85 Matching Annotations
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    ER-liquid condensate contacts sequester FAM134B/C and RhoA to govern cell morphology
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    sciencedirect.com/science/article/pii/S1097276526005137
  3. Aug 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification and functional validation of EPS15L1 as a key driver of triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13434348/
  5. Jun 2026
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    IGF2BP3 is essential for the growth heterogeneity of colorectal adenoma cells by regulating MYC
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    Cuproptosis-immunity crosstalk informs strategy to overcome immunotherapy resistance
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    Structure-guided optimization of SLC1A1/EAAT3-selective inhibitors targeting renal cancer metabolism
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    Genome-wide CRISPR screen identifies a cytokine-enhancer circuit driving HIF-2α activation in renal cancer
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  10. Apr 2026
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    RHOV is a Detachment-Responsive Rho GTPase Necessary for Ovarian Cancer Peritoneal Metastasis
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    A hotspot phosphorylation site on SHP2 drives oncoprotein activation and drug resistance
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    Integrative analysis of mRNA stability regulation uncovers a metastasis-suppressive program in breast cancer
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  14. Mar 2026
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    Three-dimensional reconstruction of a biliary system in a bioengineered liver using decellularized scaffold
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    A simple method for analyzing competitive growth of multiple cell types in xenograft tumors
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  17. Feb 2026
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    Regulation of LRRK2 mRNA stability by ATIC and its substrate AICAR through ARE‐mediated mRNA decay in Parkinson's disease
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  19. Jan 2026
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    TDP‐43 and APOE: A complex interaction
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    Loss of EHMT2 enhances NK cell-driven anti-tumor immunity through TGF-β1 suppression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12808752/
  22. academic.oup.com academic.oup.com
    Androgen Receptors Promote Oxidative Phosphorylation and Resistance to Palmitate Lipotoxicity in ER-Mutant Breast Cancer
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  23. Dec 2025
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PCSK5M452I is a recessive hypomorph exclusive to MCF10DCIS.com cells
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  25. Nov 2025
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The SLC1A1/EAAT3 dicarboxylic amino acid transporter is an epigenetically dysregulated nutrient carrier that sustains oncogenic metabolic programs
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  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The lipid droplet protein DHRS3 is a regulator of melanoma cell state
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  28. Sep 2025
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    PDE7A inhibition suppresses triple-negative breast cancer by attenuating de novo pyrimidine biosynthesis
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    NNMT-driven metabolic reprogramming creates a NAMPT druggable vulnerability and reveals liquid biopsy biomarkers for TKI resistance in EGFR-mutant NSCLC
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    A Hotspot Phosphorylation Site on SHP2 Drives Oncoprotein Activation and Drug Resistance
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  32. Aug 2025
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    ER-phagy and proteostasis defects prime pancreatic epithelial state changes in KRAS-mediated oncogenesis
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    Membrane-wide screening identifies potential tissue-specific determinants of SARS-CoV-2 tropism
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    A Hotspot Phosphorylation Site on SHP2 Drives Oncoprotein Activation and Drug Resistance
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  36. Jul 2025
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  38. Jun 2025
  39. www.nature.com www.nature.com
    DMXL1 promotes recruitment of V1-ATPase to lysosomes upon TRPML1 activation
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  41. Apr 2025
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    Radiotherapy promotes cuproptosis and synergizes with cuproptosis inducers to overcome tumor radioresistance
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    PCSK5M452I is a recessive hypomorph exclusive to MCF10DCIS.com cells
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    Metabolic constraint of human telomere length by nucleotide salvage efficiency
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    VIPAS39 confers ferroptosis resistance in epithelial ovarian cancer through exporting ACSL4
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  47. Mar 2025
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    SOD2 is a regulator of proteasomal degradation promoting an adaptive cellular starvation response
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  50. Feb 2025
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    TRIP13 protects pancreatic cancer cells against intrinsic and therapy-induced DNA replication stress
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    Oncofetal reprogramming drives phenotypic plasticity in WNT-dependent colorectal cancer
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  53. Jan 2025
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    SLC7A5 is required for cancer cell growth under arginine-limited conditions
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  55. Dec 2024
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MRGPRX4 mediates phospho-drug associated pruritus in a humanized mouse model
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    Suppression of ADP-ribosylation reversal triggers cell vulnerability to alkylating agents
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  58. Sep 2024
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    PDCD10 Is a Key Player in TMZ-Resistance and Tumor Cell Regrowth: Insights into Its Underlying Mechanism in Glioblastoma Cells
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  60. Jul 2024
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    SLC7A5 is required for citrulline-dependent growth in arginine limited conditions
