Hypothesis

33 Matching Annotations

Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

ATR promotes mTORC1 activity via de novo cholesterol synthesis

1
1. scibot 11 Aug 2025
  
  in Public
  
  30323
  
  DOI: 10.1038/s44319-025-00451-3
  
  Resource: RRID:Addgene_30323
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12287318/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

SGK1 repression by WT1 may confer a survival advantage to leukemic cells under stress conditions

1
1. scibot 11 Aug 2025
  
  in Public
  
  30323
  
  DOI: 10.1007/s00277-025-06458-z
  
  Resource: RRID:Addgene_30323
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12334445/
www.nature.com www.nature.com

The CIC::DUX4 oncoprotein maintains DNA integrity through direct regulation of the catalytic subunit of DNA polymerase epsilon (POLE)

1
1. scibot 08 Aug 2025
  
  in Public
  
  RRID:Addgene_30323
  
  DOI: 10.1038/s41388-025-03507-9
  
  Resource: RRID:Addgene_30323
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

nature.com/articles/s41388-025-03507-9
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

VIRMA-mediated m6A modification regulates forebrain formation through modulating ribosome biogenesis

1
1. scibot 20 Jul 2025
  
  in Public
  
  30323
  
  DOI: 10.1126/sciadv.adq9643
  
  Resource: RRID:Addgene_30323
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12204135/
www.science.org www.science.org

VIRMA-mediated m6A modification regulates forebrain formation through modulating ribosome biogenesis

1
1. scibot 11 Jul 2025
  
  in Public
  
  Addgene plasmid no. 30323
  
  DOI: 10.1126/sciadv.adq9643
  
  Resource: RRID:Addgene_30323
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

science.org/doi/10.1126/sciadv.adq9643
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The retinoblastoma protein contributes to maintaining the stability of HPV E7 in cervical cancer cells

1
1. scibot 20 May 2025
  
  in Public
  
  plasmid_30323
  
  DOI: 10.1128/jvi.02203-24
  
  Resource: RRID:Addgene_30323
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11998531/
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

HCMV infection downregulates GPX4 and stimulates lipid peroxidation but does not induce ferroptosis

1
1. scibot 11 Mar 2025
  
  in Public
  
  30323
  
  DOI: 10.1128/jvi.01851-24
  
  Resource: RRID:Addgene_30323
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11852782/
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Development of Liver-Targeting αVβ5+ Exosomes as Anti-TGF-β Nanocarriers for the Treatment of the Pre-Metastatic Niche

1
1. scibot 29 Dec 2024
  
  in Public
  
  plasmid_30323
  
  DOI: 10.3390/biology13121066
  
  Resource: RRID:Addgene_30323
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11673512/
Sep 2024
www.sciencedirect.com www.sciencedirect.com

Interleukin-34-orchestrated tumor-associated macrophage reprogramming is required for tumor immune escape driven by p53 inactivation

1
1. scibot 25 Sep 2024
  
  in Public
  
  Cat# 30323
  
  DOI: 10.1016/j.immuni.2024.08.015
  
  Resource: RRID:Addgene_30323
  
  Curator: @vtello
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761324004151
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Circular RNA HMGCS1 sponges MIR4521 to aggravate type 2 diabetes-induced vascular endothelial dysfunction

1
1. scibot 12 Sep 2024
  
  in Public
  
  RRID:Addgene_30323
  
  DOI: 10.7554/eLife.97267
  
  Resource: RRID:Addgene_30323
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11377038/
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cadherin-11 contributes to the heterogenous and dynamic Wnt-Wnt-β-catenin pathway activation in Ewing sarcoma

1
1. scibot 20 Jun 2024
  
  in Public
  
  plasmid_30323
  
  DOI: 10.1371/journal.pone.0305490
  
  Resource: RRID:Addgene_30323
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11178195/
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

De Novo Purine Metabolism is a Metabolic Vulnerability of Cancers with Low p16 Expression

1
1. scibot 05 May 2024
  
  in Public
  
  Addgene_30323
  
  DOI: 10.1158/2767-9764.CRC-23-0450
  
  Resource: RRID:Addgene_30323
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11064835/
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression

1
1. scibot 24 Apr 2024
  
  in Public
  
  RRID:Addgene_30323
  
  DOI: 10.1093/narcan/zcae018
  
  Resource: RRID:Addgene_30323
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11034028/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Oligomerization mediated by the D2 domain of DTX3L is critical for DTX3L‐PARP9 reading function of mono‐ADP‐ribosylated androgen receptor

1
1. scibot 15 Apr 2024
  
  in Public
  
  Addgene_30323
  
  DOI: 10.1002/pro.4945
  
  Resource: RRID:Addgene_30323
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10955461/
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A common cellular response to broad splicing perturbations is characterized by metabolic transcript downregulation driven by the Mdm2–p53 axis

1
1. scibot 17 Mar 2024
  
  in Public
  
  30323
  
  DOI: 10.1242/dmm.050356
  
  Resource: RRID:Addgene_30323
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10924232/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

αKG-mediated carnitine synthesis promotes homologous recombination via histone acetylation

1
1. scibot 29 Feb 2024
  
  in Public
  
  30323
  
  DOI: 10.1101/2024.02.06.578742
  
  Resource: RRID:Addgene_30323
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10871207/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PKCμ promotes keratinocyte cell migration through Cx43 phosphorylation-mediated suppression of intercellular communication

