27 Matching Annotations
  1. Apr 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Somatic mutations in four novel genes contribute to homologous recombination deficiency in breast cancer: a real‐world clinical tumor sequencing study
    1
    1. scibot 15 Apr 2024
      26475

      DOI: 10.1002/2056-4538.12367

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    ncbi.nlm.nih.gov/pmc/articles/PMC10951049/
  3. Mar 2024
  4. www.nature.com www.nature.com
    CDK9-55 guides the anaphase-promoting complex/cyclosome (APC/C) in choosing the DNA repair pathway choice
    1
    1. scibot 14 Mar 2024
      RRID:Addgene_26475

      DOI: 10.1038/s41388-024-02982-w

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    nature.com/articles/s41388-024-02982-w
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRMT5-mediated homologous recombination repair is essential to maintain genomic integrity of neural progenitor cells
    1
    1. scibot 12 Mar 2024
      RRID:Addgene_26475

      DOI: 10.1007/s00018-024-05154-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC10923982/
  6. Jan 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Tolerance to colibactin correlates with homologous recombination proficiency and resistance to irinotecan in colorectal cancer cells
    1
    1. scibot 19 Jan 2024
      RRID:Addgene_26475

      DOI: 10.1016/j.xcrm.2023.101376

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    sciencedirect.com/science/article/pii/S2666379123006055
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FAK Drives Resistance to Therapy in HPV-Negative Head and Neck Cancer in a p53-Dependent Manner
    1
    1. scibot 10 Jan 2024
      RRID:Addgene_26475

      DOI: 10.1158/1078-0432.CCR-23-0964

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    ncbi.nlm.nih.gov/pmc/articles/PMC10767302/
  9. Dec 2023
  10. link.springer.com link.springer.com
    PRAME induces genomic instability in uveal melanoma
    1
    1. scibot 02 Dec 2023
      plasmid_26475

      DOI: 10.1038/s41388-023-02887-0

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    link.springer.com/article/10.1038/s41388-023-02887-0
  11. Nov 2023
  12. www.nature.com www.nature.com
    Repression of LSD1 potentiates homologous recombination-proficient ovarian cancer to PARP inhibitors through down-regulation of BRCA1/2 and RAD51
    2
    1. scibot 25 Nov 2023
      plasmid_26475

      DOI: 10.1038/s41467-023-42850-x

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    2. scibot 25 Nov 2023
      plasmid_26475

      DOI: 10.1038/s41467-023-42850-x

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    nature.com/articles/s41467-023-42850-x
  13. Oct 2023
  14. www.sciencedirect.com www.sciencedirect.com
    Tyrosine catabolism enhances genotoxic chemotherapy by suppressing translesion DNA synthesis in epithelial ovarian cancer
    1
    1. scibot 28 Oct 2023
      Plasmid_26475

      DOI: 10.1016/j.cmet.2023.10.002

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    sciencedirect.com/science/article/pii/S1550413123003716
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting MALAT1 Augments Sensitivity to PARP Inhibition by Impairing Homologous Recombination in Prostate Cancer
    1
    1. scibot 12 Oct 2023
      RRID:Addgene_26475

      DOI: 10.1158/2767-9764.CRC-23-0089

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    ncbi.nlm.nih.gov/pmc/articles/PMC10561629/
  16. Sep 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TLK1-mediated RAD54 phosphorylation spatio-temporally regulates Homologous Recombination Repair
    1
    1. scibot 17 Sep 2023
      RRID:Addgene_26475

      DOI: 10.1093/nar/gkad589

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    ncbi.nlm.nih.gov/pmc/articles/PMC10484734/
  18. Jul 2023
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The hydrophilic extract from a new tomato genotype (named DHO) kills cancer cell lines through the modulation of the DNA damage response induced by Campthotecin treatment
    1
    1. scibot 06 Jul 2023
      plasmid_26475

      DOI: 10.3389/fonc.2023.1117262

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    ncbi.nlm.nih.gov/pmc/articles/PMC10318356/
  20. May 2023
  21. www.mdpi.com www.mdpi.com
    Global Genome Demethylation Causes Transcription-Associated DNA Double Strand Breaks in HPV-Associated Head and Neck Cancer Cells
    1
    1. scibot 05 May 2023
      plasmid_26

      DOI: 10.3390/cancers13010021

      Resource: RRID:Addgene_26475

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_26475

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      RRIDCUR:SyntaxError RRIDCUR:Unresolved RRID:Addgene_26475
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    mdpi.com/2072-6694/13/1/21
  22. Apr 2023
  23. link.springer.com link.springer.com
    SARS-CoV-2 viral protein Nsp2 stimulates translation under normal and hypoxic conditions
    1
    1. scibot 01 Apr 2023
      RRID:Addgene_26475

      DOI: 10.1186/s12985-023-02021-2

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    link.springer.com/article/10.1186/s12985-023-02021-2
  24. Aug 2022
  25. link.springer.com link.springer.com
    BTApep-TAT peptide inhibits ADP-ribosylation of BORIS to induce DNA damage in cancer
    1
    1. scibot 03 Aug 2022
      RRID:Addgene_26475

