174 Matching Annotations
  1. Jun 2026
  2. www.sciencedirect.com www.sciencedirect.com
    Annexin A6 controls multi-organelle contact site formation and endolysosomal positioning, and remodels the STARD3 interactome
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    sciencedirect.com/science/article/pii/S2589004226017621
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DNER drives glycolytic reprogramming in renal cell carcinoma by activating the JAK2/STAT3 signaling pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC13236898/
  4. www.nature.com www.nature.com
    Autophagic cell death restricts chromosomal instability during replicative crisis
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    nature.com/articles/s41586-019-0885-0
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    DHODH regulates trophoblast fusion via IFITM-reduced plasma membrane fluidity: Implications for hypertensive disorders of pregnancy
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    sciencedirect.com/science/article/pii/S2589004226015385
  6. www.sciencedirect.com www.sciencedirect.com
    mRNA 3′ UTRs chaperone intrinsically disordered regions to control protein activity
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    sciencedirect.com/science/article/pii/S0092867426005763
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    WDR44 drives de novo α-synuclein aggregation at the lysosomal membrane and promotes neuronal dysfunction in Parkinson’s Disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC13081842/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CXCL16-driven CD4+ T cells orchestrate immunosurveillance against MHC-I-deficient hepatocellular tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC13182305/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    mSWI/SNF complex inhibition sensitizes KRAS-mutant lung cancers to targeted therapies via epithelial-mesenchymal subversion
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    pmc.ncbi.nlm.nih.gov/articles/PMC13160128/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ACSS2 Suppresses Ferroptosis to Drive Breast Cancer Brain Metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13195636/
  11. May 2026
  12. www.sciencedirect.com www.sciencedirect.com
    Human Immunodeficiency Virus Type 2 Vpx-mediated Degradation of TASOR Activates Innate Immune Sensing of Nucleic Acids in Infected Cells
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    sciencedirect.com/science/article/pii/S0022283626002524
  13. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.70375
  14. dx.doi.org dx.doi.org
    Fundamental and unique roles of PLAC1 in the regulation of rat and human trophoblast cell development
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    dx.doi.org/10.1242/dev.205290
  15. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70579
  16. link.springer.com link.springer.com
    Autophagy-lysosomal dependency defines a vulnerable physiological state in drug-tolerant persister cells of triple-negative breast cancer
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    link.springer.com/article/10.1007/s10495-026-02310-5
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mitochondrial ETF insufficiency drives neoplastic growth by selectively optimizing cancer bioenergetics
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    pmc.ncbi.nlm.nih.gov/articles/PMC13143275/
  18. Apr 2026
  19. onlinelibrary.wiley.com onlinelibrary.wiley.com
    BCR–ABL1 Drives Transcriptional Reprogramming of Chronic Myeloid Leukemia Cells for Immune Evasion Through C/EBPβ
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    onlinelibrary.wiley.com/doi/10.1002/mco2.70747
  20. www.biorxiv.org www.biorxiv.org
    Sacituzumab Govitecan as an Effective Strategy for Sensitizing Chemoresistant HNSCC Cells to Senolytic Intervention
    1
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    biorxiv.org/content/10.64898/2026.04.13.718209v1
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    WDR44 drives de novo α-synuclein aggregation at the lysosomal membrane and promotes neuronal dysfunction in Parkinson’s Disease
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC13081842/
  22. www.sciencedirect.com www.sciencedirect.com
    Electromagnetic field-inducible in vivo gene switch for remote spatiotemporal control of gene expression
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    sciencedirect.com/science/article/pii/S0092867426003302
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FOXO1 transcription factor modulates airway epithelial responses to viral infection
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    pmc.ncbi.nlm.nih.gov/articles/PMC13048417/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    1-s2.0-S2589004226009855-main-html.html
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    pmc.ncbi.nlm.nih.gov/articles/PMC13138062/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Endogenous retroviral elements LTR8B and MER65 rewire PSG9 regulation to control trophoblast syncytialization and pre-eclampsia risk
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    pmc.ncbi.nlm.nih.gov/articles/PMC12969887/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Insulin and Insulin-like Growth Factor 1 Signaling as a Modulator of MYC Expression in the Meibomian Gland
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    pmc.ncbi.nlm.nih.gov/articles/PMC13024306/
  27. Mar 2026
