58 Matching Annotations
  1. Feb 2025
  2. www.sciencedirect.com www.sciencedirect.com
    A methyltransferase-independent role for METTL1 in tRNA aminoacylation and oncogenic transformation
    1
    1. scibot 04 Feb 2025
      plasmid_14888

      DOI: 10.1016/j.molcel.2025.01.003

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    sciencedirect.com/science/article/pii/S1097276525000036
  3. Jan 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CDKN2A/B homozygous deletion sensitizes IDH-mutant glioma to CDK4/6 inhibition
    1
    1. scibot 25 Jan 2025
      RRID:Addgene_14888

      DOI: 10.1158/1078-0432.CCR-24-0562

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    pmc.ncbi.nlm.nih.gov/articles/PMC11250907/
  5. www.sciencedirect.com www.sciencedirect.com
    Enhanced kinase translocation reporters for simultaneous real-time measurement of PKA, ERK, and calcium
    1
    1. scibot 16 Jan 2025
      Addgene_14888

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    sciencedirect.com/science/article/pii/S0021925825000304
  6. 52.53.155.43 52.53.155.43
    PDF-html.html
    1
    1. scibot 05 Jan 2025
      RRID:Addgene_14888

      DOI: 10.1242/jcs.263459

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    52.53.155.43/536d4d4f3cdb6d7a39ee26c6732b96f318bba10f/PDF-html.html
  7. Dec 2024
  8. www.sciencedirect.com www.sciencedirect.com
    Castrate-resistant prostate cancer response to taxane is determined by an HNF1-dependent apoptosis resistance circuit
    1
    1. scibot 24 Dec 2024
      plasmid # 14888

      DOI: 10.1016/j.xcrm.2024.101868

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    sciencedirect.com/science/article/pii/S2666379124006396
  9. Nov 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Profound synthetic lethality between SMARCAL1 and FANCM
    1
    1. scibot 17 Nov 2024
      Addgene Cat# 14888

      DOI: 10.1016/j.molcel.2024.10.016

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    sciencedirect.com/science/article/pii/S1097276524008566
  11. www.sciencedirect.com www.sciencedirect.com
    Degradome analysis to identify direct protein substrates of small-molecule degraders
    2
    1. scibot 14 Nov 2024
      AddgeneCat# 14888

      DOI: 10.1016/j.chembiol.2024.10.007

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    2. scibot 14 Nov 2024
      Addgene_14888

      DOI: 10.1016/j.chembiol.2024.10.007

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    sciencedirect.com/science/article/pii/S2451945624004422
  12. Sep 2024
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of the PERK/eIF2α axis is a pivotal prerequisite of taxanes to cancer cell apoptosis and renders synergism to overcome paclitaxel resistance in breast cancer cells
    1
    1. scibot 29 Sep 2024
      14888

      DOI: 10.1186/s12935-024-03443-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC11256575/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PDCD10 Is a Key Player in TMZ-Resistance and Tumor Cell Regrowth: Insights into Its Underlying Mechanism in Glioblastoma Cells
    1
    1. scibot 26 Sep 2024
      plasmid_14888

      DOI: 10.3390/cells13171442

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    ncbi.nlm.nih.gov/pmc/articles/PMC11394141/
  15. Aug 2024
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PUS7‐dependent pseudouridylation of ALKBH3 mRNA inhibits gastric cancer progression
    1
    1. scibot 26 Aug 2024
      VSV‐G

      DOI: 10.1002/ctm2.1811

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    ncbi.nlm.nih.gov/pmc/articles/PMC11341916/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Time-of-day effects of cancer drugs revealed by high-throughput deep phenotyping
    1
    1. scibot 26 Aug 2024
      Addgene_14888

      DOI: 10.1038/s41467-024-51611-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC11339390/
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Library‐Assisted Evolution in Eukaryotic Cells Yield Adenine Base Editors with Enhanced Editing Specificity
    1
    1. scibot 17 Aug 2024
      14888

      DOI: 10.1002/advs.202309004

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    ncbi.nlm.nih.gov/pmc/articles/PMC11321652/
  19. Jun 2024
  20. www.cell.com www.cell.com
    An HIV-1 CRISPR-Cas9 membrane trafficking screen reveals a role for PICALM intersecting endolysosomes and immunity
    1
    1. scibot 30 Jun 2024
      Addgene_14888

