30 Matching Annotations
  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Ctnnb1 enhancer transcriptionally regulates Wnt signaling dosage to balance homeostasis and tumorigenesis of intestinal epithelia
    1
    1. scibot 27 Sep 2024
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      DOI: 10.7554/eLife.98238

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    ncbi.nlm.nih.gov/pmc/articles/PMC11424096/
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhancer activation from transposable elements in extrachromosomal DNA
    1
    1. scibot 25 Sep 2024
      46911

      DOI: 10.1101/2024.09.04.611262

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    ncbi.nlm.nih.gov/pmc/articles/PMC11398463/
  4. Aug 2024
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel reporter for helicase activity in translation uncovers DDX3X interactions
    1
    1. scibot 13 Aug 2024
      46911

      DOI: 10.1261/rna.079837.123

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    ncbi.nlm.nih.gov/pmc/articles/PMC11251518/
  6. Jun 2024
  7. journals.plos.org journals.plos.org
    CRISPRi screen of long non-coding RNAs identifies LINC03045 regulating glioblastoma invasion
    1
    1. scibot 22 Jun 2024
      RRID:Addgene_46911

      DOI: 10.1371/journal.pgen.1011314

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    journals.plos.org/plosgenetics/article
  8. May 2024
  9. www.biorxiv.org www.biorxiv.org
    Single-cell multiomics reveals a gene regulatory circuit promoting leukemia cell differentiation
    1
    1. scibot 16 May 2024
      RRID:Addgene_46911

      DOI: 10.1101/2024.02.29.582681

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    biorxiv.org/content/10.1101/2024.02.29.582681v1
  10. Apr 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Improving prime editing with an endogenous small RNA-binding protein
    1
    1. scibot 23 Apr 2024
      46911

      DOI: 10.1038/s41586-024-07259-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC11023932/
  12. www.sciencedirect.com www.sciencedirect.com
    DDX21 mediates co-transcriptional RNA m6A modification to promote transcription termination and genome stability
    2
    1. scibot 04 Apr 2024
      Plasmid_46911

      DOI: 10.1016/j.molcel.2024.03.006

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    2. scibot 04 Apr 2024
      Plasmid_46911

      DOI: 10.1016/j.molcel.2024.03.006

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    sciencedirect.com/science/article/pii/S1097276524001886
  13. Mar 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integration of transcription regulation and functional genomic data reveals lncRNA SNHG6’s role in hematopoietic differentiation and leukemia
    1
    1. scibot 01 Mar 2024
      plasmid_46911

      DOI: 10.1186/s12929-024-01015-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC10900714/
  15. Feb 2024
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiplex single-cell chemical genomics reveals the kinase dependence of the response to targeted therapy
    1
    1. scibot 29 Feb 2024
      46911

      DOI: 10.1016/j.xgen.2023.100487

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    ncbi.nlm.nih.gov/pmc/articles/PMC10879025/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aneuploid embryonic stem cells drive teratoma metastasis
    1
    1. scibot 13 Feb 2024
      46911

      DOI: 10.1038/s41467-024-45265-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC10844504/
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanosensitive super-enhancers regulate genes linked to atherosclerosis in endothelial cells
    1
    1. scibot 01 Feb 2024
      46911

      DOI: 10.1083/jcb.202211125

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    ncbi.nlm.nih.gov/pmc/articles/PMC10794123/
  19. Jan 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large tandem duplications in cancer result from transcription and DNA replication collisions
    1
    1. scibot 30 Jan 2024
      plasmid_46911

      DOI: 10.1101/2023.05.17.23290140

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    ncbi.nlm.nih.gov/pmc/articles/PMC10802642/
  21. Oct 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation
    1
    1. scibot 28 Oct 2023
      RRID:Addgene_46911

      DOI: 10.1016/j.stem.2023.09.007

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    sciencedirect.com/science/article/pii/S1934590923003284
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Determinants of DDX3X sensitivity uncovered using a helicase activity in translation reporter
    1
    1. scibot 06 Oct 2023
      Addgene_46911

      DOI: 10.1101/2023.09.14.557805

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    ncbi.nlm.nih.gov/pmc/articles/PMC10515938/
  24. Mar 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Lipid peroxidation increases membrane tension, Piezo1 gating, and cation permeability to execute ferroptosis
    1
    1. scibot 10 Mar 2023
      Addgene_46911

      DOI: 10.1016/j.cub.2023.02.060

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    sciencedirect.com/science/article/pii/S0960982223002002
  26. Jan 2023
  27. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors
    1
    1. scibot 11 Jan 2023
      Addgene_46911

