer
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12297654/
  7. Jun 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Elucidating the genetic mechanisms governing cytosine base editing outcomes through CRISPRi screens
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    pmc.ncbi.nlm.nih.gov/articles/PMC12092667/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ONECUT2 reprograms neuroendocrine fate and is an actionable therapeutic target in small cell lung cancer
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12153148/
  10. May 2025
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Yoda1, a Piezo1 agonist, induced latent HIV reactivation associated with upregulation of CD3/TCR complex and HLA genes
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12036472/
  12. Apr 2025
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Using Nano-Luciferase Binary (NanoBiT) Technology to Assess the Interaction Between Viral Spike Protein and Angiotensin-Converting Enzyme II by Aptamers
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    pmc.ncbi.nlm.nih.gov/articles/PMC11940275/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LNS8801: An Enantiomerically Pure Agonist of the G Protein–Coupled Estrogen Receptor Suitable for Clinical Development
    2
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    pmc.ncbi.nlm.nih.gov/articles/PMC11969138/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The conserved HIV-1 spacer peptide 2 triggers matrix lattice maturation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11964938/
  16. Mar 2025
  17. www.sciencedirect.com www.sciencedirect.com
    ACVR2A attenuation impacts lactate production and hyperglycolytic conditions attracting regulatory T cells in hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S2666379125001119
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Development and Characterization of Three Novel FGFR Inhibitor Resistant Cervical Cancer Cell Lines to Help Drive Cervical Cancer Research
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    pmc.ncbi.nlm.nih.gov/articles/PMC11898767/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nuclear stiffness through lamin A/C overexpression differentially modulates chromosomal instability biomarkers
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    pmc.ncbi.nlm.nih.gov/articles/PMC11865694/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Adhesion strength of tumor cells predicts metastatic disease in vivo
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    pmc.ncbi.nlm.nih.gov/articles/PMC12014391/
  21. Feb 2025
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lysosomal NKG7 restrains mTORC1 activity to promote CD8+ T cell durability and tumor control
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    pmc.ncbi.nlm.nih.gov/articles/PMC11829009/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PlexinD1 is a driver and a therapeutic target in advanced prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11822115/
  24. Dec 2024
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PP2A B55α Inhibits Epithelial-Mesenchymal Transition Via Regulation of Slug Expression in Non-Small Cell Lung Cancer
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11670312/
  26. www.sciencedirect.com www.sciencedirect.com
    Commensal papillomavirus immunity preserves the homeostasis of highly mutated normal skin
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    sciencedirect.com/science/article/pii/S1535610824004483
  27. Sep 2024
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identifying a gene signature of metastatic potential by linking pre-metastatic state to ultimate metastatic fate
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11343111/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical spheroid models identify BMX as a therapeutic target for metastatic MYCN nonamplified neuroblastoma
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11383371/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Investigation of a fluorescent reporter microenvironment niche labeling strategy in experimental brain metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11261144/
  31. Aug 2024
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The exocyst subunit EXOC2 regulates the toxicity of expanded GGGGCC repeats in C9ORF72-ALS/FTD
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11299523/
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    Viral hijacking of hnRNPH1 unveils a G-quadruplex-driven mechanism of stress control
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    sciencedirect.com/science/article/pii/S1931312824002658
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human RNA Polymerase II Segregates from Genes and Nascent RNA and Transcribes in the Presence of DNA-Bound dCas9
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11312690/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HIV-1-envelope trimer transitions from prefusion-closed to CD4-bound-open conformations through an occluded-intermediate state
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11275901/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context-dependent roles for ubiquitous mitochondrial creatine kinase CKMT1 in breast cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11100297/
  37. Jul 2024
  38. www.sciencedirect.com www.sciencedirect.com
    Interface-guided phenotyping of coding variants in the transcription factor RUNX1
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    sciencedirect.com/science/article/pii/S2211124724007654
  39. www.cell.com www.cell.com
    Spontaneous and evoked synaptic vesicle release arises from a single releasable pool
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    cell.com/cell-reports/fulltext/S2211-1247(24)00790-3
  40. Jun 2024
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antiviral activity of intracellular nanobodies targeting the influenza virus RNA-polymerase core
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    ncbi.nlm.nih.gov/pmc/articles/PMC11210859/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SGIP1 binding to the α-helical H9 domain of cannabinoid receptor 1 promotes axonal surface expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11213518/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 NSP5 antagonizes MHC II expression by subverting histone deacetylase 2
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    ncbi.nlm.nih.gov/pmc/articles/PMC11166459/
  44. May 2024
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mecp2 fine-tunes quiescence exit by targeting nuclear receptors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11095939/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    E4BP4 in macrophages induces an anti-inflammatory phenotype that ameliorates the severity of colitis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11076557/
