299 Matching Annotations
  1. Last 7 days
  2. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    1. scibot 19 Apr 2025
      52963; Addgene

      DOI: 10.1111/febs.70099

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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70099
  3. www.sciencedirect.com www.sciencedirect.com
    Circular RMST cooperates with lineage-driving transcription factors to govern neuroendocrine transdifferentiation
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    1. scibot 19 Apr 2025
      Addgene_52963

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    sciencedirect.com/science/article/pii/S153561082500128X
  4. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225006480-main-html.html
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    1. scibot 18 Apr 2025
      Addgene_52963

      DOI: 10.1016/j.isci.2025.112387

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    52.53.155.43/8c827978b6ff3a2dd4e3da9732b376046ff7b077/PDF-html.html
  5. Apr 2025
  6. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225006480-main-html.html
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    1. scibot 15 Apr 2025
      Addgene_52963

      DOI: 10.1016/j.isci.2025.112387

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    52.53.155.43/8c827978b6ff3a2dd4e3da9732b376046ff7b077/PDF-html.html
  7. www.sciencedirect.com www.sciencedirect.com
    ZEB2 is a master switch controlling the tumor-associated macrophage program
    1
    1. scibot 11 Apr 2025
      Addgene_52963

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    sciencedirect.com/science/article/pii/S1535610825001229
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mycobacterium tuberculosis phagosome Ca2+ leakage triggers multimembrane ATG8/LC3 lipidation to restrict damage in human macrophages
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    1. scibot 07 Apr 2025
      52963

      DOI: 10.1126/sciadv.adt3311

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    pmc.ncbi.nlm.nih.gov/articles/PMC11939036/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A CRISPR-Cas9 screen reveals genetic determinants of the cellular response to decitabine
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    1. scibot 07 Apr 2025
      52963

      DOI: 10.1038/s44319-025-00385-w

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    pmc.ncbi.nlm.nih.gov/articles/PMC11933316/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome-wide CRISPR screen identifies BUB1 kinase as a druggable vulnerability in malignant pleural mesothelioma
    1
    1. scibot 07 Apr 2025
      plasmid_52963

      DOI: 10.1038/s41419-025-07587-z

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    pmc.ncbi.nlm.nih.gov/articles/PMC11968822/
  11. www.sciencedirect.com www.sciencedirect.com
    Molecular basis for shifted receptor recognition by an encephalitic arbovirus
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    1. scibot 05 Apr 2025
      Addgene_52963

      DOI: 10.1016/j.cell.2025.03.029

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    sciencedirect.com/science/article/pii/S0092867425003472
  12. www.nature.com www.nature.com
    Lysine-arginine imbalance overcomes therapeutic tolerance governed by the transcription factor E3-lysosome axis in glioblastoma
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    1. scibot 03 Apr 2025
      RRID:Addgene_52963

      DOI: 10.1038/s41467-025-56946-z

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    nature.com/articles/s41467-025-56946-z
  13. Mar 2025
  14. www.sciencedirect.com www.sciencedirect.com
    ACVR2A attenuation impacts lactate production and hyperglycolytic conditions attracting regulatory T cells in hepatocellular carcinoma
    1
    1. scibot 29 Mar 2025
      AddgeneCat# 52963

      DOI: 10.1016/j.xcrm.2025.102038

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    sciencedirect.com/science/article/pii/S2666379125001119
  15. www.sciencedirect.com www.sciencedirect.com
    Amplified dosage of the NKX2-1 lineage transcription factor controls its oncogenic role in lung adenocarcinoma
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    1. scibot 29 Mar 2025
      RRID:Addgene_52963

      DOI: 10.1016/j.molcel.2025.03.001

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    sciencedirect.com/science/article/pii/S1097276525001947
  16. www.sciencedirect.com www.sciencedirect.com
    The HAVCR1-centric host factor network drives Zika virus vertical transmission
    1
    1. scibot 29 Mar 2025
      RRID:Addgene_52963

      DOI: 10.1016/j.celrep.2025.115464

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    sciencedirect.com/science/article/pii/S2211124725002359
  17. www.sciencedirect.com www.sciencedirect.com
    Lipid-metabolism-focused CRISPR screens identify enzymes of the mevalonate pathway as essential for prostate cancer growth
    1
    1. scibot 28 Mar 2025
      AddgeneCat# 52963

      DOI: 10.1016/j.celrep.2025.115470

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    sciencedirect.com/science/article/pii/S2211124725002414
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PHGDH activation fuels glioblastoma progression and radioresistance via serine synthesis pathway
    1
    1. scibot 23 Mar 2025
      Lenti-Guide-puro

      DOI: 10.1186/s13046-025-03361-3

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    pmc.ncbi.nlm.nih.gov/articles/PMC11921657/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome-wide CRISPR screen identifies IRF1 and TFAP4 as transcriptional regulators of Galectin-9 in T cell acute lymphoblastic leukemia
    1
    1. scibot 23 Mar 2025
      52963

      DOI: 10.1126/sciadv.ads8351

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    pmc.ncbi.nlm.nih.gov/articles/PMC11922064/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A genome wide CRISPR screen reveals novel determinants of long-lived plasma cell secretory capacity
    1
    1. scibot 23 Mar 2025
      52963

      DOI: 10.1101/2025.02.28.640639

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    pmc.ncbi.nlm.nih.gov/articles/PMC11888458/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Class I histone deacetylases catalyze lysine lactylation
    1
    1. scibot 23 Mar 2025
      52963

      DOI: 10.1101/2025.02.25.640220

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    pmc.ncbi.nlm.nih.gov/articles/PMC11888385/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Succinate dehydrogenase activity supports de novo purine synthesis
    1
    1. scibot 23 Mar 2025
      Addgene_52963

      DOI: 10.1101/2025.02.26.640389

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    pmc.ncbi.nlm.nih.gov/articles/PMC11888382/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of JAK1 Function Causes G2/M Cell Cycle Defects Vulnerable to Kif18a Inhibition
    1
    1. scibot 23 Mar 2025
      Addgene_52963

      DOI: 10.1101/2025.02.19.638911

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    pmc.ncbi.nlm.nih.gov/articles/PMC11888196/
  24. www.sciencedirect.com www.sciencedirect.com
    Simultaneous CRISPR screening and spatial transcriptomics reveal intracellular, intercellular, and functional transcriptional circuits
    1
    1. scibot 13 Mar 2025
      plasmid_52963

      DOI: 10.1016/j.cell.2025.02.012

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    sciencedirect.com/science/article/pii/S0092867425001977
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Divergent Requirements for Glutathione Biosynthesis During Osteoclast Differentiation In Vitro and In Vivo
    1
    1. scibot 11 Mar 2025
      52963

