162 Matching Annotations
  1. Last 7 days
  2. www.molbiolcell.org www.molbiolcell.org
    Lipid scrambling via TMEM16F mediates the formation and release of extracellular vesicles
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    molbiolcell.org/doi/10.1091/mbc.E25-05-0245
  3. May 2026
  4. www.biorxiv.org www.biorxiv.org
    Otenabant is a Selective Antagonist of Human PIEZO1
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    biorxiv.org/content/10.64898/2026.04.28.720360v1
  5. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A Toolbox for Quantifying Nuclear and Nucleolar Protein Accumulation Using NLS and NoLS Fusion Reporters
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    onlinelibrary.wiley.com/doi/10.1111/tra.70036
  6. Apr 2026
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comprehensive profiling of CRISPR/dCas9 epigenome editors indicates a complex link between on and off target effects
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    pmc.ncbi.nlm.nih.gov/articles/PMC12924462/
  8. Mar 2026
  9. www.sciencedirect.com www.sciencedirect.com
    Regulatory T cell-derived TGF-β signaling governs the differentiation and maintenance of tumor-infiltrating bystander CD8+ T cells
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    sciencedirect.com/science/article/pii/S2211124726002676
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    Alanine catabolism as a targetable vulnerability for MYC-driven liver cancer
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    sciencedirect.com/science/article/pii/S2211124726001853
  11. Feb 2026
  12. www.sciencedirect.com www.sciencedirect.com
    CPSF73 activation and 3′ RNA polymerase II pausing are lost during readthrough transcription after heat shock
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    sciencedirect.com/science/article/pii/S2211124726001178
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Red-Light-Only Control of Protein–Protein Interactions Using a Cyanobacteriochrome (UNICYCL)
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    pmc.ncbi.nlm.nih.gov/articles/PMC12856669/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Optogenetic BlueGENEs engineered into a human safe harbor locus
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    pmc.ncbi.nlm.nih.gov/articles/PMC12802915/
  15. Jan 2026
  16. www.nature.com www.nature.com
    Xylosyltransferase engineering to manipulate proteoglycans in mammalian cells
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    nature.com/articles/s41589-025-02113-w
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Kallikrein 14 activates the chemoattractant protein chemerin in human skin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12796741/
  18. Dec 2025
  19. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Assessing Angiogenic Properties In Vitro or In Ovo of Pre-Crosslinked Alginate-Dialdehyde-Gelatin Hydrogels Incorporating Boron-Doped Mesoporous Bioactive Glass Particles
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    advanced.onlinelibrary.wiley.com/doi/10.1002/anbr.202500143
  20. Nov 2025
  21. 54.241.53.176 54.241.53.176
    thayer-et-al-2025-a-unified-mechanism-for-mitochondrial-damage-sensing-in-pink1-parkin-mediated-mitophagy-html.html
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    54.241.53.176/efd02b1a93da439b26b6ec3b31fa86116874758b/thayer-et-al-2025-a-unified-mechanism-for-mitochondrial-damage-sensing-in-pink1-parkin-mediated-mitophagy-html.html
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ATOH8 is crucial for the differentiation of human trophoblast stem cells into extravillous trophoblasts
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    pmc.ncbi.nlm.nih.gov/articles/PMC12586484/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protocol for hybrid mass spectrometry-AI mapping of proteasome-generated HLA class I epitopes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12590422/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DNA2 enables growth by restricting recombination-restarted replication
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    pmc.ncbi.nlm.nih.gov/articles/PMC12545200/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Synthetic Sponge System Against miRNAs of the miR-17/92 Cluster Targets Transcriptional MYC Dosage Compensation in Aneuploid Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12427730/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inducible tag-free degradation of endogenous proteins with AlissAID and development of a photoactivable inducer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12603123/
  27. Oct 2025
  28. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Arid1a Deficiency Drives Aristolochic Acid-Induced Liver Tumorigenesis through Ctnnb1 Mutation and Defective Nucleotide Excision Repair
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202513981
  29. www.biorxiv.org www.biorxiv.org
    Red-light-only control of protein-protein interactions using a cyanobacteriochrome (UNICYCL)
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    biorxiv.org/content/10.1101/2025.10.09.681461v1
