36 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A multiplexed gRNA piggyBac transposon system facilitates efficient induction of CRISPRi and CRISPRa in human pluripotent stem cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC6971260/
  3. Jul 2026
  4. www.sciencedirect.com www.sciencedirect.com
    Protocol for the generation of human medullary spinal trigeminal nucleus-like organoids and trigeminothalamic assembloids
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    sciencedirect.com/science/article/pii/S2666166726003588
  5. Jun 2026
  6. 54.241.53.176 54.241.53.176
    2026.06.04.730242.full-html.html
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    54.241.53.176/880a3fee5b49e4dd23b88b08dfca54c5c7493374/2026.06.04.730242.full-html.html
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Healthy donor T cell receptors expand functional neoantigen recognition beyond patient vaccination
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    pmc.ncbi.nlm.nih.gov/articles/PMC13089343/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Whole-genome CRISPR screening identifies genetic modifiers of stem cell–derived islet transplantation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13168893/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of immunogenic neoantigens from intron retention in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13096189/
  10. May 2026
  11. www.sciencedirect.com www.sciencedirect.com
    Human pancreatic progenitor organoids define genetic and epigenetic barriers to early PDAC transformation
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    sciencedirect.com/science/article/pii/S1534580726001590
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Human stem cell-derived β cells expressing an optimized CD155 reduce cytotoxic immune cell function for application in type 1 diabetes
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    pmc.ncbi.nlm.nih.gov/articles/PMC13142048/
  13. Mar 2026
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome-wide CRISPR screen identifies neddylation as a regulator of neuronal aging and AD neurodegeneration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12973372/
  15. Nov 2025
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combining genome and tissue engineering for next-generation human biomimetics
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    pmc.ncbi.nlm.nih.gov/articles/PMC12629539/
  17. Aug 2025
  18. www.biorxiv.org www.biorxiv.org
    Human Stem Cell-Derived β-cells Expressing An Optimized CD155 Reduce Cytotoxic Immune Cell Function for Application in Type 1 Diabetes
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    biorxiv.org/content/10.1101/2025.08.12.669867v1
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Extended NGN2 Expression in iPSCs Dramatically Enhances Purity of Neuronal Cultures
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    pmc.ncbi.nlm.nih.gov/articles/PMC12262333/
  20. Jun 2025
  21. www.sciencedirect.com www.sciencedirect.com
    A novel “chassis” PSC line for precise safe harbor site integration via selection-aided RMCE
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    sciencedirect.com/science/article/pii/S1873506125001084
  22. May 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High-Throughput Screening to Identify Novel Compounds Affecting the Genome Editing Efficiency of CRISPR System
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    pmc.ncbi.nlm.nih.gov/articles/PMC12029788/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Elevated p16Ink4a Expression Enhances Tau Phosphorylation in Neurons Differentiated From Human‐Induced Pluripotent Stem Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12073902/
  25. Feb 2025
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Recombinase-Mediated Cassette Exchange Platform for a Triple Independent Inducible Expression System for Human Pluripotent Stem Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11817695/
  27. Jan 2025
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NHSL3 controls single and collective cell migration through two distinct mechanisms
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    pmc.ncbi.nlm.nih.gov/articles/PMC11696792/
  29. Dec 2024
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identifying key underlying regulatory networks and predicting targets of orphan C/D box SNORD116 snoRNAs in Prader–Willi syndrome
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    pmc.ncbi.nlm.nih.gov/articles/PMC11662933/
  31. www.sciencedirect.com www.sciencedirect.com
    Combinatorial genetic engineering strategy for immune protection of stem cell-derived beta cells by chimeric antigen receptor regulatory T cells
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    sciencedirect.com/science/article/pii/S2211124724013457
  32. www.sciencedirect.com www.sciencedirect.com
    Generation of self-organized neuromusculoskeletal tri-tissue organoids from human pluripotent stem cells
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    sciencedirect.com/science/article/pii/S1934590924004041
  33. Jun 2024
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Farnesyltransferase inhibition overcomes oncogene-addicted non-small cell lung cancer adaptive resistance to targeted therapies
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    ncbi.nlm.nih.gov/pmc/articles/PMC11211478/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A dynamic in vitro model of Down syndrome neurogenesis with trisomy 21 gene dosage correction
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    ncbi.nlm.nih.gov/pmc/articles/PMC11160455/
  36. Apr 2024
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Circular RNA as a source of neoantigens for cancer vaccines
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    ncbi.nlm.nih.gov/pmc/articles/PMC10952939/
  38. Feb 2024
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Liver regulatory mechanisms of noncoding variants at lipid and metabolic trait loci
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    ncbi.nlm.nih.gov/pmc/articles/PMC10881423/
  40. Dec 2023
  41. www.sciencedirect.com www.sciencedirect.com
    Early Alzheimer’s disease pathology in human cortex involves transient cell states
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    sciencedirect.com/science/article/pii/S0092867423008590
  42. Oct 2023
  43. 52.53.155.43 52.53.155.43
    BRD9-SMAD2/3 orchestrates stemness and tumorigenesis in pancreatic ductal adenocarcinoma
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    52.53.155.43/7e131b55ec1d758dbf0613142d9050421d02fd72/1-s2.0-S0016508523050126-main-html.html
  44. Dec 2022
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human stem cell derived beta-like cells engineered to present PD-L1 improve transplant survival in NOD mice carrying human HLA class I
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    ncbi.nlm.nih.gov/pmc/articles/PMC9732725/
  46. Aug 2022
  47. www.science.org www.science.org
    CRISPR interference interrogation of COPD GWAS genes reveals the functional significance of desmoplakin in iPSC-derived alveolar epithelial cells
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    science.org/doi/10.1126/sciadv.abo6566
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR interference interrogation of COPD GWAS genes reveals the functional significance of desmoplakin in iPSC-derived alveolar epithelial cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9278866/
  49. Mar 2022
  50. www.sciencedirect.com www.sciencedirect.com
    dCas9 fusion to computer-designed PRC2 inhibitor reveals functional TATA box in distal promoter region
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    sciencedirect.com/science/article/pii/S221112472200184X
  51. Dec 2021
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Establishment of a human induced pluripotent stem cell neuronal model for identification of modulators of A53T α-synuclein levels and aggregation
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    ncbi.nlm.nih.gov/pmc/articles/PMC8691628/
  53. Aug 2021
  54. www.sciencedirect.com www.sciencedirect.com
    Selective deletion of human leukocyte antigens protects stem cell-derived islets from immune rejection
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    sciencedirect.com/science/article/pii/S2211124721009724
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protecting Stem Cell Derived Pancreatic Beta-Like Cells From Diabetogenic T Cell Recognition
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    ncbi.nlm.nih.gov/pmc/articles/PMC8299417/
  56. Feb 2021
  57. www.sciencedirect.com www.sciencedirect.com
    Generation of two gene edited iPSC-lines carrying a DOX-inducible NGN2 expression cassette with and without GFP in the AAVS1 locus
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    sciencedirect.com/science/article/pii/S1873506121000866
  58. Sep 2020
  59. www.sciencedirect.com www.sciencedirect.com
    Dysregulation of BRD4 Function Underlies the Functional Abnormalities of MeCP2 Mutant Neurons
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    sciencedirect.com/science/article/pii/S1097276520303178
  60. Jan 2020
  61. www.sciencedirect.com www.sciencedirect.com
    hESC-Derived Thalamic Organoids Form Reciprocal Projections When Fused with Cortical Organoids
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    sciencedirect.com/science/article/pii/S1934590918306052