      DOI: 10.3390/antiox14020197

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      DOI:10.3390/antiox14020197 RRID:Addgene_52963
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    pmc.ncbi.nlm.nih.gov/articles/PMC11851466/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Recognition of MR1-antigen complexes by TCR Vγ9Vδ2
    1
    1. scibot 11 Mar 2025
      52963

      DOI: 10.3389/fimmu.2025.1519128

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    pmc.ncbi.nlm.nih.gov/articles/PMC11876030/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Leveraging Circular Polymerization and Extension Cloning (CPEC) Method for Construction of CRISPR Screening Libraries
    2
    1. scibot 11 Mar 2025
      52963

      DOI: 10.21769/BioProtoc.5183

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    2. scibot 11 Mar 2025
      Addgene_52963

      DOI: 10.21769/BioProtoc.5183

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    pmc.ncbi.nlm.nih.gov/articles/PMC11865837/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Histone Demethylase LSD1/ZNF217/CoREST Complex is a Major Restriction Factor of Epstein-Barr Virus Lytic Reactivation
    1
    1. scibot 11 Mar 2025
      52963

      DOI: 10.21203/rs.3.rs-5649616/v1

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    pmc.ncbi.nlm.nih.gov/articles/PMC11774438/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Norovirus co-opts NINJ1 for selective protein secretion
    1
    1. scibot 11 Mar 2025
      52963

      DOI: 10.1126/sciadv.adu7985

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    pmc.ncbi.nlm.nih.gov/articles/PMC11870086/
  30. www.science.org www.science.org
    Epstein-Barr virus–driven cardiolipin synthesis sustains metabolic remodeling during B cell transformation
    1
    1. scibot 11 Mar 2025
      52963

      DOI: 10.1126/sciadv.adr8837

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      DOI:10.1126/sciadv.adr8837 RRID:Addgene_52963
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    science.org/doi/10.1126/sciadv.adr8837
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Insights into the Absence of Lymphoma Despite Fulminant Epstein-Barr Virus Infection in Patients with XIAP Deficiency
    1
    1. scibot 11 Mar 2025
      52963

      DOI: 10.1101/2025.01.17.633616

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      DOI:10.1101/2025.01.17.633616 RRID:Addgene_52963
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    pmc.ncbi.nlm.nih.gov/articles/PMC11761029/
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting the mevalonate pathway potentiates NUAK1 inhibition-induced immunogenic cell death and antitumor immunity
    1
    1. scibot 11 Mar 2025
      52963

      DOI: 10.1016/j.xcrm.2024.101913

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    pmc.ncbi.nlm.nih.gov/articles/PMC11866496/
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CTCF is selectively required for maintaining chromatin accessibility and gene expression in human erythropoiesis
    1
    1. scibot 11 Mar 2025
      Plasmid_52963

      DOI: 10.1186/s13059-025-03510-z

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    pmc.ncbi.nlm.nih.gov/articles/PMC11869676/
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Zinc Alleviates Diabetic Muscle Atrophy via Modulation of the SIRT1/FoxO1 Autophagy Pathway Through GPR39
    1
    1. scibot 11 Mar 2025
      Plasmid_52963

      DOI: 10.1002/jcsm.13771

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    pmc.ncbi.nlm.nih.gov/articles/PMC11873538/
  35. Feb 2025
  36. www.sciencedirect.com www.sciencedirect.com
    Variability in proliferative and migratory defects in Hirschsprung disease-associated RET pathogenic variants
    1
    1. scibot 27 Feb 2025
      Addgene cat. #52963

      DOI: 10.1016/j.ajhg.2025.02.004

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    sciencedirect.com/science/article/pii/S0002929725000515
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Epigenetic priming promotes acquisition of tyrosine kinase inhibitor resistance and oncogene amplification in human lung cancer
    1
    1. scibot 24 Feb 2025
      52963

      DOI: 10.1101/2025.01.26.634826

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    pmc.ncbi.nlm.nih.gov/articles/PMC11838195/
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR screen reveals modifiers of rAAV production including known rAAV infection genes playing an unexpected role in vector production
    1
    1. scibot 23 Feb 2025
      52963

      DOI: 10.1016/j.omtm.2025.101408

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    pmc.ncbi.nlm.nih.gov/articles/PMC11840188/
  39. aacrjournals.org aacrjournals.org
    MR1 gene and protein expression are enhanced by inhibition of the extracellular signal-regulated kinase ERK
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    1. scibot 20 Feb 2025
      RRID:Addgene_52963

      DOI: 10.1158/2326-6066.CIR-24-0110

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    aacrjournals.org/cancerimmunolres/article/12/10/1452/748716/MR1-Gene-and-Protein-Expression-Are-Enhanced-by
  40. www.sciencedirect.com www.sciencedirect.com
    Ergothioneine controls mitochondrial function and exercise performance via direct activation of MPST
    1
    1. scibot 20 Feb 2025
      Plasmid_52963

      DOI: 10.1016/j.cmet.2025.01.024

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    sciencedirect.com/science/article/pii/S1550413125000245
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multidimensional, integrative profiling identifies BCL2L1 methylation as a predictor of MCL1 dependency in pediatric malignancies
    1
    1. scibot 18 Feb 2025
      52963

      DOI: 10.1172/jci.insight.184601

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    pmc.ncbi.nlm.nih.gov/articles/PMC11790018/
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The PRC2.1 subcomplex opposes G1 progression through regulation of CCND1 and CCND2
    1
    1. scibot 18 Feb 2025
      Addgene_52963

      DOI: 10.7554/eLife.97577

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    pmc.ncbi.nlm.nih.gov/articles/PMC11793871/
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of selective SWI/SNF dependencies in enzalutamide-resistant prostate cancer
    1
    1. scibot 18 Feb 2025
      Addgene_52963

      DOI: 10.1038/s42003-024-07413-w

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    pmc.ncbi.nlm.nih.gov/articles/PMC11794516/
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Viral oncogene EBNALP regulates YY1 DNA binding and alters host 3D genome organization
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    1. scibot 16 Feb 2025
      52963

      DOI: 10.1038/s44319-024-00357-6

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    pmc.ncbi.nlm.nih.gov/articles/PMC11811279/
  45. 52.53.155.43 52.53.155.43
    PDF-html.html
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    1. scibot 14 Feb 2025
      RRID:Addgene_52963

      DOI: 10.1158/2643-3230.bcd-24-0140

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    52.53.155.43/b6e42261d11f7c0ae043c89c64cba240f59a1523/PDF-html.html
  46. Jan 2025
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NAC regulates metabolism and cell fate in intestinal stem cells
    1
    1. scibot 27 Jan 2025
      LentiGuide-Puro

