35 Matching Annotations
  1. Sep 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Doxycycline-Mediated Control of Cyclin D2 Overexpression in Human-Induced Pluripotent Stem Cells
    1
    1. scibot 29 Sep 2024
      57822

      DOI: 10.3390/ijms25168714

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    ncbi.nlm.nih.gov/pmc/articles/PMC11354523/
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-CLEAR: Nucleotide-Resolution Mapping of Regulatory Elements via Allelic Readout of Tiled Base Editing
    2
    1. scibot 29 Sep 2024
      57822

      DOI: 10.1101/2024.09.09.612085

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    2. scibot 29 Sep 2024
      57822

      DOI: 10.1101/2024.09.09.612085

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    ncbi.nlm.nih.gov/pmc/articles/PMC11419122/
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BOD1L mediates chromatin binding and non-canonical function of H3K4 methyltransferase SETD1A
    1
    1. scibot 28 Sep 2024
      Addgene_57822

      DOI: 10.1093/nar/gkae605

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    ncbi.nlm.nih.gov/pmc/articles/PMC11381347/
  5. Aug 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrative functional genomic analyses identify genetic variants influencing skin pigmentation in Africans
    1
    1. scibot 13 Aug 2024
      57822

      DOI: 10.1038/s41588-023-01626-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11005318/
  7. Jul 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer
    2
    1. scibot 31 Jul 2024
      RRID:Addgene_57822

      DOI: 10.1158/2159-8290.CD-23-0539

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    2. scibot 31 Jul 2024
      RRID:Addgene_57822

      DOI: 10.1158/2159-8290.CD-23-0539

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    ncbi.nlm.nih.gov/pmc/articles/PMC11285331/
  9. Jun 2024
  10. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
    1
    1. scibot 28 Jun 2024
      RRID:Addgene_57822

      DOI: 10.1002/1878-0261.13672

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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13672
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA splicing analysis deciphers developmental hierarchies and reveals therapeutic targets in adult glioma
    1
    1. scibot 03 Jun 2024
      57822

      DOI: 10.1172/JCI173789

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    ncbi.nlm.nih.gov/pmc/articles/PMC11142752/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Precise correction of a spectrum of β-thalassemia mutations in coding and non-coding regions by base editors
    2
    1. scibot 03 Jun 2024
      Addgene_57822

      DOI: 10.1016/j.omtn.2024.102205

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    2. scibot 03 Jun 2024
      Addgene_57822

      DOI: 10.1016/j.omtn.2024.102205

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    ncbi.nlm.nih.gov/pmc/articles/PMC11137594/
  13. Apr 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor Cell-Associated IL-1α Affects Breast Cancer Progression and Metastasis in Mice through Manipulation of the Tumor Immune Microenvironment
    1
    1. scibot 18 Apr 2024
      RRID:Addgene_57822

      DOI: 10.3390/ijms25073950

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    ncbi.nlm.nih.gov/pmc/articles/PMC11011794/
  15. Feb 2024
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapeutic targeting Tudor domains in leukemia via CRISPR-Scan Assisted Drug Discovery
    1
    1. scibot 29 Feb 2024
      57822

      DOI: 10.1126/sciadv.adk3127

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    ncbi.nlm.nih.gov/pmc/articles/PMC10889360/
  17. Dec 2023
  18. www.sciencedirect.com www.sciencedirect.com
    SON is an essential m6A target for hematopoietic stem cell fate
    1
    1. scibot 17 Dec 2023
      Addgene_57822

      DOI: 10.1016/j.stem.2023.11.006

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    sciencedirect.com/science/article/pii/S1934590923003983
  19. Nov 2023
  20. www.biorxiv.org www.biorxiv.org
    ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers
    1
    1. scibot 03 Nov 2023
      RRID:Addgene_57822

      DOI: 10.1101/2023.10.24.563645

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    biorxiv.org/content/10.1101/2023.10.24.563645v1
  21. Aug 2023
  22. 52.53.155.43 52.53.155.43
    Aberrant accumulation of Kras-dependent pervasive transcripts during tumor progression renders cancer cells dependent on PAF1 expression
    2
    1. scibot 16 Aug 2023
      RRID:Addgene_57822

      DOI: 10.1016/j.celrep.2023.112979

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    2. scibot 16 Aug 2023
      RRID:Addgene_57822

      DOI: 10.1016/j.celrep.2023.112979

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    52.53.155.43/491f3628ae56ca418965e7c0fc6856d1761b345d/PIIS2211124723009907-html.html
  23. May 2023
  24. www.biorxiv.org www.biorxiv.org
    Group comparison based on genetic information reveals lineage-specific therapeutic vulnerabilities in acute myeloid leukemia
    1
    1. scibot 25 May 2023
      RRID:Addgene_57822

      DOI: 10.1101/2023.05.18.541265

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    biorxiv.org/content/10.1101/2023.05.18.541265v1
  25. Mar 2023
  26. www.sciencedirect.com www.sciencedirect.com
    In vivo interrogation of regulatory genomes reveals extensive quasi-insufficiency in cancer evolution
    1
    1. scibot 11 Mar 2023
      RRID:Addgene_57822

