753 Matching Annotations
  1. May 2021
  2. www.sciencedirect.com www.sciencedirect.com
    Pancreatic Cancer Cells Require the Transcription Factor MYRF to Maintain ER Homeostasis
    1
    1. scibot 05 May 2021
      Addgene_52961

      DOI: 10.1016/j.devcel.2020.09.011

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    sciencedirect.com/science/article/pii/S1534580720307139
  3. www.sciencedirect.com www.sciencedirect.com
    The Oncogenic PRL Protein Causes Acid Addiction of Cells by Stimulating Lysosomal Exocytosis
    1
    1. scibot 05 May 2021
      Plasmid_52961

      DOI: 10.1016/j.devcel.2020.08.009

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    sciencedirect.com/science/article/pii/S1534580720306675
  4. www.sciencedirect.com www.sciencedirect.com
    Glutamine Metabolism Controls Chondrocyte Identity and Function
    1
    1. scibot 04 May 2021
      Addgene plasmid repository #52961

      DOI: 10.1016/j.devcel.2020.05.001

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    sciencedirect.com/science/article/pii/S1534580720303579
  5. www.sciencedirect.com www.sciencedirect.com
    CRISPR/Cas9 deletion of ORMDLs reveals complexity in sphingolipid metabolism
    1
    1. scibot 04 May 2021
      plasmid_52961

      DOI: 10.1016/j.jlr.2021.100082

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    sciencedirect.com/science/article/pii/S002222752100064X
  6. www.sciencedirect.com www.sciencedirect.com
    Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis
    1
    1. scibot 01 May 2021
      Cat#52961

      DOI: 10.1016/j.cmet.2021.03.003

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    sciencedirect.com/science/article/pii/S1550413121001108
  7. Apr 2021
  8. www.sciencedirect.com www.sciencedirect.com
    Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans
    1
    1. scibot 30 Apr 2021
      Addgene_52961

      DOI: 10.1016/j.cmet.2020.10.020

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    sciencedirect.com/science/article/pii/S1550413120305532
  9. www.sciencedirect.com www.sciencedirect.com
    Functional Genomics Identifies Metabolic Vulnerabilities in Pancreatic Cancer
    1
    1. scibot 29 Apr 2021
      plasmid_52961

      DOI: 10.1016/j.cmet.2020.10.018

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    sciencedirect.com/science/article/pii/S1550413120305519
  10. www.sciencedirect.com www.sciencedirect.com
    Sequential CRISPR-Based Screens Identify LITAF and CDIP1 as the Bacillus cereus Hemolysin BL Toxin Host Receptors
    1
    1. scibot 28 Apr 2021
      Addgene_52961

      DOI: 10.1016/j.chom.2020.05.012

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    sciencedirect.com/science/article/pii/S1931312820302948
  11. www.sciencedirect.com www.sciencedirect.com
    Acetylation of Cytidine Residues Boosts HIV-1 Gene Expression by Increasing Viral RNA Stability
    1
    1. scibot 28 Apr 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.chom.2020.05.011

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    sciencedirect.com/science/article/pii/S1931312820302936
  12. www.sciencedirect.com www.sciencedirect.com
    Transcriptional control of DNA repair networks by CDK7 regulates sensitivity to radiation in MYC-driven medulloblastoma
    1
    1. scibot 28 Apr 2021
      Plasmid_52961

      DOI: 10.1016/j.celrep.2021.109013

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    sciencedirect.com/science/article/pii/S2211124721003272
  13. www.sciencedirect.com www.sciencedirect.com
    Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against Mycobacteria
    1
    1. scibot 24 Apr 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.cell.2020.10.046

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    sciencedirect.com/science/article/pii/S0092867420314537
  14. www.sciencedirect.com www.sciencedirect.com
    A Genetic Map of the Response to DNA Damage in Human Cells
    1
    1. scibot 23 Apr 2021
      Addgene Cat# 52961

      DOI: 10.1016/j.cell.2020.05.040

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    sciencedirect.com/science/article/pii/S0092867420306735
  15. www.sciencedirect.com www.sciencedirect.com
    MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway
    1
    1. scibot 22 Apr 2021
      Plasmid Cat#52961

      DOI: 10.1016/j.ccell.2020.11.004

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    sciencedirect.com/science/article/pii/S1535610820305961
  16. www.sciencedirect.com www.sciencedirect.com
    Isoform-specific and signaling-dependent propagation of acute myeloid leukemia by Wilms tumor 1
    1
    1. scibot 21 Apr 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2021.109010

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    sciencedirect.com/science/article/pii/S2211124721003247
  17. www.sciencedirect.com www.sciencedirect.com
    MAX Functions as a Tumor Suppressor and Rewires Metabolism in Small Cell Lung Cancer
    1
    1. scibot 17 Apr 2021
      Cat# 52961

      DOI: 10.1016/j.ccell.2020.04.016

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    sciencedirect.com/science/article/pii/S1535610820302154
  18. www.sciencedirect.com www.sciencedirect.com
    Immunogenomic Landscape of Hematological Malignancies
    1
    1. scibot 17 Apr 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.ccell.2020.06.002

