74 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Ultra-large Scale Virtual Screening Identifies a Small Molecule Inhibitor of the Wnt transporter WLS
    1
    1. scibot 18 Jul 2024
      RRID:Addgene_12456

      DOI: 10.1016/j.isci.2024.110454

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    sciencedirect.com/science/article/pii/S2589004224016791
  3. Jun 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-catenin mRNA encapsulated in SM-102 lipid nanoparticles enhances bone formation in a murine tibia fracture repair model
    1
    1. scibot 06 Jun 2024
      12456

      DOI: 10.1016/j.bioactmat.2024.05.020

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    ncbi.nlm.nih.gov/pmc/articles/PMC11145078/
  5. www.sciencedirect.com www.sciencedirect.com
    Interactions between genistein and Wnt pathway in colon adenocarcinoma and early embryos
    1
    1. scibot 04 Jun 2024
      RRID:Addgene_12456

      DOI: 10.1016/j.heliyon.2024.e32243

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    sciencedirect.com/science/article/pii/S2405844024082744
  6. May 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phloroglucinol Enhances Anagen Signaling and Alleviates H2O2-Induced Oxidative Stress in Human Dermal Papilla Cells
    1
    1. scibot 19 May 2024
      12456

      DOI: 10.4014/jmb.2311.11047

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    ncbi.nlm.nih.gov/pmc/articles/PMC11091678/
  8. 52.53.155.43 52.53.155.43
    Phenotype-specific melanoma uptake of fatty acid from human adipocytes activates AXL and CAV1-dependent β-catenin nuclear accumulation
    1
    1. scibot 04 May 2024
      Addgene_12456

      DOI: 10.1101/2024.01.21.576568

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    52.53.155.43/5631ba0ece03be5b6bc39fba9c8a58e52d07c519/2024.01.21.576568v1.full-html.html
  9. Apr 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The pRb/RBL2-E2F1/4-GCN5 axis regulates cancer stem cell formation and G0 phase entry/exit by paracrine mechanisms
    1
    1. scibot 30 Apr 2024
      RRID:Addgene_12456

      DOI: 10.1038/s41467-024-47680-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC11055877/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stromal cartilage oligomeric matrix protein as a tumorigenic driver in ovarian cancer via Notch3 signaling and epithelial-to-mesenchymal transition
    1
    1. scibot 23 Apr 2024
      12456

      DOI: 10.1186/s12967-024-05083-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC11016227/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Competence for neural crest induction is controlled by hydrostatic pressure through Yap
    1
    1. scibot 23 Apr 2024
      12456

      DOI: 10.1038/s41556-024-01378-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC11021196/
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transport of CLCA2 to the nucleus by extracellular vesicles controls keratinocyte survival and migration
    1
    1. scibot 13 Apr 2024
      RRID:Addgene_12456

      DOI: 10.1002/jev2.12430

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    ncbi.nlm.nih.gov/pmc/articles/PMC11007793/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting CD73 with flavonoids inhibits cancer stem cells and increases lymphocyte infiltration in a triple-negative breast cancer mouse model
    1
    1. scibot 13 Apr 2024
      Plasmid_12456

      DOI: 10.3389/fimmu.2024.1366197

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    ncbi.nlm.nih.gov/pmc/articles/PMC11004431/
  15. Mar 2024
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TGFβ-induced long non-coding RNA LINC00313 activates Wnt signaling and promotes cholangiocarcinoma
    1
    1. scibot 15 Mar 2024
      plasmid_12456

      DOI: 10.1038/s44319-024-00075-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC10933437/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The co-receptor Tspan12 directly captures Norrin to promote ligand-specific β-catenin signaling
    1
    1. scibot 02 Mar 2024
      plasmid_12456

      DOI: 10.1101/2024.02.03.578714

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    ncbi.nlm.nih.gov/pmc/articles/PMC10862866/
  18. Feb 2024
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A genome-wide screen links peroxisome regulation with Wnt signaling through RNF146 and tankyrase
    1
    1. scibot 29 Feb 2024
      Addgene_12456

