74 Matching Annotations
  1. Oct 2025
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    Arsenic regulates ALKBH1 abundance and substrate specificity to promote translation and tumorigenicity
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    sciencedirect.com/science/article/pii/S2211124725010824
  3. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004225019388-main-html.html
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    54.241.53.176/aabc17a3284ddf7c4ef1d41478982b98da9df7d0/1-s2.0-S2589004225019388-main-html.html
  4. Sep 2025
  5. www.biorxiv.org www.biorxiv.org
    SH2-mediated steric occlusion of the C2 domain regulates autoinhibition of SHIP1 inositol 5-phosphatase
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    biorxiv.org/content/10.1101/2025.09.02.673847v1
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12376514/
  7. Aug 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An EGFR Co-Amplified and De Novo Long Noncoding RNA HELDR Promotes Glioblastoma Malignancy through KAT7-Driven Gene Programs
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    pmc.ncbi.nlm.nih.gov/articles/PMC12270211/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Four Amino Acid Intracellular Motif of VISTA Blocks Growth Receptor Signaling in Cancer Cells to Induce Tumor Suppression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12317733/
  10. Jul 2025
  11. link.springer.com link.springer.com
    Nectin-4 expression in upper and lower tract urothelial carcinoma: correlation with early-stage disease and prognostic relevance
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    link.springer.com/article/10.1007/s00428-025-04164-9
  12. Jun 2025
  13. www.sciencedirect.com www.sciencedirect.com
    An integrated proteomic portrait of prostate cancer progression
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    sciencedirect.com/science/article/pii/S2211124725005996
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HSF1 remodels mitochondrial biogenesis and function in cancer cells via TIMM17A
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    pmc.ncbi.nlm.nih.gov/articles/PMC12132197/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Metabolic adaptations of micrometastases alter EV production to generate invasive microenvironments
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    pmc.ncbi.nlm.nih.gov/articles/PMC12147664/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Catalytically distinct metabolic enzyme isocitrate dehydrogenase 1 mutants tune phenotype severity in tumor models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12147185/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    P4HA1 Mediates Hypoxia-Induced Invasion in Human Pancreatic Cancer Organoids
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    pmc.ncbi.nlm.nih.gov/articles/PMC12123483/
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    Efflux of N1-acetylspermidine from hepatoma fosters macrophage-mediated immune suppression to dampen immunotherapeutic efficacy
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    sciencedirect.com/science/article/pii/S1074761325002274
  19. May 2025
  20. 52.53.155.43 52.53.155.43
    PDF-html.html
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  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Perturb-tracing enables high-content screening of multi-scale 3D genome regulators
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    pmc.ncbi.nlm.nih.gov/articles/PMC12074983/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genetic modulation of rare earth nanoparticle biotransformation shapes biological outcomes
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    pmc.ncbi.nlm.nih.gov/articles/PMC11985947/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Recurrent breakpoints in the BRD4 locus reduce toxicity associated with gene amplification
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    pmc.ncbi.nlm.nih.gov/articles/PMC12008804/
  24. Apr 2025
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tribbles Pseudokinase 3 Converts Sorafenib Therapy to Neutrophil‐Mediated Lung Metastasis in Hepatocellular Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11967757/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An Aurora kinase A-BOD1L1-PP2A B56 axis promotes chromosome segregation fidelity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11962599/
  27. Mar 2025
  28. www.sciencedirect.com www.sciencedirect.com
    Transcriptional repressor Capicua is a gatekeeper of cell-intrinsic interferon responses
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    sciencedirect.com/science/article/pii/S1931312825000654
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Suppression of the LKB1-AMPK-SLC7A11-GSH signaling pathway sensitizes NSCLC to albumin-bound paclitaxel via oxidative stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC11915006/
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PLEKHA4 knockdown induces apoptosis in melanoma cells through the MAPK and β‑catenin signaling pathways
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    pmc.ncbi.nlm.nih.gov/articles/PMC11865880/
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of triglyceride metabolism‐associated enhancers alters lipid deposition during adipocyte differentiation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11774232/
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A compendium of Amplification-Related Gain Of Sensitivity genes in human cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11772776/
