19 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Core passive and facultative mTOR-mediated mechanisms coordinate mammalian protein synthesis and decay
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    sciencedirect.com:5037/science/article/pii/S2405471225002893
  3. Nov 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multi-omic phenotyping of iPSC-derived neurons harboring the MAPT V337M mutation reveals tau hypophosphorylation and perturbed axon morphology pathways
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    pmc.ncbi.nlm.nih.gov/articles/PMC11185762/
  5. Aug 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bidirectional regulation of glycoprotein nonmetastatic melanoma protein B by β-glucocerebrosidase deficiency in GBA1 isogenic dopaminergic neurons from a patient with Gaucher disease and parkinsonism
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    pmc.ncbi.nlm.nih.gov/articles/PMC12262256/
  7. Jul 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combining light-induced aggregation and biotin proximity labeling implicates endolysosomal proteins in early α-synuclein oligomerization
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    pmc.ncbi.nlm.nih.gov/articles/PMC12221657/
  9. Jun 2025
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNA-binding proteins DND1 and NANOS3 cooperatively suppress the entry of germ cell lineage
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    pmc.ncbi.nlm.nih.gov/articles/PMC12102168/
  11. May 2025
  12. www.sciencedirect.com www.sciencedirect.com
    IGF2BP1 restricts the induction of human primordial germ cell fate in an m6A-dependent manner
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    sciencedirect.com/science/article/pii/S193459092500181X
  13. Mar 2025
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Large-scale CRISPRi screens link metabolic stress to glioblastoma chemoresistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC11887098/
  15. www.nature.com www.nature.com
    Comparative characterization of human accelerated regions in neurons
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    nature.com/articles/s41586-025-08622-x
  16. Feb 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    C-terminal amides mark proteins for degradation via SCF–FBXO31
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    pmc.ncbi.nlm.nih.gov/articles/PMC11821526/
  18. Dec 2024
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Distinct differentiation trajectories leave lasting impacts on gene regulation and function of V2a interneurons
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    pmc.ncbi.nlm.nih.gov/articles/PMC11642877/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Prion protein pathology in Ubiquilin 2 models of ALS
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    pmc.ncbi.nlm.nih.gov/articles/PMC11651290/
  21. Jun 2024
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapeutic validation of MMR-associated genetic modifiers in a human ex vivo model of Huntington disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC11179424/
  23. May 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of quantitative high-throughput screening assays to identify, validate, and optimize small-molecule stabilizers of misfolded β-glucocerebrosidase with therapeutic potential for Gaucher disease and Parkinson’s disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC11071283/
  25. Apr 2024
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of genetic modifiers enhancing B7-H3-targeting CAR T cell therapy against glioblastoma through large-scale CRISPRi screening
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    ncbi.nlm.nih.gov/pmc/articles/PMC10986136/
  27. Feb 2024
  28. link.springer.com link.springer.com
    Targeted CRISPR activation is functional in engineered human pluripotent stem cells but undergoes silencing after differentiation into cardiomyocytes and endothelium
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    link.springer.com/article/10.1007/s00018-023-05101-2
  29. Jun 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Comparative landscape of genetic dependencies in human and chimpanzee stem cells
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    sciencedirect.com/science/article/pii/S0092867423005950
  31. Dec 2022
  32. www.sciencedirect.com www.sciencedirect.com
    Generation of AAVS1 and CLYBL STRAIGHT-IN v2 acceptor human iPSC lines for integrating DNA payloads
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    sciencedirect.com/science/article/pii/S1873506122003403
  33. Jul 2022
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8254803/
  35. Mar 2021
  36. www.sciencedirect.com www.sciencedirect.com
    Transcriptional Programming of Human Mechanosensory Neuron Subtypes from Pluripotent Stem Cells
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    sciencedirect.com/science/article/pii/S221112471931719X