  28. www.biorxiv.org www.biorxiv.org
    ZNF423 depletion induces the integrated stress response and represents a potential vulnerability in NF1-associated MPNST
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    biorxiv.org/content/10.64898/2026.03.03.709360v1
  29. Feb 2026
  30. www.sciencedirect.com www.sciencedirect.com
    ASCL1 promotes nuclear shrinkage in transdifferentiation by suppressing NUP37
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    sciencedirect.com/science/article/pii/S2213671126000342
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Estrogen Production in Pancreatic Cancer Shapes a Tumor Suppressive Stromal Microenvironment
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    pmc.ncbi.nlm.nih.gov/articles/PMC12862343/
  32. www.sciencedirect.com www.sciencedirect.com
    A neuron subtype-specific role of MEK-ERK signaling in axon survival via transcriptional regulation of Nmnat2
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    sciencedirect.com/science/article/pii/S2211124726000094
  33. Jan 2026
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    REV7 associates with ATRIP and inhibits ATR kinase activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12820532/
  35. www.sciencedirect.com www.sciencedirect.com
    Preclinical drug screen identifies WEE1 inhibitor and vinca alkaloid as a combination treatment concept for Li-Fraumeni syndrome medulloblastoma
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    sciencedirect.com/science/article/pii/S2589004225028251
  36. Dec 2025
  37. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Context-dependent inhibitory roles of RhoA in 3D invasive cell migration within the extracellular matrix
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    sciencedirect.com:5037/science/article/pii/S2211124725014214
  38. Nov 2025
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Resistance to radiation enhances metastasis by altering RNA metabolism
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    pmc.ncbi.nlm.nih.gov/articles/PMC12533556/
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NRDE2 Interacts with an Early Transcription Elongation Complex and Widely Impacts Gene Expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12524662/
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting SQLE-mediated cholesterol metabolism to enhance CD8+ T cell activation and immunotherapy efficacy in hepatocellular carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12481379/
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Rab10 inactivation promotes AMPAR trafficking and spine enlargement during long-term potentiation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12456950/
  43. www.nature.com www.nature.com
    Remodeling of calcium signaling and store operated calcium entry as a consequence of human neural progenitor cell differentiation
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    nature.com/articles/s41598-025-22675-y
  44. Oct 2025
  45. www.sciencedirect.com www.sciencedirect.com
    HUWE1 stimulates mTORC1 activity by enhancing Rheb interaction with mTORC1 and supports de novo pyrimidine synthesis
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    sciencedirect.com/science/article/pii/S2211124725011532
  46. www.biorxiv.org www.biorxiv.org
    Angiopoietin like protein 3 regulates low-density lipoprotein transport through aortic endothelial cells via endothelial lipase
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    biorxiv.org/content/10.1101/2025.09.30.679508v1
  47. Sep 2025
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12420363/
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NCOA6 knockdown enhances RSL3-induced ferroptosis in pancreatic cancer cells and increases the sensitivity to gemcitabine : NCOA6 knockdown and RSL3-induced ferroptosis in pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12368539/
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PBK Expression Promotes the Aggressive Phenotypes of Mesothelioma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12400060/
  51. www.sciencedirect.com www.sciencedirect.com
    Disrupting mitochondrial dynamics attenuates ferroptosis and chemotoxicity via upregulating NRF2-mediated FSP1 expression
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    sciencedirect.com/science/article/pii/S2211124725010058
  52. Aug 2025
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The HCMV tegument protein UL88 degrades MyD88 and reduces innate immune activation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12363176/
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SGK1 repression by WT1 may confer a survival advantage to leukemic cells under stress conditions
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    pmc.ncbi.nlm.nih.gov/articles/PMC12334445/
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting mitochondrial phosphatidylethanolamine alters mitochondrial metabolism and proliferation in hepatocellular carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12288522/
  56. Jul 2025
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of Predicted Cell Adhesion Molecule MPZL3 Promotes EMT in Ovarian Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12277487/
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A novel β-TrCP1/NRF2 interaction inhibitor for effective anti-inflammatory therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12247323/
