32 Matching Annotations
  1. Mar 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mechanisms of resistance to VHL loss-induced genetic and pharmacological vulnerabilities
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    pmc.ncbi.nlm.nih.gov/articles/PMC12905196/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A genome-scale single-cell CRISPRi map of trans gene regulation across human pluripotent stem cell lines
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    pmc.ncbi.nlm.nih.gov/articles/PMC12903452/
  4. Feb 2026
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of CTLH component MAEA impairs DNA repair and replication and leads to developmental delay
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    pmc.ncbi.nlm.nih.gov/articles/PMC12905269/
  6. Jan 2026
  7. www.sciencedirect.com www.sciencedirect.com
    CRISPR screens in the context of immune selection identify CHD1 and MAP3K7 as mediators of cancer immunotherapy resistance
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    sciencedirect.com/science/article/pii/S266637912500638X
  8. Dec 2025
  9. www.nature.com www.nature.com
    A next-generation dual guide CRISPR system for genetic interaction library screening
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    nature.com/articles/s41467-025-67256-9
  10. Nov 2025
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A histone-centric multi-omics study shows that increased H3K4 methylation sustains triple-negative breast cancer phenotypes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12484688/
  12. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004225022382-main-html.html
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    54.241.53.176/1f0314c56ee274d7cfb4f962c2645407e5cadc04/1-s2.0-S2589004225022382-main-html.html
  13. Sep 2025
  14. www.sciencedirect.com www.sciencedirect.com
    Tumor suppressor protein p53 governs human trophoblast lineage development
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    sciencedirect.com/science/article/pii/S2211124725010812
  15. Aug 2025
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The synthetic lethal interaction between CDS1 and CDS2 is a vulnerability in uveal melanoma and across multiple tumor types
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    pmc.ncbi.nlm.nih.gov/articles/PMC12283370/
  17. Jun 2025
  18. www.sciencedirect.com www.sciencedirect.com
    CRAMP1 drives linker histone expression to enable Polycomb repression
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    sciencedirect.com/science/article/pii/S1097276525004708
  19. May 2025
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    METTL3-dependent m6A RNA methylation regulates transposable elements and represses human naïve pluripotency through transposable element-derived enhancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC12038396/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Vibrio MARTX toxin binding of biantennary N-glycans at host cell surfaces
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    pmc.ncbi.nlm.nih.gov/articles/PMC11980833/
  22. www.nature.com www.nature.com
    Establishment of human expanded potential stem cell lines via preimplantation embryo cultivation and somatic cell reprogramming
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    nature.com/articles/s41596-025-01168-2
  23. Mar 2025
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Guanine nucleotide biosynthesis blockade impairs MLL complex formation and sensitizes leukemias to menin inhibition
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11920272/
  25. Jan 2025
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of SMAD1 in acute myeloid leukemia with KMT2A::AFF1 and KMT2A::MLLT3 fusion genes
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    pmc.ncbi.nlm.nih.gov/articles/PMC11743462/
  27. www.sciencedirect.com www.sciencedirect.com
    OSMOTIC STRESS INFLUENCES MICROTUBULE DRUG RESPONSE VIA WNK1 KINASE SIGNALING
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    sciencedirect.com/science/article/pii/S1368764625000032
  28. Sep 2024
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PIIS2589004224017000-html.html
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    ncbi.nlm.nih.gov/pmc/articles/PMC11295705/
  30. Aug 2024
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Uncovering the role of TET2-mediated ENPEP activation in trophoblast cell fate determination
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11335190/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bhlhe40 Regulates Proliferation and Angiogenesis in Mouse Embryoid Bodies under Hypoxia
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    ncbi.nlm.nih.gov/pmc/articles/PMC11277088/
  33. Jul 2024
  34. www.sciencedirect.com www.sciencedirect.com
    Competition between two HUSH complexes orchestrates the immune response to retroelement invasion
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    sciencedirect.com/science/article/pii/S1097276524005276
  35. www.biorxiv.org www.biorxiv.org
    Osmotic Stress Influences Microtubule Drug Response Via WNK1 Kinase Signaling
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    biorxiv.org/content/10.1101/2024.07.08.602030v1
  36. Jun 2024
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Legionella pneumophila exploits the endo-lysosomal network for phagosome biogenesis by co-opting SUMOylated Rab7
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11115209/
  38. Apr 2024
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR screens identify the YAP/TEAD axis as a driver of persister cells in EGFR mutant lung cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11043391/
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR screens decode cancer cell pathways that trigger γδ T cell detection
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    ncbi.nlm.nih.gov/pmc/articles/PMC11003766/
  41. Feb 2024
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Validation of Candidate Host Cell Entry Factors for Bovine Herpes Virus Type-1 Based on a Genome-Wide CRISPR Knockout Screen
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    ncbi.nlm.nih.gov/pmc/articles/PMC10893506/
  43. www.biorxiv.org www.biorxiv.org
    New submission 03/10/2023, 09:01:17
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    biorxiv.org/content/10.1101/2023.08.31.555634v2
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    scSNV-seq: high-throughput phenotyping of single nucleotide variants by coupled single-cell genotyping and transcriptomics
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    ncbi.nlm.nih.gov/pmc/articles/PMC10789043/
  45. Oct 2023
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endocrine Therapy Synergizes with SMAC Mimetics to Potentiate Antigen Presentation and Tumor Regression in Hormone Receptor–Positive Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10543960/
  47. Mar 2023
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmaceutical Reactivation of Attenuated Apoptotic Pathways Leads to Elimination of Osimertinib Drug-Tolerant Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10035388/
  49. Feb 2023
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Base editing screens map mutations affecting interferon-γ signaling in cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9942875/
  51. Jan 2023
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Base editing screens map mutations affecting interferon-γ signaling in cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9942875/
  53. Nov 2021
  54. elifesciences.org elifesciences.org
    A functional genetic toolbox for human tissue-derived organoids
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    elifesciences.org/articles/67886