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  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Soluble Tim-3 serves as a tumor prognostic marker and therapeutic target for CD8+ T cell exhaustion and anti-PD-1 resistance
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    1. scibot 25 Aug 2024
      plasmid_12371

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    sciencedirect.com/science/article/pii/S2666379124004075
  3. Aug 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A pathologically expanded, clonal lineage of IL-21–producing CD4+ T cells drives inflammatory neuropathy
    1
    1. scibot 18 Aug 2024
      12371

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    ncbi.nlm.nih.gov/pmc/articles/PMC11290969/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fructose vs. glucose: modulating stem cell growth and function through sugar supplementation
    1
    1. scibot 18 Aug 2024
      12371

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    ncbi.nlm.nih.gov/pmc/articles/PMC11301265/
  6. Jul 2024
  7. www.sciencedirect.com www.sciencedirect.com
    MicroRNA-19b exacerbates systemic sclerosis through promoting Th9 cells
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    1. scibot 31 Jul 2024
      RRID:Addgene_12371

      DOI: 10.1016/j.celrep.2024.114565

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    sciencedirect.com/science/article/pii/S2211124724008945
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    pLxIS-containing domains are biochemically flexible regulators of interferons and metabolism
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    1. scibot 23 Jul 2024
      RRID:Addgene_12371

      DOI: 10.1016/j.molcel.2024.05.030

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    sciencedirect.com/science/article/pii/S1097276524004775
  9. rupress.org rupress.org
    PD-L1 promotes oncolytic virus infection via a metabolic shift that inhibits the type I IFN pathway
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    1. scibot 18 Jul 2024
      RRID:Addgene_12371

      DOI: 10.1084/jem.20221721

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    rupress.org/jem/article/221/7/e20221721/276807/PD-L1-promotes-oncolytic-virus-infection-via-a
  10. Jun 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD52/FLAG and CD52/HA Fusion Proteins as Novel Magnetic Cell Selection Markers
    1
    1. scibot 30 Jun 2024
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      DOI: 10.3390/ijms25126353

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    ncbi.nlm.nih.gov/pmc/articles/PMC11203882/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC6 Inhibition Releases HR23B to Activate Proteasomes, Expand the Tumor Immunopeptidome and Amplify T-cell Antimyeloma Activity
    1
    1. scibot 27 Jun 2024
      RRID:Addgene_12371

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    ncbi.nlm.nih.gov/pmc/articles/PMC11188874/
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The DNA damage-independent ATM signalling maintains CBP/DOT1L axis in MLL rearranged acute myeloid leukaemia
    1
    1. scibot 20 Jun 2024
      plasmid_12371

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    ncbi.nlm.nih.gov/pmc/articles/PMC11178498/
  14. May 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cell of origin epigenetic priming determines susceptibility to Tet2 mutation
    1
    1. scibot 24 May 2024
      plasmid_12371

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    ncbi.nlm.nih.gov/pmc/articles/PMC11109152/
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    T-bet deficiency and Hic1 induction override TGF-β-dependency in the formation of CD103+ intestine-resident memory CD8+ T cells
    1
    1. scibot 23 May 2024
      RRID:Addgene_12371

      DOI: 10.1016/j.celrep.2024.114258

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    sciencedirect.com/science/article/pii/S2211124724005862
  17. www.sciencedirect.com www.sciencedirect.com
    Critical roles of the miR-17∼92 family in thymocyte development, leukemogenesis, and autoimmunity
    1
    1. scibot 23 May 2024
      RRID:Addgene_12371

      DOI: 10.1016/j.celrep.2024.114261

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    sciencedirect.com/science/article/pii/S2211124724005898
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    T cell help shapes B cell tolerance
    1
    1. scibot 19 May 2024
      12371

      DOI: 10.1126/sciimmunol.adj7029

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    ncbi.nlm.nih.gov/pmc/articles/PMC11095409/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oncogene EVI1 drives acute myeloid leukemia via a targetable interaction with CTBP2
    1
    1. scibot 19 May 2024
      12371

      DOI: 10.1126/sciadv.adk9076

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    ncbi.nlm.nih.gov/pmc/articles/PMC11095456/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting senescent cells with NKG2D-CAR T cells
    1
    1. scibot 12 May 2024
      12371

