34 Matching Annotations
  1. Aug 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Suppression of HSV-1 infection and viral reactivation by CRISPR-Cas9 gene editing in 2D and 3D culture models
    1
    1. scibot 26 Aug 2024
      61591

      DOI: 10.1016/j.omtn.2024.102282

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    ncbi.nlm.nih.gov/pmc/articles/PMC11339036/
  3. www.cell.com www.cell.com
    Upregulation of utrophin improves the phenotype of Duchenne muscular dystrophy hiPSC-derived CMs
    1
    1. scibot 26 Aug 2024
      Addgene_6159163

      DOI: 10.1016/j.omtn.2024.102247

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    cell.com/molecular-therapy-family/nucleic-acids/abstract/S2162-2531(24)00134-3
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome editing in the mouse brain with minimally immunogenic Cas9 RNPs
    1
    1. scibot 18 Aug 2024
      RRID:Addgene_61591

      DOI: 10.1016/j.ymthe.2023.06.019

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    ncbi.nlm.nih.gov/pmc/articles/PMC10422012/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeted genome editing restores auditory function in adult mice with progressive hearing loss caused by a human microRNA mutation
    1
    1. scibot 13 Aug 2024
      61591

      DOI: 10.1126/scitranslmed.adn0689

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    ncbi.nlm.nih.gov/pmc/articles/PMC7616320/
  6. Jul 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long term rescue of Alzheimer’s deficits in vivo by one-time gene-editing of App C-terminus
    1
    1. scibot 01 Jul 2024
      Addgene_61591

      DOI: 10.1101/2024.06.08.598099

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    ncbi.nlm.nih.gov/pmc/articles/PMC11185791/
  8. Jun 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Conditional knockout of Shank3 in the ventral CA1 by quantitative in vivo genome-editing impairs social memory in mice
    1
    1. scibot 15 Jun 2024
      plasmid_61591

      DOI: 10.1038/s41467-024-48430-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC11169449/
  10. 52.53.155.43 52.53.155.43
    Optimization of AAV vectors for transactivator-regulated enhanced gene expression within targeted neuronal populations.
    1
    1. scibot 06 Jun 2024
      RRID:Addgene_6159

      DOI: 10.1016/j.isci.2024.109878

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    52.53.155.43/7f9ee4f71b8a925e453a4463d9dde20f671e0e7e/PIIS2589004224011003-html.html
  11. May 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vivo genome editing via CRISPR/Cas9-mediated homology-independent targeted integration for Bietti crystalline corneoretinal dystrophy treatment
    1
    1. scibot 12 May 2024
      61591

      DOI: 10.1038/s41467-024-48092-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC11074121/
  13. Mar 2024
  14. 52.53.155.43 52.53.155.43
    Efficient and safe therapeutic use of paired Cas9-nickases for primary hyperoxaluria type 1
    2
    1. scibot 21 Mar 2024
      RRID:Addgene_61591

      DOI: 10.1038/s44321-023-00008-8

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    2. scibot 02 Mar 2024
      RRID:Addgene_61591

      DOI: 10.1038/s44321-023-00008-8

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    52.53.155.43/b4a5d5f166b97df7aae394dba3752d5bbdf7ed06/torella-et-al-2024-efficient-and-safe-therapeutic-use-of-paired-cas9-nickases-for-primary-hyperoxaluria-type-1-html.html
  15. Nov 2023
  16. www.sciencedirect.com www.sciencedirect.com
    Unexpected extra exon skipping in the DYSF gene during restoring the reading frame by CRISPR/Cas9
    1
    1. scibot 17 Nov 2023
      RRID:Addgene_61591

      DOI: 10.1016/j.biosystems.2023.105072

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    sciencedirect.com/science/article/pii/S0303264723002472
  17. Sep 2023
  18. www.mdpi.com www.mdpi.com
    Targeted Delivery of Chimeric Antigen Receptor into T Cells via CRISPR-Mediated Homology-Directed Repair with a Dual-AAV6 Transduction System
    1
    1. scibot 30 Sep 2023
      RRID:Addgene_61591

