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Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PEAK1 maintains tight junctions in intestinal epithelial cells and resists colitis by inhibiting autophagy-mediated ZO-1 degradation

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1. scibot 11 Aug 2025
  
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  Addgene_57818
  
  DOI: 10.1038/s41467-025-62107-z
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12290104/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Chromosomal 3p loss and 8q gain drive vasculogenic mimicry via HIF-2α and VE-cadherin activation in uveal melanoma

1
1. scibot 10 Aug 2025
  
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  57818
  
  DOI: 10.1038/s41418-025-01469-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12325912/
Jul 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225014944-main-html.html

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1. scibot 30 Jul 2025
  
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  Addgene_57818
  
  DOI: 10.1016/j.isci.2025.113233
  
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52.53.155.43/8a7e86b214c98c74df42736ab98e65e6d248c877/1-s2.0-S2589004225014944-main-html.html
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Tumor cell-derived osteopontin promotes tumor fibrosis indirectly via tumor-associated macrophages

1
1. scibot 16 May 2025
  
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  57818
  
  DOI: 10.1186/s12967-025-06444-z
  
  Resource: RRID:Addgene_57818
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11992893/
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Methylstat sensitizes ovarian cancer cells to PARP-inhibition by targeting the histone demethylases JMJD1B/C

1
1. scibot 07 Apr 2025
  
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  57818
  
  DOI: 10.1038/s41417-025-00874-z
  
  Resource: RRID:Addgene_57818
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11946898/
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The late-onset Alzheimer’s disease risk factor RHBDF2 is a modifier of microglial TREM2 proteolysis

1
1. scibot 20 Mar 2025
  
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  RRID:Addgene_57818
  
  DOI: 10.26508/lsa.202403080
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11909414/
Dec 2024
www.sciencedirect.com www.sciencedirect.com

3D chromatin hubs as regulatory units of identity and survival in human acute leukemia

1
1. scibot 24 Dec 2024
  
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  RRID:Addgene_57818
  
  DOI: 10.1016/j.molcel.2024.11.040
  
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sciencedirect.com/science/article/pii/S109727652400995X
Sep 2024
www.biorxiv.org www.biorxiv.org

The late onset Alzheimer’s disease risk factor iRhom2/RHBDF2 is a modifier of microglial TREM2 proteolysis

1
1. scibot 29 Sep 2024
  
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  RRID:Addgene_57818
  
  DOI: 10.1101/2024.09.13.612888
  
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biorxiv.org/content/10.1101/2024.09.13.612888v1
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Localized in vivo gene editing of murine cancer-associated fibroblasts

1
1. scibot 26 Sep 2024
  
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  57818
  
  DOI: 10.1101/2024.07.11.603114
  
  Resource: RRID:Addgene_57818
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11275728/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ADAMTS12 promotes fibrosis by restructuring extracellular matrix to enable activation of injury-responsive fibroblasts

1
1. scibot 25 Sep 2024
  
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  57818
  
  DOI: 10.1172/JCI170246
  
  Resource: RRID:Addgene_57818
  
  Curator: @olekpark
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11405035/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Integrative functional genomic analyses identify genetic variants influencing skin pigmentation in Africans

1
1. scibot 13 Aug 2024
  
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  57818
  
  DOI: 10.1038/s41588-023-01626-1
  
  Resource: RRID:Addgene_57818
  
  Curator: @olekpark
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11005318/
May 2024
www.sciencedirect.com www.sciencedirect.com

Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes

1
1. scibot 17 May 2024
  
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  Addgene_57818
  
  DOI: 10.1016/j.celrep.2021.108887
  
  Resource: RRID:Addgene_57818
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_57818
  
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  RRIDCUR:Validated RRID:Addgene_57818
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sciencedirect.com/science/article/pii/S2211124721002011
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Metabolic signature and response to glutamine deprivation are independent of p53 status in B cell malignancies

1
1. scibot 29 Apr 2024
  
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  57818
  
  DOI: 10.1016/j.isci.2024.109640
  
  Resource: RRID:Addgene_57818
  
  Curator: @olekpark
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11053310/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Efficient deletion of microRNAs using CRISPR/Cas9 with dual guide RNAs

1
1. scibot 23 Apr 2024
  
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  plasmid_57818
  
  DOI: 10.3389/fmolb.2023.1295507
  
  Resource: RRID:Addgene_57818
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11020096/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cullin-RING E3 ubiquitin ligase 4 regulates neurite morphogenesis during neurodevelopment

