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Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

TFEB overexpression alleviates autophagy-lysosomal deficits caused by progranulin insufficiency

2
1. scibot 11 Aug 2025
  
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  Addgene_38119
  
  DOI: 10.1038/s41598-025-12268-0
  
  Resource: RRID:Addgene_38119
  
  Curator: @scibot
  
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  RRID:Addgene_38119
2. scibot 11 Aug 2025
  
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  Addgene_3811955
  
  DOI: 10.1038/s41598-025-12268-0
  
  Resource: None
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_38119
  
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  RRIDCUR:Incorrect RRIDCUR:Unresolved RRID:Addgene_38119
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pmc.ncbi.nlm.nih.gov/articles/PMC12276339/
Jun 2025
www.nature.com www.nature.com

DMXL1 promotes recruitment of V1-ATPase to lysosomes upon TRPML1 activation

1
1. scibot 18 Jun 2025
  
  in Public
  
  Addgene, cat. no. 38119
  
  DOI: 10.1038/s41594-025-01581-x
  
  Resource: RRID:Addgene_38119
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:Addgene_38119
  
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  RRID:Addgene_38119
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nature.com/articles/s41594-025-01581-x
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CO confers neuroprotection via activating the PERK-calcineurin pathway and inhibiting necroptosis

1
1. scibot 15 Jun 2025
  
  in Public
  
  pEGFP-N1-TFEB
  
  DOI: 10.1038/s41420-025-02530-9
  
  Resource: RRID:Addgene_38119
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_38119
  
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  RRID:Addgene_38119
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pmc.ncbi.nlm.nih.gov/articles/PMC12116729/
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Ezrin defines TSC complex activation at endosomal compartments through EGFR–AKT signaling

1
1. scibot 16 Feb 2025
  
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  38119
  
  DOI: 10.7554/eLife.98523
  
  Resource: RRID:Addgene_38119
  
  Curator: @olekpark
  
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  RRID:Addgene_38119
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pmc.ncbi.nlm.nih.gov/articles/PMC11820125/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron

1
1. scibot 16 Feb 2025
  
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  38119
  
  DOI: 10.1038/s41598-025-89127-5
  
  Resource: RRID:Addgene_38119
  
  Curator: @olekpark
  
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  RRID:Addgene_38119
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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC11814099/
Jan 2025
www.sciencedirect.com www.sciencedirect.com

USP7 protects TFEB from proteasome-mediated degradation

1
1. scibot 30 Jan 2025
  
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  RRID:Addgene_38119
  
  DOI: 10.1016/j.celrep.2024.114872
  
  Resource: RRID:Addgene_38119
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:Addgene_38119
  
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  RRID:Addgene_38119
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scibot

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sciencedirect.com/science/article/pii/S2211124724012233
Dec 2024
www.cell.com www.cell.com

TFEB triggers a matrix degradation and invasion program in triple-negative breast cancer cells upon mTORC1 repression

1
1. scibot 29 Dec 2024
  
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  Addgene_38119
  
  DOI: 10.1016/j.devcel.2024.12.005
  
  Resource: RRID:Addgene_38119
  
  Curator: @scibot
  
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  RRID:Addgene_38119
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cell.com/developmental-cell/fulltext/S1534-5807(24)00727-5
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Transcription factor EB (TFEB) interaction with RagC is disrupted during enterovirus D68 infection

1
1. scibot 28 Dec 2024
  
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  plasmid_38119
  
  DOI: 10.1128/jvi.00556-24
  
  Resource: RRID:Addgene_38119
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_38119
  
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  RRID:Addgene_38119
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pmc.ncbi.nlm.nih.gov/articles/PMC11265353/
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Design and validation of a reporter mouse to study the dynamic regulation of TFEB and TFE3 activity through in vivo imaging techniques

1
1. scibot 25 Jul 2024
  
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  RRID:Addgene_38119
  
  DOI: 10.1080/15548627.2024.2334111
  
  Resource: RRID:Addgene_38119
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_38119
  
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  RRID:Addgene_38119
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ncbi.nlm.nih.gov/pmc/articles/PMC11262230/
link.springer.com link.springer.com

Truncated tau interferes with the autophagy and endolysosomal pathway and results in lipid accumulation

1
1. scibot 19 Jul 2024
  
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  plasmid_38119
  
  DOI: 10.1007/s00018-024-05337-6
  
  Resource: RRID:Addgene_38119
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_38119
  
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  RRID:Addgene_38119
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scibot

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link.springer.com/article/10.1007/s00018-024-05337-6
Feb 2024
www.sciencedirect.com www.sciencedirect.com

The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs

1
1. scibot 08 Feb 2024
  
  in Public
  
  Roczniak-Ferguson et al.6Addgene, Cat# 38119
  
  DOI: 10.1016/j.molcel.2024.01.012
  
  Resource: RRID:Addgene_38119
  
  Curator: @abever99
  
  SciCrunch record: RRID:Addgene_38119
  
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  RRID:Addgene_38119
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sciencedirect.com/science/article/pii/S1097276524000480
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

TFEB drives mTORC1 hyperactivation and kidney disease in Tuberous Sclerosis Complex

1
1. scibot 08 Feb 2024
  
  in Public
  
  Addgene_38119
  
  DOI: 10.1038/s41467-023-44229-4
  
  Resource: RRID:Addgene_38119
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_38119
  
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  RRID:Addgene_38119
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ncbi.nlm.nih.gov/pmc/articles/PMC10776564/
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The nutrient sensor mTORC1 regulates insulin secretion by modulating ß-cell autophagy