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12515706/
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ARHGAP10 is a novel microtubule-associated protein that regulates the resorption activity of osteoclasts
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    pmc.ncbi.nlm.nih.gov/articles/PMC12509757/
  32. www.sciencedirect.com www.sciencedirect.com
    Phocaeicola vulgatus induces immunotherapy resistance in hepatocellular carcinoma via reducing indoleacetic acid production
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    sciencedirect.com/science/article/pii/S2666379125004434
  33. Sep 2025
  34. www.science.org www.science.org
    Linear ubiquitination prevents lipodystrophy and obesity-associated metabolic syndrome
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    science.org/doi/10.1126/sciadv.adw2539
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Linear ubiquitination prevents lipodystrophy and obesity-associated metabolic syndrome
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    pmc.ncbi.nlm.nih.gov/articles/PMC12442851/
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dual targeting of solid tumors using cytokine-induced killer cells modified with a CAR anti-tenascin C and a secretable EGFRxCD3 bispecific antibody
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    pmc.ncbi.nlm.nih.gov/articles/PMC12433391/
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Simvastatin overcomes the pPCK1‐pLDHA‐SPRINGlac axis‐mediated ferroptosis and chemo‐immunotherapy resistance in AKT‐hyperactivated intrahepatic cholangiocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12365544/
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GCDH Acetylation Orchestrates DNA Damage Response and Autophagy via Mitochondrial ROS to Suppress Hepatocellular Carcinoma Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12395558/
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The balance between B55α and Greatwall expression levels predicts sensitivity to Greatwall inhibition in cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12391391/
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Conversion of natural cytokine receptors into orthogonal synthetic biosensors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12380174/
  41. Aug 2025
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phosphoglycerate dehydrogenase stabilizes protein kinase C delta type mRNA to promote hepatocellular carcinoma progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12274589/
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Resolving native GABAA receptor structures from the human brain
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    pmc.ncbi.nlm.nih.gov/articles/PMC12103249/
  44. www.sciencedirect.com www.sciencedirect.com
    Integrator promotes the association of TFIID and RNA polymerase II to maintain pluripotency during development
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    sciencedirect.com/science/article/pii/S1097276525006070
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    Computational framework for prioritizing candidate compounds overcoming the resistance of pancancer immunotherapy
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    sciencedirect.com/science/article/pii/S2666379125003490
  46. www.sciencedirect.com www.sciencedirect.com
    Cargo-selective regulation of clathrin-mediated endocytosis by AMP-activated protein kinase
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    sciencedirect.com/science/article/pii/S2589004225013926
  47. Jul 2025
  48. www.sciencedirect.com www.sciencedirect.com
    Cancer immunology data engine reveals secreted AOAH as a potential immunotherapy
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    sciencedirect.com/science/article/pii/S0092867425007937
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Discovery of oligodendrocyte enhancers that regulate Sox10 expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12266436/
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NSUN2-mediated HCV RNA m5C Methylation Facilitates Viral RNA Stability and Replication
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    pmc.ncbi.nlm.nih.gov/articles/PMC12233092/
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Role of the Hexosamine-Sialic Acid Metabolic Pathway Mediated by GFPT1/NANS in c-Myc-Driven Hepatocellular Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12269569/
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Relaxin-2-secreting CAR-T cells exhibit enhanced efficacy in stromal-rich xenograft tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12259638/
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Serotonin receptor 5-HT2A as a potential target for HCC immunotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12186046/
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CD81 is a receptor for equine arteritis virus (family: Arteriviridae)
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    pmc.ncbi.nlm.nih.gov/articles/PMC12239600/
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HP1 loses its chromatin clustering and phase separation function across evolution