      DOI: 10.1126/sciadv.adn9750

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  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Knockout or inhibition of DHPS suppresses ovarian tumor growth and metastasis by attenuating the TGFβ pathway
    1
    1. scibot 27 Jan 2025
      52963

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    pmc.ncbi.nlm.nih.gov/articles/PMC11704301/
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Hira complex regulates Gli3R-dependent transcription in Hedgehog signaling and medulloblastoma cell growth and migration
    1
    1. scibot 27 Jan 2025
      52963

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    pmc.ncbi.nlm.nih.gov/articles/PMC11697252/
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular basis for shifted receptor recognition by an encephalitic arbovirus
    1
    1. scibot 27 Jan 2025
      Addgene_52963

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  51. www.nature.com www.nature.com
    Targeting mitochondrial RNAs enhances the efficacy of the DNA-demethylating agents
    1
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      Addgene_52963

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  52. Dec 2024
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Gliocidin is a nicotinamide-mimetic prodrug that targets glioblastoma
    1
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      52963

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  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Base editing of Ptbp1 in neurons alleviates symptoms in a mouse model of Parkinson’s disease
    1
    1. scibot 27 Dec 2024
      Addgene_52963

      DOI: 10.7554/eLife.97180

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    pmc.ncbi.nlm.nih.gov/articles/PMC11666242/
  55. www.sciencedirect.com www.sciencedirect.com
    TurboCas: A method for locus-specific labeling of genomic regions and isolating their associated protein interactome
    2
    1. scibot 24 Dec 2024
      AddgeneCat# 52963

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      Addgene_52963

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    sciencedirect.com/science/article/pii/S1097276524009122
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Control of cell proliferation by memories of mitosis
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    1. scibot 11 Dec 2024
      RRID:Addgene_52963

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    pmc.ncbi.nlm.nih.gov/articles/PMC11621110/
  57. Nov 2024
  58. www.biorxiv.org www.biorxiv.org
    Endocrine persistence in ER+ breast cancer is accompanied by metabolic vulnerability in oxidative phosphorylation
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    1. scibot 20 Nov 2024
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    biorxiv.org/content/10.1101/2024.09.26.615177v1
  59. www.sciencedirect.com www.sciencedirect.com
    Profound synthetic lethality between SMARCAL1 and FANCM
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    sciencedirect.com/science/article/pii/S1097276524008566
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chromatin protein complexes involved in gene repression in lamina-associated domains
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      Addgene_52963

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    pmc.ncbi.nlm.nih.gov/articles/PMC11535540/
  61. Sep 2024
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR screenings identified SMCHD1 as a host-restricting factor for AAV transduction
    1
    1. scibot 29 Sep 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11257396/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The histone methyltransferase KMT2D maintains cellular glucocorticoid responsiveness by shielding the glucocorticoid receptor from degradation
    1
    1. scibot 29 Sep 2024
      52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC11350265/
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phospholipid scrambling induced by an ion channel/metabolite transporter complex
    1
    1. scibot 29 Sep 2024
      52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC11366033/
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multi-omic lineage tracing predicts the transcriptional, epigenetic and genetic determinants of cancer evolution
    1
    1. scibot 29 Sep 2024
      52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC11366763/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MYBL2 Drives Prostate Cancer Plasticity: Inhibiting Its Transcriptional Target CDK2 for RB1-Deficient Neuroendocrine Prostate Cancer
    1
    1. scibot 29 Sep 2024
      52963

      DOI: 10.1158/2767-9764.CRC-24-0069

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    ncbi.nlm.nih.gov/pmc/articles/PMC11368174/
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The V-ATPase complex component RNAseK is required for lysosomal hydrolase delivery and autophagosome degradation
    1
    1. scibot 29 Sep 2024
      plasmid_52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC11374810/
  68. www.biorxiv.org www.biorxiv.org
    Clustered macrophages cooperate to eliminate tumors via coordinated intrudopodia
    1
    1. scibot 28 Sep 2024
      RRID:Addgene_52963

      DOI: 10.1101/2024.09.19.613918

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    biorxiv.org/content/10.1101/2024.09.19.613918v1
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protocol for in vivo CRISPR screening targeting murine testicular cells
    1
    1. scibot 27 Sep 2024
      52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC11416641/
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EspH utilizes phosphoinositide and Rab binding domains to interact with plasma membrane infection sites and Rab GTPases*
    1
    1. scibot 27 Sep 2024
      (https://media.addgene.org

      DOI: 10.1080/19490976.2024.2400575

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    ncbi.nlm.nih.gov/pmc/articles/PMC11421376/
  71. www.sciencedirect.com www.sciencedirect.com
    Saturation mutagenesis-reinforced functional assays for disease-related genes
    1
    1. scibot 27 Sep 2024
      Plasmid_52963

      DOI: 10.1016/j.cell.2024.08.047

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    sciencedirect.com/science/article/pii/S0092867424009760
  72. www.biorxiv.org www.biorxiv.org
    Cytotoxicity of Activator Expression in CRISPR-based Transcriptional Activation Systems
    1
    1. scibot 27 Sep 2024
      plasmid_52963

      DOI: 10.1101/2024.09.23.614524

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    biorxiv.org/content/10.1101/2024.09.23.614524v1
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atrial fibrillation variant-to-gene prioritization through cross-ancestry eQTL and single-nucleus multiomic analyses
    1
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      Addgene_52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC11388022/
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Host cell CRISPR genomics and modelling reveal shared metabolic vulnerabilities in the intracellular development of Plasmodium falciparum and related hemoparasites
    1
    1. scibot 26 Sep 2024
      52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC11271486/
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhancer activation from transposable elements in extrachromosomal DNA
    1
    1. scibot 26 Sep 2024
      Plasmid_52963

      DOI: 10.1101/2024.09.04.611262

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    ncbi.nlm.nih.gov/pmc/articles/PMC11398463/
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of resistance mechanisms to small-molecule inhibition of TEAD-regulated transcription
    1
    1. scibot 26 Sep 2024
      Addgene_52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC11387499/
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stem cells tightly regulate dead cell clearance to maintain tissue fitness
    1
    1. scibot 25 Sep 2024
      Addgene_52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC11390485/
  78. www.sciencedirect.com www.sciencedirect.com
    Protein UFMylation regulates early events during ribosomal DNA-damage response
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    1. scibot 17 Sep 2024
      Addgene_52963

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    sciencedirect.com/science/article/pii/S2211124724010891
  79. www.sciencedirect.com www.sciencedirect.com
    MIG6 loss increased RET inhibitor tolerant persister cells in RET-rearranged non-small cell lung cancer
    1
    1. scibot 06 Sep 2024
      #52963, Addgene

