Hypothesis

8 Matching Annotations

Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeted deletions in human mitochondrial DNA engineered by Type V CRISPR–Cas12a system

1
1. scibot 21 Nov 2025
  
  in Public
  
  69982
  
  DOI: 10.1093/narmme/ugaf021
  
  Resource: RRID:Addgene_69982
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_69982
  
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  RRID:Addgene_69982
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RRID:Addgene_69982

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12429949/
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Highly parallel profiling of the activities and specificities of Cas12a variants in human cells

1
1. scibot 07 Apr 2025
  
  in Public
  
  69982
  
  DOI: 10.1038/s41467-025-57150-9
  
  Resource: RRID:Addgene_69982
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_69982
  
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  RRID:Addgene_69982
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RRID:Addgene_69982

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC11953374/
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Rational engineering of minimally immunogenic nucleases for gene therapy

1
1. scibot 27 Jan 2025
  
  in Public
  
  Addgene_69982
  
  DOI: 10.1038/s41467-024-55522-1
  
  Resource: RRID:Addgene_69982
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_69982
  
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  RRID:Addgene_69982
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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC11696374/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Engineering of a compact, high-fidelity EbCas12a variant that can be packaged with its crRNA into an all-in-one AAV vector delivery system

1
1. scibot 13 Aug 2024
  
  in Public
  
  69982
  
  DOI: 10.1371/journal.pbio.3002619
  
  Resource: RRID:Addgene_69982
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_69982
  
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  RRID:Addgene_69982
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scibot

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ncbi.nlm.nih.gov/pmc/articles/PMC11139299/
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Engineering of Cas12a nuclease variants with enhanced genome-editing specificity

1
1. scibot 15 Apr 2024
  
  in Public
  
  69982
  
  DOI: 10.1371/journal.pbio.3002514
  
  Resource: RRID:Addgene_69982
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_69982
  
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  RRID:Addgene_69982
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ncbi.nlm.nih.gov/pmc/articles/PMC10965058/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Comparison of Cas12a and Cas9-mediated mutagenesis in tomato cells

1
1. scibot 28 Feb 2024
  
  in Public
  
  69982
  
  DOI: 10.1038/s41598-024-55088-4
  
  Resource: RRID:Addgene_69982
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_69982
  
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  RRID:Addgene_69982
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ncbi.nlm.nih.gov/pmc/articles/PMC10894265/
Oct 2020
www.cell.com www.cell.com

Phase Separation of Disease-Associated SHP2 Mutants Underlies MAPK Hyperactivation

1
1. scibot 01 Oct 2020
  
  in Public
  
  plasmid_69982
  
  DOI: 10.1016/j.cell.2020.09.002
  
  Resource: Addgene_69982
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_69982
  
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  RRID:Addgene_69982 RRIDCUR:Validated
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RRIDCUR:Validated

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scibot

URL

cell.com/cell/fulltext/S0092-8674(20)31143-0
Sep 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Human T Cells Expressing a CD19 CAR-T Receptor Provide Insights into Mechanisms of Human CD19-Positive β Cell Destruction

1
1. scibot 26 Sep 2020
  
  in Public
  
  pY010
  
  DOI: 10.1016/j.xcrm.2020.100097
  
  Resource: Addgene_69982
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_69982
  
  Curator comments: pY010 (pcDNA3.1-hAsCpf1)
  
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  RRIDCUR:Missing RRID:Addgene_69982
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RRIDCUR:Missing

RRID:Addgene_69982

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scibot

URL

pubmed.ncbi.nlm.nih.gov/33205073/