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  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Engineered transcription-associated Cas9 targeting in eukaryotic cells
    1
    1. scibot 21 Dec 2024
      RRID:Addgene_65777

      DOI: 10.1038/s41467-024-54629-9

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    pmc.ncbi.nlm.nih.gov/articles/PMC11603292/
  3. Dec 2024
  4. www.nature.com www.nature.com
    Glucose limitation protects cancer cells from apoptosis induced by pyrimidine restriction and replication inhibition
    1
    1. scibot 06 Dec 2024
      RRID:Addgene_65777

      DOI: 10.1038/s42255-024-01166-w

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    nature.com/articles/s42255-024-01166-w
  5. www.sciencedirect.com www.sciencedirect.com
    Long-term in vitro expansion of a human fetal pancreas stem cell that generates all three pancreatic cell lineages
    1
    1. scibot 03 Dec 2024
      Addgene_65777

      DOI: 10.1016/j.cell.2024.10.044

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    sciencedirect.com/science/article/pii/S0092867424012546
  6. Nov 2024
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Engineered transcription-associated Cas9 targeting in eukaryotic cells
    1
    1. scibot 19 Nov 2024
      RRID:Addgene_65777

      DOI: 10.1101/2023.09.18.558319

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    pmc.ncbi.nlm.nih.gov/articles/PMC10541143/
  8. Sep 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ISGylation enhances dsRNA-induced interferon response and NFκB signaling in fallopian tube epithelial cells
    1
    1. scibot 27 Sep 2024
      65777

      DOI: 10.1016/j.jbc.2024.107686

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    ncbi.nlm.nih.gov/pmc/articles/PMC11418117/
  10. www.sciencedirect.com www.sciencedirect.com
    Modeling the atrioventricular conduction axis using human pluripotent stem cell-derived cardiac assembloids
    1
    1. scibot 11 Sep 2024
      RRID:Addgene_65777

      DOI: 10.1016/j.stem.2024.08.008

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    sciencedirect.com/science/article/pii/S1934590924002947
  11. www.sciencedirect.com www.sciencedirect.com
    Base editing of the GLB1 gene is therapeutic in GM1 gangliosidosis patient-derived cells
    1
    1. scibot 10 Sep 2024
      RRID:Addgene_65777

      DOI: 10.1016/j.ymgme.2024.108568

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    sciencedirect.com/science/article/pii/S1096719224004529
  12. Aug 2024
  13. www.sciencedirect.com www.sciencedirect.com
    The FXR1 network acts as a signaling scaffold for actomyosin remodeling
    1
    1. scibot 19 Aug 2024
      Addgene_65777

      DOI: 10.1016/j.cell.2024.07.015

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    sciencedirect.com/science/article/pii/S009286742400775X
  14. Jul 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Base editing rescues acid α-glucosidase function in infantile-onset Pompe disease patient-derived cells
    1
    1. scibot 01 Jul 2024
      RRID:Addgene_65777

      DOI: 10.1016/j.omtn.2024.102220

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    ncbi.nlm.nih.gov/pmc/articles/PMC11214518/
  16. Jun 2024
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multimodal framework to resolve variants of uncertain significance in TSC2
    1
    1. scibot 27 Jun 2024
      plasmid_65777

      DOI: 10.1101/2024.06.07.597916

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    ncbi.nlm.nih.gov/pmc/articles/PMC11185720/
  18. Apr 2024
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Splice modulators target PMS1 to reduce somatic expansion of the Huntington’s disease-associated CAG repeat
    1
    1. scibot 18 Apr 2024
      plasmid_65777

      DOI: 10.1038/s41467-024-47485-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC11015039/
  20. Mar 2024
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In situ architecture of Opa1-dependent mitochondrial cristae remodeling
    1
    1. scibot 01 Mar 2024
      65777

      DOI: 10.1038/s44318-024-00027-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC10897290/
  22. Feb 2024
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Generation of Human Isogenic Induced Pluripotent Stem Cell Lines with CRISPR Prime Editing
    1
    1. scibot 29 Feb 2024
      Addgene_65777

      DOI: 10.1089/crispr.2023.0066

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    ncbi.nlm.nih.gov/pmc/articles/PMC10880268/
  24. www.biorxiv.org www.biorxiv.org
    iSCORE-PD: an isogenic stem cell collection to research Parkinson’s Disease
    1
    1. scibot 22 Feb 2024
      RRID:Addgene_65777