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    ncbi.nlm.nih.gov/pmc/articles/PMC11069534/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Perinuclear damage from nuclear envelope deterioration elicits stress responses that contribute to LMNA cardiomyopathy
    1
    1. scibot 12 May 2024
      12371

      DOI: 10.1126/sciadv.adh0798

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    ncbi.nlm.nih.gov/pmc/articles/PMC11078192/
  22. Apr 2024
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Recurrent mutations in tumor suppressor FBXW7 bypass Wnt/β-catenin addiction in cancer
    1
    1. scibot 14 Apr 2024
      12371

      DOI: 10.1126/sciadv.adk1031

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    ncbi.nlm.nih.gov/pmc/articles/PMC10990278/
  24. Mar 2024
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antigen-independent, autonomous B cell receptor signaling drives activated B cell DLBCL
    1
    1. scibot 27 Mar 2024
      RRID:Addgene_12371

      DOI: 10.1084/jem.20230941

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    ncbi.nlm.nih.gov/pmc/articles/PMC10959178/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis for self-discrimination by neoantigen-specific TCRs
    1
    1. scibot 17 Mar 2024
      Addgene_12371

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    ncbi.nlm.nih.gov/pmc/articles/PMC10924104/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3’-UTR and promoting Rag1 mRNA expression
    1
    1. scibot 16 Mar 2024
      12371

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    ncbi.nlm.nih.gov/pmc/articles/PMC10928157/
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    Multimodal stimulation screens reveal unique and shared genes limiting T cell fitness
    3
    1. scibot 15 Mar 2024
      RRID:Addgene_12371

      DOI: 10.1016/j.ccell.2024.02.016

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      RRID:Addgene_12371

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    sciencedirect.com/science/article/pii/S1535610824000606
  29. www.sciencedirect.com www.sciencedirect.com
    NR4a1/2 deletion promotes accumulation of TCF1+ stem-like precursors of exhausted CD8+ T cells in the tumor microenvironment
    2
    1. scibot 06 Mar 2024
      Plasmid_12371

      DOI: 10.1016/j.celrep.2024.113898

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      Plasmid_12371

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    sciencedirect.com/science/article/pii/S2211124724002262
  30. Feb 2024
  31. www.sciencedirect.com www.sciencedirect.com
    Suppression of the METTL3-m6A-integrin β1 axis by extracellular acidification impairs T cell infiltration and antitumor activity
    2
    1. scibot 21 Feb 2024
      RRID:Addgene_12371

      DOI: 10.1016/j.celrep.2024.113796

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    sciencedirect.com/science/article/pii/S2211124724001244
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A pathologically expanded, clonal lineage of IL-21 producing CD4+ T cells drives Inflammatory neuropathy
    1
    1. scibot 05 Feb 2024
      12371

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    ncbi.nlm.nih.gov/pmc/articles/PMC10802410/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The CUL5 E3 ligase complex negatively regulates central signaling pathways in CD8+ T cells
    1
    1. scibot 01 Feb 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10798966/
  34. Jan 2024
  35. www.nature.com www.nature.com
    CD8+ T cell metabolic flexibility elicited by CD28-ARS2 axis-driven alternative splicing of PKM supports antitumor immunity
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    1. scibot 20 Jan 2024
      RRID:Addgene_12371

      DOI: 10.1038/s41423-024-01124-2

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    nature.com/articles/s41423-024-01124-2
  36. Dec 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Highly cooperative chimeric super-SOX induces naive pluripotency across species
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    1. scibot 23 Dec 2023
      Addgene_12371

      DOI: 10.1016/j.stem.2023.11.010

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    sciencedirect.com/science/article/pii/S1934590923004022
  38. www.sciencedirect.com www.sciencedirect.com
    MHC class II regulation of CD8+ T cell tolerance and implications in autoimmunity and cancer immunotherapy
    1
    1. scibot 01 Dec 2023
      RRID:Addgene_12371

      DOI: 10.1016/j.celrep.2023.113452

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    sciencedirect.com/science/article/pii/S221112472301464X
  39. Nov 2023
  40. www.biorxiv.org www.biorxiv.org
    One infusion of engineered long-lasting and multifunctional T cells cures asthma in mice
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    1. scibot 17 Nov 2023
      Addgene_12371