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    sciencedirect.com/science/article/pii/S1535610820302750
  19. www.sciencedirect.com www.sciencedirect.com
    SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy
    1
    1. scibot 17 Apr 2021
      Addgene_52961

      DOI: 10.1016/j.ccell.2020.04.014

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    sciencedirect.com/science/article/pii/S1535610820302130
  20. www.sciencedirect.com www.sciencedirect.com
    The dystonia gene THAP1 controls DNA double-strand break repair choice
    1
    1. scibot 15 Apr 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.molcel.2021.03.034

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    sciencedirect.com/science/article/pii/S109727652100229X
  21. www.cell.com www.cell.com
    Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS
    1
    1. scibot 14 Apr 2021
      Plasmid_52961

      DOI: 10.1016/j.molcel.2021.02.033

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    cell.com/molecular-cell/fulltext/S1097-2765(21)00143-X
  22. www.sciencedirect.com www.sciencedirect.com
    Modulation of lanosterol synthase drives 24,25-epoxysterol synthesis and oligodendrocyte formation
    1
    1. scibot 12 Apr 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.chembiol.2021.01.025

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    sciencedirect.com/science/article/pii/S2451945621000519
  23. www.sciencedirect.com www.sciencedirect.com
    PAF remodels the DREAM complex to bypass cell quiescence and promote lung tumorigenesis
    1
    1. scibot 12 Apr 2021
      plasmid_52961

      DOI: 10.1016/j.molcel.2021.02.001

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    sciencedirect.com/science/article/pii/S1097276521000873
  24. journals.plos.org journals.plos.org
    Bronchial epithelial DNA methyltransferase 3b dampens pulmonary immune responses during Pseudomonas aeruginosa infection
    1
    1. scibot 06 Apr 2021
      RRID:Addgene_52961

      DOI: 10.1371/journal.ppat.1009491

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    journals.plos.org/plospathogens/article
  25. Mar 2021
  26. www.sciencedirect.com www.sciencedirect.com
    EPB41L5 controls podocyte extracellular matrix assembly by adhesome-dependent force transmission
    1
    1. scibot 24 Mar 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2021.108883

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    sciencedirect.com/science/article/pii/S2211124721001972
  27. www.sciencedirect.com www.sciencedirect.com
    DSB repair pathway choice is regulated by recruitment of 53BP1 through cell cycle-dependent regulation of Sp1
    1
    1. scibot 18 Mar 2021
      52961

      DOI: 10.1016/j.celrep.2021.108840

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    sciencedirect.com/science/article/pii/S2211124721001546
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Serial transplantation unmasks galectin-9 contribution to tumor immune escape in the MB49 murine model
    1
    1. scibot 10 Mar 2021
      RRID:Addgene_52961

      DOI: 10.1038/s41598-021-84270-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC7933353/
  29. www.sciencedirect.com www.sciencedirect.com
    The SPPL3-Defined Glycosphingolipid Repertoire Orchestrates HLA Class I-Mediated Immune Responses
    1
    1. scibot 08 Mar 2021
      Plasmid_52961

      DOI: 10.1016/j.immuni.2020.11.003

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    sciencedirect.com/science/article/pii/S1074761320304684
  30. www.sciencedirect.com www.sciencedirect.com
    Omnitemporal choreographies of all five STIM/Orai and IP3Rs underlie the complexity of mammalian Ca2+ signaling
    1
    1. scibot 03 Mar 2021
      Cat#52961

      DOI: 10.1016/j.celrep.2021.108760

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    sciencedirect.com/science/article/pii/S2211124721000735
  31. www.frontiersin.org www.frontiersin.org
    Novel Secreted Protein of Mycoplasma bovis MbovP280 Induces Macrophage Apoptosis Through CRYAB
    1
    1. scibot 03 Mar 2021
      RRID:Addgene_52961

      DOI: 10.3389/fimmu.2021.619362

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    frontiersin.org/article/10.3389/fimmu.2021.619362/full
  32. Feb 2021
  33. www.sciencedirect.com www.sciencedirect.com
    Reticulon-3 Promotes Endosome Maturation at ER Membrane Contact Sites
    1
    1. scibot 28 Feb 2021
      plasmid_52961

      DOI: 10.1016/j.devcel.2020.12.014

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    sciencedirect.com/science/article/pii/S1534580720310200
  34. www.pnas.org www.pnas.org
    The Ligand of Ate1 is intrinsically disordered and participates in nucleolar phase separation regulated by Jumonji Domain Containing 6
    1
    1. scibot 27 Feb 2021
      RRID:Addgene_52961

      DOI: 10.1073/pnas.2015887118

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    pnas.org/content/118/1/e2015887118
  35. www.nature.com www.nature.com
    Mapping effector genes at lupus GWAS loci using promoter Capture-C in follicular helper T cells
    1
    1. scibot 25 Feb 2021
      RRID:Addgene_52961

