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pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis

1
1. scibot 29 Mar 2026
  
  in Public
  
  Addgene_127968
  
  DOI: 10.1016/j.cell.2025.12.038
  
  Resource: RRID:Addgene_127968
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_127968
  
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  RRID:Addgene_127968
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pmc.ncbi.nlm.nih.gov/articles/PMC12978015/
Feb 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Mapping cis- and trans-regulatory target genes of human-specific deletions

1
1. scibot 01 Feb 2026
  
  in Public
  
  127968
  
  DOI: 10.1038/s41467-025-67424-x
  
  Resource: RRID:Addgene_127968
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_127968
  
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  RRID:Addgene_127968
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RRID:Addgene_127968

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12727812/
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Core passive and facultative mTOR-mediated mechanisms coordinate mammalian protein synthesis and decay

1
1. scibot 23 Dec 2025
  
  in Public
  
  Plasmid_127968
  
  DOI: 10.1016/j.cels.2025.101456
  
  Resource: RRID:Addgene_127968
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_127968
  
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  RRID:Addgene_127968
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scibot

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sciencedirect.com:5037/science/article/pii/S2405471225002893
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

RNA-binding proteins DND1 and NANOS3 cooperatively suppress the entry of germ cell lineage

1
1. scibot 15 Jun 2025
  
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  127968
  
  DOI: 10.1038/s41467-025-57490-6
  
  Resource: RRID:Addgene_127968
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_127968
  
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  RRID:Addgene_127968
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RRID:Addgene_127968

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12102168/
May 2025
www.sciencedirect.com www.sciencedirect.com

IGF2BP1 restricts the induction of human primordial germ cell fate in an m6A-dependent manner

1
1. scibot 29 May 2025
  
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  RRID:Addgene_127968
  
  DOI: 10.1016/j.stem.2025.05.001
  
  Resource: RRID:Addgene_127968
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_127968
  
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  RRID:Addgene_127968
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sciencedirect.com/science/article/pii/S193459092500181X
Mar 2025
www.nature.com www.nature.com

Comparative characterization of human accelerated regions in neurons

1
1. scibot 07 Mar 2025
  
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  127968, Addgene
  
  DOI: 10.1038/s41586-025-08622-x
  
  Resource: RRID:Addgene_127968
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:Addgene_127968
  
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  RRID:Addgene_127968
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nature.com/articles/s41586-025-08622-x
Feb 2025
link.springer.com link.springer.com

Functional analysis of cancer-associated germline risk variants

1
1. scibot 20 Feb 2025
  
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  RRID:Addgene_127968
  
  DOI: 10.1038/s41588-024-02070-5
  
  Resource: RRID:Addgene_127968
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_127968
  
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  RRID:Addgene_127968
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link.springer.com/article/10.1038/s41588-024-02070-5
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Therapeutic validation of MMR-associated genetic modifiers in a human ex vivo model of Huntington disease

1
1. scibot 20 Jun 2024
  
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  addgene_12796849
  
  DOI: 10.1016/j.ajhg.2024.04.015
  
  Resource: RRID:Addgene_127968
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_127968
  
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  RRID:Addgene_127968 RRIDCUR:Incorrect RRIDCUR:Unresolved
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RRIDCUR:Incorrect

RRID:Addgene_127968

RRIDCUR:Unresolved

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11179424/
Apr 2024
www.sciencedirect.com www.sciencedirect.com

Human iPSC 4R tauopathy model uncovers modifiers of tau propagation

1
1. scibot 09 Apr 2024
  
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  Addgene_127968
  
  DOI: 10.1016/j.cell.2024.03.015
  
  Resource: RRID:Addgene_127968
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_127968
  
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  RRID:Addgene_127968
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scibot

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sciencedirect.com/science/article/pii/S0092867424003064
Jun 2023
www.sciencedirect.com www.sciencedirect.com

Comparative landscape of genetic dependencies in human and chimpanzee stem cells

1
1. scibot 21 Jun 2023
  
  in Public
  
  Addgene_127968
  
  DOI: 10.1016/j.cell.2023.05.043
  
  Resource: RRID:Addgene_127968
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_127968
  
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  RRID:Addgene_127968
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sciencedirect.com/science/article/pii/S0092867423005950
May 2023
www.biorxiv.org www.biorxiv.org

Comparative landscape of genetic dependencies in human and chimpanzee stem cells

1
1. scibot 04 May 2023
  
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  Addgene_127968
  
  DOI: 10.1101/2023.03.19.533346
  
  Resource: RRID:Addgene_127968
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_127968
  
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  RRID:Addgene_127968
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RRID:Addgene_127968

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scibot

URL

biorxiv.org/content/10.1101/2023.03.19.533346v1