40 Matching Annotations
  1. Last 7 days
  2. www.biorxiv.org www.biorxiv.org
    Reduced SH3RF3 may protect against Alzheimer’s disease by lowering microglial pro-inflammatory responses via modulation of JNK and NFkB signaling
    1
    1. scibot 03 Jul 2024
      RRID:Addgene_71814

      DOI: 10.1101/2024.06.23.600281

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    biorxiv.org/content/10.1101/2024.06.23.600281v1
  3. www.nature.com www.nature.com
    PAM-flexible Engineered FnCas9 variants for robust and ultra-precise genome editing and diagnostics
    1
    1. scibot 01 Jul 2024
      71814

      DOI: 10.1038/s41467-024-49233-w

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    nature.com/articles/s41467-024-49233-w
  4. Jun 2024
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial Calcium Signaling Regulates Branched-Chain Amino Acid Catabolism in Fibrolamellar Carcinoma
    1
    1. scibot 15 Jun 2024
      71814

      DOI: 10.1101/2024.05.27.596106

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    ncbi.nlm.nih.gov/pmc/articles/PMC11160645/
  6. May 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD32 captures committed haemogenic endothelial cells during human embryonic development
    2
    1. scibot 19 May 2024
      Addgene_71814

      DOI: 10.1038/s41556-024-01403-0

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    2. scibot 19 May 2024
      Addgene_71814

      DOI: 10.1038/s41556-024-01403-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC11098737/
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KCTD Proteins Have Redundant Functions in Controlling Cellular Growth
    1
    1. scibot 12 May 2024
      Addgene_71814

      DOI: 10.3390/ijms25094993

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    ncbi.nlm.nih.gov/pmc/articles/PMC11084553/
  9. Apr 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons
    1
    1. scibot 16 Apr 2024
      AddgeneCat#71814; http://n2t.net/addgene:71814; RRID:Addgene_71814

      DOI: 10.1016/j.stem.2024.03.013

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    sciencedirect.com/science/article/pii/S1934590924000948
  11. Feb 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SpCas9-HF1 enhances accuracy of cell cycle-dependent genome editing by increasing HDR efficiency, and by reducing off-target effects and indel rates
    1
    1. scibot 13 Feb 2024
      plasmid_71814

      DOI: 10.1016/j.omtn.2024.102124

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    ncbi.nlm.nih.gov/pmc/articles/PMC10848011/
  13. link.springer.com link.springer.com
    CRISPR/Cas9-mediated deletion of a GA-repeat in human GPM6B leads to disruption of neural cell differentiation from NT2 cells
    1
    1. scibot 01 Feb 2024
      RRID:Addgene_71814

      DOI: 10.1038/s41598-024-52675-3

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    link.springer.com/article/10.1038/s41598-024-52675-3
  14. Jan 2024
  15. link.springer.com link.springer.com
    CRISPR/Cas9-mediated deletion of a GA-repeat in human GPM6B leads to disruption of neural cell differentiation from NT2 cells
    1
    1. scibot 30 Jan 2024
      RRID:Addgene_71814

      DOI: 10.1038/s41598-024-52675-3

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    link.springer.com/article/10.1038/s41598-024-52675-3
  16. Nov 2023
  17. link.springer.com link.springer.com
    The Development of SpCas9 Variants with High Specificity and Efficiency Based on the HH Theory
    1
    1. scibot 25 Nov 2023
      RRID:Addgene_71814

      DOI: 10.1134/S0026893324010187

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    link.springer.com/article/10.1134/S0026893324010187
  18. www.sciencedirect.com www.sciencedirect.com
    Unexpected extra exon skipping in the DYSF gene during restoring the reading frame by CRISPR/Cas9
    1
    1. scibot 17 Nov 2023
      RRID:Addgene_71814

      DOI: 10.1016/j.biosystems.2023.105072

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    sciencedirect.com/science/article/pii/S0303264723002472
  19. www.biorxiv.org www.biorxiv.org
    Systematic Dissection of Sequence Features Affecting the Binding Specificity of a Pioneer Factor Reveals Binding Synergy Between FOXA1 and AP-1
    1
    1. scibot 17 Nov 2023
      RRID:Addgene_71814

      DOI: 10.1101/2023.11.08.566246

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    biorxiv.org/content/10.1101/2023.11.08.566246v1
  20. Oct 2023
  21. www.sciencedirect.com www.sciencedirect.com
    Repurposing of glycine transport inhibitors for the treatment of erythropoietic protoporphyria
    1
    1. scibot 23 Oct 2023
      RRID:Addgene_71814

