400 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    ARAP2 regulates responses to interferon-gamma by restricting SOCS1
    2
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com:5037/science/article/pii/S2211124725014391
  3. Dec 2025
  4. 54.241.53.176 54.241.53.176
    2025.12.02.691971.full-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    54.241.53.176/695ba3cd832ab083eede24d6d780be9a3b357862/2025.12.02.691971.full-html.html
  5. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    FAME-CRISPR improves CRISPR-Cas9 genome editing via HDAC inhibition and engineered virus-like particle delivery
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com:5037/science/article/pii/S266723752500284X
  6. Nov 2025
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lysine-specific histone demethylase complex restricts Epstein-Barr virus lytic reactivation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12616731/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Enhancer activation from transposable elements in extrachromosomal DNA
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12611757/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A modular strategy for extracellular vesicle-mediated CRISPR-Cas9 delivery through aptamer-based loading and UV-activated cargo release
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12639036/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A microRNA CRISPR screen reveals microRNA-483-3p as an apoptotic regulator in prostate cancer cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12552650/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FRA1 (FOSL1) suppresses neoplastic transformation and modulates radiation responses via transcriptional control of mitogenic and stress-responsive networks
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12497744/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Up-regulating methylation of CAP1 promoter can promote apoptosis and inhibit migration and invasion of lung adenocarcinoma cells
    2
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12465864/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome editing or small molecule inhibition of KMT5A in CAR-T cells enhances antitumor immunity
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12519333/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bi-handed assembly chaperones regulate protein complex assembly through an intramolecular handover mechanism
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12429027/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Deciphering acquired resistance mechanisms to sustained auxin-inducible protein degradation in cells and mice
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12485725/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mycobacterium tuberculosis, Mycobacterium kansasii and Rhodococcus equi induce macrophage necroptosis in the presence of a caspase inhibitor acting on a non-canonical target(s)
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12424694/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Druggable genome CRISPR screening identifies the KEAP1/NRF2 axis as a mediator of PD-L1 expression
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12630863/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Class I histone deacetylases catalyze lysine lactylation[image]
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12624779/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PACT suppresses PKR activation through dsRNA binding and dimerization, and is a therapeutic target for triple-negative breast cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12530129/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RESTRICT-seq enables time-gated CRISPR screens and uncovers novel epigenetic dependencies of SCC resistance
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12458112/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Epstein-Barr Virus Latent Membrane Protein 1 targets cIAP1, cIAP2 and TRAF2 for Proteasomal Degradation to Activate the Non-canonical NF-κB Pathway
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12424949/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome-wide CRISPR screen identifies Menin and SUZ12 as regulators of human developmental timing
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12431854/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR screen identifies BAP1 as a deubiquitinase regulating SPIN4 stability
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12512048/
  24. www.sciencedirect.com www.sciencedirect.com
    Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0092867425012334
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    P selectin promotes SARS-CoV-2 interactions with platelets and the endothelium
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12618076/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome-wide screen in Mycobacterium tuberculosis infected macrophages reveals innate regulation of antibacterial mediators by IRF2
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12621954/
  27. www.biorxiv.org www.biorxiv.org
    Therapeutic Inducers of NK cell Killing (ThINKK)-induced NK cell cytotoxicity against childhood acute lymphoblastic leukemia: unraveling the dual role of TRAIL leads to the establishment of an efficacy biomarker
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2025.11.12.687655v1
  28. www.sciencedirect.com www.sciencedirect.com
    StealTHY: An immunogen-free CRISPR platform to expose concealed metastasis regulators in immunocompetent models
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0092867425011365
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SOCS1 Protects Acute Myeloid Leukemia against Allogeneic T Cell–Mediated Cytotoxicity
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12050964/
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cytidine deaminases APOBEC3C and APOBEC3D promote DNA replication stress resistance in pancreatic cancer cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12557688/