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    sciencedirect.com/science/article/pii/S0304383524006153
  80. Aug 2024
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas9 screening develops an epigenetic and transcriptional gene signature for risk stratification and target prediction in neuroblastoma
    1
    1. scibot 26 Aug 2024
      52963

      DOI: 10.3389/fcell.2024.1433008

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    ncbi.nlm.nih.gov/pmc/articles/PMC11338898/
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Specific multivalent molecules boost CRISPR-mediated transcriptional activation
    1
    1. scibot 26 Aug 2024
      52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC11341856/
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Shifts in receptors during submergence of an encephalitic arbovirus
    1
    1. scibot 26 Aug 2024
      Addgene_52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC11324528/
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR screening uncovers a long-range enhancer for ONECUT1 in pancreatic differentiation and links a diabetes risk variant
    1
    1. scibot 23 Aug 2024
      RRID:Addgene_52963

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  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Fanconi anemia core complex promotes CtIP-dependent end resection to drive homologous recombination at DNA double-strand breaks
    1
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      Addgene_52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC11329772/
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis for VLDLR recognition by eastern equine encephalitis virus
    1
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      Addgene_52963

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  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The interferon γ pathway enhances pluripotency and X-chromosome reactivation in iPSC reprogramming
    1
    1. scibot 21 Aug 2024
      RRID:Addgene_52963

      DOI: 10.1126/sciadv.adj8862

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  88. www.biorxiv.org www.biorxiv.org
    An enhanced Eco1 retron editor enables precision genome engineering in human cells from a single-copy integrated lentivirus
    1
    1. scibot 20 Aug 2024
      Addgene_52963

      DOI: 10.1101/2024.08.05.606586

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    biorxiv.org/content/10.1101/2024.08.05.606586v2
  89. www.cell.com www.cell.com
    Calcineurin is an adaptor required for assembly of the TCR signaling complex
    1
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      RRID:Addgene_52963

      DOI: 10.1016/j.celrep.2024.114568

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    cell.com/cell-reports/fulltext/S2211-1247(24)00897-0
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers
    1
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      52963

      DOI: 10.1126/science.adk0775

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  91. www.cell.com www.cell.com
    SETDB1 suppresses NK cell-mediated immunosurveillance in acute myeloid leukemia with granulo-monocytic differentiation
    1
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      RRID:Addgene_52963

      DOI: 10.1016/j.celrep.2024.114536

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    cell.com/cell-reports/fulltext/S2211-1247(24)00865-9
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide Cas9-mediated screening of essential non-coding regulatory elements via libraries of paired single-guide RNAs
    1
    1. scibot 17 Aug 2024
      52963

      DOI: 10.1038/s41551-024-01204-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC11310080/
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Library‐Assisted Evolution in Eukaryotic Cells Yield Adenine Base Editors with Enhanced Editing Specificity
    1
    1. scibot 17 Aug 2024
      52963

      DOI: 10.1002/advs.202309004

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  94. www.nature.com www.nature.com
    3D genomic analysis reveals novel enhancer-hijacking caused by complex structural alterations that drive oncogene overexpression
    1
    1. scibot 13 Aug 2024
      52963

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  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A genome-wide CRISPR/Cas9 knockout screen identifies TMEM239 as an important host factor in facilitating African swine fever virus entry into early endosomes
    1
    1. scibot 13 Aug 2024
      52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC11288436/
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Serine/arginine-rich splicing factor 7 promotes the type I interferon response by activating Irf7 transcription
    1
    1. scibot 13 Aug 2024
      52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC11056844/
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    iNOS is necessary for GBP-mediated T. gondii clearance in murine macrophages via vacuole nitration and intravacuolar network collapse
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    1. scibot 13 Aug 2024
      52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC10973475/
  98. Jul 2024
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Hippo pathway kinases LATS1 and 2 attenuate cellular responses to heavy metals through phosphorylating MTF1
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    1. scibot 27 Jul 2024
      plasmid_52963

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  100. www.embopress.org www.embopress.org
    DUSP6 inhibition overcomes neuregulin/HER3-driven therapy tolerance in HER2+ breast cancer
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      plasmid_52963

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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DUSP6 inhibition overcomes neuregulin/HER3-driven therapy tolerance in HER2+ breast cancer
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    1. scibot 18 Jul 2024
      plasmid_52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC11251193/
  102. www.biorxiv.org www.biorxiv.org
    Acute BRCAness Induction and AR Signaling Blockage through CDK12/7/9 Degradation Enhances PARP Inhibitor Sensitivity in Prostate Cancer
    1
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      RRID:Addgene_52963

      DOI: 10.1101/2024.07.09.602803

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    biorxiv.org/content/10.1101/2024.07.09.602803v1
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DUSP4 enhances therapeutic sensitivity in HER2-positive breast cancer by inhibiting the G6PD pathway and ROS metabolism by interacting with ALDOB
    1
    1. scibot 01 Jul 2024
      lentiGuide-Puro

      DOI: 10.1016/j.tranon.2024.102016

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    ncbi.nlm.nih.gov/pmc/articles/PMC11214528/
  104. Jun 2024
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumour-derived Extracellular Vesicle and Particle Reprogramming of Interstitial Macrophages in the Lung Pre-Metastatic Niche Enhances Vascular Permeability and Metastatic Potential
    1
    1. scibot 21 Jun 2024
      52963

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  106. www.sciencedirect.com www.sciencedirect.com
    An enhancer RNA recruits KMT2A to regulate transcription of Myb
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    1. scibot 21 Jun 2024
      plasmid_52963

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    sciencedirect.com/science/article/pii/S221112472400706X
  107. www.sciencedirect.com www.sciencedirect.com
    SpRY-mediated screens facilitate functional dissection of non-coding sequences at single-base resolution
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    1. scibot 21 Jun 2024
      Addgene_52963

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    sciencedirect.com/science/article/pii/S2666979X24001678
  108. www.sciencedirect.com www.sciencedirect.com
    STING orchestrates the neuronal inflammatory stress response in multiple sclerosis
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    1. scibot 21 Jun 2024
      plasmid_52963

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  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The CTLH Ubiquitin Ligase Substrates ZMYND19 and MKLN1 Negatively Regulate mTORC1 at the Lysosomal Membrane
    1
    1. scibot 21 Jun 2024
      plasmid_52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC11092817/
  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The balance between antiviral and antibacterial responses during M. tuberculosis infection is regulated by the ubiquitin ligase CBL
    1
    1. scibot 21 Jun 2024
      Plasmid_52963

