40 Matching Annotations
  1. May 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatiotemporally resolved colorectal oncogenesis in mini-colons ex vivo
    1
    1. scibot 12 May 2024
      20342

      DOI: 10.1038/s41586-024-07330-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC11078756/
  3. Apr 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ENGINEERED NANOBODIES WITH PROGRAMMABLE TARGET ANTIGEN PROTEOLYSIS (PTAP) FUSIONS REGULATE INTRACELLULAR ALPHA-SYNUCLEIN IN VITRO AND IN VIVO
    1
    1. scibot 23 Apr 2024
      20342

      DOI: 10.21203/rs.3.rs-4088206/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10996777/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation
    1
    1. scibot 15 Apr 2024
      Addgene_20342

      DOI: 10.7554/eLife.90579

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    ncbi.nlm.nih.gov/pmc/articles/PMC10959535/
  6. www.sciencedirect.com www.sciencedirect.com
    BRCA1 and 53BP1 regulate reprogramming efficiency by mediating DNA repair pathway choice at replication-associated double-strand breaks
    1
    1. scibot 02 Apr 2024
      AddgeneCat# 20342

      DOI: 10.1016/j.celrep.2024.114006

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    sciencedirect.com/science/article/pii/S2211124724003346
  7. Feb 2024
  8. www.sciencedirect.com www.sciencedirect.com
    Direct reprogramming of non-limb fibroblasts to cells with properties of limb progenitors
    1
    1. scibot 06 Feb 2024
      Addgene#20342

      DOI: 10.1016/j.devcel.2023.12.010

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    sciencedirect.com/science/article/pii/S1534580723006901
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-content screening identifies a small molecule that restores AP-4-dependent protein trafficking in neuronal models of AP-4-associated hereditary spastic paraplegia
    1
    1. scibot 01 Feb 2024
      Addgene_20342

      DOI: 10.1038/s41467-023-44264-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10794252/
  10. Dec 2023
  11. www.sciencedirect.com www.sciencedirect.com
    ALDH5A1-deficient iPSC-derived excitatory and inhibitory neurons display cell type specific alterations
    1
    1. scibot 19 Dec 2023
      addgene_20342

      DOI: 10.1016/j.nbd.2023.106386

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    sciencedirect.com/science/article/pii/S0969996123004023
  12. Nov 2023
  13. www.sciencedirect.com www.sciencedirect.com
    An integrated in vitro human iPSCs-derived neuron and in vivo animal approach for preclinical screening of anti-seizure compounds
    1
    1. scibot 28 Nov 2023
      RRID:Addgene_20342

      DOI: 10.1016/j.jare.2023.11.022

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    sciencedirect.com/science/article/pii/S2090123223003612
  14. Oct 2023
  15. www.nature.com www.nature.com
    Chromatin-modifying enzymes as modulators of nuclear size during lineage differentiation
    1
    1. scibot 21 Oct 2023
      RRID:Addgene_20342

      DOI: 10.1038/s41420-023-01639-z

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    nature.com/articles/s41420-023-01639-z
  16. Aug 2023
  17. www.sciencedirect.com www.sciencedirect.com
    Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons
    1
    1. scibot 30 Aug 2023
      RRID:Addgene_20342

      DOI: 10.1016/j.xgen.2023.100399

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    sciencedirect.com/science/article/pii/S2666979X23002136
  18. www.nature.com www.nature.com
    Efficient generation of functional neurons from mouse embryonic stem cells via neurogenin-2 expression
    1
    1. scibot 24 Aug 2023
      plasmid_20342

      DOI: 10.1038/s41596-023-00863-2

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    nature.com/articles/s41596-023-00863-2
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optimized protocol for the generation of functional human induced-pluripotent-stem-cell-derived dopaminergic neurons
    1
    1. scibot 10 Aug 2023
      Addgene_20342

      DOI: 10.1016/j.xpro.2023.102486

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    ncbi.nlm.nih.gov/pmc/articles/PMC10400954/
  20. Apr 2023
  21. www.biorxiv.org www.biorxiv.org
    Pharmacological chaperones restore proteostasis of epilepsy-associated GABAA receptor variants
    1
    1. scibot 27 Apr 2023
      RRID:Addgene_20342

      DOI: 10.1101/2023.04.18.537383

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    biorxiv.org/content/10.1101/2023.04.18.537383v1
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hominoid SVA-lncRNA AK057321 targets human-specific SVA retrotransposons in SCN8A and CDK5RAP2 to initiate neuronal maturation
    1
    1. scibot 04 Apr 2023
      Addgene_20342