  31. Oct 2025
  32. www.sciencedirect.com www.sciencedirect.com
    Accumulation of succinate suppresses de novo purine synthesis through succinylation-mediated control of the mitochondrial folate cycle
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276525008196
  33. www.nature.com www.nature.com
    Inducible CRISPR–Cas9 screening platform to interrogate non-proliferative cellular states
    3
    Visit annotations in context

    Tags

    Annotators

    URL

    nature.com/articles/s41596-025-01251-8
  34. www.biorxiv.org www.biorxiv.org
    Parkinson’s disease LRRK2 mutations dysregulate iron homeostasis and promote oxidative stress and ferroptosis in human neurons and astrocytes
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2025.09.26.678370v1
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12485389/
  36. www.sciencedirect.com www.sciencedirect.com
    Biphasic control of the B cell transcriptome by mTORC1 and GSK3
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124725011325
  37. Sep 2025
  38. www.sciencedirect.com www.sciencedirect.com
    RSK1 reprograms the ubiquitin pathway to promote immune suppression
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124725010940
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neuropilin-2 upregulation by stromal TGFβ1 induces lung disseminated tumor cells dormancy escape and promotes metastasis outgrowth
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12446975/
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RBM39 degrader invigorates innate immunity to eradicate neuroblastoma despite cancer cell plasticity
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12443969/
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A compendium of synthetic lethal gene pairs defined by extensive combinatorial pan-cancer CRISPR screening
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12445041/
  42. www.science.org www.science.org
    Bi-handed assembly chaperones regulate protein complex assembly through an intramolecular handover mechanism
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    science.org/doi/10.1126/sciadv.adw9158
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Oxidative Phosphorylation is a Metabolic Vulnerability of Endocrine Therapy-Tolerant Persister Cells in ER+ Breast Cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11908958/
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    d-cysteine impairs tumour growth by inhibiting cysteine desulfurase NFS1
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12373508/
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Peroxisomal lipid metabolism inhibits Pimozide-induced cancer cell death by regulating ATP homeostasis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12371041/
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Insights into absence of lymphoma despite fulminant Epstein-Barr virus infection in patients with XIAP deficiency
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12406724/
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mitochondrial glutathione import enables breast cancer metastasis via integrated stress response signaling
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12396134/
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PTPN2 Inhibition Disrupts Mitochondrial Renewal and Blocks TFRC‐Mediated Mitophagy to Exert Anti‐Tumor Activities in ALK‐Positive Anaplastic Large Cell Lymphoma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12376625/
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pooled CRISPR screens identifies key regulators of bovine stem cell expansion for cultured meat
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12398484/
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular basis for shifted receptor recognition by an encephalitic arbovirus
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12406711/
  51. elifesciences.org elifesciences.org
    A Commander-independent function of COMMD3 in endosomal trafficking
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    elifesciences.org/articles/105264
  52. www.sciencedirect.com www.sciencedirect.com
    Epigenetic modulation of BARD1 to enhance anti-VEGF therapy
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2666379125004021
  53. www.nature.com www.nature.com
    Cytotoxicity of activator expression in CRISPR-based transcriptional activation systems
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    nature.com/articles/s41467-025-63570-4
  54. Aug 2025
  55. rupress.org rupress.org
    Perturbation of calreticulin potentiates CD8+ T cell–mediated antitumor immunity
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    rupress.org/jem/article/222/10/e20242360/278219/Perturbation-of-calreticulin-potentiates-CD8-T
  56. www.nature.com www.nature.com
    Tumor cell-adipocyte gap junctions activate lipolysis and contribute to breast tumorigenesis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    nature.com/articles/s41467-025-62486-3
  57. www.sciencedirect.com www.sciencedirect.com
    Loss of NOTCH2 creates a TRIM28-dependent vulnerability in small cell lung cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S153458072500499X
  58. www.sciencedirect.com www.sciencedirect.com
    SUCLG1 deficiency-induced histone succinylation impairs oncogene expression in acute myeloid leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124725009180
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Systematic comparison and base-editing-mediated directed protein evolution and functional screening yield superior auxin-inducible degron technology
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12274581/
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TAS-seq enables subcellular single-stranded adenosine profiling by signal peptide-assisted adenosine deamination
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12296453/