      DOI: 10.7554/eLife.81856

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    pubmed.ncbi.nlm.nih.gov/36576240/
  28. Nov 2022
  29. aacrjournals.org aacrjournals.org
    Resistance to ATR Inhibitors Is Mediated by Loss of the Nonsense-Mediated Decay Factor UPF2
    1
    1. scibot 18 Nov 2022
      RRID:Addgene_46911

      DOI: 10.1158/0008-5472.CAN-21-4335

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    aacrjournals.org/cancerres/article/82/21/3950/709947/Resistance-to-ATR-Inhibitors-Is-Mediated-by-Loss
  30. Feb 2022
  31. www.sciencedirect.com www.sciencedirect.com
    HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia
    1
    1. scibot 18 Feb 2022
      RRID:Addgene_46911

      DOI: 10.1016/j.molcel.2022.01.014

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    sciencedirect.com/science/article/pii/S1097276522000570
  32. Oct 2021
  33. www.sciencedirect.com www.sciencedirect.com
    A bipartite element with allele-specific functions safeguards DNA methylation imprints at the Dlk1-Dio3 locus
    1
    1. scibot 28 Oct 2021
      Plasmid_46911

      DOI: 10.1016/j.devcel.2021.10.004

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    sciencedirect.com/science/article/pii/S1534580721008054
  34. May 2021
  35. www.embopress.org www.embopress.org
    A stress-induced tyrosine-tRNA depletion response mediates codon-based translational repression and growth suppression
    1
    1. scibot 20 May 2021
      Addgene_46911

      DOI: 10.15252/embj.2020106696

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    embopress.org/doi/abs/10.15252/embj.2020106696
  36. onlinelibrary.wiley.com onlinelibrary.wiley.com
    In vivo CRISPR screening for novel noncoding RNA functional targets in glioblastoma models
    1
    1. scibot 18 May 2021
      RRID:Addgene_46911

      DOI: 10.1002/jnr.24850

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    onlinelibrary.wiley.com/doi/10.1002/jnr.24850
  37. www.sciencedirect.com www.sciencedirect.com
    Histone methyltransferase activity programs nuclear peripheral genome positioning
    1
    1. scibot 09 May 2021
      RRID:Addgene_46911

      DOI: 10.1016/j.ydbio.2020.07.010

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    sciencedirect.com/science/article/pii/S0012160620302062
  38. www.sciencedirect.com www.sciencedirect.com
    Conserved Functions of Ether Lipids and Sphingolipids in the Early Secretory Pathway
    1
    1. scibot 04 May 2021
      plasmid_46911

      DOI: 10.1016/j.cub.2020.07.059

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    sciencedirect.com/science/article/pii/S0960982220310848
  39. Apr 2021
  40. www.sciencedirect.com www.sciencedirect.com
    Illuminating Host-Mycobacterial Interactions with Genome-wide CRISPR Knockout and CRISPRi Screens
    1
    1. scibot 27 Apr 2021
      Addgene_46911

      DOI: 10.1016/j.cels.2020.08.010

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    sciencedirect.com/science/article/pii/S2405471220302945
  41. www.sciencedirect.com www.sciencedirect.com
    B cell-specific XIST complex enforces X-inactivation and restrains atypical B cells
    1
    1. scibot 27 Apr 2021
      Addgene_46911

      DOI: 10.1016/j.cell.2021.02.015

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    sciencedirect.com/science/article/pii/S0092867421001653
  42. Dec 2020
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TGFβ promotes widespread enhancer chromatin opening and operates on genomic regulatory domains
    1
    1. scibot 09 Dec 2020
      RRID:Addgene_46911

      DOI: 10.1038/s41467-020-19877-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC7713251/
  44. Jan 2020
  45. www.sciencedirect.com www.sciencedirect.com
    CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_46911

      DOI: 10.1016/j.neuron.2019.07.014

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      Curator: @ethanbadger

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      RRID:Addgene_46911 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0896627319306403
  46. elifesciences.org elifesciences.org
    PUMILIO, but not RBMX, binding is required for regulation of genomic stability by noncoding RNA NORAD
    1
    1. scibot 13 Jan 2020
      plasmid_46911

      DOI: 10.7554/eLife.48625

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    elifesciences.org/articles/48625
  47. www.sciencedirect.com www.sciencedirect.com
    HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_46911

      DOI: 10.1016/j.ccell.2019.10.011

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    sciencedirect.com/science/article/pii/S1535610819304854