1
1. scibot 05 Mar 2023
  
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  RRID:Addgene_38119
  
  DOI: 10.2337/db21-0281
  
  Resource: RRID:Addgene_38119
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_38119
  
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  RRID:Addgene_38119
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scibot

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ncbi.nlm.nih.gov/pmc/articles/PMC8893949/
Jan 2023
www.nature.com www.nature.com

Transcription factor EB regulates phosphatidylinositol-3-phosphate levels that control lysosome positioning in the bladder cancer model

2
1. scibot 31 Jan 2023
  
  in Public
  
  plasmid_38119
  
  DOI: 10.1038/s42003-023-04501-1
  
  Resource: RRID:Addgene_38119
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_38119
  
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  RRID:Addgene_38119
2. scibot 31 Jan 2023
  
  in Public
  
  RRID:Addgene_38119n36
  
  DOI: 10.1038/s42003-023-04501-1
  
  Resource: RRID:Addgene_38119
  
  Curator: @a5munoz
  
  SciCrunch record: RRID:Addgene_38119
  
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  RRID:Addgene_38119 RRIDCUR:Unresolved
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RRID:Addgene_38119

RRIDCUR:Unresolved

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scibot

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nature.com/articles/s42003-023-04501-1
Jun 2022
rupress.org rupress.org

ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling

1
1. scibot 09 Jun 2022
  
  in Public
  
  RRID:Addgene_38119
  
  DOI: 10.1083/jcb.202106046
  
  Resource: RRID:Addgene_38119
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_38119
  
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  RRID:Addgene_38119
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rupress.org/jcb/article/221/7/e202106046/213259/ER-lysosome-lipid-transfer-protein-VPS13C-PARK23
onlinelibrary.wiley.com onlinelibrary.wiley.com

Pathogenic variants of Valosin Containing Protein induce lysosomal damage and transcriptional activation of autophagy regulators in neuronal cells

1
1. scibot 01 Jun 2022
  
  in Public
  
  RRID:Addgene_38119
  
  DOI: 10.1111/nan.12818
  
  Resource: RRID:Addgene_38119
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_38119
  
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  RRID:Addgene_38119
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onlinelibrary.wiley.com/doi/10.1111/nan.12818
Nov 2021
academic.oup.com academic.oup.com

Lysosomes and the pathogenesis of merosin-deficient congenital muscular dystrophy

1
1. scibot 18 Nov 2021
  
  in Public
  
  plasmid_38119
  
  DOI: 10.1093/hmg/ddab278
  
  Resource: RRID:Addgene_38119
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_38119
  
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  RRID:Addgene_38119
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RRID:Addgene_38119

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academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddab278/6374816
Sep 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

TFEB phosphorylation on Serine 211 is induced by autophagy in human synovial fibroblasts and by p62/SQSTM1 overexpression in HEK293 cells

1
1. scibot 18 Sep 2021
  
  in Public
  
  RRID:Addgene_38119
  
  DOI: 10.1042/BCJ20210174
  
  Resource: RRID:Addgene_38119
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_38119
  
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  RRID:Addgene_38119
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RRID:Addgene_38119

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scibot

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ncbi.nlm.nih.gov/pmc/articles/PMC8421036/
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 06 Aug 2021
  
  in Public
  
  plasmid_38119
  
  DOI: 10.1016/j.molcel.2017.04.027
  
  Resource: RRID:Addgene_38119
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_38119
  
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  RRID:Addgene_38119
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ncbi.nlm.nih.gov/pmc/articles/PMC5446411/
Dec 2020
www.cell.com www.cell.com

Lysosome Fusion Maintains Phagosome Integrity during Fungal Infection

1
1. scibot 11 Dec 2020
  
  in Public
  
  pEGFP-N1-TFEB
  
  DOI: 10.1016/j.chom.2020.09.004
  
  Resource: RRID:Addgene_38119
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_38119
  
  Curator comments: pEGFP-N1-TFEB
  
  What is this?
  
  RRIDCUR:Missing RRID:Addgene_38119
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RRID:Addgene_38119

RRIDCUR:Missing

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scibot

URL

cell.com/cell-host-microbe/fulltext/S1931-3128(20)30505-9
Nov 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41

1
1. scibot 14 Nov 2020
  
  in Public
  
  Addgene_38119
  
  DOI: 10.1016/j.celrep.2020.108371
  
  Resource: RRID:Addgene_38119
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_38119
  
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  RRID:Addgene_38119 RRIDCUR:Validated
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RRID:Addgene_38119

RRIDCUR:Validated

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scibot

URL

pubmed.ncbi.nlm.nih.gov/33176151/
Sep 2020
www.nature.com www.nature.com

Endocytic regulation of cellular ion homeostasis controls lysosome biogenesis

1
1. scibot 09 Sep 2020
  
  in Public
  
  RRID:Addgene_38119
  
  DOI: 10.1038/s41556-020-0535-7
  
  Resource: RRID:Addgene_38119
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_38119
  
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  RRID:Addgene_38119 RRIDCUR:Validated
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RRID:Addgene_38119

RRIDCUR:Validated

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scibot

URL

nature.com/articles/s41556-020-0535-7
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Brain-penetrant PQR620 mTOR and PQR530 PI3K/mTOR inhibitor reduce huntingtin levels in cell models of HD

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:Addgene_38119
  
  DOI: 10.1016/j.neuropharm.2019.107812
  
  Resource: RRID:Addgene_38119
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_38119
  
  What is this?
  
  RRID:Addgene_38119 RRIDCUR:Validated
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RRID:Addgene_38119

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S002839081930379X