      DOI: 10.1038/s41467-020-17089-5

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    nature.com/articles/s41467-020-17089-5
  36. mct.aacrjournals.org mct.aacrjournals.org
    SLFN11 expression in advanced prostate cancer and response to platinum-based chemotherapy
    1
    1. scibot 25 Feb 2021
      RRID:Addgene_52961

      DOI: 10.1158/1535-7163.MCT-19-0926

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    mct.aacrjournals.org/content/19/5/1157
  37. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Proteasome inhibitors and Smac mimetics cooperate to induce cell death in Diffuse Large B‐cell Lymphoma by stabilizing NOXA and triggering mitochondrial apoptosis
    1
    1. scibot 25 Feb 2021
      Addgene_52961

      DOI: 10.1002/ijc.32976

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    onlinelibrary.wiley.com/doi/10.1002/ijc.32976
  38. journals.sagepub.com journals.sagepub.com
    A genome-wide CRISPR screen identifies regulation factors of the TLR3 signalling pathway - Laurent Zablocki-Thomas, Sam A Menzies, Paul J Lehner, Nicolas Manel, Philippe Benaroch,
    1
    1. scibot 25 Feb 2021
      plasmid_52961

      DOI: 10.1177/1753425920915507

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    journals.sagepub.com/doi/full/10.1177/1753425920915507
  39. www.nature.com www.nature.com
    Genome-wide CRISPR/Cas9-knockout in human induced Pluripotent Stem Cell (iPSC)-derived macrophages
    1
    1. scibot 25 Feb 2021
      RRID:Addgene_52961

      DOI: 10.1038/s41598-021-82137-z

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    nature.com/articles/s41598-021-82137-z
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RB1 Deletion in Retinoblastoma Protein Pathway-Disrupted Cells Results in DNA Damage and Cancer Progression
    1
    1. scibot 24 Feb 2021
      RRID:Addgene_52961

      DOI: 10.1128/MCB.00105-19

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    ncbi.nlm.nih.gov/pmc/articles/PMC6664603/
  41. www.sciencedirect.com www.sciencedirect.com
    Vitamin B6 Addiction in Acute Myeloid Leukemia
    1
    1. scibot 24 Feb 2021
      plasmid_52961

      DOI: 10.1016/j.ccell.2019.12.002

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    sciencedirect.com/science/article/pii/S1535610819305720
  42. www.cell.com www.cell.com
    TMEM41B IS A PAN-FLAVIVIRUS HOST FACTOR
    1
    1. scibot 24 Feb 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.cell.2020.12.005

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    cell.com/cell/abstract/S0092-8674(20)31627-5
  43. www.sciencedirect.com www.sciencedirect.com
    Cancer-associated exportin-6 upregulation inhibits the transcriptionally repressive and anticancer effects of nuclear profilin-1
    1
    1. scibot 24 Feb 2021
      Addgene_52961

      DOI: 10.1016/j.celrep.2021.108749

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    sciencedirect.com/science/article/pii/S2211124721000620
  44. www.sciencedirect.com www.sciencedirect.com
    High-Throughput Screens of PAM-Flexible Cas9 Variants for Gene Knockout and Transcriptional Modulation
    1
    1. scibot 13 Feb 2021
      plasmid_52961

      DOI: 10.1016/j.celrep.2020.02.010

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    sciencedirect.com/science/article/pii/S2211124720301649
  45. www.sciencedirect.com www.sciencedirect.com
    Loss of CHD1 Promotes Heterogeneous Mechanisms of Resistance to AR-Targeted Therapy via Chromatin Dysregulation
    1
    1. scibot 11 Feb 2021
      Plasmid_52961

      DOI: 10.1016/j.ccell.2020.03.001

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    sciencedirect.com/science/article/pii/S153561082030101X
  46. www.sciencedirect.com www.sciencedirect.com
    OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation
    1
    1. scibot 11 Feb 2021
      Addgene_52961

      DOI: 10.1016/j.celrep.2020.02.063

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    sciencedirect.com/science/article/pii/S221112472030231X
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein Kinase R Restricts the Intracellular Survival of Mycobacterium tuberculosis by Promoting Selective Autophagy
    1
    1. scibot 09 Feb 2021
      RRID:Addgene_52961

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  48. Jan 2021
  49. www.sciencedirect.com www.sciencedirect.com
    Optimized protocol for gene editing in adipocytes using CRISPR-Cas9 technology
    1
    1. scibot 29 Jan 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.xpro.2021.100307

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    sciencedirect.com/science/article/pii/S2666166721000149
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
    1
    1. scibot 29 Jan 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.cell.2020.12.006

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  51. www.sciencedirect.com www.sciencedirect.com
    Small-Molecule PAPD5 Inhibitors Restore Telomerase Activity in Patient Stem Cells
    1
    1. scibot 27 Jan 2021
      Addgene_52961

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    sciencedirect.com/science/article/pii/S1934590920301387
  52. www.sciencedirect.com www.sciencedirect.com
    hGBP1 Coordinates Chlamydia Restriction and Inflammasome Activation through Sequential GTP Hydrolysis
    1
    1. scibot 16 Jan 2021
      Addgene_52961