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Melanoma antigens in pediatric medulloblastoma contribute to tumor heterogeneity and species-specificity of group 3 tumors
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12302604/
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Removal of promoter CpG methylation by epigenome editing reverses HBG silencing
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12297318/
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single cell and spatial alternative splicing analysis with Nanopore long read sequencing
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12276307/
  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Directed evolution of novel AAV variants using the MCMS library for enhanced CNS tropism and reduced liver targeting in mice
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12272419/
  65. www.nature.com www.nature.com
    Murine hematopoietic progenitor cell lines with erythroid and megakaryocyte potential
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    nature.com/articles/s41467-025-62668-z
  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An enhanced Eco1 retron editor enables precision genome engineering in human cells without double-strand breaks
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12311787/
  67. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70080
  68. Jul 2025
  69. www.science.org www.science.org
    Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    science.org/doi/10.1126/sciadv.adu0847
  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    G6PC3 promotes genome maintenance and is a candidate mammary tumor suppressor
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12220951/
  71. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Image-based, pooled phenotyping reveals multidimensional, disease-specific variant effects
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12236469/
  72. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BRCA2 reversion mutation–independent resistance to PARP inhibition through impaired DNA prereplication complex function
    2
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12167974/
  73. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NINJ1 regulates plasma membrane fragility under mechanical strain
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12210241/
  74. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Epstein-Barr virus latent membrane protein 1 subverts IMPDH pathways to drive B-cell oncometabolism
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12169587/
  75. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR-BEasy: a free web-based service for designing sgRNA tiling libraries for CRISPR-dependent base editing screens
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12230738/
  76. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Leveraging CRISPR activation for rapid assessment of gene editing products in human pluripotent stem cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12181958/
  77. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Circular RNA landscape in extracellular vesicles from human biofluids
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11526565/
  78. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Hippo pathway promotes platinum-based chemotherapy by inhibiting MTF1-dependent heavy metal response
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11806854/
  79. www.biorxiv.org www.biorxiv.org
    EED Maintains the Small Cell Lung Cancer Neuroendocrine Phenotype and Drives Lung Cancer Histological Transformation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2025.07.07.663486v1
  80. www.sciencedirect.com www.sciencedirect.com
    An alternate receptor for adeno-associated viruses
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0092867425006920
  81. link.springer.com link.springer.com
    Spatiotemporally Resolved Profiling of Protein Movement by TransitID
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/protocol/10.1007/978-1-0716-4694-6_16
  82. Jun 2025
  83. www.sciencedirect.com www.sciencedirect.com
    Microprotein SMIM26 drives oxidative metabolism via serine-responsive mitochondrial translation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276525004721
  84. www.sciencedirect.com www.sciencedirect.com
    The immunoproteasome disturbs neuronal metabolism and drives neurodegeneration in multiple sclerosis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0092867425006166
  85. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The class II myosin MYH4 safeguards genome integrity and suppresses tumor progression
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12126247/
  86. www.science.org www.science.org
    In vivo CRISPR activation screen identifies acyl-CoA–binding protein as a driver of bone metastasis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    science.org/doi/10.1126/scitranslmed.ado7225
  87. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mitochondria regulate MR1 protein expression and produce self-metabolites that activate MR1-restricted T cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12107159/
  88. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Systemic genome-epigenome analysis captures a lineage-specific super-enhancer for MYB in gastrointestinal adenocarcinoma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12130324/
  89. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Elevated nonhomologous end-joining by AATF enables efficient DNA damage repair and therapeutic resistance in glioblastoma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12120020/
  90. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CEACAM1 as a mediator of B-cell receptor signaling in mantle cell lymphoma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12120064/
  91. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrative multi-omics identifies AP-1 transcription factor as a targetable mediator of acquired osimertinib resistance in non-small cell lung cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12104440/
