85 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NAB2-STAT6 drives an EGR1-dependent neuroendocrine program in solitary fibrous tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12393881/
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    ENPP1 inhibitor with ultralong drug-target residence time as an innate immune checkpoint blockade cancer therapy
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    sciencedirect.com/science/article/pii/S2666379125004094
  4. Aug 2025
  5. link.springer.com link.springer.com
    Connexin 43 inhibitors reduce cell viability in glioblastoma and astrocyte co-culture systems
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    link.springer.com/article/10.1007/s11033-025-10902-8
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    Functional Differences Between SIRPα Splice Isoforms
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    pmc.ncbi.nlm.nih.gov/articles/PMC12324903/
  7. Jul 2025
  8. www.science.org www.science.org
    CD8+ T cell–derived CD40L mediates noncanonical cytotoxicity in CD40-expressing cancer cells
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    science.org/doi/10.1126/sciadv.adr9331
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of Eml1 alters microtubule-associated protein networks in mouse brain heterotopia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12229495/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CCNY-mediated phosphorylation and TET2-BACH1-driven DNA demethylation activate PRC1 to augment NSCLC progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12261648/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PHGDH Induction by MAPK is Essential for Melanoma Formation and Creates an Actionable Metabolic Vulnerability
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    pmc.ncbi.nlm.nih.gov/articles/PMC11735329/
  12. Jun 2025
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    Nerve-to-cancer transfer of mitochondria during cancer metastasis
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    nature.com/articles/s41586-025-09176-8
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    De novo assembly of RNA m6A modification factors into viral genome-associated nuclear bodies drives HCMV RNA accumulation
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    sciencedirect.com/science/article/pii/S2211124725005972
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    Low-dose photodynamic therapy promotes vascular E-selectin expression in chest malignancies, improving immune infiltration and tumor control
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    pmc.ncbi.nlm.nih.gov/articles/PMC12161339/
  16. May 2025
  17. www.science.org www.science.org
    CD8+ T cell–derived CD40L mediates noncanonical cytotoxicity in CD40-expressing cancer cells
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    science.org/doi/10.1126/sciadv.adr9331
  18. 52.53.155.43 52.53.155.43
    CapdevilaCastillo_columbia_0054D_18600-html.html
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    Establishment of bovine extraembryonic endoderm stem cells enables efficient blastoid formation
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    sciencedirect.com/science/article/pii/S2211124725004784
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    m6A-Modified GATA2 Enhances Odontogenic Differentiation in Stem Cells from the Apical Papilla
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    pmc.ncbi.nlm.nih.gov/articles/PMC11988903/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hyperactivation of RAB5 disrupts the endosomal Rab cascade leading to endolysosomal dysregulation in Down syndrome: A necessary role for increased APP gene dose
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    pmc.ncbi.nlm.nih.gov/articles/PMC12058456/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A dual-fluorescence assay for gene delivery vehicle screening in macrophages with an inflammation-inducible reporter construct
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    pmc.ncbi.nlm.nih.gov/articles/PMC12062070/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Hydrogel-Based Multiplex Coculture Platform for Retinal Component Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12015949/
  24. Apr 2025
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LGALS3BP antibody-drug conjugate enhances tumor-infiltrating lymphocytes and synergizes with immunotherapy to restrain neuroblastoma growth
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    pmc.ncbi.nlm.nih.gov/articles/PMC11992825/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Promyelocytic Leukemia Protein (PML) Regulates Stem Cell Pluripotency Through Novel Sumoylation Targets
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    pmc.ncbi.nlm.nih.gov/articles/PMC11818296/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In vitro and in vivo neutralization of Dengue virus by a single domain antibody
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    pmc.ncbi.nlm.nih.gov/articles/PMC11968175/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SET8 inhibition preserves PTEN to attenuate kidney cell apoptosis in cisplatin nephrotoxicity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11958763/
  29. Mar 2025
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Glioblastoma progression is hindered by melatonin-primed mesenchymal stromal cells through dynamic intracellular and extracellular reorganizations
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    pmc.ncbi.nlm.nih.gov/articles/PMC11898303/