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  53. www.sciencedirect.com www.sciencedirect.com
    Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids
    1
    1. scibot 15 Jan 2021
      plasmid_52961

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  54. www.sciencedirect.com www.sciencedirect.com
    The Tumour Suppressor TMEM127 Is a Nedd4-Family E3 Ligase Adaptor Required by Salmonella SteD to Ubiquitinate and Degrade MHC Class II Molecules
    1
    1. scibot 15 Jan 2021
      Addgene_52961

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  55. www.sciencedirect.com www.sciencedirect.com
    A Nuclear Export Signal Is Required for cGAS to Sense Cytosolic DNA
    1
    1. scibot 08 Jan 2021
      RRID:Addgene_52961

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    sciencedirect.com/science/article/pii/S2211124720315758
  56. Dec 2020
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Salmonella enterica Infection of Murine and Human Enteroid-Derived Monolayers Elicits Differential Activation of Epithelium-Intrinsic Inflammasomes
    1
    1. scibot 25 Dec 2020
      RRID:Addgene_52961

      DOI: 10.1128/IAI.00017-20

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  58. www.sciencedirect.com www.sciencedirect.com
    FGF21 Induced by the ASK1-p38 Pathway Promotes Mechanical Cell Competition by Attracting Cells
    1
    1. scibot 24 Dec 2020
      lentiCRISPR v2

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    sciencedirect.com/science/article/pii/S0960982220317656
  59. www.sciencedirect.com www.sciencedirect.com
    Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD
    1
    1. scibot 17 Dec 2020
      Addgene_52961

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  60. www.cell.com www.cell.com
    Limiting Self-Renewal of the Basal Compartment by PKA Activation Induces Differentiation and Alters the Evolution of Mammary Tumors
    1
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    cell.com/developmental-cell/fulltext/S1534-5807(20)30794-2
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
    1
    1. scibot 09 Dec 2020
      Addgene_52961

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  62. www.nature.com www.nature.com
    Prohibitin, STAT3 and SH2D4A physically and functionally interact in tumor cell mitochondria
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    1. scibot 07 Dec 2020
      RRID:Addgene_52961

      DOI: 10.1038/s41419-020-03220-3

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  63. Nov 2020
  64. www.nature.com www.nature.com
    Raloxifene prevents stress granule dissolution, impairs translational control and promotes cell death during hypoxia in glioblastoma cells
    1
    1. scibot 24 Nov 2020
      plasmid_52961

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  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    UV damage induces G3BP1-dependent stress granule formation that is not driven by mTOR inhibition-mediated translation arrest
    1
    1. scibot 22 Nov 2020
      RRID:Addgene_52961

      DOI: 10.1242/jcs.248310

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  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Predicting Drug Response and Synergy Using a Deep Learning Model of Human Cancer Cells
    1
    1. scibot 18 Nov 2020
      RRID:Addgene_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC7737474/
  67. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41
    1
    1. scibot 14 Nov 2020
      Addgene_52961

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  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cutibacterium acnes Infection Induces Type I Interferon Synthesis Through the cGAS-STING Pathway
    1
    1. scibot 12 Nov 2020
      plasmid_52961

      DOI: 10.3389/fimmu.2020.571334

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    ncbi.nlm.nih.gov/pmc/articles/PMC7593769/
  69. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection
    1
    1. scibot 05 Nov 2020
      LentiCRISPRv2

      DOI: 10.1016/j.cell.2020.10.028

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  70. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Activation of Clustered IFNγ Target Genes Drives Cohesin-Controlled Transcriptional Memory
    1
    1. scibot 03 Nov 2020
      Addgene_52961

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    pubmed.ncbi.nlm.nih.gov/33108759/
  71. Oct 2020
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ovarian cancer cells direct monocyte differentiation through a non-canonical pathway
    1
    1. scibot 24 Oct 2020
      plasmid_52961

      DOI: 10.1186/s12885-020-07513-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC7568422/
  73. www.nature.com www.nature.com
    ERK3/MAPK6 is required for KRAS-mediated NSCLC tumorigenesis
    1
    1. scibot 21 Oct 2020
      plasmid_52961

      DOI: 10.1038/s41417-020-00245-w

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  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Most Commonly Mutated Genes in High-Grade Serous Ovarian Carcinoma Are Nonessential for Ovarian Surface Epithelial Stem Cell Transformation
    1
    1. scibot 14 Oct 2020
      plasmid_52961

      DOI: 10.1016/j.celrep.2020.108086

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    ncbi.nlm.nih.gov/pmc/articles/PMC7545232/
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis
    1
    1. scibot 13 Oct 2020
      RRID:Addgene_52961

      DOI: 10.7554/eLife.59442

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    ncbi.nlm.nih.gov/pmc/articles/PMC7541088/
  76. www.frontiersin.org www.frontiersin.org
    Priming Is Dispensable for NLRP3 Inflammasome Activation in Human Monocytes In Vitro
    1
    1. scibot 09 Oct 2020
      RRID:Addgene_52961

