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Chromatin condensates tune nuclear mechanosensing and preserve nuclear integrity to prevent cGAS activation

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1. scibot 20 Aug 2026
  
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  Addgene_60954
  
  DOI: 10.1038/s44318-026-00884-z
  
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link.springer.com/article/10.1038/s44318-026-00884-z
Aug 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

EMT activates ER-to-Golgi trafficking through upregulation of REEP2 to promote lung cancer progression

1
1. scibot 08 Aug 2026
  
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  60954
  
  DOI: 10.21203/rs.3.rs-8117355/v1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13419587/
Jun 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Transposable elements shape stemness in normal and leukemic hematopoiesis

2
1. scibot 06 Jun 2026
  
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  60954
  
  DOI: 10.1038/s41588-026-02585-z
  
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2. scibot 06 Jun 2026
  
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  60954
  
  DOI: 10.1038/s41588-026-02585-z
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13175892/
Apr 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

De novo design of Ras isoform selective binders

1
1. scibot 08 Apr 2026
  
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  60954
  
  DOI: 10.1016/j.chembiol.2026.02.008
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12982892/
Jan 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

EMT activates ER-to-Golgi trafficking through upregulation of REEP2 to promote lung cancer progression

1
1. scibot 26 Jan 2026
  
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  60954
  
  DOI: 10.1101/2025.11.12.688098
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12642484/
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Cyclin D1 overexpression induces replication stress and microhomology-mediated end-joining dependence in mantle cell lymphoma

1
1. scibot 06 Sep 2025
  
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  60954
  
  DOI: 10.1172/JCI193006
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12404763/
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Disruption of TAD hierarchy promotes LTR co-option in cancer

1
1. scibot 11 Aug 2025
  
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  60954
  
  DOI: 10.1038/s41588-025-02239-6
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12283374/
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Large-scale experimental assessment of variant effects on the structure and function of the citrate transporter SLC13A5

1
1. scibot 20 Jul 2025
  
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  60954
  
  DOI: 10.1126/sciadv.adx3011
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12204159/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Novel drug-inducible CRISPRa/i systems for rapid and reversible manipulation of gene transcription

1
1. scibot 20 Jul 2025
  
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  plasmid_60954
  
  DOI: 10.1007/s00018-025-05786-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12185803/
May 2025
onlinelibrary.wiley.com onlinelibrary.wiley.com

Identification of a Distal Enhancer That Regulates TGF-β–Induced SNAI1 Expression

2
1. scibot 20 May 2025
  
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  plasmid_60954
  
  DOI: 10.1111/cas.70091
  
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2. scibot 16 May 2025
  
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  RRID: Addgene_60,954
  
  DOI: 10.1111/cas.70091
  
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  Curator: @dhovakimyan1
  
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onlinelibrary.wiley.com/doi/10.1111/cas.70091
Apr 2025
www.sciencedirect.com www.sciencedirect.com

An ultraconserved snoRNA-like element in long noncoding RNA CRNDE promotes ribosome biogenesis and cell proliferation

1
1. scibot 05 Apr 2025
  
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  RRID:Addgene_60954
  
  DOI: 10.1016/j.molcel.2025.03.006
  
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sciencedirect.com/science/article/pii/S1097276525001996
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

De novo design of Ras isoform selective binders

1
1. scibot 11 Mar 2025
  
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  60954
  
  DOI: 10.1101/2024.08.29.610300
  
  Resource: RRID:Addgene_60954
  
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  DOI:10.1101/2024.08.29.610300 RRID:Addgene_60954
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DOI:10.1101/2024.08.29.610300

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pmc.ncbi.nlm.nih.gov/articles/PMC11838417/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Inhibition of the STAT3/Fanconi anemia axis is synthetic lethal with PARP inhibition in breast cancer

1
1. scibot 11 Mar 2025
  
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  Plasmid_60954
  
  DOI: 10.1038/s41467-025-57476-4
  
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  RRID:Addgene_60954
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pmc.ncbi.nlm.nih.gov/articles/PMC11880418/
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A single-cell CRISPRi platform for characterizing candidate genes relevant to metabolic disorders in human adipocytes

1
1. scibot 06 Sep 2024
  
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  Addgene, No. 60954
  
  DOI: 10.1152/ajpcell.00148.2023
  
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  Curator: @vtello
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10635647/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

An ultraconserved snoRNA-like element in long noncoding RNA CRNDE promotes ribosome biogenesis and cell proliferation

1
1. scibot 22 Aug 2024
  
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  Addgene_60954
  
  DOI: 10.1101/2024.07.23.604857
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11291168/
Jul 2024
www.sciencedirect.com www.sciencedirect.com

Interface-guided phenotyping of coding variants in the transcription factor RUNX1

1
1. scibot 18 Jul 2024
  
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  Addgene_60954
  
  DOI: 10.1016/j.celrep.2024.114436
  
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sciencedirect.com/science/article/pii/S2211124724007654
www.cell.com www.cell.com

A non-canonical role for a small nucleolar RNA in ribosome biogenesis and senescence

1
1. scibot 11 Jul 2024
  
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  RRID:Addgene_60954
  
  DOI: 10.1016/j.cell.2024.06.019
  
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cell.com/cell/fulltext/S0092-8674(24)00693-7
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

In Vivo Genome-Wide CRISPR Screening Identifies CITED2 as a Driver of Prostate Cancer Bone Metastasis

1
1. scibot 21 Jun 2024
  
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  Addgene_60954
  
  DOI: 10.1038/s41388-024-02995-5
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11101692/
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The construction of modular universal chimeric antigen receptor T (MU-CAR-T) cells by covalent linkage of allogeneic T cells and various antibody fragments