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Haplotype rather than single causal variants effects contribute to regulatory gene expression associations in human myeloid cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11838257/
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nematode serine protease inhibitor SPI-I8 negatively regulates host NF-κB signalling by hijacking MKRN1-mediated polyubiquitination of RACK1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11876351/
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Characterization of spike S1/S2 processing and entry pathways of lentiviral pseudoviruses bearing seasonal human coronaviruses NL63, 229E, and HKU1 spikes
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    pmc.ncbi.nlm.nih.gov/articles/PMC11878054/
  34. Feb 2025
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PRDM16 controls smooth muscle cell fate in atherosclerosis
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  36. 52.53.155.43 52.53.155.43
    bph17305-sup-0001-sars cov 2 rucaparib supplementary 2-html.html
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  37. Jan 2025
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transcriptional regulation of adipocyte lipolysis by IRF2BP2
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    pmc.ncbi.nlm.nih.gov/articles/PMC11698119/
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Human TRMT1 and TRMT1L paralogs ensure the proper modification state, stability, and function of tRNAs
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    pmc.ncbi.nlm.nih.gov/articles/PMC11831618/
  40. Dec 2024
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Development of Liver-Targeting αVβ5+ Exosomes as Anti-TGF-β Nanocarriers for the Treatment of the Pre-Metastatic Niche
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    pmc.ncbi.nlm.nih.gov/articles/PMC11673512/
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fibrosis‐Encapsulated Tumoroid, A Solid Cancer Assembloid Model for Cancer Research and Drug Screening
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    pmc.ncbi.nlm.nih.gov/articles/PMC11650424/
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Adaptor protein 3BP2 regulates gene expression in addition to the ubiquitination and proteolytic activity of MALT1 in dectin-1–stimulated cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11647625/
  44. Oct 2024
  45. www.mdpi.com www.mdpi.com
    Enhancement of Triple-Negative Breast Cancer-Specific Induction of Cell Death by Silver Nanoparticles by Combined Treatment with Proteotoxic Stress Response Inhibitors
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    mdpi.com/2079-4991/14/19/1564
  46. Sep 2024
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SET8 inhibition preserves PTEN to attenuate kidney cell apoptosis in cisplatin nephrotoxicity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11343278/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    New Insights into the Exosome-Induced Migration of Uveal Melanoma Cells and the Pre-Metastatic Niche Formation in the Liver
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    ncbi.nlm.nih.gov/pmc/articles/PMC11394004/
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    The mrp-3 gene is involved in haem efflux and detoxification in a blood-feeding nematode
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    link.springer.com/article/10.1186/s12915-024-02001-0
  50. Aug 2024
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CAR T-cell-mediated delivery of bispecific innate immune cell engagers for neuroblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11336212/
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Allosteric nanobodies to study the interactions between SOS1 and RAS
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    ncbi.nlm.nih.gov/pmc/articles/PMC11266648/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The exocyst subunit EXOC2 regulates the toxicity of expanded GGGGCC repeats in C9ORF72-ALS/FTD
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    ncbi.nlm.nih.gov/pmc/articles/PMC11299523/
  54. www.biorxiv.org www.biorxiv.org
    Transcriptional regulation of adipocyte lipolysis by IRF2BP2
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    biorxiv.org/content/10.1101/2024.07.31.605689v1
  55. Jul 2024
  56. www.sciencedirect.com www.sciencedirect.com
    PELI2 is a negative regulator of STING signaling that is dynamically repressed during viral infection
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    sciencedirect.com/science/article/pii/S1097276524004799
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNASeq highlights ATF6 pathway regulators for CHO cell engineering with different impacts of ATF6β and WFS1 knockdown on fed-batch production of IgG1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11187196/
  58. Jun 2024
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial respiratory function is preserved under cysteine starvation via glutathione catabolism in NSCLC
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    ncbi.nlm.nih.gov/pmc/articles/PMC11102494/
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    Time-resolved fate mapping identifies the intestinal upper crypt zone as an origin of Lgr5+ crypt base columnar cells
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    sciencedirect.com/science/article/pii/S0092867424004914
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DNMT3B splicing dysregulation mediated by SMCHD1 loss contributes to DUX4 overexpression and FSHD pathogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11135424/