      DOI: 10.1101/2024.02.02.578667

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    ncbi.nlm.nih.gov/pmc/articles/PMC10862876/
  20. www.biorxiv.org www.biorxiv.org
    The Developmental Transcription Factor TBX3 Physically Engages with the Wnt/β-catenin Transcriptional Complex in Human Colorectal Cancer Cells to Regulate Metastasis Genes
    1
    1. scibot 15 Feb 2024
      Plasmid_12456

      DOI: 10.1101/2023.12.18.571901

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    biorxiv.org/content/10.1101/2023.12.18.571901v1
  21. www.sciencedirect.com www.sciencedirect.com
    Quantitative and qualitative mutational impact of ionizing radiation on normal cells
    1
    1. scibot 15 Feb 2024
      plasmid_12456

      DOI: 10.1016/j.xgen.2024.100499

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    sciencedirect.com/science/article/pii/S2666979X24000260
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LASS2 enhances chemosensitivity to cisplatin by inhibiting PP2A-mediated β-catenin dephosphorylation in a subset of stem-like bladder cancer cells
    1
    1. scibot 08 Feb 2024
      12456

      DOI: 10.1186/s12916-023-03243-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC10775422/
  23. Jan 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Programmable RNA base editing with photoactivatable CRISPR-Cas13
    1
    1. scibot 30 Jan 2024
      Addgene plasmid 12456

      DOI: 10.1038/s41467-024-44867-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC10803366/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sumoylation of SAP130 regulates its interaction with FAF1 as well as its protein stability and transcriptional repressor function
    1
    1. scibot 10 Jan 2024
      RRID:Addgene_12456

      DOI: 10.1186/s12860-023-00498-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC10765799/
  26. Nov 2023
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The PMA phorbol ester tumor promoter increases canonical Wnt signaling via macropinocytosis
    1
    1. scibot 02 Nov 2023
      RRID:Addgene_12456

      DOI: 10.7554/eLife.89141

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    ncbi.nlm.nih.gov/pmc/articles/PMC10615368/
  28. Oct 2023
  29. www.sciencedirect.com www.sciencedirect.com
    Addition of exogenous diacylglycerol enhances Wnt/β-catenin signaling through stimulation of macropinocytosis
    1
    1. scibot 14 Oct 2023
      RRID:Addgene_12456

      DOI: 10.1016/j.isci.2023.108075

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    sciencedirect.com/science/article/pii/S2589004223021521
  30. Sep 2023
  31. www.sciencedirect.com www.sciencedirect.com
    Modulation of cell physiology by bispecific nanobodies enabling changes in the intracellular localization of organelle proteins
    1
    1. scibot 27 Sep 2023
      RRID:Addgene_12456

      DOI: 10.1016/j.bcp.2023.115708

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    sciencedirect.com/science/article/pii/S000629522300299X
  32. Aug 2023
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aicardi Syndrome Is a Genetically Heterogeneous Disorder
    1
    1. scibot 29 Aug 2023
      RRID:Addgene_12456

      DOI: 10.3390/genes14081565

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    ncbi.nlm.nih.gov/pmc/articles/PMC10454071/
  34. Jul 2023
  35. www.biorxiv.org www.biorxiv.org
    The PMA Phorbol Ester Tumor Promoter Increases Canonical Wnt Signaling Via Macropinocytosis
    1
    1. scibot 18 Jul 2023
      RRID:Addgene_124

      DOI: 10.1101/2023.06.02.543509

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    biorxiv.org/content/10.1101/2023.06.02.543509v2
  36. Jun 2023
  37. 52.53.155.43 52.53.155.43
    bqad096-html.html
    1
    1. scibot 25 Jun 2023
      RRID:Addgene_12456

      DOI: 10.1210/endocr/bqad096

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    52.53.155.43/a0f6dfb55e5b40d099e857f8219485820662af48/bqad096-html.html
  38. May 2023
  39. bioone.org bioone.org
    Activated Beta-Catenin Signaling Ameliorates Radiation-Induced Skin Injury by Suppressing Marvel D3 Expression
    1
    1. scibot 13 May 2023
      RRID:Addgene_12456