      DOI: 10.3389/fimmu.2020.565924

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    frontiersin.org/article/10.3389/fimmu.2020.565924/full
  77. Sep 2020
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Linker histone H1.2 and H1.4 affect the neutrophil lineage determination
    1
    1. scibot 26 Sep 2020
      RRID:Addgene_52961

      DOI: 10.7554/eLife.52563

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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of BLNK and BTK as mediators of rituximab‐induced programmed cell death by CRISPR screens in GCB‐subtype diffuse large B‐cell lymphoma
    1
    1. scibot 26 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1002/1878-0261.12753

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  80. journals.plos.org journals.plos.org
    Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells
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      RRID:Addgene_52961

      DOI: 10.1371/journal.pbio.3000606

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  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531
    1
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      RRID:Addgene_52961

      DOI: 10.7554/eLife.56913

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  82. www.sciencedirect.com www.sciencedirect.com
    Modeling Type 1 Diabetes In Vitro Using Human Pluripotent Stem Cells
    1
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      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2020.107894

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  83. journals.plos.org journals.plos.org
    TRIM34 restricts HIV-1 and SIV capsids in a TRIM5α-dependent manner
    1
    1. scibot 23 Sep 2020
      Addgene_52961

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  84. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Reticulon-3 modulates the incorporation of replication competent hepatitis C virus molecules for release inside infectious exosomes
    1
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      RRID:Addgene_52961

      DOI: 10.1371/journal.pone.0239153

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  85. www.sciencedirect.com www.sciencedirect.com
    Phosphorylated Lamin A/C in the Nuclear Interior Binds Active Enhancers Associated with Abnormal Transcription in Progeria
    1
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      plasmid_52961

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  86. www.sciencedirect.com www.sciencedirect.com
    Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells
    1
    1. scibot 17 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.molcel.2020.03.010

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  87. www.sciencedirect.com www.sciencedirect.com
    Early B Cell Factor Activity Controls Developmental and Adaptive Thermogenic Gene Programming in Adipocytes
    1
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      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2020.02.023

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    sciencedirect.com/science/article/pii/S2211124720301777
  88. www.sciencedirect.com www.sciencedirect.com
    A Switch in p53 Dynamics Marks Cells That Escape from DSB-Induced Cell Cycle Arrest
    1
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      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2020.107995

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    sciencedirect.com/science/article/pii/S2211124720309803
  89. www.sciencedirect.com www.sciencedirect.com
    DNA Methylation Regulates Alternative Polyadenylation via CTCF and the Cohesin Complex
    1
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      plasmid_52961

      DOI: 10.1016/j.molcel.2020.03.024

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  90. elifesciences.org elifesciences.org
    EDF1 coordinates cellular responses to ribosome collisions
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    1. scibot 16 Sep 2020
      RRID:Addgene_52961

      DOI: 10.7554/eLife.58828

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    elifesciences.org/articles/58828
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dengue Virus Serotype 2 and Its Non-Structural Proteins 2A and 2B Activate NLRP3 Inflammasome
    1
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      RRID:Addgene_52961

      DOI: 10.3389/fimmu.2020.00352

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    ncbi.nlm.nih.gov/pmc/articles/PMC7076137/
  92. www.sciencedirect.com www.sciencedirect.com
    Ribosome Recycling by ABCE1 Links Lysosomal Function and Iron Homeostasis to 3ʹ UTR-Directed Regulation and Nonsense-Mediated Decay
    1
    1. scibot 16 Sep 2020
      Addgene_52961

      DOI: 10.1016/j.celrep.2020.107895

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  93. elifesciences.org elifesciences.org
    Parvovirus Minute Virus of Mice Interacts with Sites of Cellular DNA Damage to Establish and Amplify its Lytic Infection
    1
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      plasmid_52961

      DOI: 10.7554/eLife.37750

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  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Splicing variation of BMP2K balances abundance of COPII assemblies and autophagic degradation in erythroid cells
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      plasmid_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC7473771/
  95. www.frontiersin.org www.frontiersin.org
    A20 Restricts Inflammatory Response and Desensitizes Gingival Keratinocytes to Apoptosis
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      DOI: 10.3389/fimmu.2020.00365

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    frontiersin.org/article/10.3389/fimmu.2020.00365/full
  96. www.sciencedirect.com www.sciencedirect.com
    Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance
    1
    1. scibot 14 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.stem.2020.02.007

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  97. academic.oup.com academic.oup.com
    Mitochondrial DNA mutations induce mitochondrial biogenesis and increase the tumorigenic potential of Hodgkin and Reed-Sternberg cells
    1
    1. scibot 13 Sep 2020
      plasmid_52961

      DOI: 10.1093/carcin/bgaa032

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    academic.oup.com/carcin/advance-article/doi/10.1093/carcin/bgaa032/5817053
  98. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Optimization of canine CD20 chimeric antigen receptor T cell manufacturing and in vitro cytotoxic activity against B cell lymphoma
    1
    1. scibot 13 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1111/vco.12602

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    onlinelibrary.wiley.com/doi/10.1111/vco.12602
  99. www.sciencedirect.com www.sciencedirect.com
    Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway
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    1. scibot 12 Sep 2020
      plasmid_52961

