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  1. Last 7 days
  2. www.nature.com www.nature.com
    Precise kilobase-scale genomic insertions in mammalian cells using PASTE
    2
    1. scibot 17 Dec 2024
      Addgene ID: 132777

      DOI: 10.1038/s41596-024-01090-z

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    2. scibot 17 Dec 2024
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      DOI: 10.1038/s41596-024-01090-z

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    nature.com/articles/s41596-024-01090-z
  3. Sep 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ISGylation enhances dsRNA-induced interferon response and NFκB signaling in fallopian tube epithelial cells
    1
    1. scibot 27 Sep 2024
      132777

      DOI: 10.1016/j.jbc.2024.107686

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    ncbi.nlm.nih.gov/pmc/articles/PMC11418117/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Engineering Oncogenic Hotspot Mutations on SF3B1 via CRISPR-Directed PRECIS Mutagenesis
    1
    1. scibot 27 Sep 2024
      132777

      DOI: 10.1158/2767-9764.CRC-24-0145

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    ncbi.nlm.nih.gov/pmc/articles/PMC11421219/
  6. www.sciencedirect.com www.sciencedirect.com
    Modeling the atrioventricular conduction axis using human pluripotent stem cell-derived cardiac assembloids
    1
    1. scibot 11 Sep 2024
      RRID:Addgene_132777

      DOI: 10.1016/j.stem.2024.08.008

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    sciencedirect.com/science/article/pii/S1934590924002947
  7. Aug 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Directed evolution of hyperactive integrases for site specific insertion of transgenes
    1
    1. scibot 22 Aug 2024
      Addgene_132777

      DOI: 10.1093/nar/gkae534

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    ncbi.nlm.nih.gov/pmc/articles/PMC11317131/
  9. Jun 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Precise editing of pathogenic nucleotide repeat expansions in iPSCs using paired prime editor
    1
    1. scibot 15 Jun 2024
      plasmid_132777

      DOI: 10.1093/nar/gkae310

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    ncbi.nlm.nih.gov/pmc/articles/PMC11162781/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Application of prime editing system to introduce TP53 R248Q hotspot mutation in acute lymphoblastic leukemia cell line
    1
    1. scibot 06 Jun 2024
      132777

      DOI: 10.1111/cas.16162

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    ncbi.nlm.nih.gov/pmc/articles/PMC11145152/
  12. May 2024
  13. www.biorxiv.org www.biorxiv.org
    Enrichment of allelic editing outcomes by Prime Editing in iPS cells
    1
    1. scibot 29 May 2024
      RRID; Addgene_132777

      DOI: 10.1101/2024.03.19.585665

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    biorxiv.org/content/10.1101/2024.03.19.585665v1
  14. analyticalsciencejournals.onlinelibrary.wiley.com analyticalsciencejournals.onlinelibrary.wiley.com
    Prime editing-mediated correction of the leptin receptor in muscle cells of db/db mice
    1
    1. scibot 16 May 2024
      RRID:Addgene_132777

      DOI: 10.1002/biot.202300676

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    analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/biot.202300676
  15. www.sciencedirect.com www.sciencedirect.com
    Prime editing functionally corrects cystic fibrosis-causing CFTR mutations in human organoids and airway epithelial cells
    1
    1. scibot 02 May 2024
      Addgene: 132777

      DOI: 10.1016/j.xcrm.2024.101544

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    sciencedirect.com/science/article/pii/S2666379124002349
  16. Apr 2024
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Improving prime editing with an endogenous small RNA-binding protein
    1
    1. scibot 23 Apr 2024
      132777

      DOI: 10.1038/s41586-024-07259-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC11023932/
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Massively parallel screen uncovers many rare 3′ UTR variants regulating mRNA abundance of cancer driver genes
    1
    1. scibot 23 Apr 2024
      Plasmid_132777

      DOI: 10.1038/s41467-024-46795-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC11026479/
  19. Feb 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation of Human Isogenic Induced Pluripotent Stem Cell Lines with CRISPR Prime Editing
    1
    1. scibot 29 Feb 2024
      Addgene_132777

