61 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A feedforward loop between STAT1 and YAP1 stimulates lipid biosynthesis, accelerates tumor growth, and promotes chemotherapy resistance in mutant KRAS colorectal cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12378792/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting YAP/TAZ-TEAD signaling as a therapeutic approach in head and neck squamous cell carcinoma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12044704/
  4. Aug 2025
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SON-dependent nuclear speckle rehabilitation alleviates proteinopathies
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12325801/
  6. www.biorxiv.org www.biorxiv.org
    Regulation of YAP activity by nuclear G-actin binding
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2025.07.30.667612v1
  7. Jul 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Restriction of YWHAB-mediated YAP cytoplasmic retention is a novel mechanism underlying stemness maintenance and chemoresistance in ovarian cancer peritoneal metastasis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12221726/
  9. May 2025
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    VGLL2 and TEAD1 fusion proteins identified in human sarcoma drive YAP/TAZ-independent tumorigenesis by engaging EP300
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12061476/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    USP24 promotes hepatocellular carcinoma progression by deubiquitinating and stabilizing YAP1
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12034148/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRB2 Depletion Induces YAP Signaling and Disrupts Mechanosensing in Podocytes
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12076484/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The guanine nucleotide exchange factor Ric-8A regulates the sensitivity of constitutively active Gαq to the inhibitor YM-254890
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12033907/
  14. link.springer.com link.springer.com
    Microtubule associated serine/threonine kinase-3 inhibits the malignant phenotype of breast cancer by promoting phosphorylation-mediated ubiquitination degradation of yes-associated protein
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1186/s13058-025-02028-3
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Disrupting bile acid metabolism by suppressing Fxr causes hepatocellular carcinoma induced by YAP activation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12000370/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of Rho GEFs attenuates pulmonary fibrosis through suppressing myofibroblast activation and reprogramming profibrotic macrophages
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11992128/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genetically engineered secretory horseradish peroxidase is a sensitive, stable, and affordable non-lytic reporter gene system for real-time promoter activity management
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12012966/
  18. Apr 2025
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Vertical inhibition of p110α/AKT and N‐cadherin enhances treatment efficacy in PIK3CA‐aberrated ovarian cancer cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11977650/
  20. Mar 2025
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HDAC inhibitors modulate Hippo pathway signaling in hormone positive breast cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11863526/
  22. Feb 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Regulation of ER stress-induced apoptotic and inflammatory responses via YAP/TAZ-mediated control of the TRAIL-R2/DR5 signaling pathway
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11794427/
  24. Jan 2025
  25. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    CDK5 interacts with MST2 and modulates the Hippo signalling pathway
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.13962
  26. Dec 2024
  27. biosignaling.biomedcentral.com biosignaling.biomedcentral.com
    Transcriptional regulation of KCNA2 coding Kv1.2 by EWS::FLI1: involvement in controlling the YAP/Hippo signalling pathway and cell proliferation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biosignaling.biomedcentral.com/articles/10.1186/s12964-024-01981-4
  28. pubs.acs.org pubs.acs.org
    YAP/TAZ Inhibitor-Based Drug Delivery System for Selective Tumor Accumulation and Cancer Combination Therapy
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pubs.acs.org/doi/full/10.1021/acs.biomac.4c01076
  29. Sep 2024
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of zinc finger MIZ-type containing 2 as an oncoprotein enhancing NAD-dependent protein deacetylase sirtuin-1 deacetylase activity to regulate Wnt and Hippo pathways in non-small-cell lung cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11391738/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Retinoic acid-induced protein 14 links mechanical forces to Hippo signaling
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11387738/
  32. Aug 2024
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NEDD8 enhances Hippo signaling by mediating YAP1 neddylation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11327456/
  34. Jun 2024
  35. link.springer.com link.springer.com
    Urolithin A promotes atherosclerotic plaque stability by limiting inflammation and hypercholesteremia in Apolipoprotein E–deficient mice
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1038/s41401-024-01317-5
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VGLL2 and TEAD1 fusion proteins drive YAP/TAZ-independent transcription and tumorigenesis by engaging p300
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11092657/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    O-GlcNAcylation controls pro-fibrotic transcriptional regulatory signaling in myofibroblasts
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11148087/
  38. May 2024
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRIM21 is critical in regulating hepatocellular carcinoma growth and response to therapy by altering the MST1/YAP pathway
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11093211/
  40. Apr 2024
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR screens identify the YAP/TEAD axis as a driver of persister cells in EGFR mutant lung cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11043391/
  42. www.sciencedirect.com www.sciencedirect.com
    TM7SF3 controls TEAD1 splicing to prevent MASH-induced liver fibrosis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1550413124001232