      DOI: 10.1016/j.xgen.2023.100276

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    sciencedirect.com/science/article/pii/S2666979X23000368
  27. Jan 2023
  28. www.sciencedirect.com www.sciencedirect.com
    Genetic screens reveal new targetable vulnerabilities in BAP1-deficient mesothelioma
    1
    1. scibot 19 Jan 2023
      Addgene_57822

      DOI: 10.1016/j.xcrm.2022.100915

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    sciencedirect.com/science/article/pii/S2666379122004943
  29. www.sciencedirect.com www.sciencedirect.com
    Controlling organoid symmetry breaking uncovers an excitable system underlying human axial elongation
    1
    1. scibot 19 Jan 2023
      RRID:Addgene_57822

      DOI: 10.1016/j.cell.2022.12.043

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    sciencedirect.com/science/article/pii/S0092867422015860
  30. Dec 2022
  31. www.sciencedirect.com www.sciencedirect.com
    SETD1A regulates transcriptional pause release of heme biosynthesis genes in leukemia
    1
    1. scibot 01 Dec 2022
      Addgene_57822

      DOI: 10.1016/j.celrep.2022.111727

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    sciencedirect.com/science/article/pii/S2211124722016059
  32. Mar 2022
  33. www.sciencedirect.com www.sciencedirect.com
    The PAF1 complex promotes 3′ processing of pervasive transcripts
    1
    1. scibot 16 Mar 2022
      Addgene_57822

      DOI: 10.1016/j.celrep.2022.110519

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    sciencedirect.com/science/article/pii/S2211124722002558
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin
    1
    1. scibot 04 Mar 2022
      RRID:Addgene_57822

      DOI: 10.7554/eLife.65421

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    ncbi.nlm.nih.gov/pmc/articles/PMC8865852/
  35. Jan 2022
  36. www.sciencedirect.com www.sciencedirect.com
    Modeling cell protrusion predicts how Myosin II and actin turnover affect adhesion-based signaling
    1
    1. scibot 12 Jan 2022
      RRID:Addgene_57822

      DOI: 10.1016/j.bpj.2021.11.2889

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    sciencedirect.com/science/article/pii/S0006349521038820
  37. Dec 2021
  38. link.springer.com link.springer.com
    Loss of hexokinase 1 sensitizes ovarian cancer to high-dose metformin
    1
    1. scibot 15 Dec 2021
      RRID:Addgene_57822

      DOI: 10.1186/s40170-021-00277-2

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    link.springer.com/article/10.1186/s40170-021-00277-2
  39. Sep 2021
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis
    1
    1. scibot 04 Sep 2021
      RRID:Addgene_57822

      DOI: 10.7554/eLife.65872

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    ncbi.nlm.nih.gov/pmc/articles/PMC8387021/
  41. Aug 2021
  42. elifesciences.org elifesciences.org
    HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways
    1
    1. scibot 15 Aug 2021
      RRID:Addgene_57822

      DOI: 10.7554/eLife.64148

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    elifesciences.org/articles/64148
  43. www.sciencedirect.com www.sciencedirect.com
    Aberrant Activation of a Gastrointestinal Transcriptional Circuit in Prostate Cancer Mediates Castration Resistance
    1
    1. scibot 11 Aug 2021
      plasmid_57822

      DOI: 10.1016/j.ccell.2017.10.008

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    sciencedirect.com/science/article/pii/S1535610817304610
  44. Jul 2021
  45. www.cell.com www.cell.com
    Untitled document
    1
    1. scibot 28 Jul 2021
      plasmid_57822

      DOI: 10.1016/j.ccell.2017.10.008

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    cell.com/cancer-cell/abstract/S1535-6108(17)30461-0
  46. Feb 2021
  47. www.sciencedirect.com www.sciencedirect.com
    Vitamin B6 Addiction in Acute Myeloid Leukemia
    1
    1. scibot 24 Feb 2021
      plasmid_57822

      DOI: 10.1016/j.ccell.2019.12.002

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    sciencedirect.com/science/article/pii/S1535610819305720
  48. Sep 2020
  49. www.sciencedirect.com www.sciencedirect.com
    Activation of CpG-Rich Promoters Mediated by MLL Drives MOZ-Rearranged Leukemia
    1
    1. scibot 30 Sep 2020
      Plasmid_57822

      DOI: 10.1016/j.celrep.2020.108200

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      Curator: @Naa003

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      RRID:Addgene_57822 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S221112472031189X
  50. www.sciencedirect.com www.sciencedirect.com
    CXCR4 Signaling Has a CXCL12-Independent Essential Role in Murine MLL-AF9-Driven Acute Myeloid Leukemia
    1
    1. scibot 06 Sep 2020
      RRID:Addgene_57822

      DOI: 10.1016/j.celrep.2020.107684

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S2211124720306379
  51. Aug 2020
  52. www.sciencedirect.com www.sciencedirect.com
    Vitamin B6 Addiction in Acute Myeloid Leukemia
    1
    1. scibot 14 Aug 2020
      Addgene plasmid # 57822

      DOI: 10.1016/j.ccell.2019.12.002

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S1535610819305720
  53. Jan 2020
  54. www.sciencedirect.com www.sciencedirect.com
    Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_57822

      DOI: 10.1016/j.immuni.2019.08.006

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    sciencedirect.com/science/article/pii/S1074761319303322