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Caspase-5c amplifies Wnt via APC cleavage to promote intestinal homeostasis

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1. scibot 19 Aug 2026
  
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  plasmid_26429
  
  DOI: 10.1038/s41586-026-10343-8
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13476857/
Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Vitamin B2 metabolism promotes FSP1 stability to prevent ferroptosis

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1. scibot 27 Mar 2026
  
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  26429
  
  DOI: 10.1038/s41594-026-01759-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12999485/
Feb 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Precise control of transcription condensates across S phase balances linker histone expression with DNA replication, ensuring genome stability

1
1. scibot 05 Feb 2026
  
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  AddgeneCat# 26429
  
  DOI: 10.1016/j.molcel.2026.01.005
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12995521/
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Circadian circuits control plasticity of group 3 innate lymphoid cells by sustaining epigenetic configuration of RORγt

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1. scibot 23 Nov 2025
  
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  Plasmid_26429
  
  DOI: 10.1038/s41590-025-02240-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12633719/
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Lysosomal Protease-Mediated APP Degradation is pH-Dependent, Mutation-Sensitive, and Facilitates Tau Proteolysis

1
1. scibot 11 Aug 2025
  
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  Addgene_26429
  
  DOI: 10.21203/rs.3.rs-6978813/v1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12265180/
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Integrated in vivo functional screens and multiomics analyses identify α-2,3-sialylation as essential for melanoma maintenance

1
1. scibot 20 Jul 2025
  
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  26429
  
  DOI: 10.1126/sciadv.adg3481
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12227053/
Mar 2025
www.sciencedirect.com www.sciencedirect.com

Three-dimensional regulatory hubs support oncogenic programs in glioblastoma

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1. scibot 28 Mar 2025
  
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  Addgene_26429
  
  DOI: 10.1016/j.molcel.2025.03.007
  
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sciencedirect.com/science/article/pii/S109727652500200X
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Combinational Inhibition of MEK and AKT Synergistically Induces Melanoma Stem Cell Apoptosis and Blocks NRAS Tumor Growth

1
1. scibot 11 Mar 2025
  
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  pLenti-CMV-rtTA3 Blast
  
  DOI: 10.3390/cells14040248
  
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  Curator: @olekpark
  
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  DOI:10.3390/cells14040248 RRID:Addgene_26429
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pmc.ncbi.nlm.nih.gov/articles/PMC11852824/
Aug 2024
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<em>Neuropathology and Applied Neurobiology</em> | BNS Journal | Wiley Online Library

1
1. scibot 19 Aug 2024
  
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  Plasmid_26429
  
  DOI: 10.1111/nan.12991
  
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onlinelibrary.wiley.com/doi/10.1111/nan.12991
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Serine/arginine-rich splicing factor 7 promotes the type I interferon response by activating Irf7 transcription

1
1. scibot 13 Aug 2024
  
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  pLenti CMV rtTA3 Blast
  
  DOI: 10.1016/j.celrep.2024.113816
  
  Resource: RRID:Addgene_26429
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11056844/
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CD133 Stimulates Cell Proliferation via the Upregulation of Amphiregulin in Melanoma

1
1. scibot 12 May 2024
  
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  pLenti-CMV-rtTA3 Blast
  
  DOI: 10.3390/cells13090777
  
  Resource: RRID:Addgene_26429
  
  Curator: @olekpark
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11083289/
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Integrated in vivo functional screens and multi-omics analyses identify α-2,3-sialylation as essential for melanoma maintenance

1
1. scibot 15 Apr 2024
  
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  Addgene_26429
  
  DOI: 10.1101/2024.03.08.584072
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10979837/
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Hypoxia-induced immortalization of primary cells depends on Tfcp2L1 expression

1
1. scibot 17 Mar 2024
  
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  26429
  
  DOI: 10.1038/s41419-024-06567-z
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10902313/
Dec 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality

1
1. scibot 20 Dec 2023
  
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  RRID:Addgene_26429
  
  DOI: 10.1158/0008-5472.CAN-22-2948
  
  Resource: RRID:Addgene_26429
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10722143/
Apr 2023
www.nature.com www.nature.com

Disease-related p63 DBD mutations impair DNA binding by distinct mechanisms and varying degree

1
1. scibot 20 Apr 2023
  
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  plasmid_26429
  
  DOI: 10.1038/s41419-023-05796-y
  
  Resource: RRID:Addgene_26429
  
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nature.com/articles/s41419-023-05796-y
Mar 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Aberrant induction of a mesenchymal/stem-cell program engages senescence in normal mammary epithelial cells.

