76 Matching Annotations
  1. Last 7 days
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    TRPML3 and TRPML1/3 differentially regulate unconventional MIF secretion through TMED10 and secretory autophagy
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    tandfonline.com/doi/abs/10.1080/27694127.2026.2740425
  3. Oct 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TRPML3 and TRPML1/3 differentially regulate unconventional MIF secretion through TMED10 and secretory autophagy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13652084/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting the senescence‒autophagy axis via p16INK4a inhibition alleviates pulmonary fibrosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13270108/
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    APOE4-Expressing Astrocytes Exhibit Parkinson’s Disease–Related Pathology
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    pmc.ncbi.nlm.nih.gov/articles/PMC13260029/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    tRNA m2G methyltransferase complex THUMPD3-TRMT112 promotes pancreatic cancer progression and autophagy via modulating TFEB translation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13001353/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    VAMP7-dependent late endosomal secretion of ER and mitochondrial proteins impacts the tumor microenvironment and macrophage engagement
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    pmc.ncbi.nlm.nih.gov/articles/PMC13035943/
  9. Sep 2026
  10. www.nature.com www.nature.com
    PAX9 activates autophagy through a transcription-dependent mechanism, promoting EGFR degradation to restrict cell survival in oral cancer
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    nature.com/articles/s41416-026-03608-6
  11. Aug 2026
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Photon irradiation prompts autophagy in anaplastic thyroid cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13508399/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ERRγ impedes neuroendocrine prostate cancer development
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    pmc.ncbi.nlm.nih.gov/articles/PMC12863258/
  14. Jun 2026
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ULK1-mediated phosphorylation regulates the conserved role of YKT6 in autophagy
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    pmc.ncbi.nlm.nih.gov/articles/PMC10022743/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TLR7 induces autophagy in non-small cell lung cancer tumor cells and influences anti-tumors responses in patients
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    pmc.ncbi.nlm.nih.gov/articles/PMC13186664/
  17. Feb 2026
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Quantitative and temporal analysis of autophagy: Differential Response to amino acid and glucose starvation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12872001/
  19. Jan 2026
  20. www.sciencedirect.com www.sciencedirect.com
    CK1δ-dependent SNAPIN dysregulation drives lysosomal failure in HIV-1 Vpr-exposed neurons: A targetable mechanism in HAND
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    sciencedirect.com/science/article/pii/S2589004225028056
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Obestatin Treatment Counteracts Muscle Wasting by Reactivation of Autophagy in Duchenne Muscular Dystrophy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12803508/
  22. Nov 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mutations in the Key Autophagy Tethering Factor EPG5 Link Neurodevelopmental and Neurodegenerative Disorders Including Early‐Onset Parkinsonism
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    pmc.ncbi.nlm.nih.gov/articles/PMC12577676/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Membrane receptors cluster phosphatidylserine to activate LC3-associated phagocytosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12527911/
  25. Sep 2025
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Two specific interactions of GATE16 with TRPML3 and RAB33B regulate autophagy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12378212/
  27. Aug 2025
  28. www.sciencedirect.com www.sciencedirect.com
    Ridaifen derivatives function as potent lysosomotropic agents, depending on their basic side chains.
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    sciencedirect.com/science/article/pii/S0014299925008362
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    H3K36me2 methyltransferase NSD2/WHSC1 promotes triple-negative breast cancer metastasis via activation of ULK1-dependent autophagy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12283020/
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ANKZF1 helps to eliminate stress-damaged mitochondria by LC3-mediated mitophagy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12307761/
  31. Jul 2025
  32. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.70094
  33. Jun 2025
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ESRRA (estrogen related receptor, alpha) induces ribosomal protein RPLP1-mediated adaptive hepatic translation during prolonged starvation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12087656/
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Synthesis, Structure–Activity Relationship, and Biological Evaluation of a Novel Malabaricone Derivative: A Potent Anticancer Agent and Radiosensitizer That Targets Autophagy Flux
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    pmc.ncbi.nlm.nih.gov/articles/PMC12138602/
  36. May 2025
  37. www.tandfonline.com www.tandfonline.com
    MCOLN1/TRPML1-MCOLN3/TRPML3 heteromer and its coupling to Ca2+ sensor SYT5 regulates autophagosome-lysosome fusion in a PtdIns4P-dependent manner
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    tandfonline.com/doi/abs/10.1080/15548627.2025.2510846
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Altered Mitochondrial Bioenergetics and Calcium Kinetics in Young‐Onset PLA2G6 Parkinson's Disease iPSCs
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    pmc.ncbi.nlm.nih.gov/articles/PMC11973445/
  39. Apr 2025
