53 Matching Annotations
  1. Nov 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    USP9X-triggered ferroptosis mediates follicular atresia via deubiquitinating Beclin1 in chicken
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12548185/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    USP2-mediated PPARγ stabilization promotes hepatocellular carcinoma progression and M2 macrophage polarization via oleic acid
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12588028/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Crimean-Congo hemorrhagic fever virus NSm protein inhibits the type I interferon signaling by binding to STAT2
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12594364/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    UBE2O, a host ubiquitin-conjugating enzyme, is a key regulator of hepatitis B virus maturation and egress
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12554184/
  6. Sep 2025
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Novel Role of the Epstein-Barr Virus Encoded Deubiquitinating Enzyme (BPLF1) in mTOR-Mediated Cell Growth and Proliferation Pathways
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    pmc.ncbi.nlm.nih.gov/articles/PMC12390678/
  8. Jul 2025
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The E3 ubiquitin ligase DTX3L and the deubiquitinase USP28 fine-tune DNA repair through mutual regulation of their protein levels
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12283747/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HDAC6 and USP9X Control Glutamine Metabolism by Stabilizing GS to Promote Glioblastoma Tumorigenesis
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12224959/
  11. Jun 2025
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Reciprocal Regulation Between the SCFFBXO24 Ubiquitin E3 Ligase and FoxP1 Protein
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12154790/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The E3 ubiquitin ligase MARCH2 controls TNF-α mediated inflammation by autoubiquitination
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12126869/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SDCBP/Syntenin-1 stabilizes BACH1 by disassembling the SCFFBXO22–BACH1 complex in triple-negative breast cancer
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12130529/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Exploring Negative Feedback Mechanisms in the PTEN-ACE Axis: Application of Electrosorb Hydrogel-Based Gene Delivery for Intervertebral Disc Regeneration
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12160554/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NUDT16 enhances the resistance of cancer cells to DNA-damaging agents by regulating replication fork stability via reversing HMGA1 ADP-ribosylation
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12151214/
  17. May 2025
  18. elifesciences.org elifesciences.org
    SIRT2-mediated ACSS2 K271 deacetylation suppresses lipogenesis under nutrient stress
    1
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    elifesciences.org/articles/97019
  19. www.sciencedirect.com www.sciencedirect.com
    HSPA9 contributes to tumor progression and ferroptosis resistance by enhancing USP14-driven SLC7A11 deubiquitination in multiple myeloma
    1
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    sciencedirect.com/science/article/pii/S2211124725004917
  20. Apr 2025
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CUL1-neddylation contributes to K29-linked ubiquitination on p27 for autophagic degradation in sorafenib-resistant liver cancer
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11926008/
  22. Feb 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The E3 ubiquitin ligase MAEA promotes macrophage phagocytosis and inhibits gastrointestinal cancer progression by mediating PARP1 ubiquitination and degradation
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11844278/
  24. www.sciencedirect.com www.sciencedirect.com
    Deubiquitinase USP9X controls Wnt signaling for CNS vascular formation and barrier maintenance
    1
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    sciencedirect.com/science/article/pii/S1534580725000292
  25. Jan 2025
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pellino 3 E3 ligase promotes starvation-induced autophagy to prevent hepatic steatosis
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11740972/
  27. Sep 2024
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP5 Promotes Ripretinib Resistance in Gastrointestinal Stromal Tumors by MDH2 Deubiquition
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11425886/
  29. www.sciencedirect.com www.sciencedirect.com
    HSV-1-induced N6-methyladenosine reprogramming via ICP0-mediated suppression of METTL14 potentiates oncolytic activity in glioma
    1
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    sciencedirect.com/science/article/pii/S2211124724011070
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PITAR, a DNA damage-inducible cancer/testis long noncoding RNA, inactivates p53 by binding and stabilizing TRIM28 mRNA
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11415074/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting SNRNP200-induced splicing dysregulation offers an immunotherapy opportunity for glycolytic triple-negative breast cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11405407/
  32. Aug 2024
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cellular turnover and degradation of the most common missense cystathionine beta‐synthase variants causing homocystinuria
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11264351/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Suppression of Skp2 contributes to sepsis-induced acute lung injury by enhancing ferroptosis through the ubiquitination of SLC3A2
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11335248/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    UBR1 promotes anaplastic thyroid carcinoma progression via stabilizing YAP through monoubiquitylation
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11341911/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Periodic changes of cyclin D1 mRNA stability are regulated by PC4 modifications in the cell cycle
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10864110/
  37. 52.53.155.43 52.53.155.43
    FEBS Press
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    52.53.155.43/5ae378afd9ab5ca0cc44c821394ffd9a004fa694/Molecular Oncology - 2023 - Celada-html.html