  92. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SSRP1/SLC3A2 Axis in Arginine Transport: A New Target for Overcoming Immune Evasion and Tumor Progression in Peripheral T‐Cell Lymphoma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12140342/
  93. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome-wide CRISPR Screening Identifies NFκB and c-MET as Druggable Targets to Sensitize Lenvatinib Treatment in Hepatocellular Carcinoma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12140947/
  94. elifesciences.org elifesciences.org
    A Commander-independent function of COMMD3 in endosomal trafficking
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    elifesciences.org/reviewed-preprints/105264
  95. May 2025
  96. www.sciencedirect.com www.sciencedirect.com
    Targeting WEE1 in tumor-associated dendritic cells potentiates antitumor immunity via the cGAS/STING pathway
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124725005042
  97. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Systematic optimization of prime editing for enhanced efficiency and versatility in genome engineering across diverse cell types
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12069386/
  98. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Muscleblind-like proteins are novel modulators of the tumor-immune microenvironment
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12043120/
  99. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12017310/
  100. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome-wide CRISPR-Cas9 screens identify BCL family members as modulators of response to regorafenib in experimental glioma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12083232/
  101. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Protective Role of DUSP4 in Retinal Pigment Epithelium Senescence and Degeneration
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12027498/
  102. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Innovative evaluation of selinexor and JQ1 synergy in leukemia therapy via C-MYC inhibition
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12063270/
  103. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Perturb-tracing enables high-content screening of multi-scale 3D genome regulators
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12074983/
  104. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Depletion of Hepatic SREBP2 Protects Against Hypercholesterolemia and Atherosclerosis through the ANGPTL3-LPL Axis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12079391/
  105. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The regulatory architecture of the primed pluripotent cell state
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11982361/
  106. Apr 2025
  107. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70099
  108. www.sciencedirect.com www.sciencedirect.com
    Circular RMST cooperates with lineage-driving transcription factors to govern neuroendocrine transdifferentiation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S153561082500128X
  109. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    1-s2.0-S2589004225006480-main-html.html
    2
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12063144/
  110. www.sciencedirect.com www.sciencedirect.com
    ZEB2 is a master switch controlling the tumor-associated macrophage program
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610825001229
  111. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mycobacterium tuberculosis phagosome Ca2+ leakage triggers multimembrane ATG8/LC3 lipidation to restrict damage in human macrophages
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11939036/
  112. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A CRISPR-Cas9 screen reveals genetic determinants of the cellular response to decitabine
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11933316/
  113. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome-wide CRISPR screen identifies BUB1 kinase as a druggable vulnerability in malignant pleural mesothelioma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11968822/
  114. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular basis for shifted receptor recognition by an encephalitic arbovirus
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12406711/
  115. www.nature.com www.nature.com
    Lysine-arginine imbalance overcomes therapeutic tolerance governed by the transcription factor E3-lysosome axis in glioblastoma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    nature.com/articles/s41467-025-56946-z
  116. Mar 2025
  117. www.sciencedirect.com www.sciencedirect.com
    ACVR2A attenuation impacts lactate production and hyperglycolytic conditions attracting regulatory T cells in hepatocellular carcinoma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2666379125001119
  118. www.sciencedirect.com www.sciencedirect.com
    Amplified dosage of the NKX2-1 lineage transcription factor controls its oncogenic role in lung adenocarcinoma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276525001947
  119. www.sciencedirect.com www.sciencedirect.com
    The HAVCR1-centric host factor network drives Zika virus vertical transmission
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124725002359
  120. www.sciencedirect.com www.sciencedirect.com
    Lipid-metabolism-focused CRISPR screens identify enzymes of the mevalonate pathway as essential for prostate cancer growth
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124725002414
  121. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PHGDH activation fuels glioblastoma progression and radioresistance via serine synthesis pathway
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11921657/
  122. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome-wide CRISPR screen identifies IRF1 and TFAP4 as transcriptional regulators of Galectin-9 in T cell acute lymphoblastic leukemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11922064/