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CSN6‐SPOP‐HMGCS1 Axis Promotes Hepatocellular Carcinoma Progression via YAP1 Activation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11005689/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting CD73 with flavonoids inhibits cancer stem cells and increases lymphocyte infiltration in a triple-negative breast cancer mouse model
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11004431/
  45. Mar 2024
  46. www.sciencedirect.com www.sciencedirect.com
    Fenofibrate-promoted hepatomegaly and liver regeneration are PPARα-dependent and partially related to the YAP pathway
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211383524001230
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNF166 promotes colorectal cancer progression by recognizing and destabilizing poly-ADP-ribosylated angiomotins
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10937711/
  48. Feb 2024
  49. aacrjournals.org aacrjournals.org
    A novel irreversible TEAD inhibitor, SWTX-143, blocks Hippo pathway transcriptional output and causes tumor regression in preclinical mesothelioma models
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    aacrjournals.org/mct/article/23/1/3/732154/A-Novel-Irreversible-TEAD-Inhibitor-SWTX-143
  50. Dec 2023
  51. link.springer.com link.springer.com
    The AMPK-Sirtuin 1-YAP axis is regulated by fluid flow intensity and controls autophagy flux in kidney epithelial cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1038/s41467-023-43775-1
  52. Oct 2023
  53. www.mdpi.com www.mdpi.com
    Role of the YAP/TAZ-TEAD Transcriptional Complex in the Metabolic Control of TRAIL Sensitivity by the Mevalonate Pathway in Cancer Cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    mdpi.com/2073-4409/12/19/2370
  54. 52.53.155.43 52.53.155.43
    mct-22-0681-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/d35db28aa1e833dc8bdcaa7cf7e7e23e3392038d/mct-22-0681-html.html
  55. Sep 2023
  56. dx.doi.org dx.doi.org
    Loss of CDKN2A Cooperates with WWTR1(TAZ)–CAMTA1 Gene Fusion to Promote Tumor Progression in Epithelioid Hemangioendothelioma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    dx.doi.org/10.1158/1078-0432.CCR-22-2497
  57. Jun 2023
  58. aacrjournals.org aacrjournals.org
    Interdependence of SS18-SSX-driven YAP1 and β-catenin activation in synovial sarcoma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    aacrjournals.org/mcr/article/21/6/535/726509/Interdependence-of-SS18-SSX-driven-YAP1-and
  59. Mar 2023
  60. www.sciencedirect.com www.sciencedirect.com
    Prolyl isomerase Pin1 promotes extracellular matrix production in hepatic stellate cells through regulating formation of the Smad3-TAZ complex
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0014482723000915
  61. Jan 2023
  62. www.biorxiv.org www.biorxiv.org
    YAP-dependent autophagy is controlled by AMPK, SIRT1 and flow intensity in kidney epithelial cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2023.01.09.523237v1
  63. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16007
  64. Sep 2022
  65. www.sciencedirect.com www.sciencedirect.com
    Virtual screening for small-molecule pathway regulators by image-profile matching
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2405471222003301
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    APE1 redox function is required for activation of Yes-associated protein 1 under reflux conditions in Barrett’s-associated esophageal adenocarcinomas
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC9434868/
  67. Nov 2021
  68. pubs.acs.org pubs.acs.org
    Inhibitors of the Hippo Pathway Kinases STK3/MST2 and STK4/MST1 Have Utility for the Treatment of Acute Myeloid Leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pubs.acs.org/doi/abs/10.1021/acs.jmedchem.1c00804
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Involvement of the TGF-β Signaling Pathway in the Development of YAP-Driven Osteosarcoma Lung Metastasis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC8576330/
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC8555985/
  71. Aug 2021
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC8313754/
  73. elifesciences.org elifesciences.org
    Systematic morphological profiling of human gene and allele function via Cell Painting
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    elifesciences.org/articles/24060
  74. Jul 2021
  75. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610819300431
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC6231326/
  77. academic.oup.com academic.oup.com
    Loss of Yap/taz in cardiac fibroblasts attenuates adverse remodeling and improves cardiac function
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/cardiovascres/advance-article-abstract/doi/10.1093/cvr/cvab205/6300518
  78. May 2021
  79. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    YAP1 Mediates Trametinib Resistance in Head and Neck Squamous Cell Carcinomas
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    clincancerres.aacrjournals.org/content/27/8/2326
  80. Mar 2021
  81. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15378
  82. Feb 2021
  83. www.mdpi.com www.mdpi.com
    The YAP/TEAD Axis as a New Therapeutic Target in Osteosarcoma: Effect of Verteporfin and CA3 on Primary Tumor Growth
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    mdpi.com/2072-6694/12/12/3847/htm
  84. www.oncotarget.com www.oncotarget.com
    A novel isoform of Homeodomain-interacting protein kinase-2 promotes YAP/TEAD transcriptional activity in NSCLC cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    oncotarget.com/article/27871/text/
  85. Jan 2021
  86. www.sciencedirect.com www.sciencedirect.com
    Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1934590920300941
  87. www.mdpi.com www.mdpi.com
    The YAP/TEAD Axis as a New Therapeutic Target in Osteosarcoma: Effect of Verteporfin and CA3 on Primary Tumor Growth
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    mdpi.com/2072-6694/12/12/3847/htm
  88. Dec 2020
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PNPLA3 I148M Up-Regulates Hedgehog and Yap Signaling in Human Hepatic Stellate Cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC7698885/
  90. Oct 2020
  91. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Chondroitin synthase‐3 regulates nucleus pulposus degeneration through actin‐induced YAP signaling
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202001021R
  92. Sep 2020
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC7112954/
  94. Jan 2020
  95. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610819300431