      DOI: 10.1667/RADE-20-00050.1

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    bioone.org/journals/radiation-research/volume-195/issue-2/RADE-20-00050.1/Activated-Beta-Catenin-Signaling-Ameliorates-Radiation-Induced-Skin-Injury-by/10.1667/RADE-20-00050.1.full
  40. Apr 2023
  41. www.biorxiv.org www.biorxiv.org
    Combination CDC-like kinase inhibition (CLK)/Dual-specificity tyrosine-regulated kinase (DYRK) and taxane therapy in CTNNB1-mutated endometrial cancer
    1
    1. scibot 20 Apr 2023
      RRID:Addgene_12456

      DOI: 10.1101/2023.04.04.535570

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    biorxiv.org/content/10.1101/2023.04.04.535570v1
  42. Mar 2023
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The biotoxin BMAA promotes dysfunction via distinct mechanisms in neuroblastoma and glioblastoma cells
    1
    1. scibot 13 Mar 2023
      RRID:Addgene_12456

      DOI: 10.1371/journal.pone.0278793

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    ncbi.nlm.nih.gov/pmc/articles/PMC9997973/
  44. Feb 2023
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Quantitative trait loci on chromosomes 9 and 19 modulate AII amacrine cell number in the mouse retina
    1
    1. scibot 19 Feb 2023
      RRID:Addgene_12456

      DOI: 10.3389/fnins.2023.1078168

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    ncbi.nlm.nih.gov/pmc/articles/PMC9932814/
  46. Jan 2023
  47. www.sciencedirect.com www.sciencedirect.com
    Dual-specificity RNA aptamers enable manipulation of target-specific O-GlcNAcylation and unveil functions of O-GlcNAc on β-catenin
    1
    1. scibot 28 Jan 2023
      RRID: Addgene_12456

      DOI: 10.1016/j.cell.2022.12.016

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    sciencedirect.com/science/article/pii/S009286742201529X
  48. Nov 2022
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    R-spondin 3 deletion induces Erk phosphorylation to enhance Wnt signaling and promote bone formation in the appendicular skeleton
    1
    1. scibot 30 Nov 2022
      RRID:Addgene_12456

      DOI: 10.7554/eLife.84171

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    ncbi.nlm.nih.gov/pmc/articles/PMC9681208/
  50. Oct 2022
  51. www.nature.com www.nature.com
    DNA methyltransferase 3A controls intestinal epithelial barrier function and regeneration in the colon
    1
    1. scibot 22 Oct 2022
      RRID:Addgene_12456

      DOI: 10.1038/s41467-022-33844-2

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    nature.com/articles/s41467-022-33844-2
  52. www.science.org www.science.org
    PI(4,5)P 2-stimulated positive feedback drives the recruitment of Dishevelled to Frizzled in Wnt-β-catenin signaling
    1
    1. scibot 08 Oct 2022
      plasmid_12456

      DOI: 10.1126/scisignal.abo2820

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    science.org/doi/10.1126/scisignal.abo2820
  53. Sep 2022
  54. www.sciencedirect.com www.sciencedirect.com
    Genomic and phenotypic characterization of 404 individuals with neurodevelopmental disorders caused by CTNNB1 variants
    1
    1. scibot 14 Sep 2022
      RRID:Addgene_12456

      DOI: 10.1016/j.gim.2022.08.006

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    sciencedirect.com/science/article/pii/S1098360022008978
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optogenetic control of the canonical Wnt signaling pathway during Xenopus laevis embryonic development
    1
    1. scibot 08 Sep 2022
      RRID:Addgene_12456

      DOI: 10.1016/j.jmb.2021.167050

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    ncbi.nlm.nih.gov/pmc/articles/PMC8380706/
  56. May 2022
  57. www.sciencedirect.com www.sciencedirect.com
    5-hydroxytryptamine produced by enteric serotonergic neurons initiates colorectal cancer stem cell self-renewal and tumorigenesis
    1
    1. scibot 13 May 2022
      Plasmid_12456

      DOI: 10.1016/j.neuron.2022.04.024

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    sciencedirect.com/science/article/pii/S0896627322003695
  58. www.nature.com www.nature.com
    Transcription Factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron content
    1
    1. scibot 03 May 2022
      RRID:Addgene_12456

