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NOTCH1 S2513 is critical for the regulation of NICD levels impacting the segmentation clock in hiPSC-derived PSM cells and somitoids

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pmc.ncbi.nlm.nih.gov/articles/PMC12404203/
Aug 2025
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TFAP2A+ embryonic progenitor cells undergo fate diversification to give rise to human amnion, germline, and mesoderm

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pmc.ncbi.nlm.nih.gov/articles/PMC12262574/
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Phosphoinositide‐ and Collybistin‐Dependent Synaptic Clustering of Gephyrin

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1. scibot 11 Aug 2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12334862/
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Integrator promotes the association of TFIID and RNA polymerase II to maintain pluripotency during development

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sciencedirect.com/science/article/pii/S1097276525006070
Jul 2025
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Separation of telomere protection from length regulation by two different point mutations at amino acid 492 of RTEL1

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1. scibot 20 Jul 2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12203905/
Jun 2025
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Cell-context response to germ layer differentiation signals is predetermined by the epigenome in regionalized epiblast populations

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  DOI: 10.1038/s41467-025-60348-6
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12122723/
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Dual Ribosome Profiling reveals metabolic limitations of cancer and stromal cells in the tumor microenvironment

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  DOI: 10.1038/s41467-025-59986-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12089342/
May 2025
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PPDPF is not a key regulator of human pancreas development

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1. scibot 21 May 2025
  
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  DOI: 10.1371/journal.pgen.1011657
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12037078/
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Recombinant PRV Expressing GP3 and GP5 of PRRSV Provides Effective Protection Against Coinfection With PRV and PRRSV

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  plasmid_42335
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12081148/
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Kinome screening identifies integrated stress response kinase EIF2AK1/HRI as a negative regulator of PINK1 mitophagy signaling

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  DOI: 10.1126/sciadv.adn2528
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12063660/
Apr 2025
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FGFR2 residence in primary cilia is necessary for epithelial cell signaling

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1. scibot 24 Apr 2025
  
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  DOI: 10.1083/jcb.202311030
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12010920/
academic.oup.com academic.oup.com

Structure of the nucleosome-bound human BCL7A

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1. scibot 13 Apr 2025
  
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  DOI: 10.1093/nar/gkaf273
  
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academic.oup.com/nar/article/53/7/gkaf273/8109940
Mar 2025
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Opposing roles for Bmp signalling during the development of electrosensory lateral line organs

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1. scibot 28 Mar 2025
  
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  DOI: 10.7554/eLife.99798
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11936418/
Feb 2025
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TDP43 autoregulation gives rise to dominant negative isoforms that are tightly controlled by transcriptional and post-translational mechanisms

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1. scibot 26 Feb 2025
  
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  DOI: 10.1016/j.celrep.2024.115113
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11848802/
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Correction to “Development of BromoTag: A “Bump-and-Hole”–PROTAC System To Induce Potent, Rapid, and Selective Degradation of Tagged Target Proteins”

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1. scibot 24 Feb 2025
  
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  DOI: 10.1021/acs.jmedchem.5c00108
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11831586/
www.cell.com www.cell.com

CRISPR screening identifies regulators of enhancer-mediated androgen receptor transcription in advanced prostate cancer

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1. scibot 21 Feb 2025
  
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  Plasmid_42335
  
  DOI: 10.1016/j.celrep.2025.115312
  
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cell.com/cell-reports/fulltext/S2211-1247(25)00083-X
Sep 2024
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Cell type-specific dysregulation of gene expression due to Chd8 haploinsufficiency during mouse cortical development

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1. scibot 29 Sep 2024
  
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  DOI: 10.1101/2024.08.14.608000
  
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  RRID:Addgene_42335 DOI:10.1101/2024.08.14.608000
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ncbi.nlm.nih.gov/pmc/articles/PMC11343218/
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The characteristics of CTCF binding sequences contribute to enhancer blocking activity

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1. scibot 27 Sep 2024
  
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  DOI: 10.1093/nar/gkae666
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11417384/
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Dynamic chromatin architecture identifies new autoimmune-associated enhancers for IL2 and novel genes regulating CD4+ T cell activation

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1. scibot 27 Sep 2024
  
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  DOI: 10.7554/eLife.96852
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11418197/
Jun 2024
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Mitolnc controls cardiac BCAA metabolism and heart hypertrophy by allosteric activation of BCKDH

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ncbi.nlm.nih.gov/pmc/articles/PMC11194096/
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Cancer-associated MDM2 W329G mutant attenuates ribosomal stress-mediated p53 responses to promote cell survival and glycolysis

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ncbi.nlm.nih.gov/pmc/articles/PMC11162693/
May 2024
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ERLIN1/2 scaffolds bridge TMUB1 and RNF170 and restrict cholesterol esterification to regulate the secretory pathway

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  plasmid_42335
  
  DOI: 10.26508/lsa.202402620
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11116810/
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Mammalian RNAi represses pericentromeric lncRNAs to maintain genome stability