1
1. scibot 08 Feb 2024
  
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  plasmid_57818
  
  DOI: 10.1016/j.isci.2024.108933
  
  Resource: RRID:Addgene_57818
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10839267/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Nucleolar protein TAAP1/C22orf46 confers pro-survival signaling in non-small cell lung cancer

1
1. scibot 05 Feb 2024
  
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  57818
  
  DOI: 10.26508/lsa.202302257
  
  Resource: RRID:Addgene_57818
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10791977/
Sep 2023
www.sciencedirect.com www.sciencedirect.com

TMEM127 suppresses tumor development by promoting RET ubiquitination, positioning, and degradation

1
1. scibot 07 Sep 2023
  
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  plasmid_57818
  
  DOI: 10.1016/j.celrep.2023.113070
  
  Resource: RRID:Addgene_57818
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124723010811
Dec 2022
aacrjournals.org aacrjournals.org

Efficient Correction of Oncogenic KRAS and TP53 Mutations through CRISPR Base Editing

1
1. scibot 24 Dec 2022
  
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  RRID:Addgene_57818
  
  DOI: 10.1158/0008-5472.CAN-21-2519
  
  Resource: RRID:Addgene_57818
  
  Curator: @scibot
  
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  RRID:Addgene_57818
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aacrjournals.org/cancerres/article/82/17/3002/708290/Efficient-Correction-of-Oncogenic-KRAS-and-TP53
Apr 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SynNotch CAR Circuits Enhance Solid Tumor Recognition and Promote Persistent Anti-tumor Activity in Mouse Models

1
1. scibot 29 Apr 2022
  
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  plasmid_57818
  
  DOI: 10.1126/scitranslmed.abd8836
  
  Resource: RRID:Addgene_57818
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8594452/
Mar 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SOX4 facilitates PGR protein stability and FOXO1 expression conducive for human endometrial decidualization

1
1. scibot 18 Mar 2022
  
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  plasmid_57818
  
  DOI: 10.7554/eLife.72073
  
  Resource: RRID:Addgene_57818
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_57818
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8923662/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

RNAi-Mediated Screen of Primary AML Cells Nominates MDM4 as a Therapeutic Target in NK-AML with DNMT3A Mutations

1
1. scibot 15 Mar 2022
  
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  plasmid_57818
  
  DOI: 10.3390/cells11050854
  
  Resource: RRID:Addgene_57818
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8909053/
Feb 2022
www.sciencedirect.com www.sciencedirect.com

HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia

1
1. scibot 18 Feb 2022
  
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  RRID:Addgene_57818
  
  DOI: 10.1016/j.molcel.2022.01.014
  
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sciencedirect.com/science/article/pii/S1097276522000570
Mar 2021
www.sciencedirect.com www.sciencedirect.com

Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes

1
1. scibot 24 Mar 2021
  
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  Addgene_57818
  
  DOI: 10.1016/j.celrep.2021.108887
  
  Resource: RRID:Addgene_57818
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124721002011
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Follistatin is a novel therapeutic target and biomarker in FLT3/ITD acute myeloid leukemia

1
1. scibot 09 Mar 2021
  
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  Addgene_57818
  
  DOI: 10.15252/emmm.201910895
  
  Resource: RRID:Addgene_57818
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7136967/
www.cell.com www.cell.com

3D Genome of macaque fetal brain reveals evolutionary innovations during primate corticogenesis

1
1. scibot 08 Mar 2021
  
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  Addgene_57818
  
  DOI: 10.1016/j.cell.2021.01.001
  
  Resource: RRID:Addgene_57818
  
  Curator: @scibot
  
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  RRID:Addgene_57818
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cell.com/cell/fulltext/S0092-8674(21)00001-5
Jan 2020
www.sciencedirect.com www.sciencedirect.com

HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice

1
1. scibot 13 Jan 2020
  
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  RRID:Addgene_57818
  
  DOI: 10.1016/j.ccell.2019.10.011
  
  Resource: RRID:Addgene_57818
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_57818
  
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  RRID:Addgene_57818 RRIDCUR:Validated
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RRIDCUR:Validated

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sciencedirect.com/science/article/pii/S1535610819304854
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 12 Jan 2020
  
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  plasmid_57818
  
  DOI: 10.1016/j.celrep.2019.01.006
  
  Resource: RRID:Addgene_57818
  
  Curator: @ethanbadger
  
  SciCrunch record: plasmid_57818
  
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  RRID:Addgene_57818 RRIDCUR:Validated
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RRIDCUR:Validated

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scibot

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sciencedirect.com/science/article/pii/S2211124719300063