  123. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A genome wide CRISPR screen reveals novel determinants of long-lived plasma cell secretory capacity
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11888458/
  124. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Class I histone deacetylases catalyze lysine lactylation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11888385/
  125. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Succinate dehydrogenase activity supports de novo purine synthesis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11888382/
  126. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of JAK1 Function Causes G2/M Cell Cycle Defects Vulnerable to Kif18a Inhibition
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11888196/
  127. www.sciencedirect.com www.sciencedirect.com
    Simultaneous CRISPR screening and spatial transcriptomics reveal intracellular, intercellular, and functional transcriptional circuits
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0092867425001977
  128. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Divergent Requirements for Glutathione Biosynthesis During Osteoclast Differentiation In Vitro and In Vivo
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11851466/
  129. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Recognition of MR1-antigen complexes by TCR Vγ9Vδ2
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11876030/
  130. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Leveraging Circular Polymerization and Extension Cloning (CPEC) Method for Construction of CRISPR Screening Libraries
    2
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11865837/
  131. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Histone Demethylase LSD1/ZNF217/CoREST Complex is a Major Restriction Factor of Epstein-Barr Virus Lytic Reactivation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11774438/
  132. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Norovirus co-opts NINJ1 for selective protein secretion
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11870086/
  133. www.science.org www.science.org
    Epstein-Barr virus–driven cardiolipin synthesis sustains metabolic remodeling during B cell transformation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    science.org/doi/10.1126/sciadv.adr8837
  134. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Insights into the Absence of Lymphoma Despite Fulminant Epstein-Barr Virus Infection in Patients with XIAP Deficiency
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11761029/
  135. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting the mevalonate pathway potentiates NUAK1 inhibition-induced immunogenic cell death and antitumor immunity
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11866496/
  136. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CTCF is selectively required for maintaining chromatin accessibility and gene expression in human erythropoiesis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11869676/
  137. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Zinc Alleviates Diabetic Muscle Atrophy via Modulation of the SIRT1/FoxO1 Autophagy Pathway Through GPR39
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11873538/
  138. Feb 2025
  139. www.sciencedirect.com www.sciencedirect.com
    Variability in proliferative and migratory defects in Hirschsprung disease-associated RET pathogenic variants
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0002929725000515
  140. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Epigenetic priming promotes acquisition of tyrosine kinase inhibitor resistance and oncogene amplification in human lung cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11838195/
  141. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR screen reveals modifiers of rAAV production including known rAAV infection genes playing an unexpected role in vector production
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11840188/
  142. aacrjournals.org aacrjournals.org
    MR1 gene and protein expression are enhanced by inhibition of the extracellular signal-regulated kinase ERK
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    aacrjournals.org/cancerimmunolres/article/12/10/1452/748716/MR1-Gene-and-Protein-Expression-Are-Enhanced-by
  143. www.sciencedirect.com www.sciencedirect.com
    Ergothioneine controls mitochondrial function and exercise performance via direct activation of MPST
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1550413125000245
  144. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multidimensional, integrative profiling identifies BCL2L1 methylation as a predictor of MCL1 dependency in pediatric malignancies
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11790018/
  145. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The PRC2.1 subcomplex opposes G1 progression through regulation of CCND1 and CCND2
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11793871/
  146. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of selective SWI/SNF dependencies in enzalutamide-resistant prostate cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11794516/
  147. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Viral oncogene EBNALP regulates YY1 DNA binding and alters host 3D genome organization
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11811279/
  148. 52.53.155.43 52.53.155.43
    PDF-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/b6e42261d11f7c0ae043c89c64cba240f59a1523/PDF-html.html
  149. Jan 2025
  150. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NAC regulates metabolism and cell fate in intestinal stem cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11708876/
  151. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Knockout or inhibition of DHPS suppresses ovarian tumor growth and metastasis by attenuating the TGFβ pathway
