42 Matching Annotations
  1. Last 7 days
  2. www.biorxiv.org www.biorxiv.org
    SLC7A5 is required for citrulline-dependent growth in arginine limited conditions
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    1. scibot 03 Jul 2024
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      DOI: 10.1101/2024.06.27.600869

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    biorxiv.org/content/10.1101/2024.06.27.600869v1
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Testis-specific serine kinase 6 (TSSK6) is abnormally expressed in colorectal cancer and promotes oncogenic behaviors
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11214309/
  4. Jun 2024
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In Vivo Genome-Wide CRISPR Screening Identifies CITED2 as a Driver of Prostate Cancer Bone Metastasis
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    1. scibot 21 Jun 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11101692/
  6. May 2024
  7. www.cell.com www.cell.com
    ALK inhibitors suppress HCC and synergize with anti-PD-1 therapy and ABT-263 in preclinical models
    1
    1. scibot 10 May 2024
      RRID:Addgene_25890

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    cell.com/iscience/abstract/S2589-0042(24)01022-8
  8. Apr 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ligand-based virtual-screening identified a novel CFTR ligand which improves the defective cell surface expression of misfolded ABC transporters
    1
    1. scibot 30 Apr 2024
      25890

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    ncbi.nlm.nih.gov/pmc/articles/PMC11043560/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel Class of Human ADAM8 Inhibitory Antibodies for Treatment of Triple-Negative Breast Cancer
    1
    1. scibot 29 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11054802/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lysyl Oxidase Regulates Epithelial Differentiation and Barrier Integrity in Eosinophilic Esophagitis
    1
    1. scibot 23 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11026689/
  12. aacrjournals.org aacrjournals.org
    Adipose triglyceride lipase is a therapeutic target in advanced prostate cancer that promotes metabolic plasticity
    1
    1. scibot 19 Apr 2024
      RRID:Addgene_25890

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    aacrjournals.org/cancerres/article/84/5/703/734936/Adipose-Triglyceride-Lipase-Is-a-Therapeutic
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context-dependent roles for ubiquitous mitochondrial creatine kinase CKMT1 in breast cancer progression
    1
    1. scibot 19 Apr 2024
      RRID:Addgene_25890

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    ncbi.nlm.nih.gov/pmc/articles/PMC11100297/
  14. Mar 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting Tryptophan Catabolism in Ovarian Cancer to Attenuate Macrophage Infiltration and PD-L1 Expression
    1
    1. scibot 20 Mar 2024
      RRID:Addgene_25890

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    ncbi.nlm.nih.gov/pmc/articles/PMC10946310/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An engineered biosensor enables dynamic aspartate measurements in living cells
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    1. scibot 17 Mar 2024
      25890

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    ncbi.nlm.nih.gov/pmc/articles/PMC10942590/
  17. Feb 2024
  18. 52.53.155.43 52.53.155.43
    HERC3 E3 ligase provides an ERAD branch eliminating select membrane proteins
    1
    1. scibot 23 Feb 2024
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    52.53.155.43/893a986f25098b75e101f0b7cb970068940c81b3/2023.10.16.562477v2.full-html.html
  19. 52.53.155.43 52.53.155.43
    can-23-0555-html.html
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    1. scibot 23 Feb 2024
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      RRID:Addgene_25890

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    52.53.155.43/e8db3efafb8a8253e8641e16f59e9a4a6a668dad/can-23-0555-html.html
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined BET and MEK Inhibition synergistically suppresses melanoma by targeting YAP1
    1
    1. scibot 13 Feb 2024
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      DOI: 10.7150/thno.85437

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    ncbi.nlm.nih.gov/pmc/articles/PMC10758063/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    c-Fos regulated by TMPO/ERK axis promotes 5-FU resistance via inducing NANOG transcription in colon cancer
    1
    1. scibot 01 Feb 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10794174/
  22. Sep 2023
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of Abelson Tyrosine-Protein Kinase 2 Suppresses the Development of Alcohol-Associated Liver Disease by Decreasing PPARgamma Expression
    2
    1. scibot 29 Sep 2023
      RRID:Addgene_25890

      DOI: 10.1016/j.jcmgh.2023.07.006

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    ncbi.nlm.nih.gov/pmc/articles/PMC10520367/
  24. Aug 2023
  25. www.nature.com www.nature.com
    TIGIT can inhibit T cell activation via ligation-induced nanoclusters, independent of CD226 co-stimulation
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    1. scibot 24 Aug 2023
      Plasmid_25890

      DOI: 10.1038/s41467-023-40755-3

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    nature.com/articles/s41467-023-40755-3
  26. Jun 2023
  27. www.mdpi.com www.mdpi.com
    Role of Nudt2 in Anchorage-Independent Growth and Cell Migration of Human Melanoma
    1
    1. scibot 27 Jun 2023
      RRID:Addgene_25890

      DOI: 10.3390/ijms241310513

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    mdpi.com/1422-0067/24/13/10513
  28. www.nature.com www.nature.com
    Intracellular pH dynamics regulates intestinal stem cell lineage specification
    1
    1. scibot 24 Jun 2023
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    nature.com/articles/s41467-023-39312-9
  29. May 2023
  30. link.springer.com link.springer.com
    Vangl-dependent Wnt/planar cell polarity signaling mediates collective breast carcinoma motility and distant metastasis
    1
    1. scibot 06 May 2023
      RRID:Addgene_25890

      DOI: 10.1186/s13058-023-01651-2

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    link.springer.com/article/10.1186/s13058-023-01651-2
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Mesenchymal Tumor Cell State Confers Increased Dependency on the BCL-XL Anti-apoptotic Protein in Kidney Cancer
    1
    1. scibot 04 May 2023
      RRID:Addgene_25890