1
1. scibot 04 Mar 2022
  
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  plasmid_26429
  
  DOI: 10.1158/1541-7786.MCR-19-1181
  
  Resource: RRID:Addgene_26429
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8867383/
Nov 2021
www.sciencedirect.com www.sciencedirect.com

LARP7 ameliorates cellular senescence and aging by allosterically enhancing SIRT1 deacetylase activity

1
1. scibot 24 Nov 2021
  
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  RRID:Addgene_26429
  
  DOI: 10.1016/j.celrep.2021.110038
  
  Resource: RRID:Addgene_26429
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124721015205
Jun 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PML Differentially Regulates Growth and Invasion in Brain Cancer

1
1. scibot 29 Jun 2021
  
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  RRID:Addgene_26429
  
  DOI: 10.3390/ijms22126289
  
  Resource: RRID:Addgene_26429
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8230868/
May 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

MAEA is an E3 ubiquitin ligase promoting autophagy and maintenance of haematopoietic stem cells

1
1. scibot 13 May 2021
  
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  RRID:Addgene_26429
  
  DOI: 10.1038/s41467-021-22749-1
  
  Resource: RRID:Addgene_26429
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8097058/
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p53 mediates target gene association with nuclear speckles for amplified RNA expression

1
1. scibot 11 May 2021
  
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  RRID:Addgene_26429
  
  DOI: 10.1016/j.molcel.2021.03.006
  
  Resource: RRID:Addgene_26429
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S109727652100174X
www.sciencedirect.com www.sciencedirect.com

Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer

1
1. scibot 09 May 2021
  
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  RRID:Addgene_26429
  
  DOI: 10.1016/j.stem.2020.07.003
  
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  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1934590920303416
Sep 2020
academic.oup.com academic.oup.com

Full length RTEL1 is required for the elongation of the single-stranded telomeric overhang by telomerase

1
1. scibot 25 Sep 2020
  
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  RRID:Addgene_26429
  
  DOI: 10.1093/nar/gkaa503
  
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  Curator: @Naa003
  
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  RRID:Addgene_26429 RRIDCUR:Validated
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academic.oup.com/nar/advance-article/doi/10.1093/nar/gkaa503/5857711
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

BRD4 Prevents R-Loop Formation and Transcription-Replication Conflicts by Ensuring Efficient Transcription Elongation

1
1. scibot 25 Sep 2020
  
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  RRID:Addgene_26429
  
  DOI: 10.1016/j.celrep.2020.108166
  
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  Curator: @Naa003
  
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  RRID:Addgene_26429 RRIDCUR:Validated
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pubmed.ncbi.nlm.nih.gov/32966794/
www.nature.com www.nature.com

Exploiting natural chemical photosensitivity of anhydrotetracycline and tetracycline for dynamic and setpoint chemo-optogenetic control

1
1. scibot 11 Sep 2020
  
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  RRID:Addgene_26429
  
  DOI: 10.1038/s41467-020-17677-5
  
  Resource: RRID:Addgene_26429
  
  Curator: @evieth
  
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  RRIDCUR:Validated RRID:Addgene_26429
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nature.com/articles/s41467-020-17677-5
www.sciencedirect.com www.sciencedirect.com

Kinetic Heterogeneity of Cancer Cell Fractional Killing

1
1. scibot 03 Sep 2020
  
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  pLenti CMV rtTA Blast (w756-1)
  
  DOI: 10.1016/j.celrep.2020.107845
  
  Resource: RRID:Addgene_26429
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_26429
  
  Curator comments: pLenti CMV rtTA3 Blast (w756-1)
  
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  RRID:Addgene_26429 RRIDCUR:Missing
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RRID:Addgene_26429

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sciencedirect.com/science/article/pii/S2211124720308263