Hypothesis

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Aug 2025
www.biorxiv.org www.biorxiv.org

Endocytic control of cell-autonomous and non-cell-autonomous functions of p53

1
1. scibot 27 Aug 2025
  
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  RRID:Addgene_19119
  
  DOI: 10.1101/2025.08.16.670648
  
  Resource: RRID:Addgene_19119
  
  Curator: @scibot
  
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biorxiv.org/content/10.1101/2025.08.16.670648v1
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Reversible proliferative arrest induced by rapid depletion of RNase MRP

1
1. scibot 20 Jul 2025
  
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  19119
  
  DOI: 10.1038/s41467-025-60471-4
  
  Resource: RRID:Addgene_19119
  
  Curator: @olekpark
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12177063/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Anticancer Quinolinol Small Molecules Target Multiple Pathways to Promote Cell Death and Eliminate Melanoma Cells Resistant to BRAF Inhibitors

1
1. scibot 13 Jul 2025
  
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  Plasmid_19119
  
  DOI: 10.3390/molecules30132696
  
  Resource: RRID:Addgene_19119
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12251381/
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Suppression of stress granule formation is a vulnerability imposed by mutant p53

1
1. scibot 23 Mar 2025
  
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  19119
  
  DOI: 10.1038/s41467-025-57539-6
  
  Resource: RRID:Addgene_19119
  
  Curator: @olekpark
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11894096/
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Novel Inhibitors for MDM2-MDM4 E3 Ligase Potently Induce p53-Indepedent Apoptosis in Drug-Resistant Leukemic Cells

1
1. scibot 27 Jan 2025
  
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  Plasmid_19119
  
  DOI: 10.3390/molecules30010186
  
  Resource: RRID:Addgene_19119
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11722259/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Sumo-regulatory SENP2 controls the homeostatic squamous mitosis-differentiation checkpoint

1
1. scibot 21 Aug 2024
  
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  19119
  
  DOI: 10.1038/s41419-024-06969-z
  
  Resource: RRID:Addgene_19119
  
  Curator: @olekpark
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11329632/
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

APR-246 as a radiosensitization strategy for mutant p53 cancers treated with alpha-particles-based radiotherapy

1
1. scibot 30 Jun 2024
  
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  pLKO.1-puro-shp53
  
  DOI: 10.1038/s41419-024-06830-3
  
  Resource: RRID:Addgene_19119
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_19119
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11189442/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Atypical cell cycle regulation promotes mammary stem cell expansion during mammary development and tumourigenesis

1
1. scibot 30 Jun 2024
  
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  RRID:Addgene_19119
  
  DOI: 10.1186/s13058-024-01862-1
  
  Resource: RRID:Addgene_19119
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11212383/
Mar 2024
www.biorxiv.org www.biorxiv.org

Atypical Cell Cycle Regulation Promotes Mammary Stem Cell Expansion and Therapeutic Resistance

1
1. scibot 15 Mar 2024
  
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  RRID:Addgene_19119
  
  DOI: 10.1101/2024.03.05.583524
  
  Resource: RRID:Addgene_19119
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_19119
  
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biorxiv.org/content/10.1101/2024.03.05.583524v1
www.nature.com www.nature.com

AF1q is a universal marker of neuroblastoma that sustains N-Myc expression and drives tumorigenesis

1
1. scibot 01 Mar 2024
  
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  RRID:Addgene_19119
  
  DOI: 10.1038/s41388-024-02980-y
  
  Resource: RRID:Addgene_19119
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_19119
  
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nature.com/articles/s41388-024-02980-y
Feb 2023
www.sciencedirect.com www.sciencedirect.com

Injury primes mutation-bearing astrocytes for dedifferentiation in later life

1
1. scibot 25 Feb 2023
  
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  RRID:Addgene_19119
  
  DOI: 10.1016/j.cub.2023.02.013
  
  Resource: RRID:Addgene_19119
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_19119
  
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sciencedirect.com/science/article/pii/S0960982223001525
Feb 2022
www.sciencedirect.com www.sciencedirect.com

RAP80 suppresses the vulnerability of R-loops during DNA double-strand break repair

1
1. scibot 02 Feb 2022
  
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  Addgene 19119
  
  DOI: 10.1016/j.celrep.2022.110335
  
  Resource: RRID:Addgene_19119
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:Addgene_19119
  
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sciencedirect.com/science/article/pii/S2211124722000511
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Increased p53 signaling impairs neural differentiation in HUWE1-promoted intellectual disabilities

1
1. scibot 09 Apr 2021
  
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  19119
  
  DOI: 10.1016/j.xcrm.2021.100240
  
  Resource: RRID:Addgene_19119
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_19119
  
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  RRID:Addgene_19119 RRIDCUR:Missing
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RRID:Addgene_19119

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scibot

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sciencedirect.com/science/article/pii/S2666379121000562