      DOI: 10.1016/j.chembiol.2021.02.021

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    sciencedirect.com/science/article/pii/S2451945621001069
  22. Sep 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Generating high-fidelity cochlear organoids from human pluripotent stem cells
    1
    1. scibot 29 Sep 2023
      Addgene_71814

      DOI: 10.1016/j.stem.2023.06.006

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    sciencedirect.com/science/article/pii/S1934590923002175
  24. May 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Differential cell-cycle control by oscillatory versus sustained Hes1 expression via p21
    1
    1. scibot 18 May 2023
      RRID:Addgene_71814

      DOI: 10.1016/j.celrep.2023.112520

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    sciencedirect.com/science/article/pii/S2211124723005314
  26. Apr 2023
  27. www.sciencedirect.com www.sciencedirect.com
    Deleting specific residues from the HNH linkers creates a CRISPR-SpCas9 variant with high fidelity and efficiency
    1
    1. scibot 29 Apr 2023
      RRID:Addgene_71814

      DOI: 10.1016/j.jbiotec.2023.04.008

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    sciencedirect.com/science/article/pii/S0168165623000809
  28. www.mdpi.com www.mdpi.com
    Bridging Gaps in HDR Improvement: The Role of MAD2L2, SCAI, and SCR7
    1
    1. scibot 08 Apr 2023
      RRID:Addgene_71814

      DOI: 10.3390/ijms24076704

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    mdpi.com/1422-0067/24/7/6704
  29. Jan 2023
  30. www.sciencedirect.com www.sciencedirect.com
    T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis
    1
    1. scibot 12 Jan 2023
      RRID:Addgene_71814

      DOI: 10.1016/j.immuni.2022.12.010

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    sciencedirect.com/science/article/pii/S107476132200646X
  31. currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com
    Determining On-Target, Off-Target, and Copy Number Status of Transgenic Events After CRISPR/Cas9 Targeted AAVS1 Safe-Harbor Modification of iPSCs Using Double-Control Quantitative Copy Number PCR
    1
    1. scibot 12 Jan 2023
      RRID:Addgene_71814

      DOI: 10.1002/cpz1.635

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    currentprotocols.onlinelibrary.wiley.com/doi/10.1002/cpz1.635
  32. link.springer.com link.springer.com
    The anti-estrogen receptor drug, tamoxifen, is selectively Lethal to P-glycoprotein-expressing Multidrug resistant tumor cells
    1
    1. scibot 07 Jan 2023
      RRID:Addgene_71814

      DOI: 10.1186/s12885-022-10474-x

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    link.springer.com/article/10.1186/s12885-022-10474-x
  33. Aug 2022
  34. www.sciencedirect.com www.sciencedirect.com
    Temporal control of PDGFRα regulates the fibroblast-to-myofibroblast transition in wound healing
    1
    1. scibot 17 Aug 2022
      Addgene_71814

      DOI: 10.1016/j.celrep.2022.111192

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    sciencedirect.com/science/article/pii/S2211124722010099
  35. Jun 2022
  36. www.researchsquare.com www.researchsquare.com
    Home
    1
    1. scibot 23 Jun 2022
      plasmid_71814

      DOI: 10.21203/rs.3.rs-658360/v1

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    researchsquare.com/article/rs-2787982/v1
  37. journals.plos.org journals.plos.org
    Investigating CRISPR/Cas9 gene drive for production of disease-preventing prion gene alleles
    1
    1. scibot 09 Jun 2022
      RRID:Addgene_71814

      DOI: 10.1371/journal.pone.0269342

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    journals.plos.org/plosone/article
  38. May 2022
  39. link.springer.com link.springer.com
    Rational Design of ssODN to Correct Mutations by Gene Editing
    1
    1. scibot 17 May 2022
      RRID:Addgene_71814

      DOI: 10.1134/S0006297922050078

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    link.springer.com/article/10.1134/S0006297922050078
  40. Apr 2022
  41. www.sciencedirect.com www.sciencedirect.com
    Knockout of P-glycoprotein abolish the collateral sensitivity of CHORC5 multidrug resistant cells
    1
    1. scibot 07 Apr 2022
      RRID:Addgene_71814

      DOI: 10.1016/j.bbrc.2022.03.148

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    sciencedirect.com/science/article/pii/S0006291X22004934
  42. Nov 2021
  43. elifesciences.org elifesciences.org
    A functional genetic toolbox for human tissue-derived organoids
    1
    1. scibot 05 Nov 2021
      plasmid_71814

