Hypothesis

15 Matching Annotations

Oct 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Nrf1 coordinates proteasome activity and autophagy to maintain cardiac proteostasis

1
1. scibot 08 Oct 2026
  
  in Public
  
  Addgene_4587545
  
  DOI: 10.1038/s42003-026-10067-5
  
  Resource: RRID:Addgene_45875
  
  Curator: @Apiekniewska
  
  SciCrunch record: RRID:Addgene_45875
  
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  RRIDCUR:Unresolved RRID:Addgene_45875
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pmc.ncbi.nlm.nih.gov/articles/PMC13272659/
Sep 2026
www.sciencedirect.com www.sciencedirect.com

Lysyl oxidase inhibition disrupts mitochondrial homeostasis to create vulnerability to ferroptosis in TNBC

1
1. scibot 01 Sep 2026
  
  in Public
  
  RRID:Addgene_45875
  
  DOI: 10.1016/j.xcrm.2026.103015
  
  Resource: RRID:Addgene_45875
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_45875
  
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  RRID:Addgene_45875
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sciencedirect.com/science/article/pii/S2666379126004325
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Mutations in the Key Autophagy Tethering Factor EPG5 Link Neurodevelopmental and Neurodegenerative Disorders Including Early‐Onset Parkinsonism

1
1. scibot 24 Nov 2025
  
  in Public
  
  plasmid_45875
  
  DOI: 10.1002/ana.78013
  
  Resource: RRID:Addgene_45875
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_45875
  
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  RRID:Addgene_45875
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RRID:Addgene_45875

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12577676/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Parkin Induces Ubiquitination and Large Extracellular Vesicle Release of HMGB1 to Activate Antitumor Immunity

1
1. scibot 23 Nov 2025
  
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  45875
  
  DOI: 10.1158/0008-5472.CAN-25-0904
  
  Resource: RRID:Addgene_45875
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_45875
  
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  RRID:Addgene_45875
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pmc.ncbi.nlm.nih.gov/articles/PMC12495980/
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Induced Mitophagy Promotes Cell Cycle Re-Entry in Adult Cardiomyocytes

1
1. scibot 20 Jul 2025
  
  in Public
  
  Parkin-GFP
  
  DOI: 10.3390/cells14120853
  
  Resource: RRID:Addgene_45875
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_45875
  
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  RRID:Addgene_45875
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pmc.ncbi.nlm.nih.gov/articles/PMC12190997/
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Lysosomes drive the piecemeal removal of mitochondrial inner membrane

1
1. scibot 28 Sep 2024
  
  in Public
  
  plasmid_45875
  
  DOI: 10.1038/s41586-024-07835-w
  
  Resource: RRID:Addgene_45875
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_45875
  
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  RRID:Addgene_45875
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ncbi.nlm.nih.gov/pmc/articles/PMC7616637/
Apr 2023
www.sciencedirect.com www.sciencedirect.com

PHLPP1 regulates PINK1-parkin signalling and life span

1
1. scibot 15 Apr 2023
  
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  Plasmid_45875
  
  DOI: 10.1016/j.bbadis.2023.166718
  
  Resource: RRID:Addgene_45875
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_45875
  
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  RRID:Addgene_45875
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sciencedirect.com/science/article/pii/S0925443923000844
Feb 2023
aacrjournals.org aacrjournals.org

PINK1-mediated mitophagy promotes oxidative phosphorylation and redox homeostasis to induce drug-tolerant persister cancer cells

2
1. scibot 10 Feb 2023
  
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  RRID:Addgene_45875
  
  DOI: 10.1158/0008-5472.CAN-22-2370
  
  Resource: RRID:Addgene_45875
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_45875
  
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  RRID:Addgene_45875
2. scibot 10 Feb 2023
  
  in Public
  
  RRID:Addgene_45875
  
  DOI: 10.1158/0008-5472.CAN-22-2370
  
  Resource: RRID:Addgene_45875
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_45875
  
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  RRID:Addgene_45875
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aacrjournals.org/cancerres/article/83/3/398/716188/PINK1-Mediated-Mitophagy-Promotes-Oxidative
May 2022
www.sciencedirect.com www.sciencedirect.com

DRP1 levels determine the apoptotic threshold during embryonic differentiation through a mitophagy-dependent mechanism

2
1. scibot 25 May 2022
  
  in Public
  
  plasmid_45875
  
  DOI: 10.1016/j.devcel.2022.04.020
  
  Resource: RRID:Addgene_45875
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_45875
  
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  RRID:Addgene_45875
2. scibot 25 May 2022
  
  in Public
  
  RRID:Addgene_458
  
  DOI: 10.1016/j.devcel.2022.04.020
  
  Resource: RRID:Addgene_45875
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:Addgene_45875
  
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  RRID:Addgene_45875 RRIDCUR:Unresolved
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sciencedirect.com/science/article/pii/S1534580722003069
Jan 2022
www.sciencedirect.com www.sciencedirect.com

Discovery of small-molecule positive allosteric modulators of Parkin E3 ligase

1
1. scibot 06 Jan 2022
  
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  Addgene_45875
  
  DOI: 10.1016/j.isci.2021.103650
  
  Resource: RRID:Addgene_45875
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_45875
  
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  RRID:Addgene_45875
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sciencedirect.com/science/article/pii/S2589004221016205
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 27 Jul 2021
  
  in Public
  
  Addgene_45875
  
  DOI: 10.1016/j.molcel.2018.11.009
  
  Resource: RRID:Addgene_45875
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_45875
  
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  RRID:Addgene_45875
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sciencedirect.com/science/article/pii/S1097276518309791
Jun 2021
www.sciencedirect.com www.sciencedirect.com

An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of α-synuclein

1
1. scibot 09 Jun 2021
  
  in Public
  
  RRID:Addgene_45875
  
  DOI: 10.1016/j.celrep.2021.109189
  
  Resource: RRID:Addgene_45875
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_45875
  
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  RRID:Addgene_45875
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RRID:Addgene_45875

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sciencedirect.com/science/article/pii/S2211124721005350
Mar 2021
www.sciencedirect.com www.sciencedirect.com

Parkin is an E3 ligase for the ubiquitin-like modifier FAT10, which inhibits Parkin activation and mitophagy

1
1. scibot 17 Mar 2021
  
  in Public
  
  plasmid_45875
  
  DOI: 10.1016/j.celrep.2021.108857
  
  Resource: RRID:Addgene_45875
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_45875
  
  What is this?
  
  RRID:Addgene_45875
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RRID:Addgene_45875

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URL

sciencedirect.com/science/article/pii/S2211124721001716