      DOI: 10.3390/cimb45100486

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    mdpi.com/1467-3045/45/10/486
  19. Aug 2023
  20. www.sciencedirect.com www.sciencedirect.com
    Neural mechanisms underlying uninstructed orofacial movements during reward-based learning behaviors
    1
    1. scibot 03 Aug 2023
      Addgene_61591

      DOI: 10.1016/j.cub.2023.07.013

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    sciencedirect.com/science/article/pii/S096098222300920X
  21. Jul 2023
  22. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Production of adeno-associated viral vector serotype 6 by triple transfection of suspension HEK293 cells at higher cell densities
    1
    1. scibot 05 Jul 2023
      RRID:Addgene_61591

      DOI: 10.1002/biot.202300051

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    onlinelibrary.wiley.com/doi/10.1002/biot.202300051
  23. May 2023
  24. www.authorea.com www.authorea.com
    High-cell-density production of adeno-associated viral vector serotype 6 by triple transfection in suspension HEK293 cell cultures
    1
    1. scibot 13 May 2023
      RRID:Addgene_61591

      DOI: 10.22541/au.167535214.41739207/v1

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    authorea.com/users/582383/articles/622468-high-cell-density-production-of-adeno-associated-viral-vector-serotype-6-by-triple-transfection-in-suspension-hek293-cell-cultures
  25. Apr 2023
  26. www.biorxiv.org www.biorxiv.org
    Genome editing in the mouse brain with minimally immunogenic Cas9 RNPs
    1
    1. scibot 19 Apr 2023
      RRID:Addgene_61591

      DOI: 10.1101/2023.04.13.536294

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    biorxiv.org/content/10.1101/2023.04.13.536294v1
  27. Mar 2023
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Correction of F8 intron 1 inversion in hemophilia A patient-specific iPSCs by CRISPR/Cas9 mediated gene editing
    1
    1. scibot 26 Mar 2023
      RRID:Addgene_61591

      DOI: 10.3389/fgene.2023.1115831

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    ncbi.nlm.nih.gov/pmc/articles/PMC10033665/
  29. Dec 2022
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-uniform dystrophin re-expression after CRISPR-mediated exon excision in the dystrophin/utrophin double-knockout mouse model of DMD
    1
    1. scibot 02 Dec 2022
      RRID:Addgene_61591

      DOI: 10.1016/j.omtn.2022.10.010

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    ncbi.nlm.nih.gov/pmc/articles/PMC9664411/
  31. Sep 2022
  32. www.sciencedirect.com www.sciencedirect.com
    Generation of a homozygous P4HA2 knockout human embryonic stem cell line (FDCHDPe012-A) by CRISPR/Cas9 system
    1
    1. scibot 30 Sep 2022
      Addgene_61591

      DOI: 10.1016/j.scr.2022.102930

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    sciencedirect.com/science/article/pii/S1873506122002793
  33. Jun 2022
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deficiency in endocannabinoid synthase DAGLB contributes to early onset Parkinsonism and murine nigral dopaminergic neuron dysfunction
    1
    1. scibot 22 Jun 2022
      plasmid_61591

      DOI: 10.1038/s41467-022-31168-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC9205912/
  35. Mar 2022
  36. www.sciencedirect.com www.sciencedirect.com
    Regulation of GTPase function by autophosphorylation
    1
    1. scibot 04 Mar 2022
      AddgeneCat#: 61591

      DOI: 10.1016/j.molcel.2022.02.011

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      Curator: @sophiastull

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    sciencedirect.com/science/article/pii/S1097276522001162
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antiviral Targeting of Varicella Zoster Virus Replication and Neuronal Reactivation Using CRISPR/Cas9 Cleavage of the Duplicated Open Reading Frames 62/71
    1
    1. scibot 04 Mar 2022
      RRID:Addgene_61591

      DOI: 10.3390/v14020378

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    ncbi.nlm.nih.gov/pmc/articles/PMC8880005/
  38. Dec 2021
  39. elifesciences.org elifesciences.org
    scAAVengr, a transcriptome-based pipeline for quantitative ranking of engineered AAVs with single-cell resolution
    2
    1. scibot 01 Dec 2021
      RRID:Addgene_61591