  47. Apr 2024
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation by the RNA-binding protein Unkempt at its effector interface
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    ncbi.nlm.nih.gov/pmc/articles/PMC11009413/
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    miR-147b mediated suppression of DUSP8 promotes lung cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11014796/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context-dependent roles for ubiquitous mitochondrial creatine kinase CKMT1 in breast cancer progression
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11100297/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A temperature-inducible protein module for control of mammalian cell fate
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    ncbi.nlm.nih.gov/pmc/articles/PMC10925237/
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiplexed dynamic control of temperature to probe and observe mammalian cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10983861/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Restored glyoxylate metabolism after AGXT gene correction and direct reprogramming of primary hyperoxaluria type 1 fibroblasts
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    ncbi.nlm.nih.gov/pmc/articles/PMC10993186/
  54. Mar 2024
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Actin-Dependent Mechanism of Tumor Progression Induced by a Dysfunction of p53 Tumor Suppressor
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    ncbi.nlm.nih.gov/pmc/articles/PMC10969470/
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct ontogenetic lineages dictate cDC2 heterogeneity
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    ncbi.nlm.nih.gov/pmc/articles/PMC10907303/
  57. Feb 2024
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The membrane-associated ubiquitin ligase MARCHF8 stabilizes the human papillomavirus oncoprotein E7 by degrading CUL1 and UBE2L3 in head and neck cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10878100/
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stromal-derived MAOB promotes prostate cancer growth and progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10857382/
  60. Jan 2024
  61. www.sciencedirect.com www.sciencedirect.com
    Cholinergic signaling via muscarinic M1 receptor confers resistance to docetaxel in prostate cancer
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    sciencedirect.com/science/article/pii/S2666379123006171
  62. Dec 2023
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A synthetic notch (synNotch) system linking intratumoral immune-cancer cell communication to a synthetic blood biomarker assay
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    ncbi.nlm.nih.gov/pmc/articles/PMC10740178/
  64. www.sciencedirect.com www.sciencedirect.com
    KDM5B predicts temozolomide-resistant subclones in glioblastoma
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    sciencedirect.com/science/article/pii/S2589004223026731
  65. Oct 2023
  66. www.biorxiv.org www.biorxiv.org
    A synthetic Notch (synNotch) system linking intratumoral immune-cancer cell communication to a synthetic blood biomarker assay
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    biorxiv.org/content/10.1101/2023.09.26.559329v1
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined Targeting of NAD Biosynthesis and the NAD-dependent Transcription Factor C-terminal Binding Protein as a Promising Novel Therapy for Pancreatic Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10549224/
  68. www.cell.com www.cell.com
    Methylation of KRAS by SETD7 promotes KRAS degradation in non-small cell lung cancer
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    cell.com/cell-reports/abstract/S2211-1247(23)01014-8
  69. Sep 2023
  70. www.sciencedirect.com www.sciencedirect.com
    Hyperpolarization-activated cyclic nucleotide-gated cation channel 3 promotes HCC development in a female-biased manner
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    sciencedirect.com/science/article/pii/S2211124723011695
  71. link.springer.com link.springer.com
    Host-derived growth factors drive ERK phosphorylation and MCL1 expression to promote osteosarcoma cell survival during metastatic lung colonization
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    link.springer.com/article/10.1007/s13402-023-00867-w
  72. Jun 2023
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activating FcγR function depends on endosomal-signaling platforms
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    ncbi.nlm.nih.gov/pmc/articles/PMC10285637/
  74. May 2023
  75. elifesciences.org elifesciences.org
    pYtags enable spatiotemporal measurements of receptor tyrosine kinase signaling in living cells
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    elifesciences.org/articles/82863
  76. www.sciencedirect.com www.sciencedirect.com
    A costimulatory chimeric antigen receptor targeting TROP2 enhances the cytotoxicity of NK cells expressing a T cell receptor reactive to human papillomavirus type 16 E7
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    sciencedirect.com/science/article/pii/S0304383523001933
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Independent control over cell patterning and adhesion on hydrogel substrates for tissue interface mechanobiology
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    ncbi.nlm.nih.gov/pmc/articles/PMC10164898/
  78. Apr 2023
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Purinergic GPCR-integrin interactions drive pancreatic cancer cell invasion
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    ncbi.nlm.nih.gov/pmc/articles/PMC10069867/
  80. Oct 2022
  81. www.sciencedirect.com www.sciencedirect.com
    Competition for endothelial cell polarity drives vascular morphogenesis in the mouse retina
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    sciencedirect.com/science/article/pii/S1534580722006323
  82. Sep 2022
  83. www.sciencedirect.com www.sciencedirect.com
    Meteorin links the bone marrow hypoxic state to hematopoietic stem/progenitor cell mobilization
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    sciencedirect.com/science/article/pii/S2211124722011937
  84. Aug 2022
  85. www.sciencedirect.com www.sciencedirect.com
    Saturation of the mitochondrial NADH shuttles drives aerobic glycolysis in proliferating cells
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    sciencedirect.com/science/article/pii/S1097276522007031
  86. Jun 2022