  38. Jul 2024
  39. www.sciencedirect.com www.sciencedirect.com
    PELI2 is a negative regulator of STING signaling that is dynamically repressed during viral infection
    1
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    sciencedirect.com/science/article/pii/S1097276524004799
  40. Jun 2024
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proximal protein landscapes of the type I interferon signaling cascade reveal negative regulation by PJA2
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11130243/
  42. May 2024
  43. www.sciencedirect.com www.sciencedirect.com
    Ubiquitin-mediated regulation of APE2 protein abundance
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    sciencedirect.com/science/article/pii/S0021925824018386
  44. Apr 2024
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oncolytic Newcastle disease virus induced degradation of YAP through E3 ubiquitin ligase PRKN to exacerbate ferroptosis in tumor cells
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10949840/
  46. Mar 2024
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNF166 promotes colorectal cancer progression by recognizing and destabilizing poly-ADP-ribosylated angiomotins
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10937711/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The dePARylase NUDT16 promotes radiation resistance of cancer cells by blocking SETD3 for degradation via reversing its ADP-ribosylation
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10926213/
  49. www.biorxiv.org www.biorxiv.org
    SIRT2-Mediated ACSS2 K271 Deacetylation Suppresses Lipogenesis Under Nutrient Stress
    1
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    biorxiv.org/content/10.1101/2024.02.27.582293v1
  50. Feb 2024
  51. www.sciencedirect.com www.sciencedirect.com
    The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs
    1
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    sciencedirect.com/science/article/pii/S1097276524000480
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An apicoplast-localized deubiquitinase contributes to the cell growth and apicoplast homeostasis of Toxoplasma gondii
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10795397/
  53. Dec 2023
  54. www.sciencedirect.com www.sciencedirect.com
    FLOT2 promotes nasopharyngeal carcinoma progression through suppression of TGF-β pathway via facilitating CD109 expression
    1
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    sciencedirect.com/science/article/pii/S2589004223026573
  55. Nov 2023
  56. link.springer.com link.springer.com
    SARS-CoV-2 ORF6 protein targets TRIM25 for proteasomal degradation to diminish K63-linked RIG-I ubiquitination and type-I interferon induction
    1
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    link.springer.com/article/10.1007/s00018-023-05011-3
  57. Sep 2023
  58. www.sciencedirect.com www.sciencedirect.com
    Usp25-Erlin1/2 activity limits cholesterol flux to restrict virus infection
    1
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    sciencedirect.com/science/article/pii/S1534580723004094
  59. Jun 2023
  60. www.sciencedirect.com www.sciencedirect.com
    KLHL7 promotes hepatocellular carcinoma progression and molecular therapy resistance by degrading RASA2
    1
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    sciencedirect.com/science/article/pii/S2589004223009914
  61. Mar 2023
  62. www.sciencedirect.com www.sciencedirect.com
    Fam72a functions as a cell-cycle-controlled gene during proliferation and antagonizes apoptosis through reprogramming PP2A substrates
    1
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    sciencedirect.com/science/article/pii/S1534580723000485
  63. Dec 2022
  64. www.sciencedirect.com www.sciencedirect.com
    Fyn deficiency inhibits oxidative stress by decreasing c-Cbl-mediated ubiquitination of Sirt1 to attenuate diabetic renal fibrosis
    1
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    sciencedirect.com/science/article/pii/S0026049522002566
  65. Mar 2022
  66. www.sciencedirect.com www.sciencedirect.com
    K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy
    1
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    sciencedirect.com/science/article/pii/S2211124722000705
  67. Jan 2022
  68. www.sciencedirect.com www.sciencedirect.com
    Gentiopicroside targets PAQR3 to activate PI3K/AKT signaling pathway and ameliorate glucose and lipid metabolism
    1
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    sciencedirect.com/science/article/pii/S2211383521004949
  69. Oct 2021
  70. www.sciencedirect.com www.sciencedirect.com
    Peli1 facilitates NLRP3 inflammasome activation by mediating ASC ubiquitination
    1
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    sciencedirect.com/science/article/pii/S2211124721013747
  71. Jul 2021
  72. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
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    sciencedirect.com/science/article/pii/S1074761319300378
  73. Dec 2020
  74. www.mdpi.com www.mdpi.com
    Hepatitis B Core Protein Is Post-Translationally Modified through K29-Linked Ubiquitination
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    mdpi.com/2073-4409/9/12/2547/htm
  75. Sep 2020
  76. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14853
  77. www.sciencedirect.com www.sciencedirect.com
    L ARP7 Is a BRCA1 Ubiquitinase Substrate and Regulates Genome Stability and Tumorigenesis
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    sciencedirect.com/science/article/pii/S2211124720309554
  78. www.sciencedirect.com www.sciencedirect.com
    OTUB1 Is a Key Regulator of RIG-I-Dependent Immune Signaling and Is Targeted for Proteasomal Degradation by Influenza A NS1
    1
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    sciencedirect.com/science/article/pii/S2211124720300243
  79. Jan 2020
  80. elifesciences.org elifesciences.org
    Nedd4 E3 ligase and beta-arrestins regulate ubiquitination, trafficking, and stability of the mGlu7 receptor
    1
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    elifesciences.org/articles/44502
  81. link.springer.com link.springer.com
    β-TrCP-mediated ubiquitination and degradation of Dlg5 regulates hepatocellular carcinoma cell proliferation
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    link.springer.com/article/10.1186/s12935-019-1029-1
  82. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S1074761319300378