      DOI: 10.1038/s41467-022-29942-w

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    nature.com/articles/s41467-022-29942-w
  59. Apr 2022
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Canonical Wnt Signaling Induces Focal Adhesion and Integrin Beta-1 Endocytosis
    1
    1. scibot 09 Apr 2022
      RRID:Addgene_12456

      DOI: 10.1016/j.isci.2022.104123

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    ncbi.nlm.nih.gov/pmc/articles/PMC8987407/
  61. Mar 2022
  62. www.sciencedirect.com www.sciencedirect.com
    Neddylation is essential for β-catenin degradation in Wnt signaling pathway
    1
    1. scibot 23 Mar 2022
      plasmid_12456

      DOI: 10.1016/j.celrep.2022.110538

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    sciencedirect.com/science/article/pii/S2211124722002790
  63. www.sciencedirect.com www.sciencedirect.com
    Ivermectin represses Wnt/β-catenin signaling by binding to TELO2, a regulator of phosphatidylinositol 3-kinase-related kinases
    1
    1. scibot 09 Mar 2022
      AddgeneCat# 12456

      DOI: 10.1016/j.isci.2022.103912

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    sciencedirect.com/science/article/pii/S2589004222001821
  64. link.springer.com link.springer.com
    Muscle Stem Cell Function Is Impaired in β2-Adrenoceptor Knockout Mice
    2
    1. scibot 05 Mar 2022
      plasmid_12456

      DOI: 10.1007/s12015-022-10334-y

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    2. scibot 05 Mar 2022
      RRID:Addgene_12

      DOI: 10.1007/s12015-022-10334-y

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    link.springer.com/article/10.1007/s12015-022-10334-y
  65. Feb 2022
  66. www.sciencedirect.com www.sciencedirect.com
    Liquidambaric acid inhibits Wnt/β-catenin signaling and colon cancer via targeting TNF receptor-associated factor 2
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    1. scibot 02 Feb 2022
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    sciencedirect.com/science/article/pii/S2211124722000304
  67. link.springer.com link.springer.com
    Competitive blocking of LRP4–sclerostin binding interface strongly promotes bone anabolic functions
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  68. Jan 2022
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evidence for a Dual-Pathway, 2-Hit Genetic Model for Focal Cortical Dysplasia and Epilepsy
    1
    1. scibot 29 Jan 2022
      RRID:Addgene_12456

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    ncbi.nlm.nih.gov/pmc/articles/PMC8789218/
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel C-terminal heat shock protein 90 inhibitor that overcomes STAT3-Wnt-β-catenin signaling-mediated drug resistance and adverse effects
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    1. scibot 05 Jan 2022
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      DOI: 10.7150/thno.63788

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    ncbi.nlm.nih.gov/pmc/articles/PMC8690924/
  71. Oct 2021
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures
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    1. scibot 02 Oct 2021
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    ncbi.nlm.nih.gov/pmc/articles/PMC8480975/
  73. Sep 2021
  74. www.nature.com www.nature.com
    Compact RNA editors with small Cas13 proteins
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    1. scibot 22 Sep 2021
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    nature.com/articles/s41587-021-01030-2
  75. Aug 2021
  76. www.sciencedirect.com www.sciencedirect.com
    Antagonistic interactions between osterix and pyrophosphate during cementum formation
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    sciencedirect.com/science/article/pii/S8756328219301656
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RAL GTPases Drive Intestinal Stem Cell Function and Regeneration through Internalization of WNT Signalosomes
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  78. Jul 2021
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  80. www.sciencedirect.com www.sciencedirect.com
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  81. www.nature.com www.nature.com
    Vps11 and Vps18 of Vps-C membrane traffic complexes are E3 ubiquitin ligases and fine-tune signalling
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    1. scibot 28 Jul 2021
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  82. academic.oup.com academic.oup.com
    Downregulation of ARID1B, a tumor-suppressor in the WNT subgroup medulloblastoma, activates multiple oncogenic signaling pathways
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    academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddab134/6265029
  83. May 2021
  84. link.springer.com link.springer.com
    miR-637 Prevents Glioblastoma Progression by Interrupting ZEB2/WNT/β-catenin Cascades
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  85. www.sciencedirect.com www.sciencedirect.com
    Derivation of Intermediate Pluripotent Stem Cells Amenable to Primordial Germ Cell Specification
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    sciencedirect.com/science/article/pii/S1934590920305415
  86. Apr 2021
  87. www.sciencedirect.com www.sciencedirect.com
    Modulation of lanosterol synthase drives 24,25-epoxysterol synthesis and oligodendrocyte formation
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    sciencedirect.com/science/article/pii/S2451945621000519
  88. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Reduced RECK levels accelerate skeletal muscle differentiation, improve muscle regeneration, and decrease fibrosis
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    faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202001646RR
  89. Feb 2021
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective activation of FZD7 promotes mesendodermal differentiation of human pluripotent stem cells
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  91. www.sciencedirect.com www.sciencedirect.com
    Structural Basis of WLS/Evi-Mediated Wnt Transport and Secretion
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    sciencedirect.com/science/article/pii/S009286742031610X
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-Catenin inhibition shapes tumor immunity and synergizes with immunotherapy in colorectal cancer
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  93. www.sciencedirect.com www.sciencedirect.com
    GSK3 Inhibits Macropinocytosis and Lysosomal Activity through the Wnt Destruction Complex Machinery
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      RRID:Addgene_12456