      DOI: 10.1158/1078-0432.CCR-22-0669

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    ncbi.nlm.nih.gov/pmc/articles/PMC9633392/
  32. Mar 2023
  33. www.biorxiv.org www.biorxiv.org
    YAP signaling regulates the cellular uptake and therapeutic effect of nanoparticles
    1
    1. scibot 16 Mar 2023
      RRID:Addgene_25890

      DOI: 10.1101/2023.03.10.532035

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    biorxiv.org/content/10.1101/2023.03.10.532035v1
  34. Feb 2023
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct but interchangeable subpopulations of colorectal cancer cells with different growth fates and drug sensitivity
    1
    1. scibot 01 Feb 2023
      Addgene_25890

      DOI: 10.1016/j.isci.2023.105962

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    ncbi.nlm.nih.gov/pmc/articles/PMC9883198/
  36. Sep 2022
  37. journals.biologists.com journals.biologists.com
    TGFBR3 supports anoikis through suppressing ATF4 signaling
    1
    1. scibot 22 Sep 2022
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      DOI: 10.1242/jcs.258396

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    journals.biologists.com/jcs/article/135/17/jcs258396/276460/TGFBR3-supports-anoikis-through-suppressing-ATF4
  38. Jun 2022
  39. www.sciencedirect.com www.sciencedirect.com
    Supramolecular assembly of GSK3α as a cellular response to amino acid starvation
    1
    1. scibot 22 Jun 2022
      plasmid_25890

      DOI: 10.1016/j.molcel.2022.05.025

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    sciencedirect.com/science/article/pii/S1097276522004920
  40. May 2022
  41. www.nature.com www.nature.com
    The AMPK-related kinase NUAK2 suppresses glutathione peroxidase 4 expression and promotes ferroptotic cell death in breast cancer cells
    1
    1. scibot 10 May 2022
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      DOI: 10.1038/s41420-022-01044-y

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    nature.com/articles/s41420-022-01044-y
  42. Jan 2022
  43. www.sciencedirect.com www.sciencedirect.com
    Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion
    1
    1. scibot 26 Jan 2022
      RRID:Addgene_25890

      DOI: 10.1016/j.celrep.2021.110227

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    sciencedirect.com/science/article/pii/S2211124721017319
  44. Oct 2021
  45. www.jneurosci.org www.jneurosci.org
    Metabolic control of sensory neuron survival by the p75 neurotrophin receptor in Schwann cells
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    1. scibot 27 Oct 2021
      Addgene_25890

      DOI: 10.1523/JNEUROSCI.3243-20.2021

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    jneurosci.org/content/41/42/8710
  46. Jul 2021
  47. www.sciencedirect.com www.sciencedirect.com
    Low-Level Saturated Fatty Acid Palmitate Benefits Liver Cells by Boosting Mitochondrial Metabolism via CDK1-SIRT3-CPT2 Cascade
    1
    1. scibot 30 Jul 2021
      RRID: Addgene_25890

      DOI: 10.1016/j.devcel.2019.11.012

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    sciencedirect.com/science/article/pii/S1534580719309438
  48. Jun 2021
  49. www.sciencedirect.com www.sciencedirect.com
    Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity
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    sciencedirect.com/science/article/pii/S1535610821002841
  50. May 2021
  51. www.sciencedirect.com www.sciencedirect.com
    Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease
    2
    1. scibot 21 May 2021
      Cat# 25890

      DOI: 10.1016/j.molcel.2021.04.028

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    sciencedirect.com/science/article/pii/S1097276521003579
  52. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    YAP1 Mediates Trametinib Resistance in Head and Neck Squamous Cell Carcinomas
    1
    1. scibot 10 May 2021
      RRID:Addgene_25890

      DOI: 10.1158/1078-0432.CCR-19-4179

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    clincancerres.aacrjournals.org/content/27/8/2326
  53. Apr 2021
  54. www.sciencedirect.com www.sciencedirect.com
    MAX Functions as a Tumor Suppressor and Rewires Metabolism in Small Cell Lung Cancer
    1
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      Cat# 25890

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    sciencedirect.com/science/article/pii/S1535610820302154
  55. Feb 2021
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PCK1 and DHODH drive colorectal cancer liver metastatic colonization and hypoxic growth by promoting nucleotide synthesis
    1
    1. scibot 25 Feb 2021
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      DOI: 10.7554/eLife.52135

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    ncbi.nlm.nih.gov/pmc/articles/PMC7299340/
  57. www.cell.com www.cell.com
    TMEM41B IS A PAN-FLAVIVIRUS HOST FACTOR
    1
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      RRID:Addgene_25890

      DOI: 10.1016/j.cell.2020.12.005

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    cell.com/cell/abstract/S0092-8674(20)31627-5
  58. Jan 2021
  59. www.sciencedirect.com www.sciencedirect.com
    NAD+ boosting reduces age-associated amyloidosis and restores mitochondrial homeostasis in muscle
    1
    1. scibot 20 Jan 2021
      Plasmid_25890

      DOI: 10.1016/j.celrep.2020.108660

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    sciencedirect.com/science/article/pii/S2211124720316491
  60. Sep 2020
  61. www.jneurosci.org www.jneurosci.org
    Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk
    1
    1. scibot 26 Sep 2020
      plasmid_25890

      DOI: 10.1523/JNEUROSCI.2994-18.2019

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    jneurosci.org/content/39/37/7408
  62. Jan 2020
  63. www.sciencedirect.com www.sciencedirect.com
    Genomic and Transcriptomic Determinants of Therapy Resistance and Immune Landscape Evolution during Anti-EGFR Treatment in Colorectal Cancer
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_25890

      DOI: 10.1016/j.ccell.2019.05.013

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    sciencedirect.com/science/article/pii/S1535610819302557