      DOI: 10.1101/2024.02.12.579917

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    biorxiv.org/content/10.1101/2024.02.12.579917v1
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Benzomorphan and non-benzomorphan agonists differentially alter sigma-1 receptor quaternary structure, as does types of cellular stress
    1
    1. scibot 08 Feb 2024
      plasmid_65777

      DOI: 10.1007/s00018-023-05023-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC10774196/
  26. Sep 2023
  27. www.sciencedirect.com www.sciencedirect.com
    Base editing corrects the common Salla disease SLC17A5 c.115C>T variant
    1
    1. scibot 16 Sep 2023
      RRID:Addgene_65777

      DOI: 10.1016/j.omtn.2023.08.024

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    sciencedirect.com/science/article/pii/S2162253123002354
  28. Aug 2023
  29. 52.53.155.43 52.53.155.43
    One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids
    1
    1. scibot 24 Aug 2023
      plasmid_65777

      DOI: 10.1038/s41467-023-40701-3

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    52.53.155.43/6be832dffc5b1bbf8ca7ed6df051bba72a6ab6af/s41467-023-40701-3-html.html
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PMS1 as a target for splice modulation to prevent somatic CAG repeat expansion in Huntington’s disease
    1
    1. scibot 16 Aug 2023
      plasmid_65777

      DOI: 10.1101/2023.07.25.550489

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    ncbi.nlm.nih.gov/pmc/articles/PMC10402039/
  31. May 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Generation of three CRISPR/Cas9 edited human induced pluripotent stem cell lines (DHMi005-A-5, DHMi005-A-6 and DHMi005-A-7) carrying a Holt-Oram Syndrome patient-specific TBX5 mutation with known cardiac phenotype and a FLAG-tag after exon 9 of the TBX5 gene
    1
    1. scibot 17 May 2023
      RRID:Addgene_65777

      DOI: 10.1016/j.scr.2023.103123

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    sciencedirect.com/science/article/pii/S1873506123001095
  33. Apr 2023
  34. www.biorxiv.org www.biorxiv.org
    Computationally Engineered CRISPR-SpyCas9 High-Fidelity Variants with Improved Specificity and Reduced Non-specific DNA Damage
    1
    1. scibot 20 Apr 2023
      RRID:Addgene_65777

      DOI: 10.1101/2023.04.11.536265

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    biorxiv.org/content/10.1101/2023.04.11.536265v1
  35. Jan 2023
  36. journals.plos.org journals.plos.org
    In vitro genome editing activity of Cas9 in somatic cells after random and transposon-based genomic Cas9 integration
    1
    1. scibot 04 Jan 2023
      RRID:Addgene_65777

      DOI: 10.1371/journal.pone.0279123

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    journals.plos.org/plosone/article
  37. Dec 2022
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel intergenic enhancer that regulates Bdnf expression in developing cortical neurons
    1
    1. scibot 30 Dec 2022
      Addgene 65777

      DOI: 10.1016/j.isci.2022.105695

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    ncbi.nlm.nih.gov/pmc/articles/PMC9792897/
  39. Oct 2022
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Highly efficient generation of isogenic pluripotent stem cell models using prime editing
    1
    1. scibot 25 Oct 2022
      RRID:Addgene_65777

      DOI: 10.7554/eLife.79208

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    ncbi.nlm.nih.gov/pmc/articles/PMC9584603/
  41. Jan 2022
  42. www.sciencedirect.com www.sciencedirect.com
    Generation of a CRISPR/Cas edited human induced pluripotent stem cell line DHMi005-A-1 carrying a patient-specific disease-causing point mutation in the TBX5 gene
    2
    1. scibot 28 Jan 2022
      Addgene #65777

      DOI: 10.1016/j.scr.2022.102691

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      Curator: @sophiastull

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    2. scibot 28 Jan 2022
      Addgene_65777

      DOI: 10.1016/j.scr.2022.102691

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    sciencedirect.com/science/article/pii/S187350612200040X
  43. Dec 2020
  44. www.sciencedirect.com www.sciencedirect.com
    Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q
    1
    1. scibot 17 Dec 2020
      BPK1520

      DOI: 10.1016/j.celrep.2020.108493

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    sciencedirect.com/science/article/pii/S2211124720314820