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Uncovering NMDA receptor-mediated high firing activity in excitatory human neurons

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1. scibot 25 Mar 2026
  
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  19780
  
  DOI: 10.1016/j.isci.2026.115061
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12997311/
Nov 2025
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Genetic and proteomic analysis identifies BAG3 as an amyloid-responsive regulator of neuronal proteostasis

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1. scibot 24 Nov 2025
  
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  plasmid_19780
  
  DOI: 10.1007/s00401-025-02947-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12521299/
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The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases

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1. scibot 23 Nov 2025
  
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  DOI: 10.1038/s42255-025-01365-z
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12552125/
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SARS-CoV-2 infection in hiPSC-derived neurons is cathepsin-dependent and causes differential accumulation of HIF1ɑ and phosphorylated tau

1
1. scibot 23 Nov 2025
  
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  FUdeltaGW-rtTA
  
  DOI: 10.1016/j.omtn.2025.102726
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12597281/
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Neuronal activity-dependent mechanisms of small cell lung cancer pathogenesis

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1. scibot 23 Nov 2025
  
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  DOI: 10.1038/s41586-025-09492-z
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12571889/
Oct 2025
www.sciencedirect.com www.sciencedirect.com

Protocol for generating a human iPSC-derived tri-culture model to study interactions between neurons, astrocytes, and microglia

1
1. scibot 29 Oct 2025
  
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  plasmid_19780
  
  DOI: 10.1016/j.xpro.2025.104152
  
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sciencedirect.com/science/article/pii/S2666166725005581
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Neuronal activity-dependent mechanisms of small cell lung cancer pathogenesis

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1. scibot 16 Sep 2025
  
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  RRID:Addgene_19780
  
  DOI: 10.1038/s41586-025-09492-z
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12571889/
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Optineurin deficiency disrupts phosphorylated tau proteostasis and clusterin expression in human neurons

1
1. scibot 07 Sep 2025
  
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  plasmid_19780
  
  DOI: 10.1186/s40478-025-02103-y
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12406597/
Jul 2025
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An improved immunoassay detects Aβ oligomers in human biofluids: their CSF levels rise with tau and phosphotau levels

1
1. scibot 20 Jul 2025
  
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  plasmid_19
  
  DOI: 10.1186/s13195-025-01802-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12255133/
Jun 2025
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Experimental evidence that readily diffusible forms of Aβ from Alzheimer’s disease brain have seeding activity

1
1. scibot 15 Jun 2025
  
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  plasmid_1978
  
  DOI: 10.1186/s40478-025-02032-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12102860/
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Astrocyte induction of disease-associated microglia is suppressed by acute exposure to fAD neurons in human iPSC triple cultures

1
1. scibot 05 Jun 2025
  
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  plasmid_19780
  
  DOI: 10.1016/j.celrep.2025.115777
  
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sciencedirect.com/science/article/pii/S2211124725005480
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Ubiquitous MEIS transcription factors actuate lineage-specific transcription to establish cell fate

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1. scibot 19 May 2025
  
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  Addgene_19780
  
  DOI: 10.1038/s44318-025-00385-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12000411/
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CLU alleviates Alzheimer’s disease-relevant processes by modulating astrocyte reactivity and microglia-dependent synaptic density

1
1. scibot 18 May 2025
  
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  plasmid_19780
  
  DOI: 10.1016/j.neuron.2025.03.034
  
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sciencedirect.com/science/article/pii/S0896627325002545
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

HAND1 level controls the specification of multipotent cardiac and extraembryonic progenitors from human pluripotent stem cells

1
1. scibot 17 May 2025
  
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  DOI: 10.1038/s44318-025-00409-0
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12048643/
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Contributions of Genetic Variation in Astrocytes to Cell and Molecular Mechanisms of Risk and Resilience to Late‐Onset Alzheimer's Disease

1
1. scibot 16 May 2025
  
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  plasmid_19780
  
  DOI: 10.1002/glia.24677
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12012329/
Mar 2025
www.biorxiv.org www.biorxiv.org

