41 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A multiplexed gRNA piggyBac transposon system facilitates efficient induction of CRISPRi and CRISPRa in human pluripotent stem cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC6971260/
  3. Jun 2026
  4. www.sciencedirect.com www.sciencedirect.com
    GRHL and PGR control WNT4 expression via 3D looping of conserved and species-specific enhancers
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    sciencedirect.com/science/article/pii/S2211124726006534
  5. Apr 2026
  6. www.sciencedirect.com www.sciencedirect.com
    Cellular-state control using ribozyme-scaffolded miRNA-sensing and CRISPR-mediated actuation
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    sciencedirect.com/science/article/pii/S2667237526000792
  7. Feb 2026
  8. www.biorxiv.org www.biorxiv.org
    X-CODE: a dual RNA barcoding system for multi-platform clonal tracking and spatial phenotyping
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    biorxiv.org/content/10.64898/2026.02.10.705126v1
  9. Nov 2025
  10. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004225023016-main-html.html
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    54.241.53.176/2dc2795dad89007f55257c4b18d6264229fd76eb/1-s2.0-S2589004225023016-main-html.html
  11. Sep 2025
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Programmable solid-state condensates for spatiotemporal control of mammalian gene expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12394073/
  13. Aug 2025
  14. www.biorxiv.org www.biorxiv.org
    Inhibition of BRN2 in Melanoma Reverses Anoikis Resistance and Sensitizes Cells to Killing by Vemurafenib
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    biorxiv.org/content/10.1101/2025.07.31.667908v1
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Specific modulation of CRISPR transcriptional activators through RNA-sensing guide RNAs in mammalian cells and zebrafish embryos
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    pmc.ncbi.nlm.nih.gov/articles/PMC12306969/
  16. Jul 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SWITCHER, a CRISPR-inducible floxed wild-type Cre regulating CRISPR activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12214773/
  18. Jun 2025
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pre-existing DNA methylation signatures in the prefrontal cortex of alcohol-naïve nonhuman primates define neural vulnerability for future risky ethanol consumption
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    pmc.ncbi.nlm.nih.gov/articles/PMC12044430/
  20. May 2025
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MCRS1 sensitizes T cell–dependent immunotherapy by augmenting MHC-I expression in solid tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11572484/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Increasing H2B Monoubiquitination Improves the Transcriptome and Memory in the Aged Hippocampus
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    pmc.ncbi.nlm.nih.gov/articles/PMC11998965/
  23. Apr 2025
  24. www.pnas.org www.pnas.org
    Next-generation CRISPR/Cas9 transcriptional activation in Drosophila using flySAM
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    pnas.org/doi/10.1073/pnas.1800677115
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Light-induced expression of gRNA allows for optogenetic gene editing of T lymphocytes in vivo
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    pmc.ncbi.nlm.nih.gov/articles/PMC11925727/
  26. Feb 2025
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transdermal microneedle-assisted ultrasound-enhanced CRISPRa system to enable sono-gene therapy for obesity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11811159/
  28. www.biorxiv.org www.biorxiv.org
    Bcl11b orchestrates subcerebral projection neuron axon development via cell-autonomous, non-cell-autonomous, and subcellular mechanisms
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    biorxiv.org/content/10.1101/2024.10.20.619265v1
  29. Jan 2025
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A trigger-inducible split-Csy4 architecture for programmable RNA modulation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11734699/
  31. Sep 2024
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extended replicative lifespan of primary resting T cells by CRISPR/dCas9-based epigenetic modifiers and transcriptional activators
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    ncbi.nlm.nih.gov/pmc/articles/PMC11408452/
  33. May 2024
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protocol to target a promoter region in human embryonic kidney cells using the CRISPR-dCas9 system for single-locus proteomics
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    ncbi.nlm.nih.gov/pmc/articles/PMC11070752/
  35. Apr 2024
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The tumor suppressor p53 is a negative regulator of the carcinoma-associated transcription factor FOXQ1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10981115/
  37. Mar 2024
  38. www.biorxiv.org www.biorxiv.org
    Enhancer-targeted CRISPR-Activation Rescues Haploinsufficient Autism Susceptibility Genes
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    biorxiv.org/content/10.1101/2024.03.13.584921v1
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tick hemocytes have a pleiotropic role in microbial infection and arthropod fitness
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    ncbi.nlm.nih.gov/pmc/articles/PMC10923820/
  40. Feb 2024
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gesicles packaging dCas9-VPR ribonucleoprotein complexes can combine with vorinostat and promote HIV proviral transcription
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    ncbi.nlm.nih.gov/pmc/articles/PMC10881426/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Logical design of synthetic cis-regulatory DNA for genetic tracing of cell identities and state changes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10844330/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanosensitive super-enhancers regulate genes linked to atherosclerosis in endothelial cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10794123/
  44. Sep 2023
  45. www.sciencedirect.com www.sciencedirect.com
    Hypoxic regulation of hypoxia inducible factor 1 alpha via antisense transcription
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    sciencedirect.com/science/article/pii/S0021925823023190
  46. Apr 2023
  47. www.biorxiv.org www.biorxiv.org
    Distinct roles of Bdnf I and Bdnf IV transcript variant expression in hippocampal neurons
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    biorxiv.org/content/10.1101/2023.04.05.535694v1
  48. Jun 2022
  49. www.nature.com www.nature.com
    Control of CRK-RAC1 activity by the miR-1/206/133 miRNA family is essential for neuromuscular junction function
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    nature.com/articles/s41467-022-30778-7
  50. Jan 2022
  51. www.science.org www.science.org
    Four-dimensional nuclear speckle phase separation dynamics regulate proteostasis
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    science.org/doi/10.1126/sciadv.abl4150
  52. Aug 2021
  53. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
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    onlinelibrary.wiley.com/doi/full/10.1002/jcp.28727
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6318322/
  55. www.sciencedirect.com www.sciencedirect.com
    The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer
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    sciencedirect.com/science/article/pii/S1535610821003846
  56. Nov 2020
  57. www.sciencedirect.com www.sciencedirect.com
    Generation of PAX7 Reporter Cells to Investigate Skeletal Myogenesis from Human Pluripotent Stem Cells
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    sciencedirect.com/science/article/pii/S2666166720301453
  58. Oct 2020
  59. www.sciencedirect.com www.sciencedirect.com
    A CRISPR-strategy for the generation of a detectable fluorescent hESC reporter line (WAe009-A-37) for the subpallial determinant GSX2
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    sciencedirect.com/science/article/pii/S1873506120303172
  60. Sep 2020
  61. www.nature.com www.nature.com
    Genome editing in primary cells and in vivo using viral-derived Nanoblades loaded with Cas9-sgRNA ribonucleoproteins
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    nature.com/articles/s41467-018-07845-z
  62. www.sciencedirect.com www.sciencedirect.com
    A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells
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    sciencedirect.com/science/article/pii/S1934590920301569
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The COMET toolkit for composing customizable genetic programs in mammalian cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC7005830/
  64. Jan 2020
  65. link.springer.com link.springer.com
    Targeted regulation of fibroblast state by CRISPR-mediated CEBPA expression
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    link.springer.com/article/10.1186/s12931-019-1253-1
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Neuron-Optimized CRISPR/dCas9 Activation System for Robust and Specific Gene Regulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC6412672/