      DOI: 10.1101/2024.05.15.594178

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  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multi-omic Analysis of Human B-cell Activation Reveals a Key Lysosomal BCAT1 Role in mTOR Hyperactivation by B-cell receptor and TLR9
    1
    1. scibot 21 Jun 2024
      plasmid_52963

      DOI: 10.21203/rs.3.rs-4413958/v1

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  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation
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    1. scibot 20 Jun 2024
      Addgene_52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC11182672/
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The integrin CD11b inhibits MSU-induced NLRP3 inflammasome activation in macrophages and protects mice against MSU-induced joint inflammation
    1
    1. scibot 15 Jun 2024
      52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC11165854/
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BCMA/CD47-directed universal CAR-T cells exhibit excellent antitumor activity in multiple myeloma
    1
    1. scibot 07 Jun 2024
      52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC11112799/
  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A synthetic lethal dependency on casein kinase 2 in response to replication-perturbing therapeutics in RB1-deficient cancer cells
    1
    1. scibot 07 Jun 2024
      52963

      DOI: 10.1126/sciadv.adj1564

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    ncbi.nlm.nih.gov/pmc/articles/PMC11114247/
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large-scale mutational analysis identifies UNC93B1 variants that drive TLR-mediated autoimmunity in mice and humans
    1
    1. scibot 07 Jun 2024
      Plasmid_52963

      DOI: 10.1084/jem.20232005

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    ncbi.nlm.nih.gov/pmc/articles/PMC11116816/
  117. www.sciencedirect.com www.sciencedirect.com
    ΔNp63-restricted viral mimicry response impedes cancer cell viability and remodels tumor microenvironment in esophageal squamous cell carcinoma
    1
    1. scibot 04 Jun 2024
      plasmid_52963

      DOI: 10.1016/j.canlet.2024.216999

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    sciencedirect.com/science/article/pii/S0304383524003938
  118. May 2024
  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The nucleic acid binding protein SFPQ represses EBV lytic reactivation by promoting histone H1 expression
    1
    1. scibot 19 May 2024
      Addgene_52963

      DOI: 10.1038/s41467-024-48333-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC11099029/
  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Germinal center cytokine driven epigenetic control of Epstein-Barr virus latency gene expression
    1
    1. scibot 12 May 2024
      plasmid_52963

      DOI: 10.1371/journal.ppat.1011939

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    ncbi.nlm.nih.gov/pmc/articles/PMC11081508/
  121. www.sciencedirect.com www.sciencedirect.com
    NRP1 is a receptor for mammalian orthoreovirus engaged by distinct capsid subunits
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    1. scibot 10 May 2024
      RRID:Addgene_52963

      DOI: 10.1016/j.chom.2024.04.014

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    sciencedirect.com/science/article/pii/S1931312824001343
  122. www.sciencedirect.com www.sciencedirect.com
    Identification of WNK1 as a therapeutic target to suppress IgH/MYC expression in multiple myeloma
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    1. scibot 09 May 2024
      plasmid_52963

      DOI: 10.1016/j.celrep.2024.114211

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    sciencedirect.com/science/article/pii/S2211124724005394
  123. www.sciencedirect.com www.sciencedirect.com
    An ATP13A1-assisted topogenesis pathway for folding multi-spanning membrane proteins
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    1. scibot 09 May 2024
      Addgene_52963

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    sciencedirect.com/science/article/pii/S1097276524003253
  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Germline cis variant determines epigenetic regulation of the anti-cancer drug metabolism gene dihydropyrimidine dehydrogenase (DPYD)
    2
    1. scibot 05 May 2024
      Addgene_52963

      DOI: 10.7554/eLife.94075

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      DOI: 10.7554/eLife.94075

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    ncbi.nlm.nih.gov/pmc/articles/PMC11060711/
  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modulation of the microhomology-mediated end joining pathway suppresses large deletions and enhances homology-directed repair following CRISPR-Cas9-induced DNA breaks
    1
    1. scibot 05 May 2024
      52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC11059712/
  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NFATC2IP is a mediator of SUMO-dependent genome integrity
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    1. scibot 05 May 2024
      52963

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  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epstein-Barr-Virus-Driven Cardiolipin Synthesis Sustains Metabolic Remodeling During B-cell Lymphomagenesis
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    1. scibot 05 May 2024
      plasmid_52963

      DOI: 10.21203/rs.3.rs-4013392/v1

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  128. elifesciences.org elifesciences.org
    Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
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    1. scibot 03 May 2024
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      DOI: 10.7554/eLife.90683

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  129. www.biorxiv.org www.biorxiv.org
    Epstein–Barr Virus BALF0/1 Subverts the Caveolin and ERAD Pathways to Target B-cell Receptor Complexes for Degradation
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    1. scibot 02 May 2024
      RRID:Addgene_52963

      DOI: 10.1101/2024.01.04.574276

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  130. www.sciencedirect.com www.sciencedirect.com
    Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease
    2
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      RRID:Addgene_52963

      DOI: 10.1016/j.stem.2024.04.002

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    sciencedirect.com/science/article/pii/S1934590924001292
  131. Apr 2024
  132. www.sciencedirect.com www.sciencedirect.com
    GPATCH8 modulates mutant SF3B1 mis-splicing and pathogenicity in hematologic malignancies
    1
    1. scibot 30 Apr 2024
      Addgene: 52963

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  133. www.sciencedirect.com www.sciencedirect.com
    Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB
    2
    1. scibot 26 Apr 2024
      Addgene, Cat# 52963

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      plasmid_52963

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    sciencedirect.com/science/article/pii/S0092867424003131
  134. www.sciencedirect.com www.sciencedirect.com
    IGSF8 is an innate immune checkpoint and cancer immunotherapy target
    1
    1. scibot 24 Apr 2024
      AddgeneCat# 52963

      DOI: 10.1016/j.cell.2024.03.039

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    sciencedirect.com/science/article/pii/S0092867424003556
  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deletion of the TMEM30A gene enables leukemic cell evasion of NK cell cytotoxicity
    1
    1. scibot 23 Apr 2024
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      DOI: 10.1073/pnas.2316447121

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    ncbi.nlm.nih.gov/pmc/articles/PMC11009675/
  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-scale pan-cancer interrogation of lncRNA dependencies using CasRx
    1
    1. scibot 23 Apr 2024
      52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC11009108/
  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRPF19 mRNA Encodes a Small Open Reading Frame That Is Important for Viability of Human Cells
    1
    1. scibot 23 Apr 2024
      52963

      DOI: 10.1134/S1607672923700722

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    ncbi.nlm.nih.gov/pmc/articles/PMC11021245/
  138. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Frequent loss of FAM126A expression in colorectal cancer results in selective FAM126B dependency
    1
    1. scibot 23 Apr 2024
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      DOI: 10.1016/j.isci.2024.109646