  87. molecularneurodegeneration.biomedcentral.com molecularneurodegeneration.biomedcentral.com
    LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
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    molecularneurodegeneration.biomedcentral.com/articles/10.1186/s13024-022-00550-y
  88. May 2022
  89. www.sciencedirect.com www.sciencedirect.com
    HIV-1 exploits the Fanconi anemia pathway for viral DNA integration
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    sciencedirect.com/science/article/pii/S2211124722006131
  90. aacrjournals.org aacrjournals.org
    JNK signaling promotes bladder cancer immune escape by regulating METTL3-mediated m6A modification of PD-L1 mRNA
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    aacrjournals.org/cancerres/article/82/9/1789/694701/JNK-Signaling-Promotes-Bladder-Cancer-Immune
  91. Mar 2022
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    P2Y1 purinergic receptor identified as a diabetes target in a small-molecule screen to reverse circadian β-cell failure
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    ncbi.nlm.nih.gov/pmc/articles/PMC8860442/
  93. Feb 2022
  94. www.sciencedirect.com www.sciencedirect.com
    Enzymatic activity of glycosyltransferase GLT8D1 promotes human glioblastoma cell migration
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    sciencedirect.com/science/article/pii/S2589004222001122
  95. www.sciencedirect.com www.sciencedirect.com
    Phosphorylation of guanosine monophosphate reductase triggers a GTP-dependent switch from pro- to anti-oncogenic function of EPHA4
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    sciencedirect.com/science/article/pii/S2451945622000496
  96. Jan 2022
  97. www.sciencedirect.com www.sciencedirect.com
    TGF-β-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures
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    sciencedirect.com/science/article/pii/S1074761321005434
  98. Dec 2021
  99. www.sciencedirect.com www.sciencedirect.com
    Substratum stiffness regulates Erk signaling dynamics through receptor-level control
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    sciencedirect.com/science/article/pii/S2211124721016818
  100. link.springer.com link.springer.com
    Knockdown of Astrocytic Monocarboxylate Transporter 4 in the Motor Cortex Leads to Loss of Dendritic Spines and a Deficit in Motor Learning
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    link.springer.com/article/10.1007/s12035-021-02651-z
  101. Nov 2021
  102. www.sciencedirect.com www.sciencedirect.com
    A synthetic gene circuit for imaging-free detection of signaling pulses
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    sciencedirect.com/science/article/pii/S2405471221004130
  103. Aug 2021
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6251307/
  105. www.cell.com www.cell.com
    Untitled document
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    cell.com/cell-reports/abstract/S2211-1247(18)31443-8
  106. Jul 2021
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6351101/
  108. elifesciences.org elifesciences.org
    USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication
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    elifesciences.org/articles/48318
  109. www.sciencedirect.com www.sciencedirect.com
    Mapping Cellular Reprogramming via Pooled Overexpression Screens with Paired Fitness and Single-Cell RNA-Sequencing Readout
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    sciencedirect.com/science/article/pii/S2405471218304332
  110. Jun 2021
  111. www.sciencedirect.com www.sciencedirect.com
    Positive feedback between the T cell kinase Zap70 and its substrate LAT acts as a clustering-dependent signaling switch
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    sciencedirect.com/science/article/pii/S2211124721006471
  112. www.nature.com www.nature.com
    Targeted PI3K/AKT-hyperactivation induces cell death in chronic lymphocytic leukemia
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    nature.com/articles/s41467-021-23752-2
  113. May 2021
  114. www.sciencedirect.com www.sciencedirect.com
    Peptide-tiling screens of cancer drivers reveal oncogenic protein domains and associated peptide inhibitors
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    sciencedirect.com/science/article/pii/S2405471221001575
  115. www.sciencedirect.com www.sciencedirect.com
    Mechanical instability of adherens junctions overrides intrinsic quiescence of hair follicle stem cells
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    sciencedirect.com/science/article/pii/S153458072100160X
  116. Apr 2021
  117. www-sciencedirect-com.ezproxy.rice.edu www-sciencedirect-com.ezproxy.rice.edu
    Psychedelic-inspired drug discovery using an engineered biosensor
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    www-sciencedirect-com.ezproxy.rice.edu/science/article/pii/S0092867421003743
  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 protein subunit vaccination of mice and rhesus macaques elicits potent and durable neutralizing antibody responses
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    ncbi.nlm.nih.gov/pmc/articles/PMC8020888/
  119. Feb 2021
  120. www.sciencedirect.com www.sciencedirect.com
    Quantitative analysis of dense-core vesicle fusion in rodent CNS neurons
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    sciencedirect.com/science/article/pii/S2666166721000320
  121. Nov 2020
  122. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Real-Time Conformational Dynamics of SARS-CoV-2 Spikes on Virus Particles
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    pubmed.ncbi.nlm.nih.gov/33242391/
  123. Sep 2020
  124. onlinelibrary.wiley.com onlinelibrary.wiley.com
    FGF13 promotes metastasis of triple‐negative breast cancer
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32874
  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CtBP determines ovarian cancer cell fate through repression of death receptors
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    ncbi.nlm.nih.gov/pmc/articles/PMC7181866/
  126. link.springer.com link.springer.com
    Impaired differentiation of human induced neural stem cells by TOR1A overexpression
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    link.springer.com/article/10.1007/s11033-020-05390-x
  127. Jan 2020
  128. www.sciencedirect.com www.sciencedirect.com
    Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140
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    sciencedirect.com/science/article/pii/S0896627318308961
  129. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S1934590919300116
  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6351101/