      DOI: 10.7554/eLife.67886

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    elifesciences.org/articles/67886
  44. Oct 2021
  45. www.sciencedirect.com www.sciencedirect.com
    Tracing the emergence of primordial germ cells from bilaminar disc rabbit embryos and pluripotent stem cells
    1
    1. scibot 13 Oct 2021
      Plasmid_71814

      DOI: 10.1016/j.celrep.2021.109812

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    sciencedirect.com/science/article/pii/S2211124721012766
  46. Aug 2021
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 13 Aug 2021
      plasmid_71814

      DOI: 10.1016/j.molcel.2019.01.027

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    ncbi.nlm.nih.gov/pmc/articles/PMC6458999/
  48. www.sciencedirect.com www.sciencedirect.com
    CRISPR-Mediated Base Editing Enables Efficient Disruption of Eukaryotic Genes through Induction of STOP Codons
    1
    1. scibot 04 Aug 2021
      Plasmid_71814

      DOI: 10.1016/j.molcel.2017.08.008

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    sciencedirect.com/science/article/pii/S1097276517306056
  49. Jul 2021
  50. www.sciencedirect.com www.sciencedirect.com
    The E3 Ubiquitin Ligase Mind Bomb 1 Controls Adenovirus Genome Release at the Nuclear Pore Complex
    1
    1. scibot 31 Jul 2021
      Addgene #71814

      DOI: 10.1016/j.celrep.2019.11.064

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    sciencedirect.com/science/article/pii/S2211124719315554
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 28 Jul 2021
      plasmid_71814

      DOI: 10.1016/j.neuron.2017.10.008

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    ncbi.nlm.nih.gov/pmc/articles/PMC5851281/
  52. Jun 2021
  53. elifesciences.org elifesciences.org
    PHAROH lncRNA regulates Myc translation in hepatocellular carcinoma via sequestering TIAR
    1
    1. scibot 05 Jun 2021
      RRID:Addgene_71814

      DOI: 10.7554/eLife.68263

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    elifesciences.org/articles/68263
  54. Apr 2021
  55. www.sciencedirect.com www.sciencedirect.com
    FANCM regulates repair pathway choice at stalled replication forks
    1
    1. scibot 23 Apr 2021
      Addgene_71814

      DOI: 10.1016/j.molcel.2021.03.044

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    sciencedirect.com/science/article/pii/S1097276521002653
  56. www.sciencedirect.com www.sciencedirect.com
    Repurposing of glycine transport inhibitors for the treatment of erythropoietic protoporphyria
    1
    1. scibot 02 Apr 2021
      RRID:Addgene_71814

      DOI: 10.1016/j.chembiol.2021.02.021

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    sciencedirect.com/science/article/pii/S2451945621001069
  57. Jan 2021
  58. www.sciencedirect.com www.sciencedirect.com
    Critical Roles of Translation Initiation and RNA Uridylation in Endogenous Retroviral Expression and Neural Differentiation in Pluripotent Stem Cells
    1
    1. scibot 15 Jan 2021
      Addgene_71814

      DOI: 10.1016/j.celrep.2020.107715

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    sciencedirect.com/science/article/pii/S2211124720306926
  59. Dec 2020
  60. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    MAGE-A3 is a prognostic biomarker for poor clinical outcome in cutaneous squamous cell carcinoma with perineural invasion via modulation of cell proliferation
    1
    1. scibot 07 Dec 2020
      Addgene_71814

      DOI: 10.1371/journal.pone.0241551

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    pubmed.ncbi.nlm.nih.gov/33227008/
  61. Jan 2020
  62. www.sciencedirect.com www.sciencedirect.com
    Trans-Synaptic Signaling through the Glutamate Receptor Delta-1 Mediates Inhibitory Synapse Formation in Cortical Pyramidal Neurons
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_71814

      DOI: 10.1016/j.neuron.2019.09.027

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    sciencedirect.com/science/article/pii/S0896627319308013
  63. www.sciencedirect.com www.sciencedirect.com
    CD146 Regulates Growth Factor-Induced mTORC2 Activity Independent of the PI3K and mTORC1 Pathways
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_71814

      DOI: 10.1016/j.celrep.2019.09.047

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    sciencedirect.com/science/article/pii/S2211124719312355
  64. www.sciencedirect.com www.sciencedirect.com
    Esrrb Unlocks Silenced Enhancers for Reprogramming to Naive Pluripotency
    1
    1. scibot 13 Jan 2020
      Plasmid_71814

      DOI: 10.1016/j.stem.2018.05.020

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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1934590918302388