      DOI: 10.1186/s12943-022-01621-w

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    link.springer.com/article/10.1186/s12943-022-01621-w
  26. May 2022
  27. www.sciencedirect.com www.sciencedirect.com
    A PARylation-phosphorylation cascade promotes TOPBP1 loading and RPA-RAD51 exchange in homologous recombination
    1
    1. scibot 25 May 2022
      addgene plasmid Cat#26475

      DOI: 10.1016/j.molcel.2022.04.031

      Resource: RRID:Addgene_26475

      Curator: @sophiastull

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    sciencedirect.com/science/article/pii/S109727652200394X
  28. Apr 2022
  29. aacrjournals.org aacrjournals.org
    Loss of Claudin-4 Reduces DNA Damage Repair and Increases Sensitivity to PARP Inhibitors
    1
    1. scibot 09 Apr 2022
      RRID:Addgene_26475

      DOI: 10.1158/1535-7163.MCT-21-0827

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      Curator: @evieth

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    aacrjournals.org/mct/article/21/4/647/689566/Loss-of-Claudin-4-Reduces-DNA-Damage-Repair-and
  30. Aug 2021
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Depletion of the RNA binding protein HNRNPD impairs homologous recombination by inhibiting DNA-end resection and inducing R-loop accumulation
    1
    1. scibot 14 Aug 2021
      plasmid_26475

      DOI: 10.1093/nar/gkz076

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    ncbi.nlm.nih.gov/pmc/articles/PMC6486545/
  32. cancerres.aacrjournals.org cancerres.aacrjournals.org
    SHP2-Mediated Inhibition of DNA Repair Contributes to cGAS–STING Activation and Chemotherapeutic Sensitivity in Colon Cancer
    1
    1. scibot 12 Aug 2021
      RRID: Addgene_26475

      DOI: 10.1158/0008-5472.CAN-20-3738

      Resource: RRID:Addgene_26475

      Curator: @evieth

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    cancerres.aacrjournals.org/content/81/12/3215
  33. Jul 2021
  34. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Human RECQL4 represses the RAD52‐mediated single‐strand annealing pathway after ionizing radiation or cisplatin treatment
    1
    1. scibot 29 Jul 2021
      Addgene_26475

      DOI: 10.1002/ijc.32670

      Resource: RRID:Addgene_26475

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_26475

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      RRID:Addgene_26475 RRIDCUR:Unrecognized
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.32670
  35. May 2021
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting HR Repair as a Synthetic Lethal Approach to Increase DNA Damage Sensitivity by a RAD52 Inhibitor in BRCA2-Deficient Cancer Cells
    1
    1. scibot 19 May 2021
      RRID:Addgene_26475

      DOI: 10.3390/ijms22094422

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    ncbi.nlm.nih.gov/pmc/articles/PMC8122931/
  37. Dec 2020
  38. www.mdpi.com www.mdpi.com
    Global Genome Demethylation Causes Transcription-Associated DNA Double Strand Breaks in HPV-Associated Head and Neck Cancer Cells
    1
    1. scibot 30 Dec 2020
      RRID:Addgene_26475

      DOI: 10.3390/cancers13010021

      Resource: RRID:Addgene_26475

      Curator: @Naa003

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      RRID:Addgene_26475 RRIDCUR:Validated
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    mdpi.com/2072-6694/13/1/21
  39. Oct 2020
  40. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment
    1
    1. scibot 08 Oct 2020
      RRID:Addgene_26475

      DOI: 10.1016/j.celrep.2020.108221

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      Curator: @Naa003

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      RRIDCUR:Validated RRID:Addgene_26475
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    pubmed.ncbi.nlm.nih.gov/33027668/
  41. Sep 2020
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergy between SIRT1 and SIRT6 helps recognize DNA breaks and potentiates the DNA damage response and repair in humans and mice
    1
    1. scibot 26 Sep 2020
      RRID:Addgene_26475

      DOI: 10.7554/eLife.55828

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      Curator: @evieth

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      RRIDCUR:Validated RRID:Addgene_26475
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    ncbi.nlm.nih.gov/pmc/articles/PMC7324161/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FOXL2 directs DNA double-strand break repair pathways by differentially interacting with Ku
    1
    1. scibot 23 Sep 2020
      RRID:Addgene_26475

      DOI: 10.1038/s41467-020-15748-1

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      Curator: @evieth

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      RRIDCUR:Validated RRID:Addgene_26475
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    ncbi.nlm.nih.gov/pmc/articles/PMC7181608/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RB1 Deletion in Retinoblastoma Protein Pathway-Disrupted Cells Results in DNA Damage and Cancer Progression
    1
    1. scibot 03 Sep 2020
      Addgene_26475

      DOI: 10.1128/MCB.00105-19

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      Curator: @bandrow

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    ncbi.nlm.nih.gov/pmc/articles/PMC6664603/
  45. Jan 2020
  46. academic.oup.com academic.oup.com
    Untitled document
    1
    1. scibot 12 Jan 2020
      plasmid_26475

      DOI: 10.1093/nar/gkz076

      Resource: RRID:Addgene_26475

      Curator: @evieth

      SciCrunch record: plasmid_26475

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      RRID:Addgene_26475 RRIDCUR:Validated
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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkz076/5364135