      DOI: 10.1101/2023.11.06.565713

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    biorxiv.org/content/10.1101/2023.11.06.565713v1
  41. Oct 2023
  42. www.sciencedirect.com www.sciencedirect.com
    Myotube growth is associated with cancer-like metabolic reprogramming and is limited by phosphoglycerate dehydrogenase
    1
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      plasmid_12371

      DOI: 10.1016/j.yexcr.2023.113820

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    sciencedirect.com/science/article/pii/S0014482723003713
  43. 52.53.155.43 52.53.155.43
    Cell of origin epigenetic priming determines susceptibility to Tet2 mutation
    1
    1. scibot 20 Oct 2023
      RRID:Addgene_12371

      DOI: 10.1101/2023.09.04.556230

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    52.53.155.43/7552772d6831058dd86904edd1d771977789c7d8/2023.09.04.556230.full-html.html
  44. www.sciencedirect.com www.sciencedirect.com
    Progenitor-like exhausted SPRY1+CD8+ T cells potentiate responsiveness to neoadjuvant PD-1 blockade in esophageal squamous cell carcinoma
    2
    1. scibot 13 Oct 2023
      Addgene_12371

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    sciencedirect.com/science/article/pii/S1535610823003276
  45. Sep 2023
  46. www.sciencedirect.com www.sciencedirect.com
    TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal
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      RRID:Addgene_12371

      DOI: 10.1016/j.stem.2023.07.001

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    sciencedirect.com/science/article/pii/S1934590923002461
  47. www.sciencedirect.com www.sciencedirect.com
    CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax
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    sciencedirect.com/science/article/pii/S2211124723010951
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhancing CAR T-cell Therapy Using Fab-Based Constitutively Heterodimeric Cytokine Receptors
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      RRID:Addgene_12371

      DOI: 10.1158/2326-6066.CIR-22-0640

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    ncbi.nlm.nih.gov/pmc/articles/PMC10472109/
  49. www.sciencedirect.com www.sciencedirect.com
    Molecular, metabolic, and functional CD4 T cell paralysis in the lymph node impedes tumor control
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      plasmid# 12371

      DOI: 10.1016/j.celrep.2023.113047

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    sciencedirect.com/science/article/pii/S2211124723010586
  50. Aug 2023
  51. 52.53.155.43 52.53.155.43
    The miR-17∼92 miRNAs promote plasma cell differentiation by suppressing SOCS3-mediated NIK degradation
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      addgene_12371

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      addgene_12371

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    52.53.155.43/8a075ef675e11ca05cb4fe9fd629f036036ec570/PIIS2211124723009798-html.html
  52. Jul 2023
  53. www.sciencedirect.com www.sciencedirect.com
    Activation of GPR44 decreases severity of myeloid leukemia via specific targeting of leukemia initiating stem cells
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      DOI: 10.1016/j.celrep.2023.112794