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    ncbi.nlm.nih.gov/pmc/articles/PMC11025007/
  139. www.sciencedirect.com www.sciencedirect.com
    Functional genomics identifies N-acetyllactosamine extension of complex N-glycans as a mechanism to evade lysis by natural killer cells
    1
    1. scibot 16 Apr 2024
      plasmid_52963

      DOI: 10.1016/j.celrep.2024.114105

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    sciencedirect.com/science/article/pii/S2211124724004339
  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
    1
    1. scibot 14 Apr 2024
      52963

      DOI: 10.1038/s41586-023-06688-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC11000523/
  141. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Thymidine nucleotide metabolism controls human telomere length
    1
    1. scibot 14 Apr 2024
      52963

      DOI: 10.1038/s41588-023-01339-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC11000509/
  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The PRC2.1 Subcomplex Opposes G1 Progression through Regulation of CCND1 and CCND2
    1
    1. scibot 14 Apr 2024
      Addgene_52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC10983909/
  143. www.sciencedirect.com www.sciencedirect.com
    BLM helicase unwinds lagging strand substrates to assemble the ALT telomere damage response
    2
    1. scibot 09 Apr 2024
      Addgene52963

      DOI: 10.1016/j.molcel.2024.03.011

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      plasmid_52963

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    sciencedirect.com/science/article/pii/S1097276524002211
  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting of vulnerabilities of drug-tolerant persisters identified through functional genetics delays tumor relapse
    1
    1. scibot 03 Apr 2024
      AddgeneCat# 52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC10983104/
  145. www.sciencedirect.com www.sciencedirect.com
    The SPATA5-SPATA5L1 ATPase complex directs replisome proteostasis to ensure genome integrity
    2
    1. scibot 02 Apr 2024
      Plasmid_52963

      DOI: 10.1016/j.cell.2024.03.002

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      Plasmid_52963

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    sciencedirect.com/science/article/pii/S0092867424002502
  146. Mar 2024
  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9 targeting of passenger single nucleotide variants in haploinsufficient or essential genes expands cancer therapy prospects
    1
    1. scibot 31 Mar 2024
      52,963

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    ncbi.nlm.nih.gov/pmc/articles/PMC10978915/
  148. www.sciencedirect.com www.sciencedirect.com
    Pooled CRISPR screening of high-content cellular phenotypes using ghost cytometry
    1
    1. scibot 29 Mar 2024
      Addgene52963

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    sciencedirect.com/science/article/pii/S2667237524000626
  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome‐wide loss‐of‐function genetic screen identifies INSIG2 as the vulnerability of hepatitis B virus‐integrated hepatoma cells
    1
    1. scibot 17 Mar 2024
      52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC10920982/
  150. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Repeat DNA methylation is modulated by adherens junction signaling
    1
    1. scibot 17 Mar 2024
      Addgene_52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC10920906/
  151. www.sciencedirect.com www.sciencedirect.com
    In vivo CRISPR screening directly targeting testicular cells
    1
    1. scibot 06 Mar 2024
      Addgene: #52963

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    sciencedirect.com/science/article/pii/S2666979X24000375
  152. Feb 2024
  153. www.sciencedirect.com www.sciencedirect.com
    A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis
    1
    1. scibot 29 Feb 2024
      AddgeneCat#52963

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    sciencedirect.com/science/article/pii/S1097276524000984
  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The exocyst complex and intracellular vesicles mediate soluble protein trafficking to the primary cilium
    1
    1. scibot 29 Feb 2024
      pLentiGuide-puro

      DOI: 10.1038/s42003-024-05817-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC10879184/
  155. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deep learning models incorporating endogenous factors beyond DNA sequences improve the prediction accuracy of base editing outcomes
    1
    1. scibot 29 Feb 2024
      Plasmid_52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC10879117/
  156. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    3D genomic analysis reveals novel enhancer-hijacking caused by complex structural alterations that drive oncogene overexpression
    1
    1. scibot 21 Feb 2024
      52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC10849656/
  157. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multifaceted roles for STAT3 in gammaherpesvirus latency revealed through in vivo B cell knockout models
    1
    1. scibot 21 Feb 2024
      Addgene_52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC10870824/
  158. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons
    1
    1. scibot 15 Feb 2024
      plasmid_52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC10857481/
  159. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cell cycle arrest induces lipid droplet formation and confers ferroptosis resistance
    1
    1. scibot 13 Feb 2024
      52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC10761718/
  160. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aneuploid embryonic stem cells drive teratoma metastasis
    1
    1. scibot 13 Feb 2024
      52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC10844504/
  161. journals.plos.org journals.plos.org
    CRISPR screen for protein inclusion formation uncovers a role for SRRD in the regulation of intermediate filament dynamics and aggresome assembly
    1
    1. scibot 09 Feb 2024
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    journals.plos.org/plosgenetics/article
  162. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated multi-omics analyses identify anti-viral host factors and pathways controlling SARS-CoV-2 infection
    1
    1. scibot 08 Feb 2024
      52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC10761986/
  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Detection of senescence using machine learning algorithms based on nuclear features
    1
    1. scibot 08 Feb 2024
      52963

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    ncbi.nlm.nih.gov/pmc/articles/PMC10838307/
  164. www.sciencedirect.com www.sciencedirect.com
    Alternative polyadenylation determines the functional landscape of inverted Alu repeats
    1
    1. scibot 06 Feb 2024
      AddgeneCat# 52963

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    sciencedirect.com/science/article/pii/S1097276524000091
  165. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA-binding protein RBM5 plays an essential role in acute myeloid leukemia by activating the oncogenic protein HOXA9
    1
    1. scibot 06 Feb 2024
      52,963

      DOI: 10.1186/s13059-023-03149-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC10785552/
  166. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Micronucleus is not a potent inducer of the cGAS/STING pathway
    1
    1. scibot 05 Feb 2024
      52963

      DOI: 10.26508/lsa.202302424

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    ncbi.nlm.nih.gov/pmc/articles/PMC10837050/
  167. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Germinal Center Cytokines Driven Epigenetic Control of Epstein-Barr Virus Latency Gene Expression
    1
    1. scibot 05 Feb 2024
      plasmid_52963

      DOI: 10.1101/2024.01.02.573986

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    ncbi.nlm.nih.gov/pmc/articles/PMC10802360/
  168. www.sciencedirect.com www.sciencedirect.com
    Two-step evolution of HIV-1 budding system leading to pandemic in the human population
    1
    1. scibot 02 Feb 2024
      Addgene_52963