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11704301/
  152. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Hira complex regulates Gli3R-dependent transcription in Hedgehog signaling and medulloblastoma cell growth and migration
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11697252/
  153. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular basis for shifted receptor recognition by an encephalitic arbovirus
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11722376/
  154. www.nature.com www.nature.com
    Targeting mitochondrial RNAs enhances the efficacy of the DNA-demethylating agents
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    nature.com/articles/s41598-024-80834-z
  155. Dec 2024
  156. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Gliocidin is a nicotinamide-mimetic prodrug that targets glioblastoma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11665509/
  157. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Base editing of Ptbp1 in neurons alleviates symptoms in a mouse model of Parkinson’s disease
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11666242/
  158. www.sciencedirect.com www.sciencedirect.com
    TurboCas: A method for locus-specific labeling of genomic regions and isolating their associated protein interactome
    2
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276524009122
  159. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Control of cell proliferation by memories of mitosis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11621110/
  160. Nov 2024
  161. www.biorxiv.org www.biorxiv.org
    Endocrine persistence in ER+ breast cancer is accompanied by metabolic vulnerability in oxidative phosphorylation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2024.09.26.615177v1
  162. www.sciencedirect.com www.sciencedirect.com
    Profound synthetic lethality between SMARCAL1 and FANCM
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276524008566
  163. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chromatin protein complexes involved in gene repression in lamina-associated domains
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11535540/
  164. Sep 2024
  165. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR screenings identified SMCHD1 as a host-restricting factor for AAV transduction
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11257396/
  166. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The histone methyltransferase KMT2D maintains cellular glucocorticoid responsiveness by shielding the glucocorticoid receptor from degradation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11350265/
  167. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phospholipid scrambling induced by an ion channel/metabolite transporter complex
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11366033/
  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multi-omic lineage tracing predicts the transcriptional, epigenetic and genetic determinants of cancer evolution
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11366763/
  169. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MYBL2 Drives Prostate Cancer Plasticity: Inhibiting Its Transcriptional Target CDK2 for RB1-Deficient Neuroendocrine Prostate Cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11368174/
  170. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The V-ATPase complex component RNAseK is required for lysosomal hydrolase delivery and autophagosome degradation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11374810/
  171. www.biorxiv.org www.biorxiv.org
    Clustered macrophages cooperate to eliminate tumors via coordinated intrudopodia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2024.09.19.613918v1
  172. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protocol for in vivo CRISPR screening targeting murine testicular cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11416641/
  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EspH utilizes phosphoinositide and Rab binding domains to interact with plasma membrane infection sites and Rab GTPases*
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11421376/
  174. www.sciencedirect.com www.sciencedirect.com
    Saturation mutagenesis-reinforced functional assays for disease-related genes
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0092867424009760
  175. www.biorxiv.org www.biorxiv.org
    Cytotoxicity of Activator Expression in CRISPR-based Transcriptional Activation Systems
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2024.09.23.614524v1
  176. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atrial fibrillation variant-to-gene prioritization through cross-ancestry eQTL and single-nucleus multiomic analyses
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11388022/
  177. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Host cell CRISPR genomics and modelling reveal shared metabolic vulnerabilities in the intracellular development of Plasmodium falciparum and related hemoparasites
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11271486/
  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhancer activation from transposable elements in extrachromosomal DNA
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11398463/
  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of resistance mechanisms to small-molecule inhibition of TEAD-regulated transcription
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11387499/
  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stem cells tightly regulate dead cell clearance to maintain tissue fitness
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11390485/
  181. www.sciencedirect.com www.sciencedirect.com
    Protein UFMylation regulates early events during ribosomal DNA-damage response
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124724010891
  182. www.sciencedirect.com www.sciencedirect.com
    MIG6 loss increased RET inhibitor tolerant persister cells in RET-rearranged non-small cell lung cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0304383524006153