      DOI: 10.1016/j.celrep.2020.107973

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    sciencedirect.com/science/article/pii/S2211124720309542
  94. www.sciencedirect.com www.sciencedirect.com
    Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase
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      RRID:Addgene_12456

      DOI: 10.1016/j.celrep.2020.107922

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    sciencedirect.com/science/article/pii/S2211124720309037
  95. Oct 2020
  96. www.sciencedirect.com www.sciencedirect.com
    Identification of Fibroblast Activation Protein as an Osteogenic Suppressor and Anti-osteoporosis Drug Target
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    1. scibot 17 Oct 2020
      RRID:Addgene_12456

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    sciencedirect.com/science/article/pii/S2211124720312419
  97. Sep 2020
  98. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Naive Pluripotent Stem Cells Exhibit Phenotypic Variability that Is Driven by Genetic Variation
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      RRID:Addgene_12456

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  99. www.mdpi.com www.mdpi.com
    Obatoclax, a Pan-BCL-2 Inhibitor, Downregulates Survivin to Induce Apoptosis in Human Colorectal Carcinoma Cells Via Suppressing WNT/β-catenin Signaling
    1
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      RRID:Addgene_12456

      DOI: 10.3390/ijms21051773

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    mdpi.com/1422-0067/21/5/1773
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin
    1
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      DOI: 10.7554/eLife.52779

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  101. journals.plos.org journals.plos.org
    Morphine exposure exacerbates HIV-1 Tat driven changes to neuroinflammatory factors in cultured astrocytes
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      RRID:Addgene_12456

      DOI: 10.1371/journal.pone.0230563

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  102. www.sciencedirect.com www.sciencedirect.com
    Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription
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      Addgene #12456

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  103. Jan 2020
  104. elifesciences.org elifesciences.org
    Mutationally-activated PI3’-kinase-α promotes de-differentiation of lung tumors initiated by the BRAFV600E oncoprotein kinase
    1
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      RRID:Addgene_12456

      DOI: 10.7554/eLife.43668

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    elifesciences.org/articles/43668
  105. elifesciences.org elifesciences.org
    FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy
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      Plasmid_12456

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  106. www.oncotarget.com www.oncotarget.com
    Oncotarget | Targeting transcription factor TCF4 by γ-Mangostin, a natural xanthone
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      RRID:Addgene_12456

      DOI: 10.18632/oncotarget.27159

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  107. wellcomeopenresearch.org wellcomeopenresearch.org
    Pathogenic <i>FAM83G</i> palmoplantar keratoderma mutations inhibit the PAWS1:CK1α association and attenuate Wnt signalling.
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      DOI: 10.12688/wellcomeopenres.15403.1

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  108. www.sciencedirect.com www.sciencedirect.com
    Small Heterodimer Partner Controls the Virus-Mediated Antiviral Immune Response by Targeting CREB-Binding Protein in the Nucleus
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      DOI: 10.1016/j.celrep.2019.04.071

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  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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