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BLID is a drug-responsive target of FOXO3a and multi-omics analysis reveals survival mechanisms and therapeutic vulnerabilities in BLID-deficient breast cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12217432/
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrated bioinformatics and experimental validation identify ATF3 as a key gene in secondary brain damage after intracerebral hemorrhage
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    pmc.ncbi.nlm.nih.gov/articles/PMC12273966/
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Knockdown of USF1 and USF2 drives prolonged changes in the gene expression response of M12-5B3 cells to DNA damage
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    pmc.ncbi.nlm.nih.gov/articles/PMC12258588/
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    mRNA 3′UTRs chaperone intrinsically disordered regions to control protein activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12236501/
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sphingolipid synthesis maintains nuclear membrane integrity and genome stability during cell division
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    pmc.ncbi.nlm.nih.gov/articles/PMC12237252/
  64. journals.asm.org journals.asm.org
    The HCMV tegument protein UL88 degrades MyD88 and reduces innate immune activation
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    journals.asm.org/doi/10.1128/jvi.00414-25
  65. www.sciencedirect.com www.sciencedirect.com
    TRIM24 directs replicative stress responses to maintain ALT telomeres via chromatin signaling
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    sciencedirect.com/science/article/pii/S109727652500509X
  66. Jun 2025
  67. www.sciencedirect.com www.sciencedirect.com
    Dynamic decoding of VEGF signaling and coordinated control of multiple phenotypes by the Src-TEM4-YAP pathway
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    sciencedirect.com/science/article/pii/S2405471225001541
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrative multi-omics identifies AP-1 transcription factor as a targetable mediator of acquired osimertinib resistance in non-small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12104440/
  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Stromal Hedgehog Signaling Is Associated with Favorable Outcomes in Pancreatic Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12154493/
  70. www.sciencedirect.com www.sciencedirect.com
    Regulation of Rho guanine nucleotide exchange factor 3 by phosphorylation in the PH domain
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    sciencedirect.com/science/article/pii/S2589004225010144
  71. May 2025
  72. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    EYA3 regulation of NF-κB and CCL2 suppresses cytotoxic NK cells in the premetastatic niche to promote TNBC metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12057687/
  73. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The retinoblastoma protein contributes to maintaining the stability of HPV E7 in cervical cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11998531/
  74. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ATF6α inhibits ΔNp63α expression to promote breast cancer metastasis by the GRP78-AKT1-FOXO3a signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC11994819/
  75. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Changes in adrenoceptor expression level contribute to the cellular plasticity of glioblastoma cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12002996/
  76. Apr 2025
  77. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GATAD2B O-GlcNAcylation Regulates Breast Cancer Stem-like Potential and Drug Resistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC11941746/
  78. www.science.org www.science.org
    Drosophila and human Headcase define a new family of ribonucleotide granule proteins required for stress response
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    science.org/doi/10.1126/sciadv.ads2086
  79. www.sciencedirect.com www.sciencedirect.com
    Versatile roles of annexin A4 in clear cell renal cell carcinoma: Impact on membrane repair, transcriptional signatures, and composition of the tumor microenvironment
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    sciencedirect.com/science/article/pii/S2589004225004596
  80. Mar 2025
  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Heat shock protein family D member 1 mediates lung cancer cell‑induced angiogenesis of endothelial cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11904756/
  82. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Resistance to Radiation Enhances Metastasis by Altering RNA Metabolism
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    pmc.ncbi.nlm.nih.gov/articles/PMC11888214/
  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Screening Methods to Discover the FDA-Approved Cancer Drug Encorafenib as Optimally Selective for Metallothionein Gene Loss Ovarian Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11764637/
  84. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HCMV infection downregulates GPX4 and stimulates lipid peroxidation but does not induce ferroptosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11852782/
  85. www.biorxiv.org www.biorxiv.org
    Cardiolipin deficiency disrupts CoQ-complex III interface in steatohepatitis