  183. Aug 2024
  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas9 screening develops an epigenetic and transcriptional gene signature for risk stratification and target prediction in neuroblastoma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11338898/
  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Specific multivalent molecules boost CRISPR-mediated transcriptional activation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11341856/
  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Shifts in receptors during submergence of an encephalitic arbovirus
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11324528/
  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR screening uncovers a long-range enhancer for ONECUT1 in pancreatic differentiation and links a diabetes risk variant
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11406439/
  188. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Fanconi anemia core complex promotes CtIP-dependent end resection to drive homologous recombination at DNA double-strand breaks
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11329772/
  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis for VLDLR recognition by eastern equine encephalitis virus
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11297306/
  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The interferon γ pathway enhances pluripotency and X-chromosome reactivation in iPSC reprogramming
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11305397/
  191. www.biorxiv.org www.biorxiv.org
    An enhanced Eco1 retron editor enables precision genome engineering in human cells from a single-copy integrated lentivirus
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2024.08.05.606586v2
  192. www.cell.com www.cell.com
    Calcineurin is an adaptor required for assembly of the TCR signaling complex
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    cell.com/cell-reports/fulltext/S2211-1247(24)00897-0
  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11301402/
  194. www.cell.com www.cell.com
    SETDB1 suppresses NK cell-mediated immunosurveillance in acute myeloid leukemia with granulo-monocytic differentiation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    cell.com/cell-reports/fulltext/S2211-1247(24)00865-9
  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide Cas9-mediated screening of essential non-coding regulatory elements via libraries of paired single-guide RNAs
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11310080/
  196. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Library‐Assisted Evolution in Eukaryotic Cells Yield Adenine Base Editors with Enhanced Editing Specificity
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11321652/
  197. www.nature.com www.nature.com
    3D genomic analysis reveals novel enhancer-hijacking caused by complex structural alterations that drive oncogene overexpression
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    nature.com/articles/s41467-024-50387-w
  198. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A genome-wide CRISPR/Cas9 knockout screen identifies TMEM239 as an important host factor in facilitating African swine fever virus entry into early endosomes
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11288436/
  199. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Serine/arginine-rich splicing factor 7 promotes the type I interferon response by activating Irf7 transcription
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11056844/
  200. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    iNOS is necessary for GBP-mediated T. gondii clearance in murine macrophages via vacuole nitration and intravacuolar network collapse
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10973475/
  201. Jul 2024
  202. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Hippo pathway kinases LATS1 and 2 attenuate cellular responses to heavy metals through phosphorylating MTF1
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC9022944/
  203. www.embopress.org www.embopress.org
    DUSP6 inhibition overcomes neuregulin/HER3-driven therapy tolerance in HER2+ breast cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    embopress.org/doi/10.1038/s44321-024-00088-0
  204. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DUSP6 inhibition overcomes neuregulin/HER3-driven therapy tolerance in HER2+ breast cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11251193/
  205. www.biorxiv.org www.biorxiv.org
    Acute BRCAness Induction and AR Signaling Blockage through CDK12/7/9 Degradation Enhances PARP Inhibitor Sensitivity in Prostate Cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2024.07.09.602803v1
  206. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DUSP4 enhances therapeutic sensitivity in HER2-positive breast cancer by inhibiting the G6PD pathway and ROS metabolism by interacting with ALDOB
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11214528/
  207. Jun 2024
  208. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumour-derived Extracellular Vesicle and Particle Reprogramming of Interstitial Macrophages in the Lung Pre-Metastatic Niche Enhances Vascular Permeability and Metastatic Potential
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11160910/
  209. www.sciencedirect.com www.sciencedirect.com
    An enhancer RNA recruits KMT2A to regulate transcription of Myb
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S221112472400706X
  210. www.sciencedirect.com www.sciencedirect.com
    SpRY-mediated screens facilitate functional dissection of non-coding sequences at single-base resolution
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2666979X24001678
  211. www.sciencedirect.com www.sciencedirect.com
    STING orchestrates the neuronal inflammatory stress response in multiple sclerosis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0092867424005762