1
1. scibot 23 Feb 2024
  
  in Public
  
  AddgenePlasmid #: 30323
  
  DOI: 10.1016/j.isci.2024.109033
  
  Resource: RRID:Addgene_30323
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10875573/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SP3-induced Timeless transcription contributes to cell growth of lung adenocarcinoma cells

1
1. scibot 21 Feb 2024
  
  in Public
  
  30323
  
  DOI: 10.1371/journal.pone.0298295
  
  Resource: RRID:Addgene_30323
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10866488/
www.biorxiv.org www.biorxiv.org

HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance

3
1. scibot 09 Feb 2024
  
  in Public
  
  RRID:Addgene_30323
  
  DOI: 10.1101/2023.12.05.570182
  
  Resource: RRID:Addgene_30323
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
2. scibot 09 Feb 2024
  
  in Public
  
  RRID:Addgene_30323
  
  DOI: 10.1101/2023.12.05.570182
  
  Resource: RRID:Addgene_30323
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
3. scibot 09 Feb 2024
  
  in Public
  
  RRID:Addgene_30323
  
  DOI: 10.1101/2023.12.05.570182
  
  Resource: RRID:Addgene_30323
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

biorxiv.org/content/10.1101/2023.12.05.570182v1
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Inhibiting the m6A Reader IGF2BP3 Suppresses Ovarian Cancer Cell Growth via Regulating PLAGL2 mRNA Stabilization

1
1. scibot 28 Jan 2024
  
  in Public
  
  Plasmid 30323
  
  DOI: 10.14740/wjon1747
  
  Resource: RRID:Addgene_30323
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10807918/
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mechanistic target of rapamycin (mTOR) regulates self-sustained quiescence, tumor indolence, and late clinical metastasis in a Beclin-1-dependent manner

2
1. scibot 22 Sep 2023
  
  in Public
  
  RRID:Addgene_30323
  
  DOI: 10.1080/15384101.2022.2123187
  
  Resource: RRID:Addgene_30323
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
2. scibot 22 Sep 2023
  
  in Public
  
  plasmid_30
  
  DOI: 10.1080/15384101.2022.2123187
  
  Resource: RRID:Addgene_30323
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRIDCUR:Unresolved RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

RRIDCUR:Unresolved

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9928463/
Mar 2023
www.sciencedirect.com www.sciencedirect.com

Tcf21 marks visceral adipose mesenchymal progenitors and functions as a rate-limiting factor during visceral adipose tissue development

1
1. scibot 02 Mar 2023
  
  in Public
  
  RRID:Addgene_30323
  
  DOI: 10.1016/j.celrep.2023.112166
  
  Resource: RRID:Addgene_30323
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723001778
Sep 2022
journals.biologists.com journals.biologists.com

TGFBR3 supports anoikis through suppressing ATF4 signaling

1
1. scibot 22 Sep 2022
  
  in Public
  
  Addgene_30323
  
  DOI: 10.1242/jcs.258396
  
  Resource: RRID:Addgene_30323
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

journals.biologists.com/jcs/article/135/17/jcs258396/276460/TGFBR3-supports-anoikis-through-suppressing-ATF4
Jan 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SIPA1 Enhances Aerobic Glycolysis Through HIF-2α Pathway to Promote Breast Cancer Metastasis

1
1. scibot 28 Jan 2022
  
  in Public
  
  RRID:Addgene_30323
  
  DOI: 10.3389/fcell.2021.779169
  
  Resource: RRID:Addgene_30323
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8790513/
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 11 Aug 2021
  
  in Public
  
  Addgene_30323
  
  DOI: 10.1016/j.devcel.2017.10.027
  
  Resource: RRID:Addgene_30323
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5726799/
Jul 2021
www.cell.com www.cell.com

Untitled document

1
1. scibot 27 Jul 2021
  
  in Public
  
  Addgene_30323
  
  DOI: 10.1016/j.devcel.2017.10.027
  
  Resource: RRID:Addgene_30323
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

cell.com/developmental-cell/abstract/S1534-5807(17)30871-7
www.sciencedirect.com www.sciencedirect.com

Apoptotic cells represent a dynamic stem cell niche governing proliferation and tissue regeneration

1
1. scibot 01 Jul 2021
  
  in Public
  
  Addgene_30323
  
  DOI: 10.1016/j.devcel.2021.06.008
  
  Resource: RRID:Addgene_30323
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S153458072100486X
May 2021
www.sciencedirect.com www.sciencedirect.com

3D Culture Models with CRISPR Screens Reveal Hyperactive NRF2 as a Prerequisite for Spheroid Formation via Regulation of Proliferation and Ferroptosis

1
1. scibot 07 May 2021
  
  in Public
  
  Plasmid_30323
  
  DOI: 10.1016/j.molcel.2020.10.010
  
  Resource: RRID:Addgene_30323
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276520306936
Feb 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A novel function of R-spondin1 in regulating estrogen receptor expression independent of Wnt/β-catenin signaling

1
1. scibot 26 Feb 2021
  
  in Public
  
  RRID:Addgene_30323
  
  DOI: 10.7554/eLife.56434
  
  Resource: RRID:Addgene_30323
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323
Visit annotations in context

Tags

RRID:Addgene_30323

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7402675/
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer

1
1. scibot 13 Jan 2020
  
  in Public
  
  Addgene_30323
  
  DOI: 10.1016/j.devcel.2017.10.027
  
  Resource: RRID:Addgene_30323
  
  Curator: @Jmenke
  
  SciCrunch record: Addgene_30323
  
  What is this?
  
  RRID:Addgene_30323 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:Addgene_30323

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1534580717308717