      DOI: 10.1089/crispr.2023.0066

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    ncbi.nlm.nih.gov/pmc/articles/PMC10880268/
  21. www.biorxiv.org www.biorxiv.org
    iSCORE-PD: an isogenic stem cell collection to research Parkinson’s Disease
    1
    1. scibot 22 Feb 2024
      RRID:Addgene_132777

      DOI: 10.1101/2024.02.12.579917

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    biorxiv.org/content/10.1101/2024.02.12.579917v1
  22. Sep 2023
  23. www.nature.com www.nature.com
    CRISPR prime editing for unconstrained correction of oncogenic KRAS variants
    1
    1. scibot 20 Sep 2023
      132777

      DOI: 10.1038/s42003-023-05052-1

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    nature.com/articles/s42003-023-05052-1
  24. May 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Generation of three CRISPR/Cas9 edited human induced pluripotent stem cell lines (DHMi005-A-5, DHMi005-A-6 and DHMi005-A-7) carrying a Holt-Oram Syndrome patient-specific TBX5 mutation with known cardiac phenotype and a FLAG-tag after exon 9 of the TBX5 gene
    1
    1. scibot 17 May 2023
      Addgene_132777

      DOI: 10.1016/j.scr.2023.103123

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    sciencedirect.com/science/article/pii/S1873506123001095
  26. Apr 2023
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An OMA1 redox site controls mitochondrial homeostasis, sarcoma growth, and immunogenicity
    1
    1. scibot 08 Apr 2023
      RRID:Addgene_132777

      DOI: 10.26508/lsa.202201767

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    ncbi.nlm.nih.gov/pmc/articles/PMC10078952/
  28. Oct 2022
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Highly efficient generation of isogenic pluripotent stem cell models using prime editing
    1
    1. scibot 25 Oct 2022
      RRID:Addgene_132777

      DOI: 10.7554/eLife.79208

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    ncbi.nlm.nih.gov/pmc/articles/PMC9584603/
  30. www.sciencedirect.com www.sciencedirect.com
    Histone methylation antagonism drives tumor immune evasion in squamous cell carcinomas
    1
    1. scibot 07 Oct 2022
      Cat#132777

      DOI: 10.1016/j.molcel.2022.09.007

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      Curator: @a5munoz

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    sciencedirect.com/science/article/pii/S1097276522008966
  31. May 2022
  32. www.sciencedirect.com www.sciencedirect.com
    A PARylation-phosphorylation cascade promotes TOPBP1 loading and RPA-RAD51 exchange in homologous recombination
    1
    1. scibot 25 May 2022
      AddgeneCat#132777

      DOI: 10.1016/j.molcel.2022.04.031

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      Curator: @sophiastull

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    sciencedirect.com/science/article/pii/S109727652200394X
  33. www.nature.com www.nature.com
    Saturation variant interpretation using CRISPR prime editing
    1
    1. scibot 05 May 2022
      RRID:Addgene_132777

      DOI: 10.1038/s41587-021-01201-1

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    nature.com/articles/s41587-021-01201-1
  34. Jan 2022
  35. www.sciencedirect.com www.sciencedirect.com
    Generation of a CRISPR/Cas edited human induced pluripotent stem cell line DHMi005-A-1 carrying a patient-specific disease-causing point mutation in the TBX5 gene
    2
    1. scibot 28 Jan 2022
      Addgene #132777

      DOI: 10.1016/j.scr.2022.102691

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    2. scibot 28 Jan 2022
      RRID:Addgene_132777

      DOI: 10.1016/j.scr.2022.102691

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    sciencedirect.com/science/article/pii/S187350612200040X
  36. May 2021
  37. www.sciencedirect.com www.sciencedirect.com
    Adenine base editing and prime editing of chemically derived hepatic progenitors rescue genetic liver disease
    1
    1. scibot 05 May 2021
      Addgene_132777

      DOI: 10.1016/j.stem.2021.04.010

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    sciencedirect.com/science/article/pii/S1934590921001673