92 Matching Annotations
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    Pulmonary surfactant protein D reduces lung cancer progression associated with decreased IL-4/STAT6 signaling
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    Tuning the sensitivity of mechanosensory receptors through histidine scanning
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  4. Mar 2026
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    Perturb-seq uncovers pathological obstacles to direct cardiac reprogramming in vivo
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    HE4 drives PD-L1 expression in myeloid cells via IFN-γR-JAK-STAT3 signaling to promote tumor immune evasion
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    Differential AXL expression and Arf1 regulation control stiffness-dependent Golgi organization in breast cancer cells
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    Intratumoral microbiota and host genotype cooperatively shape neutrophil cytotoxic functions in colorectal cancer
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    Targeting PGAM5-driven mitochondrial integrated stress response slows ALS progression across subtypes
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  10. Jan 2026
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    Angiotensin II type 1 receptor signaling promotes bladder cancer progression and its inhibition by Losartan
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    BCLAF1 links RNA splicing to ATF4-dependent metabolic adaptation in acute myeloid leukemia
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    Pan-cancer N-glycoproteomic atlas of patient-derived xenografts uncovers FAT2 as an actionable surface target
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  14. Dec 2025
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    SLFN14 functions as a P-TEFb inhibitor to modulate the transcription of HIV-1 and cellular genes
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    Photo-proximity labeling in live primary neurons identifies an AMPA-receptor signal transducer in homeostatic synaptic plasticity
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    Crucial Contribution of BACH1 to Bladder Cancer Progression via Upregulating Epithelial-Mesenchymal Transition Pathway
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  18. Nov 2025
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    Deciphering the epigenetic role of KDM4A in pancreatic β-like cell differentiation from iPSCs
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    MT1-MMP inhibition rejuvenates ageing brain and rescues cognitive deficits in obesity
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    NRCAM variant defined by microexon skipping is a targetable cell surface proteoform in high-grade gliomas
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    Prematurely Aged Human Microglia Exhibit Impaired Stress Response and Defective Nucleocytoplasmic Shuttling of ALS Associated FUS
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    PI5P4Kα promotes glucose and iron acquisition to support metabolic fitness in pancreatic cancer
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  24. Oct 2025
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    Arsenic regulates ALKBH1 abundance and substrate specificity to promote translation and tumorigenicity
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    SH2-mediated steric occlusion of the C2 domain regulates autoinhibition of SHIP1 inositol 5-phosphatase
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    Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer
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  30. Aug 2025
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    An EGFR Co-Amplified and De Novo Long Noncoding RNA HELDR Promotes Glioblastoma Malignancy through KAT7-Driven Gene Programs
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    A Four Amino Acid Intracellular Motif of VISTA Blocks Growth Receptor Signaling in Cancer Cells to Induce Tumor Suppression
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  33. Jul 2025
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    Nectin-4 expression in upper and lower tract urothelial carcinoma: correlation with early-stage disease and prognostic relevance
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  35. Jun 2025
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    An integrated proteomic portrait of prostate cancer progression
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    HSF1 remodels mitochondrial biogenesis and function in cancer cells via TIMM17A
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    Metabolic adaptations of micrometastases alter EV production to generate invasive microenvironments
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    Catalytically distinct metabolic enzyme isocitrate dehydrogenase 1 mutants tune phenotype severity in tumor models
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    P4HA1 Mediates Hypoxia-Induced Invasion in Human Pancreatic Cancer Organoids
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    Efflux of N1-acetylspermidine from hepatoma fosters macrophage-mediated immune suppression to dampen immunotherapeutic efficacy
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  42. May 2025
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    Recurrent breakpoints in the BRD4 locus reduce toxicity associated with gene amplification
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  47. Apr 2025
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    Tribbles Pseudokinase 3 Converts Sorafenib Therapy to Neutrophil‐Mediated Lung Metastasis in Hepatocellular Carcinoma
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    An Aurora kinase A-BOD1L1-PP2A B56 axis promotes chromosome segregation fidelity
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  50. Mar 2025
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    Transcriptional repressor Capicua is a gatekeeper of cell-intrinsic interferon responses
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    Suppression of the LKB1-AMPK-SLC7A11-GSH signaling pathway sensitizes NSCLC to albumin-bound paclitaxel via oxidative stress
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    PLEKHA4 knockdown induces apoptosis in melanoma cells through the MAPK and β‑catenin signaling pathways
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    A compendium of Amplification-Related Gain Of Sensitivity genes in human cancer
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  56. Jan 2025