      DOI: 10.1016/j.isci.2024.110131

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    cell.com/iscience/abstract/S2589-0042(24)01356-7
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evaluation of the role of AXL in fusion-positive pediatric rhabdomyosarcoma identifies the small-molecule inhibitor bemcentinib (BGB324) as potent chemosensitizer
    1
    1. scibot 10 Jun 2024
      RRID:Addgene_14888

      DOI: 10.1158/1535-7163.MCT-23-0285

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    ncbi.nlm.nih.gov/pmc/articles/PMC11148551/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A synthetic lethal dependency on casein kinase 2 in response to replication-perturbing therapeutics in RB1-deficient cancer cells
    1
    1. scibot 07 Jun 2024
      14888

      DOI: 10.1126/sciadv.adj1564

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    ncbi.nlm.nih.gov/pmc/articles/PMC11114247/
  23. May 2024
  24. 52.53.155.43 52.53.155.43
    mct-23-0285-html.html
    1
    1. scibot 23 May 2024
      RRID:Addgene_14888

      DOI: 10.1158/1535-7163.mct-23-0285

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    52.53.155.43/c4dad1b9844bc76f61b814848871e558944174e3/mct-23-0285-html.html
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NFATC2IP is a mediator of SUMO-dependent genome integrity
    1
    1. scibot 05 May 2024
      14888

      DOI: 10.1101/gad.350914.123

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    ncbi.nlm.nih.gov/pmc/articles/PMC11065178/
  26. www.sciencedirect.com www.sciencedirect.com
    Activity-driven synaptic translocation of LGI1 controls excitatory neurotransmission
    1
    1. scibot 03 May 2024
      Plasmid_14888

      DOI: 10.1016/j.celrep.2024.114186

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    sciencedirect.com/science/article/pii/S221112472400514X
  27. Apr 2024
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined SNPs sequencing and allele specific proteomics capture reveal functional causality underpinning the 2p25 prostate cancer susceptibility locus
    1
    1. scibot 30 Apr 2024
      14888

      DOI: 10.21203/rs.3.rs-3943095/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11030545/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular density-accelerated binding-site maturation underlies CENP-T-dependent kinetochore assembly
    1
    1. scibot 15 Apr 2024
      VSV-G

      DOI: 10.1101/2024.02.25.581584

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    ncbi.nlm.nih.gov/pmc/articles/PMC10925139/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reprograming skin fibroblasts into Sertoli cells: a patient-specific tool to understand effects of genetic variants on gonadal development
    1
    1. scibot 15 Apr 2024
      VSV-G

      DOI: 10.1186/s13293-024-00599-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC10958866/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ether lipids influence cancer cell fate by modulating iron uptake
    1
    1. scibot 14 Apr 2024
      VSVG

      DOI: 10.1101/2024.03.20.585922

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    ncbi.nlm.nih.gov/pmc/articles/PMC10983928/
  32. www.sciencedirect.com www.sciencedirect.com
    Mutant FOXO1 controls an oncogenic network via enhancer accessibility
    1
    1. scibot 11 Apr 2024
      AddgeneCAT#14888

      DOI: 10.1016/j.xgen.2024.100537

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    sciencedirect.com/science/article/pii/S2666979X24000934
  33. Mar 2024
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct ontogenetic lineages dictate cDC2 heterogeneity
    1
    1. scibot 08 Mar 2024
      VSV G

      DOI: 10.1038/s41590-024-01745-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC10907303/
  35. Feb 2024
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transactivation of Met signaling by oncogenic Gnaq drives the evolution of melanoma in Hgf-Cdk4 mice
    1
    1. scibot 22 Feb 2024
      plasmid_14888

      DOI: 10.1038/s41417-024-00744-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC11192630/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of LATS kinases reduces tumorigenicity and increases the sensitivity of human chronic myelogenous leukemia cells to imatinib
    1
    1. scibot 21 Feb 2024
      VSV-G

      DOI: 10.1038/s41598-024-54728-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC10874434/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The acidic intrinsically disordered region of the inflammatory mediator HMGB1 mediates fuzzy interactions with CXCL12
    1
    1. scibot 15 Feb 2024
      14888

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    ncbi.nlm.nih.gov/pmc/articles/PMC10853541/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exploiting epigenetic targets to overcome taxane resistance in prostate cancer
    1
    1. scibot 15 Feb 2024
      14888

      DOI: 10.1038/s41419-024-06422-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10861560/
  40. www.sciencedirect.com www.sciencedirect.com
    Retrospective identification of cell-intrinsic factors that mark pluripotency potential in rare somatic cells
    1
    1. scibot 09 Feb 2024
      Addgene Plasmid #14888

