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Oct 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Genome-scale CRISPR/Cas9 screen determines factors modulating sensitivity to ProTide NUC-1031

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1. scibot 28 Oct 2026
  
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  DOI: 10.1038/s41598-019-44089-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC6529431/
Jun 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

dCas9-metabolic enzyme fusions modulate global and locus-specific gene expression

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  DOI: 10.64898/2026.05.10.724078
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13174488/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Kv2–VAP interactions enhance presynaptic ER and mitochondrial calcium influx and the mobilization of vesicles from the reserve pool

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1. scibot 06 Jun 2026
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13174469/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Improved vector toolkit for genome writing in mammalian cells

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1. scibot 06 Jun 2026
  
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  plasmid_64073
  
  DOI: 10.64898/2026.03.15.711894
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13015416/
Apr 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A GABAergic network from AVP- to VIP-neurons in the suprachiasmatic nucleus sets the timing of circadian behavior rhythms

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1. scibot 08 Apr 2026
  
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  DOI: 10.1371/journal.pbio.3003706
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12991363/
Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The origin of hepatocellular carcinoma depends on metabolic zonation

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1. scibot 21 Mar 2026
  
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  DOI: 10.1126/science.adv7129
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12999168/
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

FTO inhibition attenuates renal fibrosis by downregulating ferroptosis activator ACSL4 and profibrotic factor TGFBI

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1. scibot 23 Nov 2025
  
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  DOI: 10.1016/j.isci.2025.113515
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12494575/
www.science.org www.science.org

The origin of hepatocellular carcinoma depends on metabolic zonation

1
1. scibot 11 Nov 2025
  
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science.org/doi/10.1126/science.adv7129
Oct 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

An Autochthonous Model of Lung Cancer Identifies Requirements for Cellular Transformation in the Naked Mole-Rat

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1. scibot 03 Oct 2025
  
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  RRID:Addgene_64073
  
  DOI: 10.1158/2159-8290.CD-25-0526
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12486303/
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

FTO inhibition attenuates renal fibrosis by downregulating ferroptosis activator ACSL4 and profibrotic factor TGFBI

1
1. scibot 23 Sep 2025
  
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  Addgene_64073
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12494575/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Composition and RNA binding specificity of metazoan RNase MRP

2
1. scibot 06 Sep 2025
  
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  64073
  
  DOI: 10.1093/nar/gkaf829
  
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2. scibot 06 Sep 2025
  
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  64073
  
  DOI: 10.1093/nar/gkaf829
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12390755/
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Divergent DNA methylation dynamics in marsupial and eutherian embryos

1
1. scibot 20 Jul 2025
  
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  DOI: 10.1038/s41586-025-08992-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12221971/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Reversible proliferative arrest induced by rapid depletion of RNase MRP

1
1. scibot 20 Jul 2025
  
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  64073
  
  DOI: 10.1038/s41467-025-60471-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12177063/
www.tandfonline.com www.tandfonline.com

Production of immune receptor knockout chickens via direct in vivo transfection of primordial germ cells

1
1. scibot 01 Jul 2025
  
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  RRID:Addgene_64073
  
  DOI: 10.1080/10495398.2025.2523027
  
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tandfonline.com/doi/abs/10.1080/10495398.2025.2523027
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Tumor-derived erythropoietin acts as an immunosuppressive switch in cancer immunity

1
1. scibot 15 Jun 2025
  
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  plasmid_64073
  
  DOI: 10.1126/science.adr3026
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12110762/
May 2025
www.sciencedirect.com www.sciencedirect.com

KDM3A and KDM3B regulate alternative splicing in mouse pluripotent stem cells

2
1. scibot 29 May 2025
  
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  Plasmid#64073
  
  DOI: 10.1016/j.isci.2025.112612
  
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2. scibot 29 May 2025
  
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  Addgene_64073
  
  DOI: 10.1016/j.isci.2025.112612
  
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sciencedirect.com/science/article/pii/S2589004225008739
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Composition and RNA binding specificity of metazoan RNase MRP

1
1. scibot 11 Mar 2025
  
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  64073
  
  DOI: 10.1101/2025.02.21.639568
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11870539/
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Systematic identification of Y-chromosome gene functions in mouse spermatogenesis