  62. May 2024
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DDX18 Facilitates the Tumorigenesis of Lung Adenocarcinoma by Promoting Cell Cycle Progression through the Upregulation of CDK4
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    ncbi.nlm.nih.gov/pmc/articles/PMC11084921/
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NAB2-STAT6 drives an EGR1-dependent neuroendocrine program in Solitary Fibrous Tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11042251/
  65. Apr 2024
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MAPK-mediated PHGDH induction is essential for melanoma formation and represents an actionable vulnerability
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    ncbi.nlm.nih.gov/pmc/articles/PMC11042198/
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Role of Heat-Induced Stress Granules in the Blood–Testis Barrier of Mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC11011666/
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modulation of alveolar macrophage and mitochondrial fitness by medicinal plant-derived nanovesicles to mitigate acute lung injury and viral pneumonia
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    ncbi.nlm.nih.gov/pmc/articles/PMC11025283/
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    Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages
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    sciencedirect.com/science/article/pii/S1074761324001419
  70. Mar 2024
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Silver Nanoparticles Selectively Treat Neurofibromatosis Type 1-Associated Plexiform Neurofibroma Cells at Doses That Do Not Affect Patient-Matched Schwann Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10975375/
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A FACS-based novel isolation technique identifies heterogeneous CTCs in oral squamous cell carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10925612/
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    Protocol for the isolation of tumor cell-derived extracellular vesicles followed by in vivo metastasis assessment in a murine ovarian cancer model
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    sciencedirect.com/science/article/pii/S2666166724001084
  74. Jan 2024
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLC2A9 rs16890979 reduces uric acid absorption by kidney organoids
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    ncbi.nlm.nih.gov/pmc/articles/PMC10806012/
  76. Dec 2023
  77. www.mdpi.com www.mdpi.com
    A Novel Metastatic Estrogen Receptor-Expressing Breast Cancer Model with Antiestrogen Responsiveness
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    mdpi.com/2072-6694/15/24/5773
  78. Nov 2023
  79. www.biorxiv.org www.biorxiv.org
    Dissecting signaling regulators driving AXL-mediated bypass resistance and associated phenotypes by phosphosite perturbations
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    biorxiv.org/content/10.1101/2023.10.20.563266v1
  80. Sep 2023
  81. dx.doi.org dx.doi.org
    Loss of CDKN2A Cooperates with WWTR1(TAZ)–CAMTA1 Gene Fusion to Promote Tumor Progression in Epithelioid Hemangioendothelioma
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    dx.doi.org/10.1158/1078-0432.CCR-22-2497
  82. www.nature.com www.nature.com
    β2-AR inhibition enhances EGFR antibody efficacy hampering the oxidative stress response machinery
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    nature.com/articles/s41419-023-06129-9
  83. Aug 2023
  84. www.sciencedirect.com www.sciencedirect.com
    Dual role of the adhesion G-protein coupled receptor ADRGE5/CD97 in glioblastoma invasion and proliferation
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    sciencedirect.com/science/article/pii/S0021925823021336
  85. May 2023
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Syngeneic mouse model of human HER2+ metastatic breast cancer for the evaluation of trastuzumab emtansine combined with oncolytic rhabdovirus
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    ncbi.nlm.nih.gov/pmc/articles/PMC10154558/
  87. Apr 2023
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gain of chromosome 1q perturbs a competitive endogenous RNA network to promote melanoma metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC9971359/
  89. Jan 2023
  90. www.science.org www.science.org
    Species-specific self-DNA detection mechanisms by mammalian cyclic GMP-AMP synthases
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    science.org/doi/10.1126/sciimmunol.abp9765
  91. Aug 2022
  92. www.sciencedirect.com www.sciencedirect.com
    SMNDC1 links chromatin remodeling and splicing to regulate pancreatic hormone expression
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    sciencedirect.com/science/article/pii/S2211124722011081
  93. Jun 2022
  94. www.sciencedirect.com www.sciencedirect.com
    Robust anti-SARS-CoV2 single domain antibodies cross neutralize multiple viruses
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    sciencedirect.com/science/article/pii/S2589004222008215
  95. Apr 2022
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MLL5 is involved in retinal photoreceptor maturation through facilitating CRX-mediated photoreceptor gene transactivation
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    ncbi.nlm.nih.gov/pmc/articles/PMC8961232/
  97. Mar 2022
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aberrant induction of a mesenchymal/stem-cell program engages senescence in normal mammary epithelial cells.