1
1. scibot 16 Mar 2024
  
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  Addgene_60
  
  DOI: 10.1186/s12943-024-01938-8
  
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  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_60954
  
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  RRIDCUR:Incorrect RRID:Addgene_60954 RRIDCUR:Unresolved
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ncbi.nlm.nih.gov/pmc/articles/PMC10926606/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A functional genomic framework to elucidate novel causal non-alcoholic fatty liver disease genes

1
1. scibot 02 Mar 2024
  
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  60954
  
  DOI: 10.1101/2024.02.03.24302258
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10863038/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The chromatin-associated lncREST ensures effective replication stress response by promoting the assembly of fork signaling factors

1
1. scibot 04 Feb 2024
  
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  60954
  
  DOI: 10.1038/s41467-024-45183-5
  
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  RRID:Addgene_60954
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ncbi.nlm.nih.gov/pmc/articles/PMC10834948/
Sep 2023
www.sciencedirect.com www.sciencedirect.com

TOBF1 modulates mouse embryonic stem cell fate through regulating alternative splicing of pluripotency genes

1
1. scibot 30 Sep 2023
  
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  RRID:Addgene_60954
  
  DOI: 10.1016/j.celrep.2023.113177
  
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sciencedirect.com/science/article/pii/S2211124723011890
www.sciencedirect.com www.sciencedirect.com

Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment

1
1. scibot 16 Sep 2023
  
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  RRID:Addgene_60954
  
  DOI: 10.1016/j.celrep.2023.113098
  
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  RRID:Addgene_60954
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sciencedirect.com/science/article/pii/S2211124723011099
Jun 2023
genome.cshlp.org genome.cshlp.org

Multiplexed long-read plasmid validation and analysis using OnRamp

1
1. scibot 16 Jun 2023
  
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  RRID:Addgene_60954
  
  DOI: 10.1101/gr.277369.122
  
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  RRID:Addgene_60954
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genome.cshlp.org/content/33/5/741
Jan 2023
www.sciencedirect.com www.sciencedirect.com

Production of CRISPRi-engineered primary human mammary epithelial cells with baboon envelope pseudotyped lentiviral vectors

1
1. scibot 21 Jan 2023
  
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  RRID:Addgene_60954
  
  DOI: 10.1016/j.xpro.2023.102055
  
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sciencedirect.com/science/article/pii/S2666166723000138
May 2022
www.sciencedirect.com www.sciencedirect.com

XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation

1
1. scibot 25 May 2022
  
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  Plasmid_60954
  
  DOI: 10.1016/j.cell.2022.04.034
  
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sciencedirect.com/science/article/pii/S0092867422005323
Feb 2022
www.sciencedirect.com www.sciencedirect.com

Identification of an endoplasmic reticulum proteostasis modulator that enhances insulin production in pancreatic β cells

2
1. scibot 11 Feb 2022
  
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  Addgene 60954
  
  DOI: 10.1016/j.chembiol.2022.01.002
  
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  Curator: @sophiastull
  
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  RRID:Addgene_60954
2. scibot 11 Feb 2022
  
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  Addgene 60954
  
  DOI: 10.1016/j.chembiol.2022.01.002
  
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  Curator: @sophiastull
  
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  RRID:Addgene_60954
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sciencedirect.com/science/article/pii/S2451945622000022
Sep 2021
iovs.arvojournals.org iovs.arvojournals.org

Using CRISPR Interference as a Therapeutic Approach to Treat TGFβ2-Induced Ocular Hypertension and Glaucoma

1
1. scibot 16 Sep 2021
  
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  RRID:Addgene_60954
  
  DOI: 10.1167/iovs.62.12.7
  
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  RRID:Addgene_60954
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iovs.arvojournals.org/article.aspx
Aug 2021
elifesciences.org elifesciences.org

Untitled document

1
1. scibot 07 Aug 2021
  
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  plasmid_60954
  
  DOI: 10.7554/eLife.31023
  
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elifesciences.org/articles/31023
May 2021
www.sciencedirect.com www.sciencedirect.com

Tumor Interferon Signaling Is Regulated by a lncRNA INCR1 Transcribed from the PD-L1 Locus

1
1. scibot 07 May 2021
  
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  Plasmid_60954
  
  DOI: 10.1016/j.molcel.2020.05.015
  
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sciencedirect.com/science/article/pii/S1097276520303166
Feb 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cohesin-Dependent and -Independent Mechanisms Mediate Chromosomal Contacts between Promoters and Enhancers

1
1. scibot 26 Feb 2021
  
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  plasmid_60954
  
  DOI: 10.1016/j.celrep.2020.107929
  
  Resource: RRID:Addgene_60954
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7383238/
Jan 2021
www.sciencedirect.com www.sciencedirect.com

Proteome dynamics at broken replication forks reveal a distinct ATM-directed repair response suppressing DNA double-strand break ubiquitination

1
1. scibot 21 Jan 2021
  
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  pHR-SFFV-KRAB-dCas9-2A- CHERRY
  
  DOI: 10.1016/j.molcel.2020.12.025
  
  Resource: RRID:Addgene_60954
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_60954
  
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  RRIDCUR:Missing RRID:Addgene_60954
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sciencedirect.com/science/article/pii/S1097276520309461
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Identification and Massively Parallel Characterization of Regulatory Elements Driving Neural Induction

1
1. scibot 13 Jan 2020
  
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  RRID:Addgene_60954
  
  DOI: 10.1016/j.stem.2019.09.010
  
  Resource: RRID:Addgene_60954
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_60954
  
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  RRID:Addgene_60954 RRIDCUR:Validated
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RRIDCUR:Validated

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sciencedirect.com/science/article/pii/S1934590919304217