      DOI: 10.1016/j.cels.2024.01.001

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    sciencedirect.com/science/article/pii/S240547122400022X
  41. www.nature.com www.nature.com
    A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1
    1
    1. scibot 08 Feb 2024
      RRID:Addgene_14888

      DOI: 10.1038/s41467-024-45067-8

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    nature.com/articles/s41467-024-45067-8
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytoplasmic accumulation and plasma membrane association of anillin and Ect2 promote confined migration and invasion
    1
    1. scibot 05 Feb 2024
      plasmid_14888

      DOI: 10.21203/rs.3.rs-3640969/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10802709/
  43. Jan 2024
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clonal heterogeneity in ER+ breast cancer reveals the proteasome and PKC as potential therapeutic targets
    1
    1. scibot 12 Jan 2024
      Addgene_14888

      DOI: 10.1038/s41523-023-00604-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC10693625/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epstein-Barr virus miR-BARTs 7 and 9 modulate viral cycle, cell proliferation, and proteomic profiles in Burkitt lymphoma
    1
    1. scibot 11 Jan 2024
      RRID:Addgene_14888

      DOI: 10.1016/j.tvr.2023.200276

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    ncbi.nlm.nih.gov/pmc/articles/PMC11000110/
  46. Aug 2023
  47. www.sciencedirect.com www.sciencedirect.com
    The circadian clock protein Cryptochrome 1 is a direct target and feedback regulator of the Hippo pathway
    1
    1. scibot 05 Aug 2023
      Addgene_14888

      DOI: 10.1016/j.isci.2023.107449

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    sciencedirect.com/science/article/pii/S2589004223015262
  48. May 2023
  49. www.biorxiv.org www.biorxiv.org
    Epstein-Barr virus miR-BARTs 7 and 9 modulate viral cycle, cell proliferation and proteomic profiles in Burkitt lymphoma
    1
    1. scibot 25 May 2023
      RRID:Addgene_14888

      DOI: 10.1101/2023.05.19.538556

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    biorxiv.org/content/10.1101/2023.05.19.538556v1
  50. Apr 2023
  51. elifesciences.org elifesciences.org
    NFATc1 marks articular cartilage progenitors and negatively determines articular chondrocyte differentiation
    1
    1. scibot 12 Apr 2023
      RRID:Addgene_14888

      DOI: 10.7554/eLife.81569

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    elifesciences.org/articles/81569
  52. Nov 2022
  53. www.sciencedirect.com www.sciencedirect.com
    POLθ processes ssDNA gaps and promotes replication fork progression in BRCA1-deficient cells
    1
    1. scibot 18 Nov 2022
      Plasmid_14888

      DOI: 10.1016/j.celrep.2022.111716

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    sciencedirect.com/science/article/pii/S2211124722015947
  54. Oct 2022
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fast generation of forebrain oligodendrocyte spheroids from human embryonic stem cells by transcription factors
    1
    1. scibot 12 Oct 2022
      Plasmid_14888

      DOI: 10.1016/j.isci.2022.105172

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    ncbi.nlm.nih.gov/pmc/articles/PMC9547302/
  56. Sep 2022
  57. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of insulin-like growth factor-1 receptor enhances eribulin-induced DNA damage in colorectal cancer
    1
    1. scibot 15 Sep 2022
      RRID:Addgene_14

      DOI: 10.1111/cas.15558

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    onlinelibrary.wiley.com/doi/10.1111/cas.15558
  58. Aug 2022
  59. www.sciencedirect.com www.sciencedirect.com
    De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma
    1
    1. scibot 22 Aug 2022
      Addgene, Cat# 14888

      DOI: 10.1016/j.ccell.2022.07.011

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    sciencedirect.com/science/article/pii/S1535610822003245
  60. Jun 2022
  61. www.sciencedirect.com www.sciencedirect.com
    Supramolecular assembly of GSK3α as a cellular response to amino acid starvation
    1
    1. scibot 22 Jun 2022
      plasmid_14888

      DOI: 10.1016/j.molcel.2022.05.025

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    sciencedirect.com/science/article/pii/S1097276522004920
  62. link.springer.com link.springer.com
    Potential therapeutic targets discovery by transcriptome analysis of an in vitro human gastric signet ring carcinoma model
    1
    1. scibot 07 Jun 2022
      RRID:Addgene_14888