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    ncbi.nlm.nih.gov/pmc/articles/PMC8867383/
  99. Nov 2021
  100. www.sciencedirect.com www.sciencedirect.com
    Partial resistance of SARS-CoV-2 Delta variants to vaccine-elicited antibodies and convalescent sera
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    sciencedirect.com/science/article/pii/S2589004221013109
  101. Sep 2021
  102. www.sciencedirect.com www.sciencedirect.com
    GAGE mediates radio resistance in cervical cancers via the regulation of chromatin accessibility
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    sciencedirect.com/science/article/pii/S2211124721010597
  103. Aug 2021
  104. www.sciencedirect.com www.sciencedirect.com
    Actinin BioID reveals sarcomere crosstalk with oxidative metabolism through interactions with IGF2BP2
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    sciencedirect.com/science/article/pii/S2211124721009426
  105. Jul 2021
  106. elifesciences.org elifesciences.org
    Structural and functional insights into the bona fide catalytic state of Streptococcus pyogenes Cas9 HNH nuclease domain
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    elifesciences.org/articles/46500
  107. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
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    sciencedirect.com/science/article/pii/S153561081930577X
  108. May 2021
  109. www.sciencedirect.com www.sciencedirect.com
    3D mesenchymal cell migration is driven by anterior cellular contraction that generates an extracellular matrix prestrain
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    sciencedirect.com/science/article/pii/S153458072100157X
  110. Mar 2021
  111. www.sciencedirect.com www.sciencedirect.com
    ER-directed TREX1 limits cGAS activation at micronuclei
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    sciencedirect.com/science/article/pii/S1097276520309588
  112. Feb 2021
  113. www.sciencedirect.com www.sciencedirect.com
    microRNA-induced translational control of antiviral immunity by the cap-binding protein 4EHP
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    sciencedirect.com/science/article/pii/S1097276521000502
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Three-Dimensional Alzheimer’s Disease Cell Culture Model Using iPSC-Derived Neurons Carrying A246E Mutation in PSEN1
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    ncbi.nlm.nih.gov/pmc/articles/PMC7325960/
  115. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
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    sciencedirect.com/science/article/pii/S153561081930577X
  116. Dec 2020
  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An ACE2 Microbody Containing a Single Immunoglobulin Fc Domain Is a Potent Inhibitor of SARS-CoV-2
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    ncbi.nlm.nih.gov/pmc/articles/PMC7705358/
  118. Sep 2020
  119. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
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    sciencedirect.com/science/article/pii/S153561081930577X
  120. www.sciencedirect.com www.sciencedirect.com
    An Optimized Protocol for Human Direct Cardiac Reprogramming
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    sciencedirect.com/science/article/pii/S2666166719300103
  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Three-Dimensional Alzheimer’s Disease Cell Culture Model Using iPSC-Derived Neurons Carrying A246E Mutation in PSEN1
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    ncbi.nlm.nih.gov/pmc/articles/PMC7325960/
  122. Jan 2020
  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC6584702/
  124. www.jbc.org www.jbc.org
    The RING-type E3 ligase RNF186 ubiquitinates Sestrin-2 and thereby controls nutrient sensing
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    jbc.org/content/294/45/16527.full