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    biorxiv.org/content/10.1101/2024.10.10.617517v3
  86. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ACSS2 drives senescence-associated secretory phenotype by limiting purine biosynthesis through PAICS acetylation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11871226/
  87. Feb 2025
  88. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    T3SS translocon induces pyroptosis by direct interaction with NLRC4/NAIP inflammasome
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    pmc.ncbi.nlm.nih.gov/articles/PMC11828483/
  89. Jan 2025
  90. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The oxygen level in air directs airway epithelial cell differentiation by controlling mitochondrial citrate export
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    pmc.ncbi.nlm.nih.gov/articles/PMC11759043/
  91. www.nature.com www.nature.com
    Homologous recombination promotes non-immunogenic mitotic cell death upon DNA damage
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    nature.com/articles/s41556-024-01557-x
  92. Dec 2024
  93. www.sciencedirect.com www.sciencedirect.com
    TurboCas: A method for locus-specific labeling of genomic regions and isolating their associated protein interactome
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    sciencedirect.com/science/article/pii/S1097276524009122
  94. www.sciencedirect.com www.sciencedirect.com
    The Cullin3-Rbx1-KLHL9 E3 ubiquitin ligase complex ubiquitinates Rheb and supports amino acid-induced mTORC1 activation
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    sciencedirect.com/science/article/pii/S2211124724014529
  95. www.sciencedirect.com www.sciencedirect.com
    Lnc-RAINY Regulates Genes Involved in Radiation Susceptibility Through DNA:DNA:RNA triplex-forming Interactions and has Tumor Therapeutic Potential in Lung Cancers
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    sciencedirect.com/science/article/pii/S2468054024001689
  96. Nov 2024
  97. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ubiquitin C-terminal hydrolase L1 is a regulator of tumor growth and metastasis in double-negative prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11578776/
  98. Sep 2024
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Type I interferon signaling induces melanoma cell-intrinsic PD-1 and its inhibition antagonizes immune checkpoint blockade
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    ncbi.nlm.nih.gov/pmc/articles/PMC11347607/
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Superoxide dismutase 1 mediates adaptation to the tumor microenvironment of glioma cells via mammalian target of rapamycin complex 1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11347576/
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cysteine-rich with EGF-like domains 2 (CRELD2) is an endoplasmic reticulum stress-inducible angiogenic growth factor promoting ischemic heart repair
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    ncbi.nlm.nih.gov/pmc/articles/PMC11358006/
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Altering heparan sulfate suppresses cell abnormalities and neuron loss in Drosophila presenilin model of Alzheimer Disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC11302002/
  103. www.sciencedirect.com www.sciencedirect.com
    mCAUSE: Prioritizing Mitochondrial Targets that Alleviate Pancreatic Cancer Cell Phenotypes
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    sciencedirect.com/science/article/pii/S2589004224021059
  104. Aug 2024
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    De Novo Multi-Omics Pathway Analysis Designed for Prior Data Independent Inference of Cell Signaling Pathways
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    ncbi.nlm.nih.gov/pmc/articles/PMC11259815/
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BMAL1-HIF2α heterodimers contribute to ccRCC
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  139. Mar 2024
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  170. Feb 2023
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  179. Jun 2022
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  196. Sep 2021
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  198. Aug 2021
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  203. Jul 2021
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  205. Jun 2021
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  208. May 2021
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  212. Apr 2021
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  214. Mar 2021
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  216. Feb 2021
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  218. Nov 2020
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  222. Sep 2020
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  229. Jan 2020
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    Suppressing Aneuploidy-Associated Phenotypes Improves the Fitness of Trisomy 21 Cells
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    sciencedirect.com/science/article/pii/S2211124719313737
  231. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6286125/
  232. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial Stasis Reveals p62-Mediated Ubiquitination in Parkin-Independent Mitophagy and Mitigates Nonalcoholic Fatty Liver Disease
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    sciencedirect.com/science/article/pii/S1550413118303966