      DOI: 10.1007/s10120-022-01307-8

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    link.springer.com/article/10.1007/s10120-022-01307-8
  63. Mar 2022
  64. www.nature.com www.nature.com
    In vivo anti-tumor effect of PARP inhibition in IDH1/2 mutant MDS/AML resistant to targeted inhibitors of mutant IDH1/2
    1
    1. scibot 17 Mar 2022
      plasmid_14888

      DOI: 10.1038/s41375-022-01536-x

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    nature.com/articles/s41375-022-01536-x
  65. www.sciencedirect.com www.sciencedirect.com
    Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers
    1
    1. scibot 09 Mar 2022
      Addgene_14888

      DOI: 10.1016/j.immuni.2022.02.004

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    sciencedirect.com/science/article/pii/S107476132200084X
  66. Jan 2022
  67. www.sciencedirect.com www.sciencedirect.com
    TGF-β-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures
    2
    1. scibot 12 Jan 2022
      Cat# 14888

      DOI: 10.1016/j.immuni.2021.12.007

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      Curator: @sophiastull

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    2. scibot 12 Jan 2022
      Addgene_14888

      DOI: 10.1016/j.immuni.2021.12.007

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    sciencedirect.com/science/article/pii/S1074761321005434
  68. Oct 2021
  69. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Tumor cell intrinsic TLR4 signaling promotes melanoma progression and metastatic dissemination
    1
    1. scibot 15 Oct 2021
      plasmid_14888

      DOI: 10.1002/ijc.33804

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    onlinelibrary.wiley.com/doi/10.1002/ijc.33804
  70. Aug 2021
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 06 Aug 2021
      Plasmid_14888

      DOI: 10.1016/j.cmet.2018.07.005

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    ncbi.nlm.nih.gov/pmc/articles/PMC6224545/
  72. Jul 2021
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effective Inhibition of SARS-CoV-2 Entry by Heparin and Enoxaparin Derivatives
    1
    1. scibot 14 Jul 2021
      RRID:Addgene_14888

      DOI: 10.1128/JVI.01987-20

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    ncbi.nlm.nih.gov/pmc/articles/PMC7925120/
  74. May 2021
  75. www.sciencedirect.com www.sciencedirect.com
    The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
    1
    1. scibot 18 May 2021
      Addgene Cat#14888

      DOI: 10.1016/j.cell.2021.04.022

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      RRID:Addgene_14888 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S009286742100502X
  76. Feb 2021
  77. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The aryl hydrocarbon receptor promotes inflammation‐induced dedifferentiation and systemic metastatic spread of melanoma cells
    1
    1. scibot 26 Feb 2021
      plasmid_14888

      DOI: 10.1002/ijc.33252

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    onlinelibrary.wiley.com/doi/10.1002/ijc.33252
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heparan sulfates from bat and human lung and their binding to the spike protein of SARS-CoV-2 virus
    1
    1. scibot 24 Feb 2021
      RRID:Addgene_14888

      DOI: 10.1016/j.carbpol.2021.117797

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC7882221/
  79. Nov 2020
  80. www.nature.com www.nature.com
    Effective screening of SARS-CoV-2 neutralizing antibodies in patient serum using lentivirus particles pseudotyped with SARS-CoV-2 spike glycoprotein
    1
    1. scibot 12 Nov 2020
      RRID:Addgene_14888

      DOI: 10.1038/s41598-020-76135-w

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    nature.com/articles/s41598-020-76135-w
  81. Sep 2020
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531
    1
    1. scibot 26 Sep 2020
      RRID:Addgene_14888

      DOI: 10.7554/eLife.56913

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    ncbi.nlm.nih.gov/pmc/articles/PMC7363447/
  83. www.sciencedirect.com www.sciencedirect.com
    Complexin Suppresses Spontaneous Exocytosis by Capturing the Membrane-Proximal Regions of VAMP2 and SNAP25
    1
    1. scibot 23 Sep 2020
      RRID:Addgene_14888

      DOI: 10.1016/j.celrep.2020.107926

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    sciencedirect.com/science/article/pii/S2211124720309074
  84. doi.org doi.org
    https://doi.org/10.1101/2020.06.08.140236
    1
    1. scibot 16 Sep 2020
      RRID:Addgene_14888

      DOI: 10.1101/2020.06.08.140236

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    doi.org/10.1101/2020.06.08.140236
  85. Jan 2020
  86. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 12 Jan 2020
      plasmid_14888

      DOI: 10.1016/j.stem.2018.12.002

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      Curator: @ethanbadger

      SciCrunch record: plasmid_14888

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      RRID:Addgene_14888 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1934590918305927