      DOI: 10.1038/s42003-023-04683-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC10063665/
  23. Mar 2023
  24. www.biorxiv.org www.biorxiv.org
    SYNGAP1 deficiency disrupts neoteny in human cortical neurons in vivo
    1
    1. scibot 03 Mar 2023
      RRID:Addgene_20342

      DOI: 10.1101/2023.01.14.524054

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    biorxiv.org/content/10.1101/2023.01.14.524054v1
  25. Jan 2023
  26. www.sciencedirect.com www.sciencedirect.com
    Neurotransmitter release progressively desynchronizes in induced human neurons during synapse maturation and aging
    1
    1. scibot 26 Jan 2023
      Addgene_20342

      DOI: 10.1016/j.celrep.2023.112042

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    sciencedirect.com/science/article/pii/S2211124723000530
  27. www.sciencedirect.com www.sciencedirect.com
    Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons
    1
    1. scibot 19 Jan 2023
      RRID:Addgene_20342

      DOI: 10.1016/j.stem.2022.12.010

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    sciencedirect.com/science/article/pii/S1934590922004945
  28. Nov 2022
  29. www.sciencedirect.com www.sciencedirect.com
    Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation
    1
    1. scibot 24 Nov 2022
      RRID:Addgene_20342

      DOI: 10.1016/j.molcel.2022.11.002

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    sciencedirect.com/science/article/abs/pii/S1097276522010644
  30. www.sciencedirect.com www.sciencedirect.com
    Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies
    1
    1. scibot 24 Nov 2022
      Addgene_20342

      DOI: 10.1016/j.celrep.2022.111678

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    sciencedirect.com/science/article/pii/S2211124722015522
  31. Oct 2022
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CASK loss of function differentially regulates neuronal maturation and synaptic function in human induced cortical excitatory neurons
    1
    1. scibot 19 Oct 2022
      Addgene_20342

      DOI: 10.1016/j.isci.2022.105187

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC9574418/
  33. www.sciencedirect.com www.sciencedirect.com
    In vitro neurons learn and exhibit sentience when embodied in a simulated game-world
    1
    1. scibot 13 Oct 2022
      Addgene_20342

      DOI: 10.1016/j.neuron.2022.09.001

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    sciencedirect.com/science/article/pii/S0896627322008066
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration
    1
    1. scibot 02 Oct 2022
      Addgene_20342

      DOI: 10.1016/j.isci.2022.105050

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    ncbi.nlm.nih.gov/pmc/articles/PMC9519511/
  35. Jun 2022
  36. www.sciencedirect.com www.sciencedirect.com
    Mapping cis-regulatory elements in human neurons links psychiatric disease heritability and activity-regulated transcriptional programs
    1
    1. scibot 03 Jun 2022
      RRID:Addgene_20342

      DOI: 10.1016/j.celrep.2022.110877

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    sciencedirect.com/science/article/pii/S2211124722006520
  37. May 2022
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glioblastoma Embryonic-like Stem Cells Exhibit Immune-Evasive Phenotype
    1
    1. scibot 18 May 2022
      RRID:Addgene_20342

      DOI: 10.3390/cancers14092070

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    ncbi.nlm.nih.gov/pmc/articles/PMC9104850/
  39. Nov 2021
  40. www.sciencedirect.com www.sciencedirect.com
    Rapid generation of murine haploid-induced trophoblast stem cells via a Tet-on system
    1
    1. scibot 09 Nov 2021
      Plasmid_20342

      DOI: 10.1016/j.xpro.2021.100881

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    sciencedirect.com/science/article/pii/S2666166721005876
  41. Oct 2021
  42. www.sciencedirect.com www.sciencedirect.com
    A synaptic temperature sensor for body cooling
    1
    1. scibot 21 Oct 2021
      20342

      DOI: 10.1016/j.neuron.2021.10.001

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    sciencedirect.com/science/article/pii/S0896627321007698
  43. Aug 2021
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 12 Aug 2021
      Plasmid_20342

      DOI: 10.1016/j.cell.2016.12.036

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    ncbi.nlm.nih.gov/pmc/articles/PMC5679265/
  45. www.sciencedirect.com www.sciencedirect.com
    Interspecies Chimerism with Mammalian Pluripotent Stem Cells
    1
    1. scibot 07 Aug 2021
      Plasmid_20342