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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A pooled genome-wide screening strategy to identify and rank influenza host restriction factors in cell-based vaccine production platforms
    1
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      Addgene_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC7376217/
  101. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Enhancer RNAs predict enhancer–gene regulatory links and are critical for enhancer function in neuronal systems
    1
    1. scibot 10 Sep 2020
      plasmid_52961

      DOI: 10.1093/nar/gkaa671

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  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Formate induces a metabolic switch in nucleotide and energy metabolism
    1
    1. scibot 10 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1038/s41419-020-2523-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC7198490/
  103. www.sciencedirect.com www.sciencedirect.com
    Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis
    1
    1. scibot 09 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.stem.2019.11.016

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    sciencedirect.com/science/article/pii/S1934590919304710
  104. elifesciences.org elifesciences.org
    A virus-packageable CRISPR screen identifies host factors mediating interferon inhibition of HIV
    1
    1. scibot 09 Sep 2020
      Addgene_52961

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    elifesciences.org/articles/39823
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Recognition of Semaphorin Proteins by P. sordellii Lethal Toxin Reveals Principles of Receptor Specificity in Clostridial Toxins
    1
    1. scibot 09 Sep 2020
      plasmid_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC7316060/
  106. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model
    1
    1. scibot 09 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.devcel.2020.06.039

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    pubmed.ncbi.nlm.nih.gov/32710848/
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria
    1
    1. scibot 09 Sep 2020
      RRID:Addgene_52961

      DOI: 10.7554/eLife.58041

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    ncbi.nlm.nih.gov/pmc/articles/PMC7470841/
  108. www.jneurosci.org www.jneurosci.org
    Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk
    1
    1. scibot 08 Sep 2020
      plasmid_52961

      DOI: 10.1523/JNEUROSCI.2994-18.2019

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    jneurosci.org/content/39/37/7408
  109. journals.plos.org journals.plos.org
    Primate lentiviruses require Inositol hexakisphosphate (IP6) or inositol pentakisphosphate (IP5) for the production of viral particles
    1
    1. scibot 08 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1371/journal.ppat.1008646

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    journals.plos.org/plospathogens/article
  110. www.sciencedirect.com www.sciencedirect.com
    Rational Design of Allosteric and Selective Inhibitors of the Molecular Chaperone TRAP1
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    1. scibot 08 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2020.107531

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    sciencedirect.com/science/article/pii/S2211124720304319
  111. www.sciencedirect.com www.sciencedirect.com
    Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining
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    1. scibot 08 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2020.108068

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    sciencedirect.com/science/article/pii/S2211124720310536
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cells
    1
    1. scibot 07 Sep 2020
      plasmid_52961

      DOI: 10.1126/sciadv.aaz6699

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    ncbi.nlm.nih.gov/pmc/articles/PMC7299619/
  113. www.sciencedirect.com www.sciencedirect.com
    Endolysosomal Targeting of Mitochondria Is Integral to BAX-Mediated Mitochondrial Permeabilization during Apoptosis Signaling
    1
    1. scibot 07 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.devcel.2020.05.014

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    sciencedirect.com/science/article/pii/S1534580720304032
  114. bioone.org bioone.org
    Endogenous Retrovirus Activation as a Key Mechanism of Anti-Tumor Immune Response in Radiotherapy
    1
    1. scibot 06 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1667/RADE-20-00013

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    bioone.org/journals/radiation-research/volume-193/issue-4/RADE-20-00013/Endogenous-Retrovirus-Activation-as-a-Key-Mechanism-of-Anti-Tumor/10.1667/RADE-20-00013.full
  115. www.sciencedirect.com www.sciencedirect.com
    E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration
    1
    1. scibot 06 Sep 2020
      Plasmid_52961

      DOI: 10.1016/j.devcel.2019.12.016

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    sciencedirect.com/science/article/pii/S1534580719310391
  116. www.mdpi.com www.mdpi.com
    Multiple Functions of Fubp1 in Cell Cycle Progression and Cell Survival
    1
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      RRID:Addgene_52961

      DOI: 10.3390/cells9061347

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    mdpi.com/2073-4409/9/6/1347
  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ERK3/MAPK6 controls IL-8 production and chemotaxis
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    1. scibot 05 Sep 2020
      plasmid_52961

      DOI: 10.7554/eLife.52511

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    ncbi.nlm.nih.gov/pmc/articles/PMC7192585/
  118. www.jbc.org www.jbc.org
    Long noncoding RNA pncRNA-D reduces cyclin D1 gene expression and arrests cell cycle through RNA m6A modification
    1
    1. scibot 04 Sep 2020
      lenti-CRISPR-v2

      DOI: 10.1074/jbc.RA119.011556

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    jbc.org/content/295/17/5626.full
  119. www.sciencedirect.com www.sciencedirect.com
    Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity
    1
    1. scibot 04 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.immuni.2020.03.016

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    sciencedirect.com/science/article/pii/S1074761320301291
  120. www.sciencedirect.com www.sciencedirect.com
    Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis
    1
    1. scibot 03 Sep 2020
      Addgene Cat#52961