Protective ApoE variants support neuronal function by extracting peroxidated lipids

1
1. scibot 14 Mar 2025
  
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  Addgene_19780
  
  DOI: 10.1101/2025.03.05.641722
  
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biorxiv.org/content/10.1101/2025.03.05.641722v1
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Development and characterization of in vitro inducible immortalization of a murine microglia cell line for high throughput studies

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1. scibot 11 Mar 2025
  
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  DOI: 10.1038/s41598-025-87543-1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11762310/
Feb 2025
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Regulation of ER stress-induced apoptotic and inflammatory responses via YAP/TAZ-mediated control of the TRAIL-R2/DR5 signaling pathway

1
1. scibot 18 Feb 2025
  
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  19780
  
  DOI: 10.1038/s41420-025-02335-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11794427/
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Imaging lipid rafts reveals the principle of ApoE4-induced Aβ upregulation in human neurons

1
1. scibot 11 Feb 2025
  
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  RRID:Addgene_19780
  
  DOI: 10.1016/j.isci.2025.111893
  
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sciencedirect.com/science/article/pii/S2589004225001531
Dec 2024
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KIF5A regulates axonal repair and time-dependent axonal transport of SFPQ granules and mitochondria in human motor neurons

1
1. scibot 10 Dec 2024
  
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  Addgene_19780
  
  DOI: 10.1016/j.nbd.2024.106759
  
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sciencedirect.com/science/article/pii/S0969996124003619
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

KIF5A regulates axonal repair and time-dependent axonal transport of SFPQ granules and mitochondria in human motor neurons

1
1. scibot 28 Sep 2024
  
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  Addgene_19780
  
  DOI: 10.1101/2024.09.06.611684
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11418931/
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A single-cell transcriptomic dataset of pluripotent stem cell-derived astrocytes via NFIB/SOX9 overexpression

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1. scibot 13 Sep 2024
  
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  Addgene_19780
  
  DOI: 10.1038/s41597-024-03823-x
  
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nature.com/articles/s41597-024-03823-x
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Protocol for neurogenin-2-mediated induction of human stem cell-derived neural progenitor cells

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1. scibot 02 Aug 2024
  
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  19780
  
  DOI: 10.1016/j.xpro.2024.102878
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10865475/
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

KDM5-mediated transcriptional activation of ribosomal protein genes alters translation efficiency to regulate mitochondrial metabolism in neurons

1
1. scibot 30 Jun 2024
  
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  RRID:Addgene_19780
  
  DOI: 10.1093/nar/gkae261
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11194071/
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mutations in the postsynaptic density signaling hub TNIK disrupt PSD signaling in human models of neurodevelopmental disorders

1
1. scibot 23 Apr 2024
  
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  19780
  
  DOI: 10.3389/fnmol.2024.1359154
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11024424/
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Insulin signalling regulates Pink1 mRNA localization via modulation of AMPK activity to support PINK1 function in neurons

1
1. scibot 15 Apr 2024
  
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  19780
  
  DOI: 10.1038/s42255-024-01007-w
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10963278/
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Defined co-cultures of glutamatergic and GABAergic neurons with a mutation in DISC1 reveal aberrant phenotypes in GABAergic neurons

2
1. scibot 08 Mar 2024
  
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  19780
  
  DOI: 10.1186/s12868-024-00858-z
  
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  RRID:Addgene_19780
2. scibot 08 Mar 2024
  
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  19780
  
  DOI: 10.1186/s12868-024-00858-z
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10910844/
Feb 2024
www.sciencedirect.com www.sciencedirect.com

Proline restores mitochondrial function and reverses aging hallmarks in senescent cells

1
1. scibot 14 Feb 2024
  
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  plasmid_19780
  
  DOI: 10.1016/j.celrep.2024.113738
  
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sciencedirect.com/science/article/pii/S2211124724000664
Oct 2023
www.mdpi.com www.mdpi.com

Role of the YAP/TAZ-TEAD Transcriptional Complex in the Metabolic Control of TRAIL Sensitivity by the Mevalonate Pathway in Cancer Cells