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A CRISPR-edited isoform of the AMPK kinase LKB1 improves the response to cisplatin in A549 lung cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11952844/
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SET8 inhibition preserves PTEN to attenuate kidney cell apoptosis in cisplatin nephrotoxicity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11958763/
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    APOE4 impairs autophagy and Aβ clearance by microglial cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11958439/
  43. Mar 2025
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modulation of Pancreatic Neuroendocrine Neoplastic Cell Fate by Autophagy-Mediated Death
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    pmc.ncbi.nlm.nih.gov/articles/PMC11905116/
  45. Jan 2025
  46. www.sciencedirect.com www.sciencedirect.com
    Ca2+/calmodulin-dependent protein kinase II β decodes ER Ca2+ transients to trigger autophagosome formation
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    sciencedirect.com/science/article/pii/S1097276524010001
  47. www.sciencedirect.com www.sciencedirect.com
    Andrographolide mitigates neurotoxicity induced by lipopolysaccharide or amyloid-β through modulation of miR-222-mediated p62 and NF-κBp65 expression
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    sciencedirect.com/science/article/pii/S0014299924009142
  48. Dec 2024
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TIGAR coordinates senescence-associated secretory phenotype via lysosome repositioning and α-tubulin deacetylation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11671532/
  50. Sep 2024
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CTCF and BORIS-mediated autophagy regulation via alternative splicing of BNIP3L in breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11254729/
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SET8 inhibition preserves PTEN to attenuate kidney cell apoptosis in cisplatin nephrotoxicity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11343278/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLC13A3 is a major effector downstream of activated β-catenin in liver cancer pathogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11364541/
  54. Aug 2024
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuronal autosis is Na+/K+-ATPase alpha 3-dependent and involved in hypoxic-ischemic neuronal death
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    ncbi.nlm.nih.gov/pmc/articles/PMC11127954/
  56. Jul 2024
  57. www.sciencedirect.com www.sciencedirect.com
    Autophagic signaling promotes systems-wide remodeling in skeletal muscle upon oncometabolic stress by D2-HG
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    sciencedirect.com/science/article/pii/S2212877824001005
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rescue of lysosomal function as therapeutic strategy for SPG15 hereditary spastic paraplegia
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    ncbi.nlm.nih.gov/pmc/articles/PMC9976989/
  59. Jun 2024
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HIV-1 Tat-Mediated Human Müller Glial Cell Senescence Involves Endoplasmic Reticulum Stress and Dysregulated Autophagy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11209317/
  61. Feb 2024
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nutrient restriction-activated Fra-2 promotes tumor progression via IGF1R in miR-15a downmodulated pancreatic ductal adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10859382/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Olanzapine, risperidone and ziprasidone differently affect lysosomal function and autophagy, reflecting their different metabolic risk in patients
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    ncbi.nlm.nih.gov/pmc/articles/PMC10774340/
  64. Dec 2023
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Quantitative Analysis of Autophagy in Single Cells: Differential Response to Amino Acid and Glucose Starvation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10705537/
  66. link.springer.com link.springer.com
    Ethanol extract of Andrographis paniculata alleviates aluminum-induced neurotoxicity and cognitive impairment through regulating the p62-keap1-Nrf2 pathway
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    link.springer.com/article/10.1186/s12906-023-04290-4
  67. Oct 2023
  68. www.sciencedirect.com www.sciencedirect.com
    ApoE4-dependent lysosomal cholesterol accumulation impairs mitochondrial homeostasis and oxidative phosphorylation in human astrocytes
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    sciencedirect.com/science/article/pii/S2211124723011956
  69. Sep 2023
  70. link.springer.com link.springer.com
    Induction of proteasomal activity in mammalian cells by lifespan-extending tRNA synthetase inhibitors
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    link.springer.com/article/10.1007/s11357-023-00938-8
  71. Jul 2023
  72. www.sciencedirect.com www.sciencedirect.com
    Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery
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    sciencedirect.com/science/article/pii/S2211124723008185
  73. Jun 2023
  74. www.sciencedirect.com www.sciencedirect.com
    SARS-CoV-2 ORF3c impairs mitochondrial respiratory metabolism, oxidative stress, and autophagic flux
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    sciencedirect.com/science/article/pii/S2589004223011951
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLIT2/ROBO1 signaling suppresses mTORC1 for organelle control and bacterial killing
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    ncbi.nlm.nih.gov/pmc/articles/PMC10264968/
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Restored autophagy is protective against PAK3-induced cardiac dysfunction
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    ncbi.nlm.nih.gov/pmc/articles/PMC10265534/
  77. May 2023
  78. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Therapeutic induction of Bcl2-associated athanogene 3-mediated autophagy in idiopathic pulmonary fibrosis
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    onlinelibrary.wiley.com/doi/10.1002/ctm2.935