      DOI: 10.1016/j.stem.2020.04.001

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    sciencedirect.com/science/article/pii/S1934590920301405
  121. www.sciencedirect.com www.sciencedirect.com
    FTO Demethylates Cyclin D1 mRNA and Controls Cell-Cycle Progression
    1
    1. scibot 03 Sep 2020
      Addgene, Cat#52961

      DOI: 10.1016/j.celrep.2020.03.028

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    sciencedirect.com/science/article/pii/S2211124720303429
  122. www.sciencedirect.com www.sciencedirect.com
    A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome Instability
    1
    1. scibot 03 Sep 2020
      Addgene52961

      DOI: 10.1016/j.celrep.2020.01.020

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    sciencedirect.com/science/article/pii/S2211124720300292
  123. www.jbc.org www.jbc.org
    Regulation of poly(A)-specific ribonuclease activity by reversible lysine acetylation
    1
    1. scibot 03 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1074/jbc.RA120.012552

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    jbc.org/content/295/30/10255.full
  124. www.sciencedirect.com www.sciencedirect.com
    Targeting DGAT1 Ameliorates Glioblastoma by Increasing Fat Catabolism and Oxidative Stress
    1
    1. scibot 03 Sep 2020
      lentiCRISPR-v2

      DOI: 10.1016/j.cmet.2020.06.002

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    sciencedirect.com/science/article/pii/S155041312030303X
  125. www.sciencedirect.com www.sciencedirect.com
    Mutant p53 Drives Cancer Metastasis via RCP-Mediated Hsp90α Secretion
    1
    1. scibot 03 Sep 2020
      pLenti-CRISPR v2

      DOI: 10.1016/j.celrep.2020.107879

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    sciencedirect.com/science/article/pii/S2211124720308603
  126. www.sciencedirect.com www.sciencedirect.com
    Inhibition of MEK1/2 Forestalls the Onset of Acquired Resistance to Entrectinib in Multiple Models of NTRK1-Driven Cancer
    1
    1. scibot 03 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2020.107994

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    sciencedirect.com/science/article/pii/S2211124720309797
  127. www.sciencedirect.com www.sciencedirect.com
    Human GBP1 Differentially Targets Salmonella and Toxoplasma to License Recognition of Microbial Ligands and Caspase-Mediated Death
    1
    1. scibot 03 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2020.108008

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    sciencedirect.com/science/article/pii/S2211124720309931
  128. Aug 2020
  129. www.sciencedirect.com www.sciencedirect.com
    Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids
    1
    1. scibot 20 Aug 2020
      Addgene ID: 52961

      DOI: 10.1016/j.cell.2020.05.053

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    sciencedirect.com/science/article/pii/S0092867420306863
  130. www.sciencedirect.com www.sciencedirect.com
    Vitamin B6 Addiction in Acute Myeloid Leukemia
    1
    1. scibot 14 Aug 2020
      Addgene plasmid # 52961

      DOI: 10.1016/j.ccell.2019.12.002

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    sciencedirect.com/science/article/pii/S1535610819305720
  131. Jan 2020
  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sporadic and endemic Burkitt lymphoma have frequent FOXO1 mutations but distinct hotspots in the AKT recognition motif
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_52961

      DOI: 10.1182/bloodadvances.2018029546

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    ncbi.nlm.nih.gov/pmc/articles/PMC6650741/
  133. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Domain‐specific CD6 monoclonal antibodies identify CD6 isoforms generated by alternative‐splicing
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_52961

      DOI: 10.1111/imm.13087

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    onlinelibrary.wiley.com/doi/abs/10.1111/imm.13087
  134. www.sciencedirect.com www.sciencedirect.com
    PCIF1 Catalyzes m6Am mRNA Methylation to Regulate Gene Expression
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.molcel.2019.05.030

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    sciencedirect.com/science/article/pii/S1097276519304022
  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased expression of heme-binding protein 1 early in Alzheimer's disease is linked to neurotoxicity
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_52961

      DOI: 10.7554/eLife.47498

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  136. www.sciencedirect.com www.sciencedirect.com
    Low-Level Saturated Fatty Acid Palmitate Benefits Liver Cells by Boosting Mitochondrial Metabolism via CDK1-SIRT3-CPT2 Cascade
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      RRID:Addgene_52961

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  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Herpesviral lytic gene functions render the viral genome susceptible to novel editing by CRISPR/Cas9
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      DOI: 10.7554/eLife.51662

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  138. www.sciencedirect.com www.sciencedirect.com
    Aryl Sulfonamides Degrade RBM39 and RBM23 by Recruitment to CRL4-DCAF15
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      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2019.09.079

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  139. www.sciencedirect.com www.sciencedirect.com
    HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice
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      RRID:Addgene_52961

      DOI: 10.1016/j.ccell.2019.10.011

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  140. www.sciencedirect.com www.sciencedirect.com
    SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance
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      RRID:Addgene_52961