  33. Jan 2025
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of a distal enhancer of Ucp1 essential for thermogenesis and mitochondrial function in brown fat
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    pmc.ncbi.nlm.nih.gov/articles/PMC11718246/
  35. Dec 2024
  36. www.sciencedirect.com www.sciencedirect.com
    MYO1F positions cGAS on the plasma membrane to ensure full and functional signaling
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    sciencedirect.com/science/article/pii/S1097276524009511
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DNA Methylation in the CYP3A Distal Regulatory Region (DRR) Is Associated with the Expression of CYP3A5 and CYP3A7 in Human Liver Samples
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    pmc.ncbi.nlm.nih.gov/articles/PMC11596782/
  38. www.biorxiv.org www.biorxiv.org
    Polycomb Repressive Complex 2 promotes atherosclerotic plaque vulnerability
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    biorxiv.org/content/10.1101/2024.12.02.626505v1
  39. www.sciencedirect.com www.sciencedirect.com
    A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control
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    sciencedirect.com/science/article/pii/S1074761324004904
  40. Nov 2024
  41. www.sciencedirect.com www.sciencedirect.com
    Pericancerous cross-presentation to cytotoxic T lymphocytes impairs immunotherapeutic efficacy in hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S1535610824004008
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chromatin protein complexes involved in gene repression in lamina-associated domains
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    pmc.ncbi.nlm.nih.gov/articles/PMC11535540/
  43. Sep 2024
  44. www.sciencedirect.com www.sciencedirect.com
    FABP4-mediated lipid metabolism promotes TNBC progression and breast cancer stem cell activity
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    sciencedirect.com/science/article/pii/S0304383524006669
  45. www.sciencedirect.com www.sciencedirect.com
    Identification of Cables1 as a critical host factor that promotes ALV-J replication via genome-wide CRISPR/Cas9 gene knockout screening
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    sciencedirect.com/science/article/pii/S0021925824023056
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endothelial γ-protocadherins inhibit KLF2 and KLF4 to promote atherosclerosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11399086/
  47. Aug 2024
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oxysterol binding protein (OSBP) contributes to hepatitis E virus replication
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    ncbi.nlm.nih.gov/pmc/articles/PMC11265327/
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fructose vs. glucose: modulating stem cell growth and function through sugar supplementation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11301265/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Potential Role of APOBEC3 Family Proteins in SARS-CoV-2 Replication
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    ncbi.nlm.nih.gov/pmc/articles/PMC11281575/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypermetabolic state is associated with circadian rhythm disruption in mouse and human cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11287162/
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD38 restrains the activity of extracellular cGAMP in a model of multiple myeloma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11091702/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ERK Activation by BRAFV600E suppresses mesenchymal migration and tumorigenesis by inhibiting RAC1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11042182/
  54. Jul 2024
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11285331/
  56. www.sciencedirect.com www.sciencedirect.com
    BACH1 inhibits senescence, obesity, and short lifespan by ferroptotic FGF21 secretion
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    sciencedirect.com/science/article/pii/S2211124724007319
  57. Jun 2024
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Toll-like receptor 4 signaling activation domains promote CAR T cell function against solid tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11152746/
  59. May 2024
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacologic Targeting of Histone H3K27 Acetylation/BRD4-dependent Induction of ALDH1A3 for Early-phase Drug Tolerance of Gastric Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11104289/
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Catalytically distinct IDH1 mutants tune phenotype severity in tumor models
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    ncbi.nlm.nih.gov/pmc/articles/PMC11071412/
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long-term Multimodal Recording Reveals Epigenetic Adaptation Routes in Dormant Breast Cancer Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11061610/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting Dendritic Cell Dysfunction to Circumvent Anti-PD1 Resistance in Head and Neck Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11061605/
  64. Apr 2024
  65. www.sciencedirect.com www.sciencedirect.com
    GPATCH8 modulates mutant SF3B1 mis-splicing and pathogenicity in hematologic malignancies
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    sciencedirect.com/science/article/pii/S1097276524002843
  66. www.sciencedirect.com www.sciencedirect.com
    Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome
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    sciencedirect.com/science/article/pii/S221112472400439X
  67. Mar 2024
  68. www.sciencedirect.com www.sciencedirect.com
    Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
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    sciencedirect.com/science/article/pii/S1097276524001758
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    scAbsolute: measuring single-cell ploidy and replication status
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    ncbi.nlm.nih.gov/pmc/articles/PMC10910719/
  70. Feb 2024
  71. www.sciencedirect.com www.sciencedirect.com
    A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis
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    sciencedirect.com/science/article/pii/S1097276524000984
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prolonged overexpression of PLK4 leads to formation of centriole rosette clusters that are connected via canonical centrosome linker proteins
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    ncbi.nlm.nih.gov/pmc/articles/PMC10883960/
  73. aacrjournals.org aacrjournals.org
    Magnetic Resonance Imaging of Iron Metabolism with T2* Mapping Predicts an Enhanced Clinical Response to Pharmacologic Ascorbate in Patients with GBM
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    aacrjournals.org/clincancerres/article/30/2/283/733204/Magnetic-Resonance-Imaging-of-Iron-Metabolism-with
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stromal-derived MAOB promotes prostate cancer growth and progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10857382/
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gamma protocadherins in vascular endothelial cells inhibit Klf2/4 to promote atherosclerosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10827163/
  76. Dec 2023
  77. 52.53.155.43 52.53.155.43
    ccr-22-3952-html.html
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  78. Nov 2023
  79. www.biorxiv.org www.biorxiv.org
    ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers
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    biorxiv.org/content/10.1101/2023.10.24.563645v1
  80. Oct 2023
  81. www.biorxiv.org www.biorxiv.org
    B cell directed CAR-T cell therapy results in activation of CD8+ cytotoxic CAR-negative bystander T cells in both non-human primates and patients
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    biorxiv.org/content/10.1101/2023.09.28.559936v1
  82. Jun 2023
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Zika Virus Induces Degradation of the Numb Protein Required through Embryonic Neurogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10301363/
  84. 52.53.155.43 52.53.155.43
    Zika Virus Induces the Degradation of the Numb Protein that is Required through Embryonic Neurogenesis
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    52.53.155.43/af98b336aea3b497d23623e19829a8fe1de933b5/preprints202304.0435.v1-html.html
  85. May 2023
  86. www.biorxiv.org www.biorxiv.org
    Mechanisms controlling membrane recruitment and activation of autoinhibited SHIP1
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    biorxiv.org/content/10.1101/2023.04.30.538895v1
  87. Mar 2023
  88. www.sciencedirect.com www.sciencedirect.com
    DAXX adds a de novo H3.3K9me3 deposition pathway to the histone chaperone network
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    sciencedirect.com/science/article/pii/S1097276523001077
  89. Feb 2023
  90. www.sciencedirect.com www.sciencedirect.com
    Preclinical evaluation of a COVID-19 vaccine candidate based on a recombinant RBD fusion heterodimer of SARS-CoV-2
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    sciencedirect.com/science/article/pii/S2589004223002031
  91. Jan 2023
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Natural Coevolution of Tumor and Immunoenvironment in Glioblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9716251/
  93. Oct 2022
  94. www.sciencedirect.com www.sciencedirect.com
    Histone methylation antagonism drives tumor immune evasion in squamous cell carcinomas
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    sciencedirect.com/science/article/pii/S1097276522008966
  95. May 2022
  96. www.sciencedirect.com www.sciencedirect.com
    NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition
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    sciencedirect.com/science/article/pii/S1097276522003264
  97. Apr 2022
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MLL5 is involved in retinal photoreceptor maturation through facilitating CRX-mediated photoreceptor gene transactivation
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    ncbi.nlm.nih.gov/pmc/articles/PMC8961232/
  99. Mar 2022
  100. aacrjournals.org aacrjournals.org
    Conduit CAR: Redirecting CAR T-Cell Specificity with A Universal and Adaptable Bispecific Antibody Platform
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    aacrjournals.org/cancerrescommun/article/2/3/146/682301/Conduit-CAR-Redirecting-CAR-T-Cell-Specificity
  101. Sep 2021
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activity and mechanism of acquired resistance to tarloxotinib in HER2 mutant lung cancer: an in vitro study
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    ncbi.nlm.nih.gov/pmc/articles/PMC8435395/
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel potent anti-STEAP1 bispecific antibody to redirect T cells for cancer immunotherapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC8438958/