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    pmc.ncbi.nlm.nih.gov/articles/PMC12246093/
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Generation of a spontaneous murine HPV + oral cancer model with site-specific oncogene insertion using CRISPR-SONIC
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    pmc.ncbi.nlm.nih.gov/articles/PMC12175459/
  57. www.biorxiv.org www.biorxiv.org
    ARHGAP10 is a novel microtubule-associated protein that regulates the resorption activity of osteoclasts
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    biorxiv.org/content/10.1101/2025.06.12.659268v1
  58. Jun 2025
  59. journals.sagepub.com journals.sagepub.com
    A homozygous single-nucleotide variant in TNNT1 causes abnormal troponin T isoform expression in a patient with severe nemaline myopathy: A case report
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    journals.sagepub.com/doi/full/10.1177/22143602251339569
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ACE2 from Pipistrellus abramus bats is a receptor for HKU5 coronaviruses
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    pmc.ncbi.nlm.nih.gov/articles/PMC12119886/
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Precision multiplexed base editing in human cells using Cas12a-derived base editors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12126522/
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Induced Neural Progenitor Specification from Human Pluripotent Stem Cells by a Refined Synthetic Notch Platform
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    pmc.ncbi.nlm.nih.gov/articles/PMC12090341/
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The ubiquitin ligase NKLAM promotes apoptosis and suppression of cell growth
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    pmc.ncbi.nlm.nih.gov/articles/PMC12148440/
  64. May 2025
  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The bacterial type three secretion system induces mechanoporation of vacuolar membranes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12045489/
  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Predicting adenine base editing efficiencies in different cellular contexts by deep learning
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  67. 52.53.155.43 52.53.155.43
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  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Attenuating ABHD17 Isoforms Augments the S-acylation and Function of NOD2 and a Subset of Crohn’s Disease-associated NOD2 Variants
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    pmc.ncbi.nlm.nih.gov/articles/PMC12005342/
  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    VDAC2 loss elicits tumour destruction and inflammation for cancer therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12018455/
  70. Apr 2025
  71. aacrjournals.org aacrjournals.org
    METTL3-mediated m6A modification regulates the polycomb repressive complex 1 (PRC1) components BMI1 and RNF2 in hepatocellular carcinoma cells
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    aacrjournals.org/mcr/article/23/3/190/752031/METTL3-Mediated-m6A-Modification-Regulates-the
  72. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Influenza virus antagonizes self sensing by RIG-I to enhance viral replication
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    pmc.ncbi.nlm.nih.gov/articles/PMC11952396/
  73. Mar 2025
  74. www.sciencedirect.com www.sciencedirect.com
    Nuclear exclusion of condensin I in prophase coordinates mitotic chromosome reorganization to ensure complete sister chromatid resolution
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    sciencedirect.com/science/article/pii/S0960982225002118
  75. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Attenuating ABHD17 isoforms augments the S-acylation and function of NOD2 and a subset of Crohn’s disease-associated NOD2 variants
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    pmc.ncbi.nlm.nih.gov/articles/PMC10769251/
  76. www.biorxiv.org www.biorxiv.org
    Novel reporter of the PINK1-Parkin mitophagy pathway identifies its damage sensor in the import gate
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    biorxiv.org/content/10.1101/2025.02.19.639160v1
  77. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Unraveling enhanced liver regeneration in ALPPS: Integrating multi-omics profiling and in vivo CRISPR in mouse models
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    pmc.ncbi.nlm.nih.gov/articles/PMC11888979/
  78. www.sciencedirect.com www.sciencedirect.com
    Generation and GMP scale-up of human CAR-T cells using non-viral Sleeping Beauty transposons for B cell malignances
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    sciencedirect.com/science/article/pii/S2329050125000208
  79. Feb 2025
  80. www.sciencedirect.com www.sciencedirect.com
    Mutational pressure promotes release of public CD8+ T cell epitopes by proteasome from SARS-CoV-2 RBD of Omicron and its current lineages
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    sciencedirect.com/science/article/pii/S2589004225001336