1
1. scibot 11 Feb 2025
  
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  Addgene_64073
  
  DOI: 10.1126/science.ads6495
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7617377/
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Human TRMT1 and TRMT1L paralogs ensure the proper modification state, stability, and function of tRNAs

1
1. scibot 09 Jan 2025
  
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  RRID:Addgene_64073
  
  DOI: 10.1016/j.celrep.2024.115092
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11831618/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Patient-derived response estimates from zero-passage organoids of luminal breast cancer

1
1. scibot 04 Jan 2025
  
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  Addgene, #64073
  
  DOI: 10.1186/s13058-024-01931-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11687200/
Dec 2024
elifesciences.org elifesciences.org

Telomere length sensitive regulation of interleukin receptor 1 type 1 (IL1R1) by the shelterin protein TRF2 modulates immune signalling in the tumour microenvironment

1
1. scibot 29 Dec 2024
  
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  DOI: 10.7554/eLife.95106
  
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elifesciences.org/articles/95106
Aug 2024
www.biorxiv.org www.biorxiv.org

Systematic identification of Y-chromosome gene functions in mouse spermatogenesis

1
1. scibot 20 Aug 2024
  
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  Addgene #64073
  
  DOI: 10.1101/2024.07.18.604063
  
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biorxiv.org/content/10.1101/2024.07.18.604063v1
Jul 2024
www.sciencedirect.com www.sciencedirect.com

Lack of mismatch repair enhances resistance to methylating agents for cells deficient in oxidative demethylation

1
1. scibot 24 Jul 2024
  
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  plasmid 64073; Addgene
  
  DOI: 10.1016/j.jbc.2024.107492
  
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sciencedirect.com/science/article/pii/S0021925824019938
www.cell.com www.cell.com

Shifts in keratin isoform expression activate motility signals during wound healing

1
1. scibot 19 Jul 2024
  
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  DOI: 10.1016/j.devcel.2024.06.011
  
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cell.com/developmental-cell/abstract/S1534-5807(24)00389-7
www.cell.com www.cell.com

A non-canonical role for a small nucleolar RNA in ribosome biogenesis and senescence

1
1. scibot 11 Jul 2024
  
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  RRID:Addgene_64073
  
  DOI: 10.1016/j.cell.2024.06.019
  
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cell.com/cell/fulltext/S0092-8674(24)00693-7
Jun 2024
www.sciencedirect.com www.sciencedirect.com

De novo and salvage purine synthesis pathways across tissues and tumors

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1. scibot 04 Jun 2024
  
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  Addgene64073
  
  DOI: 10.1016/j.cell.2024.05.011
  
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  RRID:Addgene_64073 DOI:10.1016/j.cell.2024.05.011
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sciencedirect.com/science/article/pii/S0092867424005208
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Patient-derived response estimates from zero-passage organoids of luminal breast cancer

1
1. scibot 23 Apr 2024
  
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  64073
  
  DOI: 10.1101/2024.03.24.586432
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10996455/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

KDM3A and KDM3B Maintain Naïve Pluripotency Through the Regulation of Alternative Splicing

1
1. scibot 13 Feb 2024
  
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  Addgene_64073
  
  DOI: 10.1101/2023.05.31.543088
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10312572/
Dec 2023
www.nature.com www.nature.com

Downstream STING pathways IRF3 and NF-κB differentially regulate CCL22 in response to cytosolic dsDNA

1
1. scibot 01 Dec 2023
  
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  RRID:Addgene_64073
  
  DOI: 10.1038/s41417-023-00678-z
  
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nature.com/articles/s41417-023-00678-z
Sep 2023
www.sciencedirect.com www.sciencedirect.com

TOBF1 modulates mouse embryonic stem cell fate through regulating alternative splicing of pluripotency genes

1
1. scibot 30 Sep 2023
  
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  RRID:Addgene_64073
  
  DOI: 10.1016/j.celrep.2023.113177
  
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  Curator: @jmitrevska
  
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sciencedirect.com/science/article/pii/S2211124723011890
Mar 2023
www.sciencedirect.com www.sciencedirect.com

In vivo interrogation of regulatory genomes reveals extensive quasi-insufficiency in cancer evolution

1
1. scibot 11 Mar 2023
  
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  RRID:Addgene_64073
  
  DOI: 10.1016/j.xgen.2023.100276
  
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sciencedirect.com/science/article/pii/S2666979X23000368
Oct 2022
www.sciencedirect.com www.sciencedirect.com