1
1. scibot 14 Oct 2023
  
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  RRID:Addgene_19780
  
  DOI: 10.3390/cells12192370
  
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mdpi.com/2073-4409/12/19/2370
Aug 2023
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Cell-type-specific regulation of APOE and CLU levels in human neurons by the Alzheimer’s disease risk gene SORL1

1
1. scibot 23 Aug 2023
  
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  plasmid_19780
  
  DOI: 10.1016/j.celrep.2023.112994
  
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sciencedirect.com/science/article/pii/S2211124723010057
Jun 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

APOE expression and secretion are modulated by mitochondrial dysfunction

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1. scibot 03 Jun 2023
  
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  RRID:Addgene_19780
  
  DOI: 10.7554/eLife.85779
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10231934/
May 2023
www.biorxiv.org www.biorxiv.org

Upregulated GIRK2 counteracts ethanol-induced changes in excitability and respiration in human neurons

1
1. scibot 05 May 2023
  
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  #19780
  
  DOI: 10.1101/2023.03.22.533236
  
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  Curator: @jmitrevska
  
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biorxiv.org/content/10.1101/2023.03.22.533236v2
Mar 2022
www.nature.com www.nature.com

APP and DYRK1A regulate axonal and synaptic vesicle protein networks and mediate Alzheimer’s pathology in trisomy 21 neurons

1
1. scibot 05 Mar 2022
  
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  plasmid_19780
  
  DOI: 10.1038/s41380-022-01454-5
  
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nature.com/articles/s41380-022-01454-5
Sep 2021
www.sciencedirect.com www.sciencedirect.com

Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors

2
1. scibot 04 Sep 2021
  
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  plasmid # 19780
  
  DOI: 10.1016/j.neuron.2021.08.003
  
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2. scibot 03 Sep 2021
  
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  plasmid_19780
  
  DOI: 10.1016/j.neuron.2021.08.003
  
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sciencedirect.com/science/article/pii/S089662732100578X
Jun 2021
currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com

Efficient Derivation of Excitatory and Inhibitory Neurons from Human Pluripotent Stem Cells Stably Expressing Direct Reprogramming Factors

1
1. scibot 10 Jun 2021
  
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  Addgene_19780
  
  DOI: 10.1002/cpz1.141
  
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currentprotocols.onlinelibrary.wiley.com/doi/10.1002/cpz1.141
Dec 2020
www.sciencedirect.com www.sciencedirect.com

Protocol for Tri-culture of hiPSC-Derived Neurons, Astrocytes, and Microglia

1
1. scibot 07 Dec 2020
  
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  VSVG.HIV.SIN.cPPT.CMV.rTTA.WPRE
  
  DOI: 10.1016/j.xpro.2020.100190
  
  Resource: RRID:Addgene_19780
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_19780
  
  Curator comments: FUdeltaGW-rtTA
  
  What is this?
  
  RRID:Addgene_19780 RRIDCUR:Missing
Visit annotations in context

Tags

RRIDCUR:Missing

RRID:Addgene_19780

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666166720301775
Sep 2020
www.sciencedirect.com www.sciencedirect.com

A Susceptibility Locus on Chromosome 13 Profoundly Impacts the Stability of Genomic Imprinting in Mouse Pluripotent Stem Cells

1
1. scibot 05 Sep 2020
  
  in Public
  
  RRID:Addgene_19780
  
  DOI: 10.1016/j.celrep.2020.02.073
  
  Resource: RRID:Addgene_19780
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_19780
  
  What is this?
  
  RRIDCUR:Validated RRID:Addgene_19780
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:Addgene_19780

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720302424
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment

1
1. scibot 13 Jan 2020
  
  in Public
  
  plasmid_19780
  
  DOI: 10.1016/j.molcel.2018.11.028
  
  Resource: RRID:Addgene_19780
  
  Curator: @Naa003
  
  SciCrunch record: plasmid_19780
  
  What is this?
  
  RRID:Addgene_19780 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:Addgene_19780

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276518309985