      DOI: 10.7554/eLife.64175

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    2. scibot 01 Dec 2021
      Plasmid_61591RRID

      DOI: 10.7554/eLife.64175

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      Curator: @evieth

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      RRID:Addgene_61591 RRIDCUR:Unresolved
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    elifesciences.org/articles/64175
  40. Oct 2021
  41. www.sciencedirect.com www.sciencedirect.com
    Bombesin-like peptide recruits disinhibitory cortical circuits and enhances fear memories
    1
    1. scibot 05 Oct 2021
      plasmid_61591

      DOI: 10.1016/j.cell.2021.09.013

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    sciencedirect.com/science/article/pii/S0092867421010606
  42. Sep 2021
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unlocking loxP to Track Genome Editing In Vivo
    1
    1. scibot 04 Sep 2021
      RRID:Addgene_61591

      DOI: 10.3390/genes12081204

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    ncbi.nlm.nih.gov/pmc/articles/PMC8394901/
  44. Aug 2021
  45. www.sciencedirect.com www.sciencedirect.com
    Generation of a homozygous LRPAP1 knockout human embryonic stem cell line (FDCHDPe009-B) by CRISPR/Cas9 system
    1
    1. scibot 28 Aug 2021
      Addgene_61591

      DOI: 10.1016/j.scr.2021.102516

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    sciencedirect.com/science/article/pii/S1873506121003639
  46. www.mdpi.com www.mdpi.com
    Adeno-Associated Vector-Delivered CRISPR/SaCas9 System Reduces Feline Leukemia Virus Production In Vitro
    1
    1. scibot 24 Aug 2021
      RRID:Addgene_61591

      DOI: 10.3390/v13081636

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    mdpi.com/1999-4915/13/8/1636/htm
  47. www.jneurosci.org www.jneurosci.org
    Subretinal Human Umbilical Tissue-Derived Cell Transplantation Preserves Retinal Synaptic Connectivity and Attenuates Müller Glial Reactivity
    1
    1. scibot 01 Aug 2021
      Plasmid_61591

      DOI: 10.1523/JNEUROSCI.1532-17.2018

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    jneurosci.org/content/38/12/2923
  48. www.sciencedirect.com www.sciencedirect.com
    CRISPR-READI: Efficient Generation of Knockin Mice by CRISPR RNP Electroporation and AAV Donor Infection
    1
    1. scibot 01 Aug 2021
      RRID:Addgene_61591

      DOI: 10.1016/j.celrep.2019.05.103

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      Curator: @ethanbadger

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      RRID:Addgene_61591 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124719307429
  49. Apr 2021
  50. www.sciencedirect.com www.sciencedirect.com
    Generation of a homozygous LRP2 knockout human embryonic stem cell line (FDCHDPe010-A-56) by CRISPR/Cas9 system
    1
    1. scibot 09 Apr 2021
      Addgene_61591

      DOI: 10.1016/j.scr.2021.102342

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      RRIDCUR:Validated RRID:Addgene_61591
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    sciencedirect.com/science/article/pii/S1873506121001884
  51. Sep 2020
  52. www.jneurosci.org www.jneurosci.org
    Dopaminergic signaling in the nucleus accumbens modulates stress-coping strategies during inescapable stress
    1
    1. scibot 26 Sep 2020
      plasmid_61591

      DOI: 10.1523/JNEUROSCI.0444-20.2020

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    jneurosci.org/content/40/38/7241
  53. www.sciencedirect.com www.sciencedirect.com
    The Raphe Dopamine System Controls the Expression of Incentive Memory
    1
    1. scibot 23 Sep 2020
      RRID:Addgene_61591

      DOI: 10.1016/j.neuron.2020.02.009

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    sciencedirect.com/science/article/pii/S0896627320301082
  54. Jan 2020
  55. www.sciencedirect.com www.sciencedirect.com
    Programmable RNA-Guided RNA Effector Proteins Built from Human Parts
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_61591

      DOI: 10.1016/j.cell.2019.05.049

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      RRID:Addgene_61591 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867419306208