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    Testis-specific serine kinase 6 (TSSK6) is abnormally expressed in colorectal cancer and promotes oncogenic behaviors
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  64. Jun 2024
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    In Vivo Genome-Wide CRISPR Screening Identifies CITED2 as a Driver of Prostate Cancer Bone Metastasis
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  66. May 2024
  67. www.cell.com www.cell.com
    ALK inhibitors suppress HCC and synergize with anti-PD-1 therapy and ABT-263 in preclinical models
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  68. Apr 2024
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    Ligand-based virtual-screening identified a novel CFTR ligand which improves the defective cell surface expression of misfolded ABC transporters
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    A Novel Class of Human ADAM8 Inhibitory Antibodies for Treatment of Triple-Negative Breast Cancer
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    Lysyl Oxidase Regulates Epithelial Differentiation and Barrier Integrity in Eosinophilic Esophagitis
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    Context-dependent roles for ubiquitous mitochondrial creatine kinase CKMT1 in breast cancer progression
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  74. Mar 2024
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    Targeting Tryptophan Catabolism in Ovarian Cancer to Attenuate Macrophage Infiltration and PD-L1 Expression
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  77. Feb 2024
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    HERC3 E3 ligase provides an ERAD branch eliminating select membrane proteins
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    Combined BET and MEK Inhibition synergistically suppresses melanoma by targeting YAP1
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    c-Fos regulated by TMPO/ERK axis promotes 5-FU resistance via inducing NANOG transcription in colon cancer
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  82. Sep 2023
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    Inhibition of Abelson Tyrosine-Protein Kinase 2 Suppresses the Development of Alcohol-Associated Liver Disease by Decreasing PPARgamma Expression
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  84. Aug 2023
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    TIGIT can inhibit T cell activation via ligation-induced nanoclusters, independent of CD226 co-stimulation
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  86. Jun 2023
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    Role of Nudt2 in Anchorage-Independent Growth and Cell Migration of Human Melanoma
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    Intracellular pH dynamics regulates intestinal stem cell lineage specification
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  89. May 2023
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    Vangl-dependent Wnt/planar cell polarity signaling mediates collective breast carcinoma motility and distant metastasis
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    A Mesenchymal Tumor Cell State Confers Increased Dependency on the BCL-XL Anti-apoptotic Protein in Kidney Cancer
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  92. Mar 2023
  93. www.biorxiv.org www.biorxiv.org
    YAP signaling regulates the cellular uptake and therapeutic effect of nanoparticles
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    biorxiv.org/content/10.1101/2023.03.10.532035v1
  94. Feb 2023
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct but interchangeable subpopulations of colorectal cancer cells with different growth fates and drug sensitivity
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  96. Sep 2022
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    TGFBR3 supports anoikis through suppressing ATF4 signaling
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  98. Jun 2022
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    Supramolecular assembly of GSK3α as a cellular response to amino acid starvation
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  100. May 2022
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    The AMPK-related kinase NUAK2 suppresses glutathione peroxidase 4 expression and promotes ferroptotic cell death in breast cancer cells
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  102. Jan 2022
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    Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion
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  104. Oct 2021
  105. www.jneurosci.org www.jneurosci.org
    Metabolic control of sensory neuron survival by the p75 neurotrophin receptor in Schwann cells
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  106. Jul 2021
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    Low-Level Saturated Fatty Acid Palmitate Benefits Liver Cells by Boosting Mitochondrial Metabolism via CDK1-SIRT3-CPT2 Cascade
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  108. Jun 2021
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    Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity
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  110. May 2021
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    Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease
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    YAP1 Mediates Trametinib Resistance in Head and Neck Squamous Cell Carcinomas
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  113. Apr 2021
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    MAX Functions as a Tumor Suppressor and Rewires Metabolism in Small Cell Lung Cancer
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  115. Feb 2021
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PCK1 and DHODH drive colorectal cancer liver metastatic colonization and hypoxic growth by promoting nucleotide synthesis
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  117. www.cell.com www.cell.com
    TMEM41B IS A PAN-FLAVIVIRUS HOST FACTOR
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    cell.com/cell/abstract/S0092-8674(20)31627-5
  118. Jan 2021
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    NAD+ boosting reduces age-associated amyloidosis and restores mitochondrial homeostasis in muscle
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  120. Sep 2020
  121. www.jneurosci.org www.jneurosci.org
    Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk
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  122. Jan 2020
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    Genomic and Transcriptomic Determinants of Therapy Resistance and Immune Landscape Evolution during Anti-EGFR Treatment in Colorectal Cancer
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