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  DOI: 10.1101/2024.05.09.593425
  
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biorxiv.org/content/10.1101/2024.05.09.593425v1
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Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism

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  DOI: 10.1016/j.molcel.2024.04.014
  
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sciencedirect.com/science/article/pii/S1097276524003290
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Generation of a human induced pluripotent stem cell line JHUi004-A with heterozygous mutation for spinocerebellar ataxia type 12 using genome editing

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sciencedirect.com/science/article/pii/S1873506124001399
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ERLIN1/2 scaffolds bridge TMUB1 and RNF170 and restrict cholesterol esterification to regulate the secretory pathway

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1. scibot 03 May 2024
  
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  DOI: 10.1101/2024.01.17.576039
  
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biorxiv.org/content/10.1101/2024.01.17.576039v1
Apr 2024
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Exploiting spatiotemporal regulation of FZD5 during neural patterning for efficient ventral midbrain specification

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  DOI: 10.1242/dev.202545
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10946437/
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STIM1 translocation to the nucleus protects cells from DNA damage

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  Plasmid_42335
  
  DOI: 10.1093/nar/gkae001
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10954485/
Mar 2024
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Generation of SST-P2A-mCherry reporter human embryonic stem cell line using the CRISPR/Cas9 system (WAe001-A-2C)

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1. scibot 27 Mar 2024
  
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  addgene_42335
  
  DOI: 10.1016/j.scr.2024.103397
  
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sciencedirect.com/science/article/pii/S1873506124000953
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Application of CRISPR/Cas9 for Rapid Genome Editing of Pseudorabies Virus and Bovine Herpesvirus-1

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  DOI: 10.3390/v16020311
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10892916/
Aug 2023
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Structural basis of branch site recognition by the human spliceosome

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  plasmid_42335
  
  DOI: 10.1126/science.abm4245
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7614990/
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Cohesin mediates DNA loop extrusion and sister chromatid cohesion by distinct mechanisms

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  DOI: 10.1016/j.molcel.2023.07.024
  
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sciencedirect.com/science/article/pii/S1097276523005671
Jun 2023
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Centromere/kinetochore is assembled through CENP-C oligomerization

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  DOI: 10.1016/j.molcel.2023.05.023
  
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sciencedirect.com/science/article/pii/S1097276523003799
May 2023
52.53.155.43 52.53.155.43

Necessity of HuR/ELAVL1 for activation-induced cytidine deaminase-dependent decrease in topoisomerase 1 in antibody diversification

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  DOI: 10.1093/intimm/dxad011
  
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52.53.155.43/48689241604aa0ddda1ea4c5de857e353548cf3a/dxad011-html.html
Feb 2023
www.nature.com www.nature.com

ADAMTS4 is involved in the production of the Alzheimer disease amyloid biomarker APP669-711

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1. scibot 04 Feb 2023
  
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  DOI: 10.1038/s41380-023-01946-y
  
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nature.com/articles/s41380-023-01946-y
elifesciences.org elifesciences.org

T-REX17 is a transiently expressed non-coding RNA essential for human endoderm formation

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1. scibot 02 Feb 2023
  
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  DOI: 10.7554/eLife.83077
  
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elifesciences.org/articles/83077
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Single-cell profiling of lncRNAs in human germ cells and molecular analysis reveals transcriptional regulation of LNC1845 on LHX8

1
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  DOI: 10.7554/eLife.78421
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9859043/
Nov 2022
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Reconstitution of human adrenocortical specification and steroidogenesis using induced pluripotent stem cells

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  RRID:Addgene_42335
  
  DOI: 10.1016/j.devcel.2022.10.010
  
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sciencedirect.com/science/article/pii/S1534580722007626
May 2022
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Myotubularin-related phosphatase 5 is a critical determinant of autophagy in neurons

2
1. scibot 19 May 2022
  
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  AddgeneCat#42335
  
  DOI: 10.1016/j.cub.2022.04.053
  
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Mar 2022
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CRISPR/Cas9-engineered human ES cells harboring heterozygous and homozygous c-KIT knockout

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  plasmid_42335
  
  DOI: 10.1016/j.scr.2022.102732
  
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Nov 2021
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Rescue of α-synuclein aggregation in Parkinson’s patient neurons by synergistic enhancement of ER proteostasis and protein trafficking

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1. scibot 18 Nov 2021
  
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  Cat #42335
  
  DOI: 10.1016/j.neuron.2021.10.032
  
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sciencedirect.com/science/article/pii/S089662732100862X
Oct 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Gene trapping reveals a new transcriptionally active genome element: the chromosome-specific clustered trap region

1
1. scibot 20 Oct 2021
  
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  RRID:Addgene_42335
  
  DOI: 10.1111/gtc.12890
  
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onlinelibrary.wiley.com/doi/10.1111/gtc.12890
Sep 2021
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Distinct roles of nonmuscle myosin II isoforms for establishing tension and elasticity during cell morphodynamics

