41 Matching Annotations
  1. Oct 2026
  2. www.sciencedirect.com www.sciencedirect.com
    A genome-scale adaptation map identifies the FANCM-RMI1/2 complex as an opposing modulator of cell fitness upon BRCA1 or BRCA2 loss
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    sciencedirect.com/science/article/pii/S109727652600660X
  3. Sep 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Abasic site repair in APE1-deficient mouse embryonic stem cells: a matter for the MRN complex and ATM signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC13601066/
  5. Jun 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cas9+ conditionally immortalized neutrophil progenitors as a tool for genome-wide CRISPR screening for neutrophil differentiation and function
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    pmc.ncbi.nlm.nih.gov/articles/PMC13233066/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Unbiased CRISPR synthetic lethal screening for genetic vulnerabilities in a succinate dehydrogenase-loss model of paraganglioma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13194163/
  8. dx.doi.org dx.doi.org
    PARP1 inhibition in naïve mouse embryonic stem cells induces viral mimicry
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    dx.doi.org/10.1093/nar/gkag537
  9. Apr 2026
  10. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004226012605-main-html.html
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    54.241.53.176/3f3b4decdd32d8a9053f30abfcb8282c7c4a442f/1-s2.0-S2589004226012605-main-html.html
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Minute amounts of helicase-deficient truncated RECQL4 are sufficient for DNA replication
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    pmc.ncbi.nlm.nih.gov/articles/PMC13076768/
  12. www.sciencedirect.com www.sciencedirect.com
    A genome-wide in vivo CRISPR screen identifies neuroprotective strategies in the mouse and human retina
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    sciencedirect.com/science/article/pii/S0896627326002138
  13. Mar 2026
  14. www.sciencedirect.com www.sciencedirect.com
    Tissue and CD4 T cell subset dependence on the amino acid transporter SLC38A1
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    sciencedirect.com/science/article/pii/S1550413126000859
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Cre-mediated copy number variant compromises the reliability of a LoxP-STOP-LoxP-PLAG1 driven brain tumor model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12932942/
  16. Feb 2026
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome-wide screens identify core regulators of cell surface prion protein expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12894898/
  18. Nov 2025
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Druggable genome CRISPR screening identifies the KEAP1/NRF2 axis as a mediator of PD-L1 expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12630863/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome-wide screen in Mycobacterium tuberculosis infected macrophages reveals innate regulation of antibacterial mediators by IRF2
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    pmc.ncbi.nlm.nih.gov/articles/PMC12621954/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting plasticity in the pyrimidine synthesis pathway potentiates macrophage-mediated phagocytosis in pancreatic cancer models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12618067/
  22. Sep 2025
  23. www.sciencedirect.com www.sciencedirect.com
    TELS1 stabilizes t-loops independently of TRF2 and controls telomere length in pluripotent cells
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    sciencedirect.com/science/article/pii/S2211124725010319
  24. Aug 2025
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SMARCA5 is required for the development of granule cell neuron precursors and Sonic Hedgehog Medulloblastoma growth
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12274346/
  26. Jul 2025
  27. www.biorxiv.org www.biorxiv.org
    Minute amounts of helicase-deficient truncated RECQL4 are sufficient for DNA replication
    1
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    biorxiv.org/content/10.1101/2025.07.21.666025v1
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Epigenetic regulation of neural stem cell aging in the mouse hippocampus by Setd8 downregulation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12218407/
  29. Jun 2025
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A genome-wide in vivo CRISPR screen identifies neuroprotective strategies in the mouse and human retina
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12148056/
  31. May 2025
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Med12 cooperates with multiple differentiation signals to facilitate efficient lineage transitions in embryonic stem cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12079664/
  33. Mar 2025
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A genome wide CRISPR screen reveals novel determinants of long-lived plasma cell secretory capacity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11888458/
  35. Dec 2024
  36. www.pnas.org www.pnas.org
    Docetaxel response in BRCA1,p53-deficient mammary tumor cells is affected by Huntingtin and BAP1
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    pnas.org/doi/abs/10.1073/pnas.2402849121
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Gliocidin is a nicotinamide-mimetic prodrug that targets glioblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11665509/
  38. Nov 2024
  39. www.biorxiv.org www.biorxiv.org
    Mannose receptor (MRC1) mediates uptake of dextran in macrophages via receptor-mediated endocytosis
    1
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    biorxiv.org/content/10.1101/2024.08.13.607841v1
  40. Sep 2024
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chromatin Regulator SMARCA4 Is Essential for MHV-Induced Inflammatory Cell Death, PANoptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11359047/
  42. Aug 2024
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vivo single-cell CRISPR uncovers distinct TNF programmes in tumour evolution
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    ncbi.nlm.nih.gov/pmc/articles/PMC11306103/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR-Cas9 knockout screens identify DNMT1 as a druggable dependency in sonic hedgehog medulloblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11304869/
  45. Jun 2024
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11182672/
  47. Mar 2024
  48. www.sciencedirect.com www.sciencedirect.com
    Multimodal stimulation screens reveal unique and shared genes limiting T cell fitness
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    sciencedirect.com/science/article/pii/S1535610824000606
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NINJ1 mediates inflammatory cell death, PANoptosis, and lethality during infection conditions and heat stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC10897308/
  50. Feb 2024
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome scale CRISPR screens identify actin capping proteins as key modulators of therapeutic responses to radiation and immunotherapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10827061/
  52. Dec 2023
  53. www.sciencedirect.com www.sciencedirect.com
    The ER stress sensor IRE1 interacts with STIM1 to promote store-operated calcium entry, T cell activation, and muscular differentiation
    1
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    sciencedirect.com/science/article/pii/S2211124723015528
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson’s disease-linked LRRK2 kinase
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    ncbi.nlm.nih.gov/pmc/articles/PMC10708890/
  55. Jul 2023
  56. www.sciencedirect.com www.sciencedirect.com
    MCK2-mediated MCMV infection of macrophages and virus dissemination to the salivary gland depends on MHC class I molecules
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    sciencedirect.com/science/article/pii/S2211124723006083
  57. Jun 2023
  58. www.sciencedirect.com www.sciencedirect.com
    An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets
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    sciencedirect.com/science/article/pii/S1535610823002088
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neuroprotective protein ADNP-dependent histone remodeling complex promotes T helper 2 immune cell differentiation
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    pmc.ncbi.nlm.nih.gov/articles/PMC10501989/
  60. Mar 2023
  61. www.nature.com www.nature.com
    Non-canonical functions of SNAIL drive context-specific cancer progression
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    nature.com/articles/s41467-023-36505-0
  62. Dec 2021
  63. www.sciencedirect.com www.sciencedirect.com
    Chronic calcium signaling in IgE+ B cells limits plasma cell differentiation and survival
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    sciencedirect.com/science/article/pii/S1074761321004970
  64. Nov 2021
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A genetic screen in macrophages identifies new regulators of IFNγ-inducible MHCII that contribute to T cell activation
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8598162/
  66. Sep 2021
  67. www.sciencedirect.com www.sciencedirect.com
    Lrp1 is a host entry factor for Rift Valley fever virus
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    sciencedirect.com/science/article/pii/S0092867421010485
  68. Apr 2021
  69. www.sciencedirect.com www.sciencedirect.com
    The dystonia gene THAP1 controls DNA double-strand break repair choice
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    sciencedirect.com/science/article/pii/S109727652100229X