51 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR/dCas9-TET1–mediated epigenetic editing reactivates miR-200c in breast cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12394620/
  3. Aug 2025
  4. www.sciencedirect.com www.sciencedirect.com
    Alternatively spliced isoforms of IRF7 differentially regulate interferon expression to tune response to viral infection
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    sciencedirect.com/science/article/pii/S2211124725009374
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    The small GTPase Ran defines nuclear pore complex asymmetry
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    sciencedirect.com/science/article/pii/S0092867425008141
  6. Jul 2025
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Unlocking the Puzzle of Mammalian Transfection: The Role of the RNA-sensing-Mediated Interferon Response in the Cellular Defense Against Foreign DNA Intrusion
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    pmc.ncbi.nlm.nih.gov/articles/PMC12210383/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Profiling crRNA architectures for enhanced Cas12 biosensing
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    pmc.ncbi.nlm.nih.gov/articles/PMC12182579/
  9. www.thelancet.com www.thelancet.com
    GWAS meta-analysis identifies five susceptibility loci for endometrial cancer
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    thelancet.com/journals/ebiom/article/PIIS2352-3964(25)00274-9/abstract
  10. Jun 2025
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    Phenotypic screens for SIRPA expression reveal RAB21 as a general regulator of macrophage surface identity
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    sciencedirect.com/science/article/pii/S2211124725006928
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Principles and functional consequences of plasmid chromatinization in mammalian cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12154926/
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    Protocol to screen chemicals to enhance homology-directed repair in CRISPR-Cas9 gene editing
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    sciencedirect.com/science/article/pii/S2666166725003028
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mitochondrial calcium signaling regulates branched-chain amino acid catabolism in fibrolamellar carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12118637/
  15. link.springer.com link.springer.com
    Application of CRISPR-Based Epigenome Editing Tools for Engineering Programmable Embryo Models
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    link.springer.com/protocol/10.1007/7651_2025_637
  16. May 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Recombinant PRV Expressing GP3 and GP5 of PRRSV Provides Effective Protection Against Coinfection With PRV and PRRSV
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    pmc.ncbi.nlm.nih.gov/articles/PMC12081148/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SAMD9 senses cytosolic double-stranded nucleic acids in epithelial and mesenchymal cells to induce antiviral immunity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12015307/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Induction of a transcriptional adaptation response by RNA destabilization events
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    pmc.ncbi.nlm.nih.gov/articles/PMC12069562/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Autophagy induction enhances homologous recombination-associated CRISPR–Cas9 gene editing
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    pmc.ncbi.nlm.nih.gov/articles/PMC11997770/
  21. Apr 2025
  22. www.sciencedirect.com www.sciencedirect.com
    Phosphorylation-dependent charge blocks regulate the relaxation of nuclear speckle networks
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    sciencedirect.com/science/article/pii/S1097276525002606
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    H1‐0 is a specific mediator of the repressive ETV6::RUNX1 transcriptional landscape in preleukemia and B cell acute lymphoblastic leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC11962653/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across five fly Parkinsonism models
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    pmc.ncbi.nlm.nih.gov/articles/PMC11968104/
  25. Mar 2025
  26. www.nature.com www.nature.com
    Spatial genomics of AAV vectors reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic cargo
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    nature.com/articles/s41587-025-02565-4
  27. Feb 2025
  28. www.sciencedirect.com www.sciencedirect.com
    mTOR-mediated p62/SQSTM1 stabilization confers a robust survival mechanism for ovarian cancer
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    sciencedirect.com/science/article/pii/S0304383525001296
  29. Jan 2025
  30. www.sciencedirect.com www.sciencedirect.com
    N6-methyladenosine in 5′ UTR does not promote translation initiation
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    sciencedirect.com/science/article/pii/S1097276523010742
  31. Dec 2024
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Engineered allogeneic T cells decoupling T-cell-receptor and CD3 signalling enhance the antitumour activity of bispecific antibodies
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    pmc.ncbi.nlm.nih.gov/articles/PMC11668682/
  33. Sep 2024
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR screenings identified SMCHD1 as a host-restricting factor for AAV transduction
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    ncbi.nlm.nih.gov/pmc/articles/PMC11257396/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Site in the UTY Gene as Safe Harbor Locus on the Y Chromosome of Pig
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    ncbi.nlm.nih.gov/pmc/articles/PMC11353466/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Impacts of Nucleosome Positioning Elements and Pre-Assembled Chromatin States on Expression and Retention of Transgenes
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    ncbi.nlm.nih.gov/pmc/articles/PMC11431089/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial dysfunction and increased reactive oxygen species production in MECP2 mutant astrocytes and their impact on neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC11374804/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Conserved regulatory motifs in the juxtamembrane domain and kinase N-lobe revealed through deep mutational scanning of the MET receptor tyrosine kinase domain