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    sciencedirect.com/science/article/pii/S2211124723008057
  54. Jun 2023
  55. www.sciencedirect.com www.sciencedirect.com
    Systematic dissection of coordinated stromal remodeling identifies Sox10+ glial cells as a therapeutic target in myelofibrosis
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  56. May 2023
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional requirements for a Samd14-capping protein complex in stress erythropoiesis
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  58. Apr 2023
  59. www.biorxiv.org www.biorxiv.org
    Molecular, metabolic and functional CD4 T cell paralysis impedes tumor control
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    Inducing an oxidized redox-balance improves anti-tumor CD8+ T cell function
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  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel role of pre-replication complex component cell division cycle 6 in retinal neovascularization
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  62. Jan 2023
  63. www.sciencedirect.com www.sciencedirect.com
    Small intestine and colon tissue-resident memory CD8+ T cells exhibit molecular heterogeneity and differential dependence on Eomes
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    METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism
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  65. Dec 2022
  66. academic.oup.com academic.oup.com
    Heterogeneous nuclear ribonucleoprotein K is overexpressed in acute myeloid leukemia and causes myeloproliferation in mice via altered Runx1 splicing
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  67. Nov 2022
  68. www.sciencedirect.com www.sciencedirect.com
    Adenosine deaminase acting on RNA-1 is essential for early B lymphopoiesis
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  69. Oct 2022
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The proprotein convertase furin regulates the development of thymic epithelial cells to ensure central immune tolerance
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  71. Aug 2022
  72. www.sciencedirect.com www.sciencedirect.com
    METTL14-dependent m6A modification controls iNKT cell development and function
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  73. Jul 2022
  74. www.cell.com www.cell.com
    Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8+ T cells
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    Generation of hematopoietic lineage cell-specific chimeric mice using retrovirus-transduced fetal liver cells
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  76. Apr 2022
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of CDK4/6 promotes CD8 T cell memory formation
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  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MLL5 is involved in retinal photoreceptor maturation through facilitating CRX-mediated photoreceptor gene transactivation
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  79. Mar 2022
  80. www.sciencedirect.com www.sciencedirect.com
    Capybara: A computational tool to measure cell identity and fate transitions
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    Postnatal regulation of B-1a cell development and survival by the CIC-PER2-BHLHE41 axis
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    RIF1 acts in DNA repair through phosphopeptide recognition of 53BP1
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    MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape
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  84. Feb 2022
  85. www.sciencedirect.com www.sciencedirect.com
    The spliceosome component Usp39 controls B cell development by regulating immunoglobulin gene rearrangement
    2
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    An oncogenic enhancer encodes selective selenium dependency in AML
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  87. Jan 2022
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of positive and negative selection and TCR signaling during thymic T cell development by capicua
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  89. Dec 2021
  90. www.sciencedirect.com www.sciencedirect.com
    Genome-wide fitness gene identification reveals Roquin as a potent suppressor of CD8 T cell expansion and anti-tumor immunity
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    Knockdown of Astrocytic Monocarboxylate Transporter 4 in the Motor Cortex Leads to Loss of Dendritic Spines and a Deficit in Motor Learning
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  92. Sep 2021
  93. www.sciencedirect.com www.sciencedirect.com
    PD-1+ Tcf1+ CD8+ T cells from established chronic infection can form memory while retaining a stableimprint of persistent antigen exposure
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  94. Jul 2021
  95. www.biorxiv.org www.biorxiv.org
    MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia
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  96. www.sciencedirect.com www.sciencedirect.com
    Phosphoinositide Interactions Position cGAS at the Plasma Membrane to Ensure Efficient Distinction between Self- and Viral DNA
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  98. Jun 2021
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    Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome
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    Mammalian cells use the autophagy process to restrict avian influenza virus replication
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  101. May 2021
  102. www.mdpi.com www.mdpi.com
    The Lysine Methylase SMYD3 Modulates Mesendodermal Commitment during Development
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    PI5P4Ks drive metabolic homeostasis through peroxisome-mitochondria interplay
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      Addgene plasmid Cat # 12371

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  104. Mar 2021
  105. www.sciencedirect.com www.sciencedirect.com
    Male sex chromosomal complement exacerbates the pathogenicity of Th17 cells in a chronic model of central nervous system autoimmunity
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  106. Feb 2021
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    The TGF-β superfamily cytokine Activin-A is induced during autoimmune neuroinflammation and drives pathogenic Th17 cell differentiation
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    A Genome-wide CRISPR Screen Reveals a Role for the Non-Canonical Nucleosome-Remodeling BAF Complex in Foxp3 Expression and Regulatory T Cell Function
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  109. Oct 2020
  110. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment
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  111. Sep 2020
  112. www.sciencedirect.com www.sciencedirect.com
    Suppression of Inflammasome Activation by IRF8 and IRF4 in cDCs Is Critical for T Cell Priming
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  113. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Malignant Transformation Involving CXXC4 Mutations Identified in a Leukemic Progression Model of Severe Congenital Neutropenia
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  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated transcriptomic and epigenetic data analysis identifiesaberrant expression of genes in acute myeloid leukemia with MLL‑AF9 translocation
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  115. www.sciencedirect.com www.sciencedirect.com
    Targeting the PI5P4K Lipid Kinase Family in Cancer Using Covalent Inhibitors
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  116. Jan 2020
  117. www.sciencedirect.com www.sciencedirect.com
    53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination
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    sciencedirect.com/science/article/pii/S1097276519307294
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    1. scibot 12 Jan 2020
      plasmid_12371

      DOI: 10.1016/j.celrep.2018.11.101

      Resource: RRID:Addgene_12371

      Curator: @evieth

      SciCrunch record: plasmid_12371

      What is this?

      RRID:Addgene_12371 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124718319077