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatiotemporal Patterns of Substance P-Bound MRGPRX2 Reveal a Novel Connection Between Macropinosome Resolution and Secretory Granule Regeneration in Mast Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9273857/
  80. Mar 2023
  81. www.tandfonline.com www.tandfonline.com
    Synergic induction of autophagic cell death in anaplastic thyroid carcinoma
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    tandfonline.com/doi/abs/10.1080/07357907.2023.2183027
  82. Oct 2022
  83. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The phospholipid flippase ATP8B1 is required for lysosomal fusion in macrophages
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    onlinelibrary.wiley.com/doi/10.1002/cbf.3752
  84. www.sciencedirect.com www.sciencedirect.com
    Calcium transients on the ER surface trigger liquid-liquid phase separation of FIP200 to specify autophagosome initiation sites
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    sciencedirect.com/science/article/pii/S0092867422011230
  85. www.sciencedirect.com www.sciencedirect.com
    Essential role for epithelial HIF-mediated xenophagy in control of Salmonella infection and dissemination
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    sciencedirect.com/science/article/pii/S2211124722012505
  86. Sep 2022
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Impairment of Neuronal Mitochondrial Quality Control in Prion-Induced Neurodegeneration
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    ncbi.nlm.nih.gov/pmc/articles/PMC9454542/
  88. Jul 2022
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activated Endolysosomal Cation Channel TRPML1 Facilitates Maturation of α-Synuclein-Containing Autophagosomes
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    ncbi.nlm.nih.gov/pmc/articles/PMC9296810/
  90. Mar 2022
  91. www.sciencedirect.com www.sciencedirect.com
    K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy
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    sciencedirect.com/science/article/pii/S2211124722000705
  92. Feb 2022
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tri-2-Hydroxyarachidonein Induces Cytocidal Autophagy in Pancreatic Ductal Adenocarcinoma Cancer Cell Models
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    ncbi.nlm.nih.gov/pmc/articles/PMC8811354/
  94. Jan 2022
  95. www.sciencedirect.com www.sciencedirect.com
    miR-376a-3p and miR-376b-3p overexpression in Hutchinson-Gilford progeria fibroblasts inhibits cell proliferation and induces premature senescence
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    sciencedirect.com/science/article/pii/S258900422200027X
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STAT3 Enhances Sensitivity of Glioblastoma to Drug-Induced Autophagy-Dependent Cell Death
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    ncbi.nlm.nih.gov/pmc/articles/PMC8773829/
  97. link.springer.com link.springer.com
    Approaches and Protocols to Analyze Autophagy and Its Role in Death of Apoptosis-Resistant Senescent Tumor Cells
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    link.springer.com/protocol/10.1007/978-1-0716-2071-7_10
  98. Nov 2021
  99. www.sciencedirect.com www.sciencedirect.com
    ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egress
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    sciencedirect.com/science/article/pii/S1534580721008078
  100. Oct 2021
  101. www.sciencedirect.com www.sciencedirect.com
    Humanin-induced autophagy plays important roles in skeletal muscle function and lifespan extension
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    sciencedirect.com/science/article/pii/S0304416521001768
  102. Sep 2021
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Novel Antitumor Compound HCA Promotes Glioma Cell Death by Inducing Endoplasmic Reticulum Stress and Autophagy
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    ncbi.nlm.nih.gov/pmc/articles/PMC8428344/
  104. Jun 2021
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    V600EBRAF Inhibition Induces Cytoprotective Autophagy through AMPK in Thyroid Cancer Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8199856/
  106. www.sciencedirect.com www.sciencedirect.com
    Mammalian cells use the autophagy process to restrict avian influenza virus replication
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    sciencedirect.com/science/article/pii/S2211124721005635
  107. www.nature.com www.nature.com
    The P-type ATPase transporter ATP7A promotes angiogenesis by limiting autophagic degradation of VEGFR2
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    nature.com/articles/s41467-021-23408-1
  108. May 2021
  109. www.sciencedirect.com www.sciencedirect.com
    Inositol Polyphosphate Multikinase Inhibits Liquid-Liquid Phase Separation of TFEB to Negatively Regulate Autophagy Activity
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    sciencedirect.com/science/article/pii/S1534580720308005
  110. Apr 2021
  111. www.sciencedirect.com www.sciencedirect.com
    Lipid-mediated motor-adaptor sequestration impairs axonal lysosome delivery leading to autophagic stress and dystrophy in Niemann-Pick type C
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    sciencedirect.com/science/article/pii/S1534580721003075
  112. www.nature.com www.nature.com
    The critical role of FXR is associated with the regulation of autophagy and apoptosis in the progression of AKI to CKD
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    nature.com/articles/s41419-021-03620-z
  113. Feb 2021
  114. www.sciencedirect.com www.sciencedirect.com
    ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation
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    sciencedirect.com/science/article/pii/S1534580720310169
  115. Oct 2020
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The dynamic interplay between ATP/ADP levels and autophagy sustain neuronal migration in vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC7556871/
  117. Sep 2020
  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial Ca2+ Uptake Relieves Palmitate-Induced Cytosolic Ca2+ Overload in MIN6 Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC6999716/