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    sciencedirect.com/science/article/pii/S2211124724000251
  169. Jan 2024
  170. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epstein-Barr virus induces germinal center light zone chromatin architecture and promotes survival through enhancer looping at the BCL2A1 locus
    1
    1. scibot 20 Jan 2024
      RRID:Addgene_52963

      DOI: 10.1128/mbio.02444-23

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    ncbi.nlm.nih.gov/pmc/articles/PMC10790771/
  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epstein-Barr virus miR-BARTs 7 and 9 modulate viral cycle, cell proliferation, and proteomic profiles in Burkitt lymphoma
    1
    1. scibot 11 Jan 2024
      RRID:Addgene_52963

      DOI: 10.1016/j.tvr.2023.200276

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    ncbi.nlm.nih.gov/pmc/articles/PMC11000110/
  172. Dec 2023
  173. www.sciencedirect.com www.sciencedirect.com
    Single-cell functional genomics reveals determinants of sensitivity and resistance to natural killer cells in blood cancers
    1
    1. scibot 17 Dec 2023
      RRID:Addgene_52963

      DOI: 10.1016/j.immuni.2023.11.008

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    sciencedirect.com/science/article/pii/S1074761323004909
  174. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson’s disease-linked LRRK2 kinase
    1
    1. scibot 15 Dec 2023
      RRID:Addgene_52963

      DOI: 10.7554/eLife.87098

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    ncbi.nlm.nih.gov/pmc/articles/PMC10708890/
  175. journals.asm.org journals.asm.org
    Epstein-Barr virus induces germinal center light zone chromatin architecture and promotes survival through enhancer looping at the BCL2A1 locus
    1
    1. scibot 14 Dec 2023
      RRID:Addgene_52963

      DOI: 10.1128/mbio.02444-23

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    journals.asm.org/doi/10.1128/mbio.02444-23
  176. Nov 2023
  177. www.sciencedirect.com www.sciencedirect.com
    Aurora A kinase inhibition induces accumulation of SCLC tumor cells in mitosis with restored interferon signaling to increase response to PD-L1
    1
    1. scibot 22 Nov 2023
      Addgene_52963

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    sciencedirect.com/science/article/pii/S2666379123004767
  178. biosignaling.biomedcentral.com biosignaling.biomedcentral.com
    Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival
    1
    1. scibot 18 Nov 2023
      RRID:Addgene_52963

      DOI: 10.1186/s12964-023-01335-6

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    biosignaling.biomedcentral.com/articles/10.1186/s12964-023-01335-6
  179. www.sciencedirect.com www.sciencedirect.com
    HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation
    1
    1. scibot 17 Nov 2023
      RRID:Addgene_52963

      DOI: 10.1016/j.celrep.2023.113352

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    sciencedirect.com/science/article/pii/S2211124723013645
  180. Oct 2023
  181. www.biorxiv.org www.biorxiv.org
    Genome-wide CRISPR/Cas9 screen identifies MAT2A as a critical host factor for BK Polyomavirus
    1
    1. scibot 27 Oct 2023
      RRID:Addgene_52963

      DOI: 10.1101/2023.10.20.563362

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    biorxiv.org/content/10.1101/2023.10.20.563362v1
  182. www.cell.com www.cell.com
    PUF60 promotes cell cycle and lung cancer progression by regulating alternative splicing of CDC25C
    1
    1. scibot 06 Oct 2023
      RRID:Addgene_52963

      DOI: 10.1016/j.celrep.2023.113041

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    cell.com/cell-reports/fulltext/S2211-1247(23)01052-5
  183. Sep 2023
  184. www.nature.com www.nature.com
    CRISPR prime editing for unconstrained correction of oncogenic KRAS variants
    1
    1. scibot 20 Sep 2023
      52963

      DOI: 10.1038/s42003-023-05052-1

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    nature.com/articles/s42003-023-05052-1
  185. www.sciencedirect.com www.sciencedirect.com
    Combined CRISPRi and proteomics screening reveal a cohesin-CTCF-bound allele contributing to increased expression of RUVBL1 and prostate cancer progression
    1
    1. scibot 19 Sep 2023
      RRID:Addgene_52963

      DOI: 10.1016/j.ajhg.2023.07.003

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    sciencedirect.com/science/article/pii/S0002929723002434
  186. www.sciencedirect.com www.sciencedirect.com
    Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment
    1
    1. scibot 16 Sep 2023
      RRID:Addgene_52963

      DOI: 10.1016/j.celrep.2023.113098

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    sciencedirect.com/science/article/pii/S2211124723011099
  187. Aug 2023
  188. www.biorxiv.org www.biorxiv.org
    Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
    1
    1. scibot 16 Aug 2023
      plasmid_52963

      DOI: 10.1101/2023.07.26.550648

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    biorxiv.org/content/10.1101/2023.07.26.550648v2
  189. www.biorxiv.org www.biorxiv.org
    The Interferon γ Pathway Enhances Pluripotency and X-Chromosome Reactivation in iPSC reprogramming
    2
    1. scibot 12 Aug 2023
      plasmids #52963

      DOI: 10.1101/2023.07.31.551297

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      RRID:Addgene_52963

      DOI: 10.1101/2023.07.31.551297

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    biorxiv.org/content/10.1101/2023.07.31.551297v3
  190. Jul 2023
  191. 52.53.155.43 52.53.155.43
    Parallel genome-scale CRISPR screens distinguish pluripotency and self-renewal
    1
    1. scibot 15 Jul 2023
      52963

      DOI: 10.1101/2023.05.03.539283

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    52.53.155.43/8add9715cb6d409825df8305aa589d745e83436f/2023.05.03.539283.full-html.html
  192. Jun 2023
  193. www.sciencedirect.com www.sciencedirect.com
    Generation of Myoglobin (MB)-Knockout human embryonic stem cell (hESC) line (KAIMRCe002- A-1S) using CRISPR/Cas9 technology
    1
    1. scibot 28 Jun 2023
      Addgene_52963

      DOI: 10.1016/j.scr.2023.103158

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    sciencedirect.com/science/article/pii/S1873506123001447
  194. www.sciencedirect.com www.sciencedirect.com
    An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets
    1
    1. scibot 23 Jun 2023
      RRID: Addgene_52963

      DOI: 10.1016/j.ccell.2023.06.001

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    sciencedirect.com/science/article/pii/S1535610823002088
  195. www.biorxiv.org www.biorxiv.org
    Transcriptional landscape of DTP-DTEP transition reveals DUSP6 as a driver of HER2 inhibitor tolerance via Neuregulin/HER3 axis
    1
    1. scibot 22 Jun 2023
      plasmid_52963