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    Identification of a distal enhancer of Ucp1 essential for thermogenesis and mitochondrial function in brown fat
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  58. Dec 2024
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    MYO1F positions cGAS on the plasma membrane to ensure full and functional signaling
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  63. Nov 2024
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  66. Sep 2024
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  70. Aug 2024
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    Potential Role of APOBEC3 Family Proteins in SARS-CoV-2 Replication
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  77. Jul 2024
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    ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer
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    BACH1 inhibits senescence, obesity, and short lifespan by ferroptotic FGF21 secretion
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  80. Jun 2024
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    Toll-like receptor 4 signaling activation domains promote CAR T cell function against solid tumors
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  82. May 2024
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    Pharmacologic Targeting of Histone H3K27 Acetylation/BRD4-dependent Induction of ALDH1A3 for Early-phase Drug Tolerance of Gastric Cancer
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    Long-term Multimodal Recording Reveals Epigenetic Adaptation Routes in Dormant Breast Cancer Cells
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    Targeting Dendritic Cell Dysfunction to Circumvent Anti-PD1 Resistance in Head and Neck Cancer
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  87. Apr 2024
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    GPATCH8 modulates mutant SF3B1 mis-splicing and pathogenicity in hematologic malignancies
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    Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome
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  90. Mar 2024
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    Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
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    scAbsolute: measuring single-cell ploidy and replication status
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  93. Feb 2024
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    A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis
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    Prolonged overexpression of PLK4 leads to formation of centriole rosette clusters that are connected via canonical centrosome linker proteins
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    Magnetic Resonance Imaging of Iron Metabolism with T2* Mapping Predicts an Enhanced Clinical Response to Pharmacologic Ascorbate in Patients with GBM
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    Stromal-derived MAOB promotes prostate cancer growth and progression
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    Gamma protocadherins in vascular endothelial cells inhibit Klf2/4 to promote atherosclerosis
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  99. Dec 2023
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  101. Nov 2023
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    ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers
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  103. Oct 2023
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    B cell directed CAR-T cell therapy results in activation of CD8+ cytotoxic CAR-negative bystander T cells in both non-human primates and patients
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  105. Jun 2023
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    Zika Virus Induces Degradation of the Numb Protein Required through Embryonic Neurogenesis
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    Zika Virus Induces the Degradation of the Numb Protein that is Required through Embryonic Neurogenesis
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  108. May 2023
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    Mechanisms controlling membrane recruitment and activation of autoinhibited SHIP1
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  110. Mar 2023
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    DAXX adds a de novo H3.3K9me3 deposition pathway to the histone chaperone network
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  112. Feb 2023
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    Preclinical evaluation of a COVID-19 vaccine candidate based on a recombinant RBD fusion heterodimer of SARS-CoV-2
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  114. Jan 2023
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    Natural Coevolution of Tumor and Immunoenvironment in Glioblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9716251/
  116. Oct 2022
  117. www.sciencedirect.com www.sciencedirect.com
    Histone methylation antagonism drives tumor immune evasion in squamous cell carcinomas
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    sciencedirect.com/science/article/pii/S1097276522008966
  118. May 2022
  119. www.sciencedirect.com www.sciencedirect.com
    NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition
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    sciencedirect.com/science/article/pii/S1097276522003264
  120. Apr 2022
  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MLL5 is involved in retinal photoreceptor maturation through facilitating CRX-mediated photoreceptor gene transactivation
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    ncbi.nlm.nih.gov/pmc/articles/PMC8961232/
  122. Mar 2022
  123. aacrjournals.org aacrjournals.org
    Conduit CAR: Redirecting CAR T-Cell Specificity with A Universal and Adaptable Bispecific Antibody Platform
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    aacrjournals.org/cancerrescommun/article/2/3/146/682301/Conduit-CAR-Redirecting-CAR-T-Cell-Specificity
  124. Sep 2021
  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activity and mechanism of acquired resistance to tarloxotinib in HER2 mutant lung cancer: an in vitro study
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    ncbi.nlm.nih.gov/pmc/articles/PMC8435395/
  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel potent anti-STEAP1 bispecific antibody to redirect T cells for cancer immunotherapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC8438958/