  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High throughput analysis of rare nanoparticles with deep-enhanced sensitivity via unsupervised denoising
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    pmc.ncbi.nlm.nih.gov/articles/PMC11842628/
  82. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Live-Cell Imaging-Based Fluorescent SARS-CoV-2 Neutralization Assay by Antibody-Mediated Blockage of Receptor Binding Domain-ACE2 Interaction
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    pmc.ncbi.nlm.nih.gov/articles/PMC11843899/
  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Using the Sleeping Beauty Transposon System for Doxycycline-inducible Gene Expression in RAW264.7 Macrophage Cells to Study Phagocytosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11825295/
  84. aacrjournals.org aacrjournals.org
    Interferon-a potentiates anti-PD-1 efficacy by remodeling glucose metabolism in the hepatocellular carcinoma microenvironment
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    aacrjournals.org/cancerdiscovery/article/12/7/1718/705192/IFN-Potentiates-Anti-PD-1-Efficacy-by-Remodeling
  85. 52.53.155.43 52.53.155.43
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  86. Jan 2025
  87. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Generation of a genetically engineered porcine melanoma model featuring oncogenic control through conditional Cre recombination
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    pmc.ncbi.nlm.nih.gov/articles/PMC11724099/
  88. Dec 2024
  89. 52.53.155.43 52.53.155.43
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  90. Nov 2024
  91. 52.53.155.43 52.53.155.43
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  92. onlinelibrary.wiley.com onlinelibrary.wiley.com
    PPM1G Inhibits Epithelial–Mesenchymal Transition in Cholangiocarcinoma by Catalyzing TET1 Dephosphorylation for Destabilization to Impair Its Targeted Demethylation of the CLDN3 Promoter
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    onlinelibrary.wiley.com/doi/10.1002/advs.202407323
  93. Sep 2024
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In Vivo Tracking and 3D Mapping of Cell Death in Regeneration and Cancer Using Trypan Blue
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    ncbi.nlm.nih.gov/pmc/articles/PMC11352400/
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLC13A3 is a major effector downstream of activated β-catenin in liver cancer pathogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11364541/
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FDX1 downregulation activates mitophagy and the PI3K/AKT signaling pathway to promote hepatocellular carcinoma progression by inducing ROS production
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    ncbi.nlm.nih.gov/pmc/articles/PMC11366913/
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STUB1-mediated K63-linked ubiquitination of UHRF1 promotes the progression of cholangiocarcinoma by maintaining DNA hypermethylation of PLA2G2A
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    ncbi.nlm.nih.gov/pmc/articles/PMC11395162/
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional Activity of Cytokine-Induced Killer Cells Enhanced by CAR-CD19 Modification or by Soluble Bispecific Antibody Blinatumomab
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    ncbi.nlm.nih.gov/pmc/articles/PMC11417890/
  99. Aug 2024
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blockage of BCL-XL overcomes venetoclax resistance across BCL2+ lymphoid malignancies irrespective of BIM status
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    ncbi.nlm.nih.gov/pmc/articles/PMC11261020/
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oleic acid released by sensory neurons inhibits TRPV1-mediated thermal hypersensitivity via GPR40
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    ncbi.nlm.nih.gov/pmc/articles/PMC11338150/
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Soluble Tim-3 serves as a tumor prognostic marker and therapeutic target for CD8+ T cell exhaustion and anti-PD-1 resistance
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    ncbi.nlm.nih.gov/pmc/articles/PMC11384939/
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vivo interaction screening reveals liver-derived constraints to metastasis
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  166. Nov 2022
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  173. Jul 2022
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  175. Jun 2022
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  182. Dec 2021
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  188. Oct 2021
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  190. Sep 2021
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  192. Aug 2021
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  194. Jul 2021
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  200. Apr 2021
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  206. Feb 2021
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  208. Jan 2021
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  210. Sep 2020
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