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    ncbi.nlm.nih.gov/pmc/articles/PMC11398868/
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    A candidate loss-of-function variant in SGIP1 causes synaptic dysfunction and recessive parkinsonism
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    sciencedirect.com/science/article/pii/S2666379124004798
  40. Aug 2024
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An activity-specificity trade-off encoded in human transcription factors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11321997/
  42. Jul 2024
  43. www.mdpi.com www.mdpi.com
    CRISPR Base Editing to Create Potential Charcot–Marie–Tooth Disease Models with High Editing Efficiency: Human Induced Pluripotent Stem Cell Harboring SH3TC2 Variants
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    mdpi.com/2227-9059/12/7/1550
  44. Jun 2024
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial Calcium Signaling Regulates Branched-Chain Amino Acid Catabolism in Fibrolamellar Carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11160645/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic Knock-Ins of Endogenous Fluorescent Tags in RAW 264.7 Murine Macrophages Using CRISPR/Cas9 Genome Editing
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    ncbi.nlm.nih.gov/pmc/articles/PMC10958172/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The egg-counter: a novel microfluidic platform for characterization of Caenorhabditis elegans egg-laying
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    ncbi.nlm.nih.gov/pmc/articles/PMC11131562/
  48. Apr 2024
  49. www.sciencedirect.com www.sciencedirect.com
    Protocol for efficient CRISPR-Cas9-mediated fluorescent tag knockin in hard-to-transfect erythroid cell lines
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    sciencedirect.com/science/article/pii/S2666166724001813
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    Temporal dynamics and stoichiometry in human Notch signaling from Notch synaptic complex formation to nuclear entry of the Notch intracellular domain
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    sciencedirect.com/science/article/pii/S1534580724001898
  51. Feb 2024
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of potential inhibitor against Leishmania donovani mitochondrial DNA primase through in-silico and in vitro drug repurposing approaches
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    ncbi.nlm.nih.gov/pmc/articles/PMC10853515/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Orthogonal LoxPsym sites allow multiplexed site-specific recombination in prokaryotic and eukaryotic hosts
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    ncbi.nlm.nih.gov/pmc/articles/PMC10850332/
  54. www.biorxiv.org www.biorxiv.org
    Comparative analysis of methodologies for detecting extrachromosomal circular DNA
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    biorxiv.org/content/10.1101/2023.12.01.569546v1
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HIV-1 Capsid Uncoating Is a Multistep Process That Proceeds through Defect Formation Followed by Disassembly of the Capsid Lattice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10832047/
  56. Jan 2024
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel Macrolide–Del-1 Axis to Regenerate Bone in Old Age
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    ncbi.nlm.nih.gov/pmc/articles/PMC10797555/
  58. Dec 2023
  59. www.sciencedirect.com www.sciencedirect.com
    Generation of a human embryonic stem cell reporter line, TMEM119-EGFP, for the visualisation of in vitro differentiated human microglia
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    sciencedirect.com/science/article/pii/S1873506123002507
  60. Aug 2023
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of branch site recognition by the human spliceosome
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    ncbi.nlm.nih.gov/pmc/articles/PMC7614990/
  62. Feb 2023
  63. www.cell.com www.cell.com
    Cell lineage-specific mitochondrial resilience during mammalian organogenesis
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    cell.com/cell/fulltext/S0092-8674(23)00093-4
  64. Dec 2022
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cell cycle-specific loading of condensin I is regulated by the N-terminal tail of its kleisin subunit
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    ncbi.nlm.nih.gov/pmc/articles/PMC9797191/
  66. Sep 2022
  67. www.sciencedirect.com www.sciencedirect.com
    Heterologous reporter expression in the planarian Schmidtea mediterranea through somatic mRNA transfection
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    sciencedirect.com/science/article/pii/S2667237522001801
  68. May 2022
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SEC is an antiangiogenic virulence factor that promotes Staphylococcus aureus endocarditis independent of superantigen activity
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    ncbi.nlm.nih.gov/pmc/articles/PMC9094652/
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    Analysis of the interplay between hepatitis B virus-positive hepatocytes and Kupffer cells ex vivo using mice as a model
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    sciencedirect.com/science/article/pii/S2666166722002441
  71. Jul 2021
  72. 52.53.155.43 52.53.155.43
    Type VI secretion system killing by commensal Neisseria is influenced by expression of type four pili
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    52.53.155.43/a570813de1916ab9208b79145b6ea8a8ec0c10db/elife-63755-v1-html.html
  73. Jun 2021
  74. www.sciencedirect.com www.sciencedirect.com
    Generation of locus-specific degradable tag knock-ins in mouse and human cell lines
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    sciencedirect.com/science/article/pii/S2666166721002823
  75. Mar 2021
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity
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    ncbi.nlm.nih.gov/pmc/articles/PMC7953441/
  77. Jan 2020
  78. www.sciencedirect.com www.sciencedirect.com
    Nuclear Pores Assemble from Nucleoporin Condensates During Oogenesis
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    sciencedirect.com/science/article/pii/S0092867419310736