2
1. scibot 04 Sep 2021
  
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  Addgene_42335
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8391736/
Aug 2021
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New hPSC SOX9 and INS Reporter Cell Lines Facilitate the Observation and Optimization of Differentiation into Insulin-Producing Cells

1
1. scibot 21 Aug 2021
  
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  RRID:Addgene_42335
  
  DOI: 10.1007/s12015-021-10232-9
  
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link.springer.com/article/10.1007/s12015-021-10232-9
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The DREAM complex through its subunit Lin37 cooperates with Rb to initiate quiescence

1
1. scibot 13 Aug 2021
  
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  plasmid_42335
  
  DOI: 10.7554/eLife.26876
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5602299/
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Untitled document

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  DOI: 10.1016/j.cmet.2018.07.005
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6224545/
Jul 2021
elifesciences.org elifesciences.org

Untitled document

1
1. scibot 31 Jul 2021
  
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  plasmid_42335
  
  DOI: 10.7554/eLife.26876
  
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elifesciences.org/articles/26876
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The Oncogenic Kaposi’s Sarcoma-Associated Herpesvirus Encodes a Mimic of the Tumor-Suppressive miR-15/16 miRNA Family

1
1. scibot 29 Jul 2021
  
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  RRID:Addgene_42335
  
  DOI: 10.1016/j.celrep.2019.11.005
  
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sciencedirect.com/science/article/pii/S2211124719314767
Apr 2021
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Generation of a human induced pluripotent stem cell line JHUi003-A with homozygous mutation for spinocerebellar ataxia type 12 using genome editing

1
1. scibot 21 Apr 2021
  
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  Addgene_42335
  
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sciencedirect.com/science/article/pii/S1873506121001926
Mar 2021
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Slc1a3-2A-CreERT2 mice reveal unique features of Bergmann glia and augment a growing collection of Cre drivers and effectors in the 129S4 genetic background

1
1. scibot 12 Mar 2021
  
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  RRID:Addgene_42335
  
  DOI: 10.1038/s41598-021-84887-2
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7940647/
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GATA transcription factors, SOX17 and TFAP2C, drive the human germ-cell specification program

1
1. scibot 09 Mar 2021
  
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  plasmid_42335
  
  DOI: 10.26508/lsa.202000974
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7918644/
Feb 2021
elifesciences.org elifesciences.org

Neural circuitry of a polycystin-mediated hydrodynamic startle response for predator avoidance

1
1. scibot 25 Feb 2021
  
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  plasmid_42335
  
  DOI: 10.7554/eLife.36262
  
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elifesciences.org/articles/36262
Dec 2020
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The role of glutamate oxaloacetate transaminases in sulfite biosynthesis and H2S metabolism

1
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  DOI: 10.1016/j.redox.2020.101800
  
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sciencedirect.com/science/article/pii/S2213231720310053
Nov 2020
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Essentiality of CENP-A Depends on Its Binding Mode to HJURP

1
1. scibot 26 Nov 2020
  
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  pX335
  
  DOI: 10.1016/j.celrep.2020.108388
  
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sciencedirect.com/science/article/pii/S2211124720313772
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Establishment of human immortalized mesenchymal stem cells lines for the monitoring and analysis of osteogenic differentiation in living cells

1
1. scibot 12 Nov 2020
  
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  RRID:Addgene_42335
  
  DOI: 10.1016/j.heliyon.2020.e05398
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7610338/
Sep 2020
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Activation of CpG-Rich Promoters Mediated by MLL Drives MOZ-Rearranged Leukemia

1
1. scibot 30 Sep 2020
  
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  Plasmid_42335
  
  DOI: 10.1016/j.celrep.2020.108200
  
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elifesciences.org elifesciences.org

Neural circuitry of a polycystin-mediated hydrodynamic startle response for predator avoidance

1
1. scibot 03 Sep 2020
  
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  Addgene_plasmid: #42335
  
  DOI: 10.7554/eLife.36262
  
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elifesciences.org/articles/36262
Jan 2020
elifesciences.org elifesciences.org

PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins

1
1. scibot 13 Jan 2020
  
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  Plasmid_42335
  
  DOI: 10.7554/eLife.50416
  
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elifesciences.org/articles/50416
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The inositol hexakisphosphate kinases IP6K1 and -2 regulate human cellular phosphate homeostasis, including XPR1-mediated phosphate export

1
1. scibot 13 Jan 2020
  
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  RRID:Addgene_42335
  
  DOI: 10.1074/jbc.RA119.007848
  
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jbc.org/content/294/30/11597.full
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SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance

1
1. scibot 13 Jan 2020
  
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  RRID:Addgene_42335
  
  DOI: 10.1016/j.molcel.2019.07.010
  
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sciencedirect.com/science/article/pii/S1097276519305404
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Induction of Sertoli-like cells from human fibroblasts by NR5A1 and GATA4

1
1. scibot 13 Jan 2020
  
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  Addgene_42335
  
  DOI: 10.7554/eLife.48767
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6881147/