      DOI: 10.1016/j.molcel.2019.07.010

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  141. www.nature.com www.nature.com
    ATG5 cancer mutations and alternative mRNA splicing reveal a conjugation switch that regulates ATG12–ATG5-ATG16L1 complex assembly and autophagy
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      plasmid_52961

      DOI: 10.1038/s41421-019-0110-1

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  142. www.jbc.org www.jbc.org
    Adenosine deaminase acting on RNA-1 (ADAR1) inhibits HBV replication by enhancing microRNA-122 processing
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      RRID:Addgene_52961

      DOI: 10.1074/jbc.RA119.007970

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  143. www.sciencedirect.com www.sciencedirect.com
    Age-Related Gliosis Promotes Central Nervous System Lymphoma through CCL19-Mediated Tumor Cell Retention
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      RRID:Addgene_52961

      DOI: 10.1016/j.ccell.2019.08.001

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  144. academic.oup.com academic.oup.com
    The role of ZAP and OAS3/RNAseL pathways in the attenuation of an RNA virus with elevated frequencies of CpG and UpA dinucleotides
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_52961

      DOI: 10.1093/nar/gkz581

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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkz581/5528741
  145. www.sciencedirect.com www.sciencedirect.com
    CUB domain-containing protein 1 (CDCP1) binds transforming growth factor beta family members and increase TGF-β1 signaling pathway
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    1. scibot 13 Jan 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.yexcr.2019.111499

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  146. www.sciencedirect.com www.sciencedirect.com
    Tenovin-6 induces the SIRT-independent cell growth suppression and blocks autophagy flux in canine hemangiosarcoma cell lines
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      RRID:Addgene_52961

      DOI: 10.1016/j.yexcr.2019.111810

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  147. www.sciencedirect.com www.sciencedirect.com
    Endoplasmic reticulum-localized ECM1b suppresses tumor growth and regulates MYC and MTORC1 through modulating MTORC2 activation in esophageal squamous cell carcinoma
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      RRID:Addgene_52961

      DOI: 10.1016/j.canlet.2019.07.005

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    sciencedirect.com/science/article/pii/S030438351930401X
  148. www.sciencedirect.com www.sciencedirect.com
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      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2018.12.087

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  149. www.sciencedirect.com www.sciencedirect.com
    Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer
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      RRID:Addgene_52961

      DOI: 10.1016/j.ccell.2019.01.018

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  150. www.sciencedirect.com www.sciencedirect.com
    TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging
    1
    1. scibot 13 Jan 2020
      plasmid_52961

      DOI: 10.1016/j.cell.2018.07.041

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    sciencedirect.com/science/article/pii/S0092867418309693
  151. www.sciencedirect.com www.sciencedirect.com
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      Plasmid_52961

      DOI: 10.1016/j.cmet.2018.12.020

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  152. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      Addgene_52961

      DOI: 10.7554/eLife.39823

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    ncbi.nlm.nih.gov/pmc/articles/PMC6286125/
  153. www.sciencedirect.com www.sciencedirect.com
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      plasmid_52961

      DOI: 10.1016/j.cell.2018.12.012

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  154. www.sciencedirect.com www.sciencedirect.com
    The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment
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    1. scibot 13 Jan 2020
      Plasmid_52961

      DOI: 10.1016/j.immuni.2018.09.020

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  155. www.sciencedirect.com www.sciencedirect.com
    MicroRNA-Mediated Suppression of the TGF-β Pathway Confers Transmissible and Reversible CDK4/6 Inhibitor Resistance
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      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2019.02.023

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    sciencedirect.com/science/article/pii/S2211124719301937
  156. www.sciencedirect.com www.sciencedirect.com
    SLC19A1 Is an Importer of the Immunotransmitter cGAMP
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    1. scibot 13 Jan 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.molcel.2019.05.006

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  157. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.7554/eLife.41913

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  158. www.sciencedirect.com www.sciencedirect.com
    Genetic and Functional Dissection of the Role of Individual 5-HT2 Receptors as Entry Receptors for JC Polyomavirus
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      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2019.04.067

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  159. www.sciencedirect.com www.sciencedirect.com
    The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging
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    1. scibot 13 Jan 2020
      Addgene_52961

      DOI: 10.1016/j.molcel.2018.11.034

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    sciencedirect.com/science/article/pii/S1097276518310049
  160. www.sciencedirect.com www.sciencedirect.com
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      Addgene_52961

      DOI: 10.1016/j.cels.2017.10.010

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    sciencedirect.com/science/article/pii/S2405471217304477
  161. www.sciencedirect.com www.sciencedirect.com
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      Addgene_52961

      DOI: 10.1016/j.molcel.2018.12.008

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    sciencedirect.com/science/article/pii/S1097276518310621
  162. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      Addgene_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC6251713/
  163. www.sciencedirect.com www.sciencedirect.com
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      Plasmid_52961

      DOI: 10.1016/j.celrep.2018.09.071

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  164. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Neuron-Optimized CRISPR/dCas9 Activation System for Robust and Specific Gene Regulation
    1
    1. scibot 12 Jan 2020
      RRID:Addgene_52961

      DOI: 10.1523/ENEURO.0495-18.2019

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