      DOI: 10.1016/j.cell.2016.12.036

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    sciencedirect.com/science/article/pii/S0092867416317524
  46. Jul 2021
  47. www.sciencedirect.com www.sciencedirect.com
    Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses
    1
    1. scibot 30 Jul 2021
      FUW-rtTA (lentiviral vector)

      DOI: 10.1016/j.cell.2019.09.011

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S0092867419310177
  48. www.sciencedirect.com www.sciencedirect.com
    Xenotransplanted Human Cortical Neurons Reveal Species-Specific Development and Functional Integration into Mouse Visual Circuits
    1
    1. scibot 29 Jul 2021
      Addgene:20342

      DOI: 10.1016/j.neuron.2019.10.002

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    sciencedirect.com/science/article/pii/S0896627319308505
  49. www.sciencedirect.com www.sciencedirect.com
    Sox2 and Klf4 as the Functional Core in Pluripotency Induction without Exogenous Oct4
    1
    1. scibot 29 Jul 2021
      Addgene plasmid Cat# 20342

      DOI: 10.1016/j.celrep.2019.10.026

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    sciencedirect.com/science/article/pii/S2211124719313269
  50. www.sciencedirect.com www.sciencedirect.com
    Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment
    1
    1. scibot 28 Jul 2021
      FUW-M2rtTA

      DOI: 10.1016/j.molcel.2018.11.028

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    sciencedirect.com/science/article/pii/S1097276518309985
  51. Jun 2021
  52. www.sciencedirect.com www.sciencedirect.com
    Using the dCas9-KRAB system to repress gene expression in hiPSC-derived NGN2 neurons
    1
    1. scibot 04 Jun 2021
      Plasmid_20342

      DOI: 10.1016/j.xpro.2021.100580

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    sciencedirect.com/science/article/pii/S2666166721002872
  53. May 2021
  54. www.nature.com www.nature.com
    Neuron and astrocyte aggregation and sorting in three-dimensional neuronal constructs
    1
    1. scibot 22 May 2021
      RRID:Addgene_20342

      DOI: 10.1038/s42003-021-02104-2

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    nature.com/articles/s42003-021-02104-2
  55. www.sciencedirect.com www.sciencedirect.com
    Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer’s Disease
    1
    1. scibot 08 May 2021
      Addgene_20342

      DOI: 10.1016/j.neuron.2020.11.002

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    sciencedirect.com/science/article/pii/S0896627320308618
  56. Mar 2021
  57. www.sciencedirect.com www.sciencedirect.com
    H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model
    1
    1. scibot 22 Mar 2021
      RRID:Addgene_20342

      DOI: 10.1016/j.ccell.2021.01.005

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    sciencedirect.com/science/article/pii/S1535610821000490
  58. Feb 2021
  59. elifesciences.org elifesciences.org
    Dyshomeostatic modulation of Ca2+-activated K+ channels in a human neuronal model of KCNQ2 encephalopathy
    1
    1. scibot 11 Feb 2021
      RRID:Addgene_20342

      DOI: 10.7554/eLife.64434

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    elifesciences.org/articles/64434
  60. Dec 2020
  61. www.sciencedirect.com www.sciencedirect.com
    Master Regulators and Cofactors of Human Neuronal Cell Fate Specification Identified by CRISPR Gene Activation Screens
    1
    1. scibot 07 Dec 2020
      Addgene_20342

      DOI: 10.1016/j.celrep.2020.108460

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    sciencedirect.com/science/article/pii/S2211124720314492
  62. Oct 2020
  63. www.embopress.org www.embopress.org
    Identification of a dynamic gene regulatory network required for pluripotency factor‐induced reprogramming of mouse fibroblasts and hepatocytes
    1
    1. scibot 13 Oct 2020
      RRID:Addgene_20342

      DOI: 10.15252/embj.2019102236

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    embopress.org/doi/full/10.15252/embj.2019102236
  64. Jan 2020
  65. www.sciencedirect.com www.sciencedirect.com
    Pioneer Factor NeuroD1 Rearranges Transcriptional and Epigenetic Profiles to Execute Microglia-Neuron Conversion
    1
    1. scibot 13 Jan 2020
      Addgene_20342

      DOI: 10.1016/j.neuron.2018.12.010

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    sciencedirect.com/science/article/pii/S0896627318310869