      DOI: 10.1101/2023.06.14.544493

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    biorxiv.org/content/10.1101/2023.06.14.544493v1
  196. www.sciencedirect.com www.sciencedirect.com
    An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylation
    1
    1. scibot 16 Jun 2023
      RRID:Addgene_52963

      DOI: 10.1016/j.molcel.2023.05.018

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    sciencedirect.com/science/article/pii/S109727652300374X
  197. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IKKβ primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network
    1
    1. scibot 14 Jun 2023
      RRID:Addgene_52963

      DOI: 10.1016/j.immuni.2022.10.021

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    ncbi.nlm.nih.gov/pmc/articles/PMC7614333/
  198. aacrjournals.org aacrjournals.org
    (R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers
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    1. scibot 10 Jun 2023
      RRID:Addgene_52963

      DOI: 10.1158/2159-8290.CD-22-0825

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    aacrjournals.org/cancerdiscovery/article/13/6/1478/726967/R-2-Hydroxyglutarate-Inhibits-KDM5-Histone-Lysine
  199. aacrjournals.org aacrjournals.org
    RBM10 loss promotes EGFR-driven lung cancer and confers sensitivity to spliceosome inhibition
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    1. scibot 03 Jun 2023
      RRID:Addgene_52963

      DOI: 10.1158/0008-5472.CAN-22-1549

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    aacrjournals.org/cancerres/article/83/9/1490/726058/RBM10-Loss-Promotes-EGFR-Driven-Lung-Cancer-and
  200. www.biorxiv.org www.biorxiv.org
    Stem cells tightly regulate dead cell clearance to maintain tissue fitness
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    1. scibot 01 Jun 2023
      Addgene_52963

      DOI: 10.1101/2023.05.22.541773

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    biorxiv.org/content/10.1101/2023.05.22.541773v1
  201. May 2023
  202. www.biorxiv.org www.biorxiv.org
    Epstein-Barr virus miR-BARTs 7 and 9 modulate viral cycle, cell proliferation and proteomic profiles in Burkitt lymphoma
    1
    1. scibot 25 May 2023
      RRID:Addgene_52963

      DOI: 10.1101/2023.05.19.538556

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    biorxiv.org/content/10.1101/2023.05.19.538556v1
  203. www.biorxiv.org www.biorxiv.org
    Group comparison based on genetic information reveals lineage-specific therapeutic vulnerabilities in acute myeloid leukemia
    1
    1. scibot 25 May 2023
      RRID:Addgene_52963

      DOI: 10.1101/2023.05.18.541265

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    biorxiv.org/content/10.1101/2023.05.18.541265v1
  204. www.sciencedirect.com www.sciencedirect.com
    Multi-omics analysis reveals distinct non-reversion mechanisms of PARPi resistance in BRCA1- versus BRCA2-deficient mammary tumors
    1
    1. scibot 25 May 2023
      RRID:Addgene_52963

      DOI: 10.1016/j.celrep.2023.112538

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    sciencedirect.com/science/article/pii/S2211124723005491
  205. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis
    1
    1. scibot 25 May 2023
      Addgene_52963

      DOI: 10.1101/gad.328336.119

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    ncbi.nlm.nih.gov/pmc/articles/PMC6942053/
  206. Apr 2023
  207. www.sciencedirect.com www.sciencedirect.com
    Proteomic discovery of chemical probes that perturb protein complexes in human cells
    1
    1. scibot 21 Apr 2023
      Addgene_52963

      DOI: 10.1016/j.molcel.2023.03.026

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    sciencedirect.com/science/article/pii/S1097276523002393
  208. Mar 2023
  209. www.nature.com www.nature.com
    The protective role of conjunctival goblet cell mucin sialylation
    1
    1. scibot 18 Mar 2023
      RRID:Addgene_52963

      DOI: 10.1038/s41467-023-37101-y

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    nature.com/articles/s41467-023-37101-y
  210. Feb 2023
  211. www.embopress.org www.embopress.org
    Immune surveillance of brain metastatic cancer cells is mediated by IFITM1
    1
    1. scibot 18 Feb 2023
      RRID:Addgene_52963

      DOI: 10.15252/embj.2022111112

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    embopress.org/doi/10.15252/embj.2022111112
  212. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs
    1
    1. scibot 15 Feb 2023
      Addgene_52963

      DOI: 10.1371/journal.pbio.3001967

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    ncbi.nlm.nih.gov/pmc/articles/PMC9910744/
  213. Jan 2023
  214. www.sciencedirect.com www.sciencedirect.com
    Metabolic adaptation supports enhanced macrophage efferocytosis in limited-oxygen environments
    1
    1. scibot 28 Jan 2023
      plasmid_52963

      DOI: 10.1016/j.cmet.2022.12.005

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    sciencedirect.com/science/article/pii/S1550413122005423
  215. www.sciencedirect.com www.sciencedirect.com
    Protein folding stress potentiates NLRP1 and CARD8 inflammasome activation
    1
    1. scibot 25 Jan 2023
      Addgene_52963

      DOI: 10.1016/j.celrep.2022.111965

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    sciencedirect.com/science/article/pii/S2211124722018691
  216. www.sciencedirect.com www.sciencedirect.com
    The NLRP1 and CARD8 inflammasomes detect reductive stress
    1
    1. scibot 19 Jan 2023
      Addgene_52963

      DOI: 10.1016/j.celrep.2022.111966

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    sciencedirect.com/science/article/pii/S2211124722018708
  217. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of β2 microglobulin, the product of B2M gene, as a Host Factor for Vaccinia Virus Infection by Genome-Wide CRISPR genetic screens
    1
    1. scibot 11 Jan 2023
      RRID:Addgene_52963

      DOI: 10.1371/journal.ppat.1010800

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    ncbi.nlm.nih.gov/pmc/articles/PMC9829182/
  218. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Deletion of Bak1 alleviates microglial necroptosis and neuroinflammation after experimental subarachnoid hemorrhage
    1
    1. scibot 10 Jan 2023
      RRID:Addgene_52963

      DOI: 10.1111/jnc.15751

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15751
  219. www.sciencedirect.com www.sciencedirect.com
    Chimeric efferocytic receptors improve apoptotic cell clearance and alleviate inflammation
    1
    1. scibot 10 Jan 2023
      plasmid_52963

      DOI: 10.1016/j.cell.2022.11.029

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    sciencedirect.com/science/article/pii/S0092867422015045
  220. Dec 2022
  221. www.embopress.org www.embopress.org
    IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia
    1
    1. scibot 02 Dec 2022
      Addgene_52963

      DOI: 10.15252/emmm.202115631

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    embopress.org/doi/10.15252/emmm.202115631