In situ cell-type-specific cell-surface proteomic profiling in mice

1
1. scibot 11 Oct 2022
  
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  RRID:Addgene_64073
  
  DOI: 10.1016/j.neuron.2022.09.025
  
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sciencedirect.com/science/article/pii/S0896627322008649
Aug 2022
www.sciencedirect.com www.sciencedirect.com

Microglia contribute to the postnatal development of cortical somatostatin-positive inhibitory cells and to whisker-evoked cortical activity

1
1. scibot 17 Aug 2022
  
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  RRID:Addgene_64073
  
  DOI: 10.1016/j.celrep.2022.111209
  
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sciencedirect.com/science/article/pii/S2211124722010269
www.sciencedirect.com www.sciencedirect.com

Vasopressin neurons in the paraventricular hypothalamus promote wakefulness via lateral hypothalamic orexin neurons

1
1. scibot 02 Aug 2022
  
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  plasmid_64073
  
  DOI: 10.1016/j.cub.2022.07.020
  
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sciencedirect.com/science/article/pii/S0960982222011216
Jan 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CRISPR-Mediated Knockout of Long 3′ UTR mRNA Isoforms in mESC-Derived Neurons

1
1. scibot 05 Jan 2022
  
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  RRID:Addgene_64073
  
  DOI: 10.3389/fgene.2021.789434
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8718760/
Nov 2021
www.sciencedirect.com www.sciencedirect.com

CRISPR-Cas9 Mediated Exonic Disruption for HIV-1 Elimination

1
1. scibot 11 Nov 2021
  
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  Addgene_64073
  
  DOI: 10.1016/j.ebiom.2021.103678
  
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sciencedirect.com/science/article/pii/S2352396421004722
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 31 Jul 2021
  
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  plasmid_64073
  
  DOI: 10.7554/eLife.40556
  
  Resource: RRID:Addgene_64073
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_64073
  
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  RRID:Addgene_64073 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC6301792/
Mar 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

An optimized CRISPR/Cas9 approach for precise genome editing in neurons

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1. scibot 17 Mar 2021
  
  in Public
  
  plasmid_64073
  
  DOI: 10.7554/eLife.65202
  
  Resource: RRID:Addgene_64073
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_64073
  
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  RRIDCUR:Validated RRID:Addgene_64073
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ncbi.nlm.nih.gov/pmc/articles/PMC7946428/
Feb 2021
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GluD2- and Cbln1-mediated competitive interactions shape the dendritic arbors of cerebellar Purkinje cells

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1. scibot 28 Feb 2021
  
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  RRID:Addgene_64073
  
  DOI: 10.1016/j.neuron.2020.11.028
  
  Resource: RRID:Addgene_64073
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S0896627320309338
elifesciences.org elifesciences.org

Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development

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1. scibot 11 Feb 2021
  
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  RRID:Addgene_64073
  
  DOI: 10.7554/eLife.59067
  
  Resource: RRID:Addgene_64073
  
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  RRIDCUR:Validated RRID:Addgene_64073
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elifesciences.org/articles/59067
Sep 2020
www.cell.com www.cell.com

Design and Testing of Vector-Producing HEK293T Cells Bearing a Genomic Deletion of the SV40 T Antigen Coding Region

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1. scibot 06 Sep 2020
  
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  RRID:Addgene_64073
  
  DOI: 10.1016/j.omtm.2020.07.006
  
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  Curator: @evieth
  
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  RRID:Addgene_64073 RRIDCUR:Validated
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cell.com/molecular-therapy-family/methods/abstract/S2329-0501(20)30155-8
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High-Resolution In Vivo Identification of miRNA Targets by Halo-Enhanced Ago2 Pull-Down

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1. scibot 04 Sep 2020
  
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  Addgene: 64073
  
  DOI: 10.1016/j.molcel.2020.05.009
  
  Resource: RRID:Addgene_64073
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_64073
  
  Curator comments: pX333
  
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  RRID:Addgene_64073 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1097276520303105
Jan 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 13 Jan 2020
  
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  plasmid_64073
  
  DOI: 10.7554/eLife.40556
  
  Resource: RRID:Addgene_64073
  
  Curator: @evieth
  
  SciCrunch record: plasmid_64073
  
  What is this?
  
  RRID:Addgene_64073 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC6301792/